Conjunctival ultrastructure in Niemann-Pick disease type C.
Am J Ophthalmol
; 90(5): 708-14, 1980 Nov.
Article
em En
| MEDLINE
| ID: mdl-7446653
ABSTRACT
A 5-year-old girl with Niemann-Pick disease type C had normal eyes but the conjunctival ultrastructure was abnormal. Lamellar cytoplasmic bodies, characteristic of Niemann-Pick disease, were found in epithelial cells, stromal fibroblasts, endothelial cells, and pericytes of the stromal capillaries. The basement membrane of the capillaries was multilayered. The Golgi apparatus was unusually well developed. The combination of ocular findings and conjunctival ultrastructure may be helpful in the differential diagnosis of Niemann-Pick disease and its subtypes.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doenças de Niemann-Pick
/
Túnica Conjuntiva
Tipo de estudo:
Diagnostic_studies
Limite:
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
/
Newborn
Idioma:
En
Revista:
Am J Ophthalmol
Ano de publicação:
1980
Tipo de documento:
Article