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Predicting Colloidal Stability of High-Concentration Monoclonal Antibody Formulations in Common Pharmaceutical Buffers Using Improved Polyethylene Glycol Induced Protein Precipitation Assay.
Meza, Noemi P; Hardy, Colin A; Morin, Kylie H; Huang, Chengbin; Raghava, Smita; Song, Jing; Zhang, Jingtao; Wang, Ying.
Afiliação
  • Meza NP; Department of Chemistry and Biochemistry, University of North Carolina Wilmington, Wilmington, North Carolina 28403, United States.
  • Hardy CA; Department of Chemistry and Biochemistry, University of North Carolina Wilmington, Wilmington, North Carolina 28403, United States.
  • Morin KH; Department of Chemistry and Biochemistry, University of North Carolina Wilmington, Wilmington, North Carolina 28403, United States.
  • Huang C; Analytical Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
  • Raghava S; Sterile and Specialty Products, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
  • Song J; Analytical Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
  • Zhang J; Analytical Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
  • Wang Y; Department of Chemistry and Biochemistry, University of North Carolina Wilmington, Wilmington, North Carolina 28403, United States.
Mol Pharm ; 20(11): 5842-5855, 2023 11 06.
Article em En | MEDLINE | ID: mdl-37867303
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polietilenoglicóis / Anticorpos Monoclonais Idioma: En Revista: Mol Pharm Assunto da revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polietilenoglicóis / Anticorpos Monoclonais Idioma: En Revista: Mol Pharm Assunto da revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos