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Generation of a control iPS cell line (JUCGRMi006-A) with no abnormalities in Parkinson's disease-related genes.
Ishikawa, Kei-Ichi; Shiga, Takahiro; Funayama, Manabu; Hattori, Nobutaka; Akamatsu, Wado.
Afiliação
  • Ishikawa KI; Center for Genomic and Regenerative Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan; Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan; Department of Research and Development for Organoids, Juntendo University School of Medicine, Tokyo, Japan. Elec
  • Shiga T; Center for Genomic and Regenerative Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
  • Funayama M; Center for Genomic and Regenerative Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan; Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan; Research Institute for Diseases of Old Age, Juntendo University Graduate School of Medicine, Tokyo, Japan.
  • Hattori N; Center for Genomic and Regenerative Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan; Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan; Department of Research and Development for Organoids, Juntendo University School of Medicine, Tokyo, Japan; Neur
  • Akamatsu W; Center for Genomic and Regenerative Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Stem Cell Res ; 74: 103270, 2024 02.
Article em En | MEDLINE | ID: mdl-38100911
ABSTRACT
The appropriate control of induced pluripotent stem cells (iPSCs) is essential for studying iPSCs derived from patients with Parkinson's disease (PD). Here, we established an iPSC line from a healthy female donor. The iPSCs were pluripotent, could differentiate into three germ layers, and had normal karyotypes. We also confirmed that the iPSC line exhibited no PD-related gene abnormalities. This iPSC line will be useful for PD research.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Células-Tronco Pluripotentes Induzidas Limite: Female / Humans Idioma: En Revista: Stem Cell Res Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Células-Tronco Pluripotentes Induzidas Limite: Female / Humans Idioma: En Revista: Stem Cell Res Ano de publicação: 2024 Tipo de documento: Article