Design, Synthesis, Electrochemical, and Biological Evaluation of Fluorescent Chlorido[<i>N</i>,<i>N</i>'-bis(methoxy/hydroxy)salicylidene-1,2-bis(4-methoxyphenyl)ethylenediamine]iron(III) Complexes as Anticancer Agents.

Bernkop-Schnürch, Astrid Dagmar; Chavooshi, Donja; Descher, Hubert Aaron; Leitner, Daniel; Talasz, Heribert; Hermann, Martin; Wurst, Klaus; Hohloch, Stephan; Gust, Ronald; Kircher, Brigitte

Design, Synthesis, Electrochemical, and Biological Evaluation of Fluorescent Chlorido[N,N'-bis(methoxy/hydroxy)salicylidene-1,2-bis(4-methoxyphenyl)ethylenediamine]iron(III) Complexes as Anticancer Agents.

Bernkop-Schnürch, Astrid Dagmar; Chavooshi, Donja; Descher, Hubert Aaron; Leitner, Daniel; Talasz, Heribert; Hermann, Martin; Wurst, Klaus; Hohloch, Stephan; Gust, Ronald; Kircher, Brigitte.

Afiliação

Bernkop-Schnürch AD; Department of Pharmaceutical Chemistry, Institute of Pharmacy, CMBI-Center for Molecular Biosciences Innsbruck, CCBâCenter for Chemistry and Biomedicine, University of Innsbruck, Innrain 80-82, 6020 Innsbruck, Austria.
Chavooshi D; Department of Pharmaceutical Chemistry, Institute of Pharmacy, CMBI-Center for Molecular Biosciences Innsbruck, CCBâCenter for Chemistry and Biomedicine, University of Innsbruck, Innrain 80-82, 6020 Innsbruck, Austria.
Descher HA; Immunobiology and Stem Cell Laboratory, Department of Internal Medicine V (Hematology and Oncology), Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.
Leitner D; Department of Pharmaceutical Chemistry, Institute of Pharmacy, CMBI-Center for Molecular Biosciences Innsbruck, CCBâCenter for Chemistry and Biomedicine, University of Innsbruck, Innrain 80-82, 6020 Innsbruck, Austria.
Talasz H; Department of General, Inorganic and Theoretical Chemistry, University of Innsbruck, Innrain 80-82, 6020 Innsbruck, Austria.
Hermann M; Biocenter, Institute of Medical Biochemistry, Protein Core Facility, Medical University of Innsbruck, Innrain 80-82, 6020 Innsbruck, Austria.
Wurst K; Department of Anesthesiology and Critical Care Medicine, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.
Hohloch S; Department of General, Inorganic and Theoretical Chemistry, University of Innsbruck, Innrain 80-82, 6020 Innsbruck, Austria.
Gust R; Department of General, Inorganic and Theoretical Chemistry, University of Innsbruck, Innrain 80-82, 6020 Innsbruck, Austria.
Kircher B; Department of Pharmaceutical Chemistry, Institute of Pharmacy, CMBI-Center for Molecular Biosciences Innsbruck, CCBâCenter for Chemistry and Biomedicine, University of Innsbruck, Innrain 80-82, 6020 Innsbruck, Austria.

J Med Chem ; 66(23): 15916-15925, 2023 12 14.

Article em En | MEDLINE | ID: mdl-38013413

Assuntos

Antineoplásicos; Ferro; Humanos; Antineoplásicos/química; Morte Celular; Linhagem Celular Tumoral; Etilenodiaminas/farmacologia; Etilenodiaminas/química; Ferro/química; Complexos de Coordenação/química

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ferro / Antineoplásicos Limite: Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Áustria

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