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Identification of new PTP1B-inhibiting decipiene diterpenoid esters from Eremophila clarkei by high-resolution PTP1B inhibition profiling, enzyme kinetics analysis, and molecular docking.
Liang, Chao; Zang, Jie; Ndi, Chi; Semple, Susan J; Buirchell, Bevan; Coriani, Sonia; Møller, Birger Lindberg; Staerk, Dan.
Afiliação
  • Liang C; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark.
  • Zang J; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark.
  • Ndi C; Quality Use of Medicines and Pharmacy Research Centre, Clinical and Health Sciences, University of South Australia, Frome Road, Adelaide 5000, Australia.
  • Semple SJ; Quality Use of Medicines and Pharmacy Research Centre, Clinical and Health Sciences, University of South Australia, Frome Road, Adelaide 5000, Australia.
  • Buirchell B; Wise Owl Consulting, Como, Western Australia 6152, Australia.
  • Coriani S; Department of Chemistry, Technical University of Denmark, Kemitorvet Building 207, DK-2800 Kongens Lyngby, Denmark.
  • Møller BL; Plant Biochemistry Laboratory, Department of Plant and Environmental Sciences, University of Copenhagen, Thorvaldsensvej 40, DK-1871 Frederiksberg C, Denmark.
  • Staerk D; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark. Electronic address: ds@sund.ku.dk.
Bioorg Chem ; 139: 106744, 2023 10.
Article em En | MEDLINE | ID: mdl-37517158
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Diterpenos Tipo de estudo: Diagnostic_studies Idioma: En Revista: Bioorg Chem Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Dinamarca
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Diterpenos Tipo de estudo: Diagnostic_studies Idioma: En Revista: Bioorg Chem Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Dinamarca