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Incorporating Uremic Solute-mediated Inhibition of OAT1/3 Improves PBPK Prediction of Tenofovir Renal and Systemic Disposition in Patients with Severe Kidney Disease.
Chang, Shih-Yu; Huang, Weize; Chapron, Alenka; Quiñones, Antonio J López; Wang, Joanne; Isoherranen, Nina; Shen, Danny D; Kelly, Edward J; Himmelfarb, Jonathan; Yeung, Catherine K.
Afiliação
  • Chang SY; Department of Pharmacy, School of Pharmacy, University of Washington, 1959 NE Pacific St. H375, Box 357630, Seattle, WA, 98195, USA.
  • Huang W; Janssen Research and Development, Raritan, NJ, USA.
  • Chapron A; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA, 98195, USA.
  • Quiñones AJL; Genentech Inc, South San Francisco, CA, USA.
  • Wang J; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA, 98195, USA.
  • Isoherranen N; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA, 98195, USA.
  • Shen DD; Revolution Medicines, San Francisco, CA, USA.
  • Kelly EJ; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA, 98195, USA.
  • Himmelfarb J; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA, 98195, USA.
  • Yeung CK; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA, 98195, USA.
Pharm Res ; 40(11): 2597-2606, 2023 Nov.
Article em En | MEDLINE | ID: mdl-37704895
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Insuficiência Renal Crônica / Rim Tipo de estudo: Guideline / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Pharm Res Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Insuficiência Renal Crônica / Rim Tipo de estudo: Guideline / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Pharm Res Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos