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Recent advances in carbon quantum dots for gene delivery: A comprehensive review.
Othman, Hazha Omar; Anwer, Esra Tariq; Ali, Diyar Salahuddin; Hassan, Rebwar Omar; Mahmood, Elnaz Ehsan; Ahmed, Rayan Abubakir; Muhammad, Rozhan Fathulla; Smaoui, Slim.
Afiliação
  • Othman HO; Department of Chemistry, College of Science, Salahaddin University-Erbil, Erbil, Iraq.
  • Anwer ET; Department of Pharmaceutics, Faculty of Pharmacy, Tishk International University, Erbil, Iraq.
  • Ali DS; Department of Pharmaceutics, Faculty of Pharmacy, Tishk International University, Erbil, Iraq.
  • Hassan RO; Department of Chemistry, College of Science, Salahaddin University-Erbil, Erbil, Iraq.
  • Mahmood EE; Department of Pharmacy, College of Pharmacy, Knowledge University, Erbil, Iraq.
  • Ahmed RA; Department of Chemistry, College of Science, Salahaddin University-Erbil, Erbil, Iraq.
  • Muhammad RF; Department of Radiological Imaging Technology, College of Health Technology, Cihan University-Erbil, Iraq.
  • Smaoui S; Department of Pharmaceutics, Faculty of Pharmacy, Tishk International University, Erbil, Iraq.
J Cell Physiol ; 2024 Mar 07.
Article em En | MEDLINE | ID: mdl-38454776
ABSTRACT
Gene therapy is a revolutionary technology in healthcare that provides novel therapeutic options and has immense potential in addressing genetic illnesses, malignancies, and viral infections. Nevertheless, other obstacles still need to be addressed regarding safety, ethical implications, and technological enhancement. Nanotechnology and gene therapy fields have shown significant promise in transforming medical treatments by improving accuracy, effectiveness, and personalization. This review assesses the possible uses of gene therapy, its obstacles, and future research areas, specifically emphasizing the creative combination of gene therapy and nanotechnology. Nanotechnology is essential for gene delivery as it allows for the development of nano-scale carriers, such as carbon quantum dots (CQDs), which may effectively transport therapeutic genes into specific cells. CQDs exhibit distinctive physicochemical characteristics such as small size, excellent stability, and minimal toxicity, which render them highly favorable for gene therapy applications. The objective of this study is to review and describe the current advancements in the utilization of CQDs for gene delivery. Additionally, it intends to assess existing research, explore novel applications, and identify future opportunities and obstacles. This study offers a thorough summary of the current state and future possibilities of using CQDs for gene delivery. Combining recent research findings highlights the potential of CQDs to revolutionize gene therapy and its delivery methods.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Cell Physiol Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Iraque

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Cell Physiol Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Iraque