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Postoperative Hypoalbuminemia as a Predictor of Acute Kidney Injury After Open Repair of Ruptured Abdominal Aortic Aneurysm.
Yoon, Hei Jin; Kim, Tae-Hoon; Ko, Da Eun; Song, Jong-Wook; Min, Narhyun; Ham, Sung Yeon.
Afiliação
  • Yoon HJ; Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, South Korea.
  • Kim TH; Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine, Seoul, South Korea.
  • Ko DE; Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, South Korea.
  • Song JW; Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, South Korea.
  • Min N; Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, South Korea.
  • Ham SY; Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, South Korea.
World J Surg ; 47(12): 3382-3393, 2023 Dec.
Article em En | MEDLINE | ID: mdl-37730902
ABSTRACT

BACKGROUND:

Perioperative hypoalbuminemia has a prognostic effect on mortality and morbidity in various cohorts. Patients undergoing open repair of ruptured abdominal aortic aneurysms (rAAA) are at a high risk of hypoalbuminemia due to bleeding and underlying diseases. Hence, this study aimed to investigate the predictive value of immediate postoperative hypoalbuminemia for the risk for acute kidney injury (AKI) in patients undergoing open rAAA repair.

METHODS:

We retrospectively reviewed 143 patients who underwent open rAAA repair between January 2008 and May 2022. The patients were divided into two groups according to the presence of postoperative AKI. The perioperative serum albumin levels of the two groups were compared. The patients were further divided into two groups based on the median immediate postoperative albumin level (2.4 g/dL). The incidence of AKI was compared between the two groups. Multivariate logistic regression analysis was performed to assess the predictors of postoperative AKI. Kaplan-Meier survival curves were used to evaluate potential of AKI and albumin level as prognostic factors for mortality.

RESULTS:

Immediate postoperative serum albumin was significantly lower in the AKI group than in the non-AKI group (2.11 ± 0.62 g/dL vs. 2.59 ± 0.62 g/dL, p < 0.001). The incidence of postoperative AKI was significantly higher in patients with albumin ≤ 2.4 g/dL than in patients with albumin > 2.4 g/dL (53.8% vs. 27.7%, p = 0.002). Immediate postoperative albumin level was an independent predictor of AKI (Odds ratio [OR], 0.310; 95% confidence interval [CI] 0.165-0.583, p < 0.001) and 1-year mortality (OR, 0.230; 95% CI 0.098-0.542, p = 0.001).

CONCLUSIONS:

Immediate postoperative hypoalbuminemia was associated with postoperative AKI and mortality in patients with rAAA.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ruptura Aórtica / Aneurisma da Aorta Abdominal / Implante de Prótese Vascular / Hipoalbuminemia / Injúria Renal Aguda Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: World J Surg Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Coréia do Sul

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ruptura Aórtica / Aneurisma da Aorta Abdominal / Implante de Prótese Vascular / Hipoalbuminemia / Injúria Renal Aguda Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: World J Surg Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Coréia do Sul