Light-Driven Photocatalyst-Free Synthesis of ß, δ-Functionalized Ketones from Aldehydes.
J Org Chem
; 89(7): 5189-5199, 2024 Apr 05.
Article
em En
| MEDLINE
| ID: mdl-38511413
ABSTRACT
The synthesis of ketones has been a long focus of chemistry research, on account of its unique reactivity. Herein, we report a simple light-driven photocatalyst-free synthesis of ß, δ-functionalized ketones from aldehydes, using inexpensive and commercially abundant feedstock chemicals. This reaction is enabled by the direct acyl radical generation via hydrogen atom transfer and the subsequent radical addition process, avoiding the need for prefunctionalized substrates and organometallic reagent.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
J Org Chem
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
China