Efficient total synthesis of three alpinoids via the Au(I)-catalyzed Meyer-Schuster rearrangement.
Tetrahedron Lett
; 1042022 Aug 17.
Article
em En
| MEDLINE
| ID: mdl-38584726
ABSTRACT
The total syntheses of three structurally related natural products, deoxyalpinoid B, deoxyalpinoid A, and alpinoid F, are reported, and each features a Au(I)-catalyzed Meyer-Schuster rearrangement as the key step. The synthesis of alpinoid F is reported for the first time. The syntheses of these natural products, all of which exhibit potent anticancer activity, are readily amenable to the preparation of structural analogs.
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1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Tetrahedron Lett
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Estados Unidos