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Predictors for spinal deformity following resection of intramedullary tumor via posterior approach: a systematic review and meta-analysis.
Szyduczynski, Maciej; Korneliussen, Johannes; Landé, Oscar; Krakowiak, Michal; Szmuda, Tomasz; Miekisiak, Grzegorz.
Afiliação
  • Szyduczynski M; Scientific Circle of Neurosurgery, Neurosurgery Department, Medical University of Gdansk, Gdansk, Poland.
  • Korneliussen J; Scientific Circle of Neurosurgery, Neurosurgery Department, Medical University of Gdansk, Gdansk, Poland.
  • Landé O; Scientific Circle of Neurosurgery, Neurosurgery Department, Medical University of Gdansk, Gdansk, Poland.
  • Krakowiak M; Neurosurgery Department, Medical University of Gdansk, Gdansk, Poland.
  • Szmuda T; Neurosurgery Department, Medical University of Gdansk, Gdansk, Poland.
  • Miekisiak G; Institute of Medicine, Opole University, Opole, Poland. gmiekisiak@gmail.com.
Eur Spine J ; 32(12): 4355-4361, 2023 12.
Article em En | MEDLINE | ID: mdl-37805564
PURPOSE: The present study aimed to identify the clinical predictive factors for worsened spinal deformity (SD) following surgical resection via posterior approach for primary intramedullary tumors. METHODS: A systematic search was performed using PubMed, Web of Science, and Scopus databases to extract potential references. Observational studies reporting predictive factors for worsened SD following surgical resection via posterior approach for primary intramedullary tumors were included. The odds ratio (OR) was calculated for dichotomous parameters. RESULTS: Four retrospective cohort studies were included in the meta-analysis. They were comprised of two groups of patients; those who developed SD (n = 87) and those who did not (n = 227). For patients with IMSCTs, age under 25 years as well as age under 13 years were the demographic variables associated with postoperative SD (odds ratio [OR] 3.92; p = 0.0002 and OR 4.22; p = 0.003). In both the fusion and the non-fusion subgroups, preoperative spinal deformity strongly predicted postoperative SD (OR 11.94; p < 0.001), with the risk highly elevated among the non-fusion patients (OR 24.64; p < 0.0002). Thoracolumbar junction involvement was also found to be a predictor of postoperative SD for patients with IMSCT (OR 2.89; p = 0.02). CONCLUSION: This study highlights the importance of considering age, preoperative spinal deformity, and thoracolumbar junction involvement as predictors of postoperative spinal deformity following surgical resection for IMSCT. These findings may provide guidance for the management of these patients, including the development of preoperative planning strategies and the selection of the most appropriate surgical approach for high-risk patients.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Medula Espinal / Fusão Vertebral Tipo de estudo: Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Adolescent / Adult / Humans Idioma: En Revista: Eur Spine J Assunto da revista: ORTOPEDIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Polônia

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Medula Espinal / Fusão Vertebral Tipo de estudo: Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Adolescent / Adult / Humans Idioma: En Revista: Eur Spine J Assunto da revista: ORTOPEDIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Polônia