Integration of an LPAR1 Antagonist into Liposomes Enhances Their Internalization and Tumor Accumulation in an Animal Model of Human Metastatic Breast Cancer.

Abdelmessih, Rudolf G; Xu, Jiaming; Hung, Francisco R; Auguste, Debra T

Abdelmessih, Rudolf G; Xu, Jiaming; Hung, Francisco R; Auguste, Debra T.

Afiliação

Abdelmessih RG; Department of Chemical Engineering, Northeastern University, 360 Huntington Avenue, Boston, Massachusetts 02115, United States.
Xu J; Department of Chemical Engineering, Northeastern University, 360 Huntington Avenue, Boston, Massachusetts 02115, United States.
Hung FR; Department of Chemical Engineering, Northeastern University, 360 Huntington Avenue, Boston, Massachusetts 02115, United States.
Auguste DT; Department of Chemical Engineering, Northeastern University, 360 Huntington Avenue, Boston, Massachusetts 02115, United States.

Mol Pharm ; 20(11): 5500-5514, 2023 11 06.

Article em En | MEDLINE | ID: mdl-37844135

Assuntos

Neoplasias da Mama; Lipossomos; Humanos; Camundongos; Animais; Feminino; Neoplasias da Mama/tratamento farmacológico; Bicamadas Lipídicas; Modelos Animais de Doenças; Receptores de Ácidos Lisofosfatídicos/metabolismo

Palavras-chave

Ki161425; LPAR1; LPAR1 antagonist; drug delivery; metastatic breast cancer; molecular dynamics simulation

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Lipossomos Limite: Animals / Female / Humans Idioma: En Revista: Mol Pharm Assunto da revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google