A portal to highly valuable indole-functionalized vinyl sulfonyl fluorides and allylic sulfonyl fluorides.
Org Biomol Chem
; 22(35): 7117-7120, 2024 Sep 11.
Article
em En
| MEDLINE
| ID: mdl-39150283
ABSTRACT
A practical and efficient method for the C-3 site selective alkenylation of indoles was developed for constructing novel indole-functionalized vinyl sulfonyl fluorides and indolyl allylic sulfonyl fluorides. The reaction is accomplished with exclusive regio- and stereoselectivity without using transition metal catalysts, providing novel products of great potential value in medicinal chemistry, chemical biology, and drug discovery.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Org Biomol Chem
Assunto da revista:
BIOQUIMICA
/
QUIMICA
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
China