Polygalic acid inhibits african swine fever virus polymerase activity: findings from machine learning and in vitro testing.

Choi, Jiwon; Lee, Hyundo; Cho, Soyoung; Choi, Yorim; Pham, Thuy X; Huynh, Trang T X; Lim, Yun-Sook; Hwang, Soon B

Choi, Jiwon; Lee, Hyundo; Cho, Soyoung; Choi, Yorim; Pham, Thuy X; Huynh, Trang T X; Lim, Yun-Sook; Hwang, Soon B.

Afiliação

Choi J; College of Pharmacy, Dongduk Women's University, Seoul, 02748, Republic of Korea. edccjw@gmail.com.
Lee H; College of Pharmacy, Dongduk Women's University, Seoul, 02748, Republic of Korea.
Cho S; College of Pharmacy, Dongduk Women's University, Seoul, 02748, Republic of Korea.
Choi Y; College of Pharmacy, Dongduk Women's University, Seoul, 02748, Republic of Korea.
Pham TX; Laboratory of RNA Viral Diseases, Korea Zoonosis Research Institute, Jeonbuk National University, Iksan, 54596, Republic of Korea.
Huynh TTX; Laboratory of RNA Viral Diseases, Korea Zoonosis Research Institute, Jeonbuk National University, Iksan, 54596, Republic of Korea.
Lim YS; Laboratory of RNA Viral Diseases, Korea Zoonosis Research Institute, Jeonbuk National University, Iksan, 54596, Republic of Korea. yunsolim@hanmail.net.
Hwang SB; Laboratory of RNA Viral Diseases, Korea Zoonosis Research Institute, Jeonbuk National University, Iksan, 54596, Republic of Korea.

J Comput Aided Mol Des ; 37(9): 453-461, 2023 09.

Article em En | MEDLINE | ID: mdl-37452977

Assuntos

Vírus da Febre Suína Africana; Febre Suína Africana; Humanos; Suínos; Animais; Febre Suína Africana/prevenção & controle; Simulação de Acoplamento Molecular; Proteínas Virais; Antivirais/farmacologia; Técnicas In Vitro; Aprendizado de Máquina

Palavras-chave

African swine fever virus; AsfvPolX polymerase; Machine learning; Natural products; Polygalic acid

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Febre Suína Africana / Vírus da Febre Suína Africana Tipo de estudo: Diagnostic_studies / Guideline / Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Comput Aided Mol Des Assunto da revista: BIOLOGIA MOLECULAR / ENGENHARIA BIOMEDICA Ano de publicação: 2023 Tipo de documento: Article

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