Avian pancreatic polypeptide phase shifts hamster circadian rhythms when microinjected into the suprachiasmatic region.
Science
; 223(4638): 833-5, 1984 Feb 24.
Article
em En
| MEDLINE
| ID: mdl-6546454
ABSTRACT
The suprachiasmatic nucleus has been identified tentatively as a circadian pacemaker. To examine the functional role of peptides found within suprachiasmatic neurons, avian pancreatic polypeptide and vasopressin were microinjected into the suprachiasmatic region. Avian pancreatic polypeptide, but not vasopressin, shifted the phase of the wheelrunning rhythm as a function of the time of its injection within the circadian cycle. Avian pancreatic polypeptide or a similar peptide may be one component of the neurochemical processes underlying entrainment to the light-dark cycle.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Núcleo Supraquiasmático
/
Polipeptídeo Pancreático
/
Ritmo Circadiano
Limite:
Animals
Idioma:
En
Revista:
Science
Ano de publicação:
1984
Tipo de documento:
Article