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1.
Acta Medica Philippina ; : 64-66, 2023.
Artigo em Inglês | WPRIM (Pacífico Ocidental) | ID: wpr-980497

RESUMO

@#Telangiectasia macularis eruptiva perstans (TMEP) is a rare disease, previously classified as a variant of cutaneous mastocytosis. While no gold standard of treatment exists, several treatments have been studied. We report a case of a 63-year-old woman who presented with long-standing asymptomatic telangiectatic macules beginning on the upper chest, back, and bilateral arms, with occasional pruritus and no other systemic symptoms. Skin biopsy, along with Giemsa stain, revealed findings consistent with TMEP. The patient underwent testing for serum tryptase level, which was within normal limits. The patient was started on topical steroids for two weeks and antihistamine therapy, with a noted decrease in pruritus but no change in cutaneous lesions. She was then advised to start phototherapy, and subsequently underwent a total of five sessions of narrow-band ultraviolet B phototherapy, after which she noted lightening of the lesions. Due to the COVID pandemic, the patient was shifted to heliotherapy with continued lightening of lesions after two months of thrice weekly sessions. This rare case is supportive of narrow-band ultraviolet B phototherapy and heliotherapy as promising treatment options for cases of TMEP.


Assuntos
Mastocitose , Fototerapia , Helioterapia
3.
Comput Biol Chem ; 96: 107602, 2022 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-34823125

RESUMO

Herein it is proposed that sufficient exposure to sunlight (UVB) modulates host gene expression, offering protection against severe consequences of COVID-19. This could be in addition to sunlight (UVB)-mediated protection by directly inactivating the virus and limiting the viral load. It is suggested that inhibition of CCR2, DPP9, HSPA1L, IFNAR2, OAS1, and TYK2 may, in part, explain UVB-mediated protection against severe consequences of COVID-19.


Assuntos
COVID-19/prevenção & controle , SARS-CoV-2 , Luz Solar , COVID-19/genética , COVID-19/terapia , Biologia Computacional , Expressão Gênica/efeitos da radiação , Perfilação da Expressão Gênica , Helioterapia , Humanos , Modelos Biológicos , Índice de Gravidade de Doença , Raios Ultravioleta
4.
Cochrane Database Syst Rev ; 7: CD013277, 2021 07 06.
Artigo em Inglês | MEDLINE | ID: mdl-34228352

RESUMO

BACKGROUND: Acute bilirubin encephalopathy (ABE) and the other serious complications of severe hyperbilirubinemia in the neonate occur far more frequently in low- and middle-income countries (LMIC). This is due to several factors that place babies in LMIC at greater risk for hyperbilirubinemia, including increased prevalence of hematologic disorders leading to hemolysis, increased sepsis, less prenatal or postnatal care, and a lack of resources to treat jaundiced babies. Hospitals and clinics face frequent shortages of functioning phototherapy machines and inconsistent access to electricity to run the machines. Sunlight has the potential to treat hyperbilirubinemia: it contains the wavelengths of light that are produced by phototherapy machines. However, it contains harmful ultraviolet light and infrared radiation, and prolonged exposure has the potential to lead to sunburn, skin damage, and hyperthermia or hypothermia. OBJECTIVES: To evaluate the efficacy of sunlight administered alone or with filtering or amplifying devices for the prevention and treatment of clinical jaundice or laboratory-diagnosed hyperbilirubinemia in term and late preterm neonates. SEARCH METHODS: We used the standard search strategy of Cochrane Neonatal to search CENTRAL (2019, Issue 5), MEDLINE, Embase, and CINAHL on 2 May 2019. We also searched clinical trials databases, conference proceedings, and the reference lists of retrieved articles for randomized controlled trials (RCTs), quasi-RCTs, and cluster RCTs. We updated the searches on 1 June 2020. SELECTION CRITERIA: We included RCTs, quasi-RCTs, and cluster RCTs. We excluded crossover RCTs. Included studies must have evaluated sunlight (with or without filters or amplification) for the prevention and treatment of hyperbilirubinemia or jaundice in term or late preterm neonates. Neonates must have been enrolled in the study by one-week postnatal age. DATA COLLECTION AND ANALYSIS: We used standard methodologic procedures expected by Cochrane. We used the GRADE approach to assess the certainty of evidence. Our primary outcomes were: use of conventional phototherapy, treatment failure requiring exchange transfusion, ABE, chronic bilirubin encephalopathy, and death. MAIN RESULTS: We included three RCTs (1103 infants). All three studies had small sample sizes, were unblinded, and were at high risk of bias. We planned to undertake four comparisons, but only found studies reporting on two. Sunlight with or without filters or amplification compared to no treatment for the prevention and treatment of hyperbilirubinemia in term and late preterm neonates One study of twice-daily sunlight exposure (30 to 60 minutes) compared to no treatment reported the incidence of jaundice may be reduced (risk ratio [RR] 0.61, 95% confidence interval [CI] 0.45 to 0.82; risk difference [RD] -0.14, 95% CI -0.22 to -0.06; number needed to treat for an additional beneficial outcome [NNTB] 7, 95% CI 5 to 17; 1 study, 482 infants; very low-certainty evidence) and the number of days that an infant was jaundiced may be reduced (mean difference [MD] -2.20 days, 95% CI -2.60 to -1.80; 1 study, 482 infants; very low-certainty evidence). There were no data on safety or potential harmful effects of the intervention. The study did not assess use of conventional phototherapy, treatment failure requiring exchange transfusion, ABE, and long-term consequences of hyperbilirubinemia. The study showed that sunlight therapy may reduce rehospitalization rates within seven days of discharge for treatment for hyperbilirubinemia, but the evidence was very uncertain (RR 0.55, 95% CI 0.27 to 1.11; RD -0.04, -0.08 to 0.01; 1 study, 482 infants; very low-certainty evidence). Sunlight with or without filters or amplification compared to other sources of phototherapy for the treatment of hyperbilirubinemia in infants with confirmed hyperbilirubinemia Two studies (621 infants) compared the effect of filtered-sunlight exposure to other sources of phototherapy in infants with confirmed hyperbilirubinemia. Filtered-sunlight phototherapy (FSPT) and conventional or intensive electric phototherapy led to a similar number of days of effective treatment (broadly defined as a minimal increase of total serum bilirubin in infants less than 72 hours old and a decrease in total serum bilirubin in infants more than 72 hours old on any day that at least four to five hours of sunlight therapy was available). There may be little or no difference in treatment failure requiring exchange transfusion (typical RR 1.00, 95% CI 0.06 to 15.73; typical RD 0.00, 95% CI -0.01 to 0.01; 2 studies, 621 infants; low-certainty evidence). One study reported ABE, and no infants developed this outcome (RR not estimable; RD 0.00, 95% CI -0.02 to 0.02; 1 study, 174 infants; low-certainty evidence). One study reported death as a reason for study withdrawal; no infants were withdrawn due to death (RR not estimable; typical RD 0.00, 95% CI -0.01 to 0.01; 1 study, 447 infants; low-certainty evidence). Neither study assessed long-term outcomes. Possible harms: both studies showed a probable increased risk for hyperthermia (body temperature greater than 37.5 °C) with FSPT (typical RR 4.39, 95% CI 2.98 to 6.47; typical RD 0.30, 95% CI 0.23 to 0.36; number needed to treat for an additional harmful outcome [NNTH] 3, 95% CI 2 to 4; 2 studies, 621 infants; moderate-certainty evidence). There was probably no difference in hypothermia (body temperature less than 35.5 °C) (typical RR 1.06, 95% CI 0.55 to 2.03; typical RD 0.00, 95% CI -0.03 to 0.04; 2 studies, 621 infants; moderate-certainty evidence). AUTHORS' CONCLUSIONS: Sunlight may be an effective adjunct to conventional phototherapy in LMIC settings, may allow for rotational use of limited phototherapy machines, and may be preferable to families as it can allow for increased bonding. Filtration of sunlight to block harmful ultraviolet light and frequent temperature checks for babies under sunlight may be warranted for safety. Sunlight may be effective in preventing hyperbilirubinemia in some cases, but these studies have not demonstrated that sunlight alone is effective for the treatment of hyperbilirubinemia given its sporadic availability and the low or very low certainty of the evidence in these studies.


Assuntos
Helioterapia/métodos , Hiperbilirrubinemia Neonatal/terapia , Viés , Transfusão Total , Helioterapia/efeitos adversos , Helioterapia/instrumentação , Humanos , Hiperbilirrubinemia Neonatal/epidemiologia , Hiperbilirrubinemia Neonatal/prevenção & controle , Hipertermia/epidemiologia , Hipotermia/epidemiologia , Incidência , Recém-Nascido , Recém-Nascido Prematuro , Icterícia Neonatal/prevenção & controle , Icterícia Neonatal/terapia , Readmissão do Paciente/estatística & dados numéricos , Ensaios Clínicos Controlados Aleatórios como Assunto , Falha de Tratamento
5.
Sci Rep ; 11(1): 5031, 2021 03 03.
Artigo em Inglês | MEDLINE | ID: mdl-33658568

RESUMO

Exposure to appropriate doses of UV radiation provides enormously health and medical treatment benefits including psoriasis. Typical hospital-based phototherapy cabinets contain a bunch of artificial lamps, either broad-band (main emission spectrum 280-360 nm, maximum 320 nm), or narrow-band UV B irradiation (main emission spectrum 310-315 nm, maximum 311 nm). For patients who cannot access phototherapy centers, sunbathing, or heliotherapy, can be a safe and effective treatment alternative. However, as sunlight contains the full range of UV radiation (290-400 nm), careful sunbathing supervised by photodermatologist based on accurate UV radiation forecast is vital to minimize potential adverse effects. Here, using 10-year UV radiation data collected at Nakhon Pathom, Thailand, we developed a deep learning model for UV radiation prediction which achieves around 10% error for 24-h forecast and 13-16% error for 7-day up to 4-week forecast. Our approach can be extended to UV data from different geographical regions as well as various biological action spectra. This will become one of the key tools for developing national heliotherapy protocol in Thailand. Our model has been made available at https://github.com/cmb-chula/SurfUVNet .


Assuntos
Aprendizado Profundo , Helioterapia/métodos , Psoríase/radioterapia , Doses de Radiação , Terapia Ultravioleta/métodos , Benchmarking , Conjuntos de Dados como Assunto , Humanos , Radiometria , Luz Solar , Raios Ultravioleta
6.
Artigo em Russo | MEDLINE | ID: mdl-33307664

RESUMO

OBJECTIVE: Scientometrical analysis of studies the use of climatotherapy methods and formulation of guidelines based on the evidence obtained during the analysis. MATERIAL AND METHODS: The article presents the data of scientometrical analysis of 40 publications on the use of climatotherapy in spa practice. RESULTS: Clinical effects and proposed mechanisms of action of the proven efficacy climatotherapy methods - aerotherapy, heliotherapy and thalassotherapy for the patients with various chronic diseases are presented. The clinical directions for the using of climatotherapy methods in climatic resorts are highlighted. CONCLUSIONS: Regular generalization and analysis of existing evidence-based studies is required, as well as the implementation of new high-quality randomized controlled clinical trials to study the effects of climate therapy on a wide range of patients with common socially significant diseases.


Assuntos
Climatoterapia , Doença Crônica , Estâncias para Tratamento de Saúde , Helioterapia , Humanos , Modalidades de Fisioterapia
7.
SEMERGEN, Soc. Esp. Med. Rural Gen. (Ed. Impr.) ; 46(6): 406-410, sept. 2020. ilus, tab, graf
Artigo em Espanhol | IBECS | ID: ibc-200413

RESUMO

La vitamina D es una vitamina liposoluble cuya principal función en el organismo es la regulación del metabolismo calcio-fósforo. El receptor de la vitamina D está presente en la mayoría de las células nucleadas de nuestro organismo, por lo que se está descubriendo su intervención en múltiples procesos. Las 3 principales fuentes para su obtención son la radiación ultravioleta, la alimentación y la suplementación. La piel, a través de la radiación solar, proporciona el 90% de la vitamina D que necesitamos. En casos deficitarios se han de repasar los hábitos de exposición solar, alimentación y se ha de valorar la suplementación farmacológica. La medición en el organismo se realiza mediante la determinación de 25-hidroxicolecalciferol y valores por debajo de 20ng/ml se consideran inadecuados. En el momento actual no se recomienda el cribado universal de vitamina D, sino en aquellos casos en los que se sospeche un déficit


Vitamin D is a fat-soluble vitamin which has the regulation of calcium-phosphorus metabolism in the body as its main function. Vitamin D receptor is present in most of the nucleated cells of the body, and its role in multiple body processes is being discovered. The 3 main sources of vitamin D are ultraviolet sun radiation, diet, and supplementation. The skin, through solar radiation, provides 90% of the bodýs vitamin D needs. In cases of low vitamin D, sun exposure habits and diet must be reviewed, and pharmacological supplementation must be assessed. Measurement in the body is performed by determining 25-hydroxycholecalciferol with values below 20ng/ml being considered insufficient. Universal screening of vitamin D is not currently recommended, only in situations where a deficiency is suspected


Assuntos
Humanos , Vitamina D/análise , Colecalciferol/administração & dosagem , Deficiência de Vitamina D/tratamento farmacológico , Helioterapia/métodos , Osteoporose/epidemiologia , Raquitismo/epidemiologia , Osteomalacia/epidemiologia , Deficiência de Vitamina D/epidemiologia , Luz Solar , Terapia Ultravioleta/métodos , Fatores de Risco
9.
J Photochem Photobiol B ; 207: 111891, 2020 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-32388486

RESUMO

The recent outbreak of COVID-19, which continues to ravage communities with high death tolls and untold psychosocial and catastrophic economic consequences, is a vivid reminder of nature's capacity to defy contemporary healthcare. The pandemic calls for rapid mobilization of every potential clinical tool, including phototherapy-one of the most effective treatments used to reduce the impact of the 1918 "Spanish influenza" pandemic. This paper cites several studies showing that phototherapy has immense potential to reduce the impact of coronavirus diseases, and offers suggested ways that the healthcare industry can integrate modern light technologies in the fight against COVID-19 and other infections. The evidence shows that violet/blue (400-470 nm) light is antimicrobial against numerous bacteria, and that it accounts for Niels Ryberg Finsen's Nobel-winning treatment of tuberculosis. Further evidence shows that blue light inactivates several viruses, including the common flu coronavirus, and that in experimental animals, red and near infrared light reduce respiratory disorders, similar to those complications associated with coronavirus infection. Moreover, in patients, red light has been shown to alleviate chronic obstructive lung disease and bronchial asthma. These findings call for urgent efforts to further explore the clinical value of light, and not wait for another pandemic to serve as a reminder. The ubiquity of inexpensive light emitting lasers and light emitting diodes (LEDs), makes it relatively easy to develop safe low-cost light-based devices with the potential to reduce infections, sanitize equipment, hospital facilities, emergency care vehicles, homes, and the general environment as pilot studies have shown.


Assuntos
Infecções por Coronavirus/terapia , Fototerapia , COVID-19 , Infecções por Coronavirus/epidemiologia , Infecções por Coronavirus/virologia , Helioterapia , Humanos , Raios Infravermelhos , Luz , Terapia com Luz de Baixa Intensidade , Pneumopatias/epidemiologia , Pneumopatias/terapia , Pneumopatias/virologia , Pandemias , Fototerapia/métodos , Pneumonia Viral
10.
Int J Biometeorol ; 64(7): 1145-1152, 2020 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-32133542

RESUMO

This study assessed the effects of liman peloid, followed by bath and heliotherapy in psoriatic patients at Cervia, Emilia, Italy. The psoriatic patients were randomized into two groups: group 1 with 56 patients, treated with liman applications, bath, and heliotherapy, and group 2 with 35 subjects, treated with mud-bath therapy using a clay peloid mixed with tap water and heliotherapy. Data was collected for the following: psoriasis area and severity index (PASI); delta-PASI (difference between post- and pre-treatment PASI); delta-PASI3 and delta-PASI6, 3 and 6 months after the end of treatment, respectively; psoriasis recurrences; and the use of both topical and systemic drugs. Although not significant, a decrease in PASI was recorded in group 1 at the end of treatment and after 3 and 6 months. Compared with group 2, there was a significant change in delta-PASI, delta-PASI3, and psoriasis recurrences in group 1 as well as a significant reduction in the topical use of drugs, both cortisone and nonsteroid drugs. This is the first and preliminary study which documented the efficacy of a specific protocol of liman bath heliotherapy in psoriatic patients as documented by a reduction in delta-PASI and delta-PASI3, a decrease in psoriasis recurrences, and use of topical drugs.


Assuntos
Helioterapia , Psoríase , Banhos , Humanos , Itália , Índice de Gravidade de Doença , Resultado do Tratamento
11.
Pediatr Dermatol ; 36(5): 690-692, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31313355

RESUMO

Lichen nitidus is a benign inflammatory dermatosis that typically presents in a localized distribution. We present the rare case of a 6-year-old boy with a 1-year history of generalized lichen nitidus with limited access to narrowband ultraviolet B phototherapy. Over the course of a summer, he had complete and lasting resolution of generalized lichen nitidus after daily natural sunlight exposure. This case demonstrates a rare variant of lichen nitidus and a practical treatment alternative to in-office phototherapy.


Assuntos
Helioterapia , Líquen Nítido/terapia , Criança , Humanos , Masculino
13.
Int J Dermatol ; 58(4): 472-476, 2019 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-30506679

RESUMO

BACKGROUND: Noncultured epidermal cell suspension (NCES) is an effective surgical modality for stable vitiligo which involves transplantation of the basal layer of epidermal cells onto the dermabraded vitiliginous patch. Platelet-rich plasma (PRP) has growth factors which may stimulate melanocyte migration and proliferation of keratinocytes and fibroblasts. The objective of this study was to compare the extent of repigmentation achieved by transplantation of NCES suspended in PRP with that of NCES suspended in phosphate buffered saline (PBS). METHODS: Twenty-one patients of stable vitiligo with at least two lesions of comparable size were included. The two vitiligo patches were randomized to receive NCES suspended in PRP or PBS. Postoperatively after 1 week, patients were given heliotherapy for 15 minutes daily. RESULTS: At 6 months follow-up, mean repigmentation by area method in PRP arm was 75.6 ± 30% SD and in non-PRP arm was 65 ± 34% SD (P = 0.0036). Patient satisfaction by visual analogue scale at 6 months also showed better results in PRP arm (P = 0.001). Assessment by three independent observers showed better repigmentation in PRP side both at 3 and 6 months. CONCLUSIONS: Suspending NCES in PRP can result in significantly greater mean repigmentation and patient satisfaction than suspending in PBS.


Assuntos
Células Epidérmicas/transplante , Plasma Rico em Plaquetas , Pigmentação da Pele , Vitiligo/terapia , Adolescente , Adulto , Método Duplo-Cego , Feminino , Helioterapia , Humanos , Masculino , Satisfação do Paciente , Solução Salina , Transplante Autólogo/métodos , Resultado do Tratamento , Adulto Jovem
15.
Acta Derm Venereol ; 98(2): 256-261, 2018 Feb 07.
Artigo em Inglês | MEDLINE | ID: mdl-28815268

RESUMO

Dead Sea climatotherapy (DSC) is a therapeutic modality for a variety of chronic skin conditions, yet there has been scarce research on the relationship between the cutaneous microbiota and disease states in response to DSC. We characterized the skin bacterial and fungal microbiome of healthy volunteers who underwent DSC. Bacterial community diversity remained similar before and after treatment, while fungal diversity was significantly reduced as a result of the treatment. Individuals showed greater inter-individual than temporal bacterial community variance, yet the opposite was true for fungal community composition. We further identified Malassezia as the genus driving temporal mycobiome variations. The results indicate that the microbiome remains stable throughout DSC, while the mycobiome undergoes dramatic community changes. The results of this study will serve as an important baseline for future investigations of microbiome and mycobiome temporal phenomena in diseased states.


Assuntos
Bactérias/crescimento & desenvolvimento , Balneologia/métodos , Climatoterapia/métodos , Fungos/crescimento & desenvolvimento , Helioterapia/métodos , Microbiota , Pele/microbiologia , Bactérias/classificação , Feminino , Fungos/classificação , Voluntários Saudáveis , Humanos , Israel , Malassezia/crescimento & desenvolvimento , Masculino , Micobioma , Fatores de Tempo
16.
Licere (Online) ; 20(4): 107-128, dez.2017.
Artigo em Português | LILACS | ID: biblio-880116

RESUMO

Neste ensaio refletimos sobre o corpo e sua aparência, considerando-se o contato com o sol, as práticas de proteção solar e as técnicas de bronzeamento. De um lado, os investimentos em torno da proteção contra os raios ultravioletas, não apenas com a proteção de cremes solares, mas de roupas que prometem proteção de 98% da superfície coberta. De outro lado, o bronzeamento natural feito na praia ou em clínicas especializadas. Essas técnicas e práticas aportam elementos para nossa reflexão sobre a ecologia corporal ao nos permitir pensar a respeito da relação entre o corpo íntimo e social, as aparências, o desejo, as significações sociais construídas pela medicina, cosmetologia e pelo lazer.


In this paper we reflect on the body and its appearance, considering the contact with the sun and the tanning and protection practices. On the one hand, investments around protection against ultraviolet rays, not only with the protection of solar creams, but with clothes that promise protection of 98% of the surface covered. On the other hand, the natural tanning done in specialized clinics. These practices provide elements for our reflection on body ecology by allowing us to think about the relationship between the intimate and social body, appearances, desire, social meanings built by medicine, cosmetology and leisure.


Assuntos
Neoplasias Cutâneas , Protetores Solares , Saúde , Fatores de Risco , Câmaras de Bronzeamento , Banho de Sol , Hidratação , Helioterapia
17.
Early Hum Dev ; 114: 11-15, 2017 11.
Artigo em Inglês | MEDLINE | ID: mdl-28919246

RESUMO

Challenges in treating severe neonatal jaundice in low and middle-income country settings still exist at many levels. These include: a lack of awareness of causes and prevention by families, communities and even sometimes health care professionals; insufficient, ineffective, high quality affordable diagnostic and therapeutic options; limited availability of rehabilitation provision for kernicterus. Collectively these challenges lead to an unacceptably high global morbidity and mortality from severe neonatal jaundice. In the past decade, there has been an explosion of innovations addressing some of these issues and these are increasingly available for scale up. Scientists, healthcare providers, and communities are joining hands to explore educational tools, low cost screening and diagnostic options including at point-of-care and treatment modalities including filtered sunlight and solar powered phototherapy. For the first time, the possibility of eliminating the tragedy of preventable morbidity and mortality from severe NNJ is on the horizon, for all.


Assuntos
Helioterapia/métodos , Icterícia Neonatal/prevenção & controle , Fototerapia/métodos , Países em Desenvolvimento , Feminino , Helioterapia/economia , Humanos , Recém-Nascido , Icterícia Neonatal/diagnóstico , Icterícia Neonatal/epidemiologia , Icterícia Neonatal/terapia , Fototerapia/economia
19.
Acta Derm Venereol ; 97(8): 934-940, 2017 Aug 31.
Artigo em Inglês | MEDLINE | ID: mdl-28536730

RESUMO

Alexithymia, defined as difficulty in describing or recognizing emotions, has been shown to be connected with psoriasis, but its relationship with self-management of psoriasis has not been explored. The aim of this study was to assess the frequency of alexithymia and its relationship with self-management and illness perception in the context of psoriasis. A total of 163 patients participating in 3 weeks of climate heliotherapy (CHT) at Gran Canaria were assessed for alexithymia using the Toronto Alexithymia Scale (TAS-20) at baseline. Self-reported measures for self-management (Health Education Impact Questionnaire; heiQ), and disease severity and illness perception (Brief Illness Perception Questionnaire; BIPQ) were assessed twice. Of all patients, 14.1% were characterized as alexithymic and 22.1% scored in the intermediate range. Alexithymic patients scored significantly worse in all heiQ domains, and reported worse illness perception. However, there were no between-group differences in heiQ or BIPQ change from baseline to after CHT. In conclusion, this study shows that alexithymia indicates inferior self-management and reaffirms the associations with illness perception. Further research is required into these relationships.


Assuntos
Sintomas Afetivos/psicologia , Sintomas Afetivos/terapia , Helioterapia , Entrevista Motivacional , Psoríase/psicologia , Psoríase/terapia , Autocuidado/métodos , Autoimagem , Adulto , Sintomas Afetivos/diagnóstico , Idoso , Efeitos Psicossociais da Doença , Feminino , Conhecimentos, Atitudes e Prática em Saúde , Humanos , Masculino , Pessoa de Meia-Idade , Medidas de Resultados Relatados pelo Paciente , Psoríase/diagnóstico , Qualidade de Vida , Autorrelato , Índice de Gravidade de Doença , Suécia , Fatores de Tempo , Resultado do Tratamento , Adulto Jovem
20.
Photochem Photobiol Sci ; 16(3): 416-425, 2017 Mar 16.
Artigo em Inglês | MEDLINE | ID: mdl-28102417

RESUMO

The Ultraviolet (UV) radiation contained in sunlight is a powerful mutagen and immune suppressant which partly explains why exposure to solar UV is the biggest risk factor for the development of cutaneous tumours. Evidence is building that sunlight may be protective against some internal malignancies. Because patients with these tumours are often vitamin D deficient, this has led some to propose that vitamin D supplementation will be beneficial in the treatment of these cancers. However, the results from already completed trials have been disappointing which has given weight to the argument that there must be something else about sunlight that explains its cancer-protecting properties.


Assuntos
Helioterapia , Neoplasias Cutâneas/terapia , Luz Solar , Deficiência de Vitamina D/tratamento farmacológico , Vitamina D/uso terapêutico , Suplementos Nutricionais , Humanos , Neoplasias Cutâneas/complicações , Falha de Tratamento , Vitamina D/administração & dosagem , Deficiência de Vitamina D/complicações
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