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Improving Guideline-Directed Medical Therapy for Patients With Heart Failure With Reduced Ejection Fraction: A Review of Implementation Strategies.
Harrington, Josephine; Rao, Vishal N; Leyva, Monica; Oakes, Megan; Mentz, Robert J; Bosworth, Hayden B; Pagidipati, Neha J.
Afiliação
  • Harrington J; Department of Medicine, Division of Cardiology Duke University, Durham, NC; Duke Clinical Research Institute, Durham, NC. Electronic address: Josephine.harrington@duke.edu.
  • Rao VN; Department of Medicine, Division of Cardiology Duke University, Durham, NC; Duke Clinical Research Institute, Durham, NC.
  • Leyva M; Department of Population Health Sciences, Durham, NC.
  • Oakes M; Department of Population Health Sciences, Durham, NC.
  • Mentz RJ; Department of Medicine, Division of Cardiology Duke University, Durham, NC; Duke Clinical Research Institute, Durham, NC.
  • Bosworth HB; Department of Medicine, Division of Cardiology Duke University, Durham, NC; Department of Population Health Sciences, Durham, NC.
  • Pagidipati NJ; Department of Medicine, Division of Cardiology Duke University, Durham, NC; Duke Clinical Research Institute, Durham, NC.
J Card Fail ; 30(2): 376-390, 2024 Feb.
Article em En | MEDLINE | ID: mdl-38142886
ABSTRACT
Despite recent advances in the use of guideline-directed medical therapy (GDMT) for patients with heart failure with reduced ejection fraction (HFrEF), achievement of target GDMT use and up-titration to goal dosages continue to be modest. In recent years, a number of interventional approaches to improve the usage of GDMT have been published, but many are limited by single-center experiences with small sample sizes. However, strategies including the use of multidisciplinary teams, dedicated GDMT titration algorithms and clinician audits with feedback have shown promise. There remains a critical need for large, rigorous trials to assess the utility of differing interventions to improve the use and titration of GDMT in HFrEF. Here, we review existing literature in GDMT implementation for those with HFrEF and discuss future directions and considerations in the field.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Disfunção Ventricular Esquerda / Insuficiência Cardíaca Limite: Humans Idioma: En Revista: J Card Fail Assunto da revista: CARDIOLOGIA Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Disfunção Ventricular Esquerda / Insuficiência Cardíaca Limite: Humans Idioma: En Revista: J Card Fail Assunto da revista: CARDIOLOGIA Ano de publicação: 2024 Tipo de documento: Article