Seizures and hepatotoxicity following sulphasalazine administration.
Rheumatol Int
; 17(2): 75-7, 1997.
Article
em En
| MEDLINE
| ID: mdl-9266624
ABSTRACT
Sulphasalazine (SSZ) is a widely used second-line agent for several rheumatic diseases. Most of its side effects are relatively minor and dose dependent. We report a patient with juvenile onset chronic arthritis who developed hepatotoxicity and seizures on the third week of SSZ when the daily dose was increased to 2 g. Clinical and laboratory findings of liver and central nervous system toxicity gradually returned to normal in the month following SSZ withdrawal.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Artrite
/
Sulfassalazina
/
Convulsões
/
Antirreumáticos
/
Doença Hepática Induzida por Substâncias e Drogas
/
Fígado
Limite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
Rheumatol Int
Ano de publicação:
1997
Tipo de documento:
Article
País de afiliação:
Turquia