BMP6 participates in the pathogenesis of adolescent idiopathic scoliosis by regulating osteopenia.

Tang, Hao; Li, Jiong; Li, Jia-Ke; He, Si-Han; Xiang, Gang; Rong, Rong; Liang, Zhuo-Tao; Zhang, Hong-Qi

Tang, Hao; Li, Jiong; Li, Jia-Ke; He, Si-Han; Xiang, Gang; Rong, Rong; Liang, Zhuo-Tao; Zhang, Hong-Qi.

Afiliação

Tang H; Department of Spine Surgery and Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.
Li J; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.
Li JK; Department of Spine Surgery and Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.
He SH; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.
Xiang G; Department of General Surgery, The Third Xiangya Hospital of Central South University, Changsha, People's Republic of China.
Rong R; Department of Spine Surgery and Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.
Liang ZT; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.
Zhang HQ; Department of Spine Surgery and Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.

J Cell Physiol ; 238(11): 2586-2599, 2023 11.

Article em En | MEDLINE | ID: mdl-37795636

Assuntos

Doenças Ósseas Metabólicas; Escoliose; Humanos; Adolescente; Animais; Escoliose/genética; Escoliose/patologia; Osteogênese/genética; Peixe-Zebra/genética; Coluna Vertebral/metabolismo; Diferenciação Celular/genética; Doenças Ósseas Metabólicas/genética; Doenças Ósseas Metabólicas/metabolismo; Células Cultivadas; Células da Medula Óssea/metabolismo; Proteína Morfogenética Óssea 6/genética

Palavras-chave

BMP6; CAP1-217; adipogenic differentiation; adolescent idiopathic scoliosis (AIS); bone marrow-derived mesenchymal stem cells (BMSCs); osteogenic differentiation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Escoliose / Doenças Ósseas Metabólicas Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Adolescent / Animals / Humans Idioma: En Revista: J Cell Physiol Ano de publicação: 2023 Tipo de documento: Article

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