Histochemical changes of peripheral blood leukocytes during lithium treatment.
Bibl Psychiatr
; (160): 38-44, 1981.
Article
em En
| MEDLINE
| ID: mdl-7458883
ABSTRACT
The effect of lithium on the histochemistry of blood granulocytes was studied in 16 manic-depressive patients during lithium prophylaxis. Blood smears obtained before, at 2 months and at 12 months after initiation of treatment showed that lithium caused condensation of the chromatin in granulocytes, conformation changes in eosinophilic granules and the disappearance of basic proteins found in the cytoplasm of eosinophils in the drug-free patients. The latter findings are interpreted as indicating the involvement of lithium in histamine metabolism.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transtorno Bipolar
/
Leucócitos
/
Lítio
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Bibl Psychiatr
Ano de publicação:
1981
Tipo de documento:
Article