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Enhancing anti-AML activity of venetoclax by isoflavone ME-344 through suppression of OXPHOS and/or purine biosynthesis in vitro.
Hurrish, Katie H; Su, Yongwei; Patel, Shraddha; Ramage, Cassandra L; Zhao, Jianlei; Temby, Brianna R; Carter, Jenna L; Edwards, Holly; Buck, Steven A; Wiley, Sandra E; Hüttemann, Maik; Polin, Lisa; Kushner, Juiwanna; Dzinic, Sijana H; White, Kathryn; Bao, Xun; Li, Jing; Yang, Jay; Boerner, Julie; Hou, Zhanjun; Al-Atrash, Gheath; Konoplev, Sergej N; Busquets, Jonathan; Tiziani, Stefano; Matherly, Larry H; Taub, Jeffrey W; Konopleva, Marina; Ge, Yubin; Baran, Natalia.
Afiliação
  • Hurrish KH; Cancer Biology Graduate Program, Wayne State University School of Medicine, Detroit, MI, USA.
  • Su Y; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA; Molecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA.
  • Patel S; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Ramage CL; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Zhao J; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA; Molecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA.
  • Temby BR; Cancer Biology Graduate Program, Wayne State University School of Medicine, Detroit, MI, USA.
  • Carter JL; Cancer Biology Graduate Program, Wayne State University School of Medicine, Detroit, MI, USA; MD/PhD Program, Wayne State University School of Medicine, Detroit, MI, USA.
  • Edwards H; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA; Molecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA.
  • Buck SA; Division of Pediatric Hematology/Oncology, Children's Hospital of Michigan, Detroit, MI, USA.
  • Wiley SE; MEI Pharma, Inc., San Diego, CA, USA.
  • Hüttemann M; Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI, USA.
  • Polin L; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA; Molecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA.
  • Kushner J; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA; Molecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA.
  • Dzinic SH; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA; Molecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA.
  • White K; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA; Molecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA.
  • Bao X; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA; Molecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA.
  • Li J; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA; Molecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA.
  • Yang J; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA; Molecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA.
  • Boerner J; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA; Molecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA.
  • Hou Z; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA; Molecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA.
  • Al-Atrash G; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Konoplev SN; Department of Leukemia, MD Anderson Cancer Center, The University of Texas, Houston, TX, USA.
  • Busquets J; Department of Nutritional Sciences, The University of Texas at Austin, Austin, TX, USA.
  • Tiziani S; Department of Nutritional Sciences, The University of Texas at Austin, Austin, TX, USA.
  • Matherly LH; Cancer Biology Graduate Program, Wayne State University School of Medicine, Detroit, MI, USA; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA; Molecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit
  • Taub JW; Molecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA; Division of Pediatric Hematology/Oncology, Children's Hospital of Michigan, Detroit, MI, USA; Department of Pediatrics, Wayne State University School of Medicine, Detro
  • Konopleva M; Department of Leukemia, MD Anderson Cancer Center, The University of Texas, Houston, TX, USA. Electronic address: Marina.Konopleva@einsteinmed.edu.
  • Ge Y; Cancer Biology Graduate Program, Wayne State University School of Medicine, Detroit, MI, USA; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA; Molecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit
  • Baran N; Department of Leukemia, MD Anderson Cancer Center, The University of Texas, Houston, TX, USA. Electronic address: NBaran@mdanderson.org.
Biochem Pharmacol ; 220: 115981, 2024 Feb.
Article em En | MEDLINE | ID: mdl-38081370
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfonamidas / Leucemia Mieloide Aguda / Isoflavonas Limite: Animals / Humans Idioma: En Revista: Biochem Pharmacol Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfonamidas / Leucemia Mieloide Aguda / Isoflavonas Limite: Animals / Humans Idioma: En Revista: Biochem Pharmacol Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos