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Discovery of Orally Bioavailable Phthalazinone Analogues as an ENPP1 Inhibitor for STING-Mediated Cancer Immunotherapy.
Cho, Yeonguk; Kang, Miso; Ji, Su Hyun; Jeong, Hee Jin; Jung, Jae Eun; Oh, Do Hee; Park, Sunyoung; Park, Yong-Yea; Choi, Junghwan; Kim, Sungjoon; Kim, Nam-Jung; Lee, Duck-Hyung; Park, Chan Sun; Han, Seo-Jung; Lee, Sanghee; Choi, Junwon.
Afiliação
  • Cho Y; Department of Molecular Science and Technology, Ajou University, Suwon 16499, Republic of Korea.
  • Kang M; Department of Fundamental Pharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea.
  • Ji SH; Brain Science Institute, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea.
  • Jeong HJ; Chemical and Biological Integrative Research Center, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea.
  • Jung JE; Department of Chemistry, Sogang University, Seoul 04107, Republic of Korea.
  • Oh DH; Chemical and Biological Integrative Research Center, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea.
  • Park S; Chemical and Biological Integrative Research Center, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea.
  • Park YY; Chemical and Biological Integrative Research Center, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea.
  • Choi J; Txinno Bioscience Inc., Yongin 16942, Republic of Korea.
  • Kim S; Txinno Bioscience Inc., Yongin 16942, Republic of Korea.
  • Kim NJ; Txinno Bioscience Inc., Yongin 16942, Republic of Korea.
  • Lee DH; Txinno Bioscience Inc., Yongin 16942, Republic of Korea.
  • Park CS; Department of Fundamental Pharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea.
  • Han SJ; Department of Chemistry, Sogang University, Seoul 04107, Republic of Korea.
  • Lee S; Txinno Bioscience Inc., Yongin 16942, Republic of Korea.
  • Choi J; Chemical and Biological Integrative Research Center, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea.
J Med Chem ; 66(22): 15141-15170, 2023 11 23.
Article em En | MEDLINE | ID: mdl-37963811

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diester Fosfórico Hidrolases / Neoplasias Limite: Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diester Fosfórico Hidrolases / Neoplasias Limite: Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2023 Tipo de documento: Article