Viral and cellular DNA polymerase: comparison of activities with synthetic and natural RNA templates.
Science
; 176(4036): 798-800, 1972 May 19.
Article
em En
| MEDLINE
| ID: mdl-4113240
ABSTRACT
Two DNA polymerases purified from normal human lymphocytes are distinguishable from the viral reverse transcriptases of avian myeloblastosis virus and Mason-Pfizer monkey virus by their relative affinity for select templates. In this respect, the activity of the two normal human lymphocyte polymerases closely resembles the activity of Escherichia coli DNA polymerase 1. The viral and cellular DNA polymerases are equally active with the nonspecific template, poly(rA) . poly(dT). Criteria for distinguishing the activity of viral reverse transcriptase are discussed.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Moldes Genéticos
/
Vírus
/
RNA
/
Linfócitos
/
Vírus da Leucose Aviária
/
DNA Nucleotidiltransferases
/
Escherichia coli
Limite:
Humans
Idioma:
En
Revista:
Science
Ano de publicação:
1972
Tipo de documento:
Article