The Emerging Role of Natural Products in Cancer Treatment.
Arch Toxicol
; 98(8): 2353-2391, 2024 Aug.
Article
em En
| MEDLINE
| ID: mdl-38795134
ABSTRACT
The exploration of natural products as potential agents for cancer treatment has garnered significant attention in recent years. In this comprehensive review, we delve into the diverse array of natural compounds, including alkaloids, carbohydrates, flavonoids, lignans, polyketides, saponins, tannins, and terpenoids, highlighting their emerging roles in cancer therapy. These compounds, derived from various botanical sources, exhibit a wide range of mechanisms of action, targeting critical pathways involved in cancer progression such as cell proliferation, apoptosis, angiogenesis, and metastasis. Through a meticulous examination of preclinical and clinical studies, we provide insights into the therapeutic potential of these natural products across different cancer types. Furthermore, we discuss the advantages and challenges associated with their use in cancer treatment, emphasizing the need for further research to optimize their efficacy, pharmacokinetics, and delivery methods. Overall, this review underscores the importance of natural products in advancing cancer therapeutics and paves the way for future investigations into their clinical applications.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Produtos Biológicos
/
Neoplasias
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Arch Toxicol
/
Arch. toxicol
/
Archives of toxicology
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Índia