Sleep blood pressure measured using a home blood pressure monitor was independently associated with cardiovascular disease incidence: the Nagahama study.
J Hypertens
; 2024 May 28.
Article
em En
| MEDLINE
| ID: mdl-38842010
ABSTRACT
BACKGROUND:
Nocturnal blood pressure (BP) is associated with cardiovascular disease independently of awake BP. However, nocturnal BP measured using an ambulatory monitoring device has limited reproducibility because it is a single-day measurement. We investigated the association between sleep BP measured on multiple days using a timer-equipped home BP monitor and cardiovascular diseases in a general population.METHODS:
The study population comprised 5814 community residents. Participants were required to sleep with wrapping cuffs on their upper arm and BP was measured automatically at 0ââ00, 2ââ00, and 4ââ00. Actigraph was used to determine BP measured during sleep. Participants were also measured home morning and evening BP manually using the same device.RESULTS:
During the 7.3-year mean follow-up period, we observed 117 cases of cardiovascular diseases. The association between sleep BP (per 10âmmHg hazard ratioâ=â1.31, Pâ<â0.001) and cardiovascular events remained significant (hazard ratioâ=â1.22, Pâ=â0.036) even after adjusting for office BP and confounding factors, such as sleep-disordered breathing. Individuals with sleep-only hypertension (nâ=â1047; hazard ratioâ=â2.23, Pâ=â0.005) had a significant cardiovascular risk. Daytime-only hypertension (nâ=â264; hazard ratioâ=â3.57, Pâ=â0.001) and combined sleep and daytime hypertension (nâ=â1216; hazard ratioâ=â3.69, Pâ<â0.001) was associated with cardiovascular events to the same extent. Sleep BP dipping was not identified as a significant determinant of cardiovascular events.CONCLUSION:
Sleep BP measured using a home BP monitor was independently associated with the incidence of cardiovascular disease in a general population.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
J Hypertens
Ano de publicação:
2024
Tipo de documento:
Article