SFTSV Gn-Head mRNA vaccine confers efficient protection against lethal viral challenge.

Kim, Dokyun; Lai, Chih-Jen; Cha, Inho; Kang, Seokmin; Yang, Wan-Shan; Choi, Younho; Jung, Jae U

Kim, Dokyun; Lai, Chih-Jen; Cha, Inho; Kang, Seokmin; Yang, Wan-Shan; Choi, Younho; Jung, Jae U.

Afiliação

Kim D; Department of Cancer Biology and Infection Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Lai CJ; Global Center for Pathogen Research and Human Health, Lerner Research Institute, Cleveland Clinic, Ohio, USA.
Cha I; Department of Cancer Biology and Infection Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Kang S; Global Center for Pathogen Research and Human Health, Lerner Research Institute, Cleveland Clinic, Ohio, USA.
Yang WS; Department of Cancer Biology and Infection Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Choi Y; Department of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Jung JU; Department of Cancer Biology and Infection Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA.

J Med Virol ; 95(11): e29203, 2023 11.

Article em En | MEDLINE | ID: mdl-37909776

Assuntos

Phlebovirus; Proteínas do Envelope Viral; Animais; Camundongos; Proteínas do Envelope Viral/genética; Phlebovirus/genética; Vacinas Sintéticas; RNA Mensageiro/genética; Vacinas de mRNA

Palavras-chave

Gn-H; ferritin nanoparticle; mRNA vaccine; severe fever with thrombocytopenia syndrome virus; tick-borne virus

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas do Envelope Viral / Phlebovirus Limite: Animals Idioma: En Revista: J Med Virol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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