Three new diterpenoids from the roots of Euphorbia fischeriana and their cytotoxicity.
Fitoterapia
; 178: 106171, 2024 Oct.
Article
em En
| MEDLINE
| ID: mdl-39111719
ABSTRACT
Euphorbiabietane F (1), a novel abietane diterpenoid with the unprecedented 6/6/5/6/5 carbon skeleton, one new strobane diterpenoid (2), together with one new pimarane diterpenoid (3) were isolated from the roots of Euphorbia fischeriana. The structures were elucidated by the extensive spectroscopic data, gauge-independent atomic orbital (GIAO) NMR calculations, the comparison of experimental and calculated ECD spectra, as well as single crystal X-ray diffraction. The cytotoxicity result suggested the moderate inhibition rate of 1 on the cell lines of HepG2 and A549.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Raízes de Plantas
/
Euphorbia
/
Abietanos
/
Diterpenos
/
Compostos Fitoquímicos
/
Antineoplásicos Fitogênicos
Limite:
Humans
País/Região como assunto:
Asia
Idioma:
En
Revista:
Fitoterapia
Ano de publicação:
2024
Tipo de documento:
Article