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The unique ORF8 protein from SARS-CoV-2 binds to human dendritic cells and induces a hyper-inflammatory cytokine storm.
Hamdorf, Matthias; Imhof, Thomas; Bailey-Elkin, Ben; Betz, Janina; Theobald, Sebastian J; Simonis, Alexander; Di Cristanziano, Veronica; Gieselmann, Lutz; Dewald, Felix; Lehmann, Clara; Augustin, Max; Klein, Florian; Alcazar, Miguel A Alejandre; Rongisch, Robert; Fabri, Mario; Rybniker, Jan; Goebel, Heike; Stetefeld, Jörg; Brachvogel, Bent; Cursiefen, Claus; Koch, Manuel; Bock, Felix.
Afiliação
  • Hamdorf M; Cornea Lab Experimental Ophthalmology, Department of Ophthalmology, Faculty of Medicine and University Hospital Cologne, 50937 Cologne, Germany.
  • Imhof T; Terasaki Institute for Biomedical Innovation, Los Angeles, CA 90024, USA.
  • Bailey-Elkin B; Center for Biochemistry, Faculty of Medicine and University Hospital Cologne, 50931 Cologne, Germany.
  • Betz J; Institute for Experimental Dentistry and Oral Musculoskeletal Biology, Faculty of Medicine and University Hospital Cologne, 50931 Cologne, Germany.
  • Theobald SJ; Department of Microbiology, University of Manitoba, Winnipeg MB R3B 2E9 Manitoba, Canada.
  • Simonis A; Center for Biochemistry, Faculty of Medicine and University Hospital Cologne, 50931 Cologne, Germany.
  • Di Cristanziano V; Institute for Experimental Dentistry and Oral Musculoskeletal Biology, Faculty of Medicine and University Hospital Cologne, 50931 Cologne, Germany.
  • Gieselmann L; Department I of Internal Medicine, Division of Infectious Diseases, Faculty of Medicine and University Hospital Cologne, 50937 Cologne, Germany.
  • Dewald F; Center for Molecular Medicine Cologne, University of Cologne, 50931 Cologne, Germany.
  • Lehmann C; Department I of Internal Medicine, Division of Infectious Diseases, Faculty of Medicine and University Hospital Cologne, 50937 Cologne, Germany.
  • Augustin M; Center for Molecular Medicine Cologne, University of Cologne, 50931 Cologne, Germany.
  • Klein F; Institute of Virology, Faculty of Medicine and University Hospital Cologne, 50935 Cologne, Germany.
  • Alcazar MAA; Institute of Virology, Faculty of Medicine and University Hospital Cologne, 50935 Cologne, Germany.
  • Rongisch R; Institute of Virology, Faculty of Medicine and University Hospital Cologne, 50935 Cologne, Germany.
  • Fabri M; Department I of Internal Medicine, Division of Infectious Diseases, Faculty of Medicine and University Hospital Cologne, 50937 Cologne, Germany.
  • Rybniker J; Center for Molecular Medicine Cologne, University of Cologne, 50931 Cologne, Germany.
  • Goebel H; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, 50931 Cologne, Germany.
  • Stetefeld J; Department I of Internal Medicine, Division of Infectious Diseases, Faculty of Medicine and University Hospital Cologne, 50937 Cologne, Germany.
  • Brachvogel B; Center for Molecular Medicine Cologne, University of Cologne, 50931 Cologne, Germany.
  • Cursiefen C; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, 50931 Cologne, Germany.
  • Koch M; Institute of Virology, Faculty of Medicine and University Hospital Cologne, 50935 Cologne, Germany.
  • Bock F; Center for Molecular Medicine Cologne, University of Cologne, 50931 Cologne, Germany.
J Mol Cell Biol ; 2023 Oct 27.
Article em En | MEDLINE | ID: mdl-37891014
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Mol Cell Biol Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Mol Cell Biol Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha