Difference in laminin expression between high and low metastatic cell clones derived from murine Lewis lung carcinoma.
Cell Struct Funct
; 18(3): 183-7, 1993 Jun.
Article
em En
| MEDLINE
| ID: mdl-8242796
ABSTRACT
We investigated the expression of laminin in two cell lines with different metastatic potentials established from murine Lewis lung carcinoma. Immunostaining of the cells with anti-laminin antibody and Northern blot analysis of laminin mRNA demonstrated that the high metastatic clone expressed less laminin than the low metastatic one. In contrast, expressions of 67 kDa-laminin receptor were at similar levels between these two lines. These findings show the possibility that endogenous laminin may contribute to the difference in metastatic properties in the murine Lewis lung carcinoma cell lines examined.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Laminina
/
Neoplasias Pulmonares
Limite:
Animals
Idioma:
En
Revista:
Cell Struct Funct
Ano de publicação:
1993
Tipo de documento:
Article
País de afiliação:
Japão