Identification of Thormählen-positive compound "B" in urine of patients with malignant melanoma.
Arch Dermatol Res
; 276(3): 156-9, 1984.
Article
em En
| MEDLINE
| ID: mdl-6548107
ABSTRACT
The identification of the entire structure of the Thormählen-positive compound B from melanotic urine is described. The compound was separated from other Thormählen-positive compounds using DEAE-cellulose column chromatography. On the basis of differential enzymic hydrolysis followed by gas chromatography-mass spectrometry analysis and comparison with synthetically prepared compounds it is possible to conclude that the Thormählen-positive compound B is a mixture of O-sulphate 5-hydroxy-6-methoxyindole and 6-hydroxy-5-methoxyindole with predominance of the latter.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Cutâneas
/
Indóis
/
Melaninas
/
Melanoma
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
En
Revista:
Arch Dermatol Res
Ano de publicação:
1984
Tipo de documento:
Article