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1.
Radiología (Madr., Ed. impr.) ; 66(2): 121-131, Mar.- Abr. 2024. graf, tab, ilus, mapas
Artigo em Espanhol | IBECS | ID: ibc-231514

RESUMO

Introducción: Existen desigualdades por razón de género en todos los ámbitos, incluyendo la radiología. Aunque la situación está mejorando, la presencia de radiólogas en puestos de liderazgo continúa siendo minoritaria. El objetivo de este artículo es analizar la situación de la mujer en la radiología española, comparándola con Europa y EE. UU. Materiales y métodos: Seleccionamos como franja de referencia los años 2000-2022 para hacer una comparación con datos de feminización a lo largo de la historia. Además también se incluyeron datos puntuales relevantes del recién comenzado 2023. Las variables en las que investigamos la feminización fueron las siguientes: estudiantes de medicina, médicos graduados, residentes y especialistas en radiodiagnóstico, jefes de sección, jefes de servicio, tutores de residentes de radiodiagnóstico, radiólogos profesores universitarios, presidentes de las principales entidades y sociedades radiológicas de España, Europa y EE. UU., receptores de los principales galardones de dichas sociedades radiológicas y editores jefe de sus revistas. Para ello realizamos una amplia búsqueda bibliográfica, contactamos con las sociedades radiológicas de España, Europa y EE. UU. y realizamos una encuesta a los principales servicios de radiodiagnóstico de España. Resultados: La presencia femenina en radiología va disminuyendo a medida que ascendemos a puestos de liderazgo, situación que se constata tanto en España como en Europa y EE. UU., comparativa que analizaremos en profundidad a lo largo del artículo. En los hospitales españoles en el año 2021 había un 58,1% de mujeres residentes de radiodiagnóstico, 55% de radiólogas, 42,9% de jefas de sección y 24,4% de jefas de servicio. En la historia de la SERAM ha habido un 10% de mujeres presidentas, un 22% de mujeres medallas de oro y un 5% de editoras jefe. Analizando los datos del año 2000 al 2023 el porcentaje de presidentas alcanza el 32% y las mujeres medalla de oro el 31%.(AU)


Introduction: There are gender inequalities in all fields, including radiology. Although the situation is improving, the presence of radiologists in leadership positions continues to be a minority. The objective of this article is to analyze the situation of women in the spanish radiology, comparing it with Europe and the United States. Materials and methods: We selected the years 2000-2022 as reference period to make a comparison with feminization data throughout history. In addition, relevant specific data from the just begun 2023 were also included. The variables in which we investigated feminization were the following: medical students, medical graduates, radiology residents and specialists, section chiefs, department chairs, radiology residency programme directors, radiology university professors, presidents of the main radiological entities and societies in Spain, Europe and the United States, recipients of the main awards given by these radiological societies and chief editors of their journals. In order to perform this analysis we conducted an in-depth bibliographic research, we contacted the radiological societies of Spain, Europe and the USA and we carried out a survey in the main spanish radiology departments. Results: The female presence in radiology decreases as we rise to leadership positions, a situation that is patent in Spain, Europe and the US, comparison that will be analyzed in depth throughout the article. In spanish hospitals in 2021 there were 58.1% female radiology residents, 55% female radiologists, 42.9% female section chiefs and 24.4% female department chairs. In SERAM's history there have been 10% female presidents, 22% female gold medallists and 5% female editors-in-chief. If we analyze data from 2000 to 2023, female presidents reach 32% and female gold medallists 31%.(AU)


Assuntos
Humanos , Feminino , Sexismo , 57444 , Liderança , Feminização , Radiologia , Espanha
2.
FASEB J ; 38(6): e23552, 2024 Mar 31.
Artigo em Inglês | MEDLINE | ID: mdl-38498336

RESUMO

Sex and gender disparities in biomedical research have been emphasized to improve scientific knowledge applied for the health of both men and women. Despite sex differences in cancer incidence, prognosis, and responses to therapeutic agents, mechanistic explanations at molecular levels are far from enough. Recent studies suggested that cell sex is an important biological variable due to differences in sex chromosome gene expression and differences in events associated with developmental biology. The objective of this study was to analyze the reporting of sex of cells used in cancer research using articles published in Cancer Cell, Molecular Cancer, Journal of Hematology & Oncology, Journal for ImmunoTherapy of Cancer, and Cancer Research in 2020, and to examine whether there exists any sex bias. We found that the percentage of cells with sex notation in the article was 36.5%. Primary cells exhibited higher sex notation compared to cell lines. A higher percentage of female cells were used in cell cultures with sex notation. Also, sex-common cells omitted sex description more often compared to sex-specific cells. None of the cells isolated from embryo and esophagus reported the cell sex in the article. Our results indicate cell sex report in cancer research is limited to a small proportion of cells used in the study. These results call for acknowledging the sex of cells to increase the applicability of biomedical research discoveries.


Assuntos
Pesquisa Biomédica , Células Cultivadas , Neoplasias , Feminino , Humanos , Masculino , Publicações , Fatores Sexuais , Sexismo
3.
Sci Rep ; 14(1): 5224, 2024 03 04.
Artigo em Inglês | MEDLINE | ID: mdl-38433238

RESUMO

Large language models (LLMs) have the potential to transform our lives and work through the content they generate, known as AI-Generated Content (AIGC). To harness this transformation, we need to understand the limitations of LLMs. Here, we investigate the bias of AIGC produced by seven representative LLMs, including ChatGPT and LLaMA. We collect news articles from The New York Times and Reuters, both known for their dedication to provide unbiased news. We then apply each examined LLM to generate news content with headlines of these news articles as prompts, and evaluate the gender and racial biases of the AIGC produced by the LLM by comparing the AIGC and the original news articles. We further analyze the gender bias of each LLM under biased prompts by adding gender-biased messages to prompts constructed from these news headlines. Our study reveals that the AIGC produced by each examined LLM demonstrates substantial gender and racial biases. Moreover, the AIGC generated by each LLM exhibits notable discrimination against females and individuals of the Black race. Among the LLMs, the AIGC generated by ChatGPT demonstrates the lowest level of bias, and ChatGPT is the sole model capable of declining content generation when provided with biased prompts.


Assuntos
Insuficiência da Valva Aórtica , Camelídeos Americanos , Humanos , Feminino , Masculino , Animais , Sexismo , Viés , Idioma
4.
PLoS One ; 19(3): e0299381, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38507365

RESUMO

BACKGROUND: Emerging evidence suggests that perceived gender discrimination negatively impacts mental wellbeing in young women. PURPOSE: This study explored whether a similar relationship exists in middle-aged and older women. METHODS: A total of 3081 women (aged ≥52 years) from the English Longitudinal Study of Ageing provided data on perceived gender discrimination in 2010/11. Depressive symptoms, loneliness, quality of life and life satisfaction were assessed in 2010/11 and in 2016/17. RESULTS: Perceived gender discrimination was reported by 282 (9.2%) participants. Cross-sectionally, women who perceived gender discrimination reported more depressive symptoms (ß = 0.34, 95% CI 0.11 to 0.57) and had higher loneliness scores (ß = 0.14, 95% CI 0.08 to 0.20) than women who did not perceive gender discrimination. They also reported significantly lower quality of life (ß = -2.50, 95% CI -3.49 to -1.51) and life satisfaction (ß = -1.07, 95% CI -1.81 to -0.33). Prospectively, perceived gender discrimination was associated with greater loneliness scores (ß = 0.08, 95% CI 0.02 to 0.14), as well as lower ratings of quality of life (ß = -0.98, 95% CI -0.09 to -1.86), and life satisfaction (ß = -1.04, 95% CI -0.34 to -1.74), independent of baseline values. CONCLUSIONS: Middle-aged and older women who perceive gender discrimination report poorer mental wellbeing than those who do not perceive discrimination. Further, this type of discrimination may be predictive of declining mental wellbeing over time. These findings highlight the need for interventions to target gender-based discrimination to improve the wellbeing of women at mid- and older age.


Assuntos
Qualidade de Vida , Sexismo , Pessoa de Meia-Idade , Humanos , Feminino , Idoso , Estudos Longitudinais , Solidão , Envelhecimento
5.
J Med Internet Res ; 26: e51837, 2024 Mar 05.
Artigo em Inglês | MEDLINE | ID: mdl-38441945

RESUMO

BACKGROUND: Artificial intelligence chatbots such as ChatGPT (OpenAI) have garnered excitement about their potential for delegating writing tasks ordinarily performed by humans. Many of these tasks (eg, writing recommendation letters) have social and professional ramifications, making the potential social biases in ChatGPT's underlying language model a serious concern. OBJECTIVE: Three preregistered studies used the text analysis program Linguistic Inquiry and Word Count to investigate gender bias in recommendation letters written by ChatGPT in human-use sessions (N=1400 total letters). METHODS: We conducted analyses using 22 existing Linguistic Inquiry and Word Count dictionaries, as well as 6 newly created dictionaries based on systematic reviews of gender bias in recommendation letters, to compare recommendation letters generated for the 200 most historically popular "male" and "female" names in the United States. Study 1 used 3 different letter-writing prompts intended to accentuate professional accomplishments associated with male stereotypes, female stereotypes, or neither. Study 2 examined whether lengthening each of the 3 prompts while holding the between-prompt word count constant modified the extent of bias. Study 3 examined the variability within letters generated for the same name and prompts. We hypothesized that when prompted with gender-stereotyped professional accomplishments, ChatGPT would evidence gender-based language differences replicating those found in systematic reviews of human-written recommendation letters (eg, more affiliative, social, and communal language for female names; more agentic and skill-based language for male names). RESULTS: Significant differences in language between letters generated for female versus male names were observed across all prompts, including the prompt hypothesized to be neutral, and across nearly all language categories tested. Historically female names received significantly more social referents (5/6, 83% of prompts), communal or doubt-raising language (4/6, 67% of prompts), personal pronouns (4/6, 67% of prompts), and clout language (5/6, 83% of prompts). Contradicting the study hypotheses, some gender differences (eg, achievement language and agentic language) were significant in both the hypothesized and nonhypothesized directions, depending on the prompt. Heteroscedasticity between male and female names was observed in multiple linguistic categories, with greater variance for historically female names than for historically male names. CONCLUSIONS: ChatGPT reproduces many gender-based language biases that have been reliably identified in investigations of human-written reference letters, although these differences vary across prompts and language categories. Caution should be taken when using ChatGPT for tasks that have social consequences, such as reference letter writing. The methods developed in this study may be useful for ongoing bias testing among progressive generations of chatbots across a range of real-world scenarios. TRIAL REGISTRATION: OSF Registries osf.io/ztv96; https://osf.io/ztv96.


Assuntos
Inteligência Artificial , Sexismo , Humanos , Feminino , Masculino , Revisões Sistemáticas como Assunto , Idioma , Linguística
9.
Sci Rep ; 14(1): 5733, 2024 03 08.
Artigo em Inglês | MEDLINE | ID: mdl-38459178

RESUMO

Gender is a key determinant of health and healthcare use. The question of whether physicians are aware of gender issues is important to avoid gender bias in medical practice. This study aimed to validate the Nijmegen Gender Awareness in Medicine Scale (N-GAMS) in a representative population of French general practitioners (GPs) and to analyze their gender sensitivity and the presence of gender stereotypes among them. The N-GAMS, already validated in medical students, measures gender awareness through 3 subscores: gender sensitivity (GS) and gender-role ideology towards patients (GRIP) and doctors (GRID) (gender stereotypes). After translation into French, it was distributed to 900 GPs. The scale was validated through exploratory factor analysis (EFA). Psychometric properties were tested. Multivariate linear regressions were conducted to explore the associations between GPs' characteristics and N-GAMS subscores. EFA identified 3 meaningful factors consistent with prior theory. Subscores exhibited good internal consistency. The main findings were that GRIP was significantly higher in older physicians, in male physicians, among those who less involved their patients in decisions, and those who were not training supervisors. For GRID, results were quite similar to those of GRIP. GS was significantly higher for physicians working in health centres or medical homes and for those with gynecological practices but lower when they less involved patients in medical decisions. This study suggests that it is necessary to teach gender issues not only in medical schools but also as part of continuing medical education.


Assuntos
Medicina Geral , Clínicos Gerais , Glutamina/análogos & derivados , Humanos , Masculino , Feminino , Idoso , Estudos Transversais , Inquéritos e Questionários , Sexismo , França
11.
J Food Sci ; 89(3): 1305-1306, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38462990

Assuntos
Sexismo
12.
Can Med Educ J ; 15(1): 48-55, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-38528899

RESUMO

Background: Female physicians and patients experience gender bias in healthcare. The purpose of this research is to explore medical students' gender bias toward physicians and patients and whether their bias varies by gender. Methods: We surveyed medical students at Memorial University between November 2020 and April 2021. We recruited participants through Facebook, email, and e-posters. We collected demographic information, including gender and class year. We used the Nijmegen Gender Awareness in Medicine Scale to measure gender sensitivity, gender role ideology toward patients, and gender role ideology toward doctors. We analyzed the data using averages and t-tests. Results: Mean gender sensitivity scores were 4/5 indicating high gender sensitivity. Gender role ideology toward doctors mean scores were 2/5 indicating that students did not hold strong stereotypical views toward doctors. Although male students scored higher than female students (p<.05), mean scores for gender role ideology toward patients were low for both male and female students (x¯ <2), indicating low stereotyping toward patients. Conclusions: We found that students held largely non-biased ideologies surrounding gender in medicine and that female students were even less biased than male students for gender role ideology toward patients.


Contexte: Les femmes médecins ou patientes sont victimes de préjugés sexistes dans les soins de santé. L'objectif de cette recherche est d'explorer les préjugés sexistes des étudiants en médecine à l'égard des médecins et des patients et de déterminer si ces préjugés varient en fonction du sexe. Méthodes: Nous avons procédé à une enquête auprès des étudiants en médecine de l'Université Memorial entre novembre 2020 et avril 2021. Nous avons recruté des participants au moyen de Facebook, du courrier électronique et d'affiches électroniques. Nous avons recueilli des données démographiques, y compris le sexe et l'année dans le programme. Nous avons utilisé l'échelle de sensibilisation au genre en médecine de Nijmegen pour mesurer la sensibilité au genre, l'idéologie du rôle du genre envers les patients et l'idéologie du rôle du genre envers les médecins. Nous avons analysé les données à l'aide de moyennes et de tests t. Résultats: Les scores moyens de sensibilité au genre étaient de 4/5, ce qui indique une grande sensibilité au genre. Les scores moyens de l'idéologie du rôle du genre à l'égard des médecins étaient de 2/5, ce qui indique que les étudiants n'avaient pas d'opinion stéréotypée à l'égard des médecins. Bien que les étudiants aient obtenu des scores plus élevés que les étudiantes (p<0,05), les scores moyens pour l'idéologie du rôle du genre à l'égard des patients étaient faibles tant pour les étudiants que pour les étudiantes (x¯<2), ce qui indique un faible niveau d'opinions stéréotypées à l'égard des patients. Conclusions: Nous avons constaté que les étudiants avaient des idéologies largement non biaisées concernant le genre en médecine et que les étudiantes étaient encore moins biaisées que les étudiants en ce qui concerne l'idéologie du rôle du genre envers les patients.


Assuntos
Médicos , Estudantes de Medicina , Humanos , Masculino , Feminino , Terra Nova e Labrador/epidemiologia , Sexismo , Estereotipagem
13.
Rev. esp. geriatr. gerontol. (Ed. impr.) ; 59(1): [101432], ene.-feb. 2024. ilus, graf
Artigo em Espanhol | IBECS | ID: ibc-EMG-478

RESUMO

Antecedentes y objetivos El edadismo es la percepción negativa de las personas por su edad. El objetivo de esta investigación fue analizar los niveles de edadismo y su asociación con el sexismo y otros factores en universitarios. Materiales y métodos Se llevó a cabo un estudio transversal a través de una encuesta online entre los estudiantes de la Universidad de Granada (España). Se recogió información sobre variables sociodemográficas y académicas y se administró el Cuestionario de estereotipos negativos hacia la vejez (CENVE), la Escala de sexismo ambivalente (ASI), el Cuestionario breve de los cinco grandes rasgos de personalidad (BFPTSQ), la Escala sobre la ansiedad por el envejecimiento (AE) y la Escala sobre el contacto con personas mayores (CPM). Se determinaron los niveles de edadismo y se exploraron asociaciones con otras variables. A continuación, se realizó un modelo de regresión logística binaria para conocer los factores asociados a su presencia. Resultados Participaron doscientos sesenta y tres (263) estudiantes. La mayoría presentaban niveles de edadismo bajos o muy bajos (83,3%). Los estudiantes más edadistas presentaban mayores niveles de sexismo hostil (OR=1,07; p<0,01) y más ansiedad por el envejecimiento (OR=1,10; p<0,05) que los estudiantes que puntuaron bajo en edadismo. Por otra parte, ser alumno de grado fue un factor protector frente a este tipo de sesgo comparado con la realización de estudios de posgrado (OR=0,31; p<0,05). Conclusión Un mayor sexismo hostil y una mayor ansiedad por el envejecimiento se relacionan con un mayor edadismo en los estudiantes de la Universidad de Granada (España). Las universidades deben brindar conocimiento a sus alumnos sobre este problema y desarrollar programas dirigidos a evitar la discriminación de las personas mayores. (AU)


Background and aims Ageism is the negative perception towards others based on age. The aim of this research was to analyze the levels of ageism and its association with sexism and other factors in university students. Materials and methods Cross-sectional study among the students of the University of Granada. The data was collected through an online survey. Information on sociodemographic and academic variables was collected together with the Negative Stereotypes Questionnaire towards Old Age (CENVE), the Ambivalent Sexism Scale (ASI), the Brief Version of the Big Five Personality Inventory (BFPTSQ), the Anxiety Scale for Aging (AE) and the Contact with the Elderly Scale (CPM). Ageism levels were determined and associations with other variables were analyzed. A logistic regression model explored ageism’ associated factors. Results Two hundred and sixty-three students participated. Most had low or very low levels of ageism (83.3%). The most ageist students showed higher hostile sexism (OR=1.07; p<.01) and higher aging anxiety (OR=1.10; p<.05) than students with high scores in ageism. Graduate students showed protector OR for ageism when compared to postgraduate students (OR=.31; p<.05). Conclusions Higher hostile sexism and aging anxiety are associated with higher ageism in students from the University of Granada. Universities must include in their study plans knowledge about this problem and develop programs aimed at avoiding discrimination in the elderly. (AU)


Assuntos
Humanos , Etarismo , Sexismo , Estudantes , Estudos Transversais , Espanha
14.
Matern Child Health J ; 28(3): 431-437, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38379060

RESUMO

INTRODUCTION: Recent studies demonstrate that structural sexism erodes women's health and impedes access to healthcare. This study extends this research to examine the relationship between structural sexism and breastfeeding initiation and duration in the United States. METHOD: A multifaceted state-level structural sexism index was constructed and merged with responses from the 2016-2021 National Survey of Children's Health by state and child's birth year. For children ages six months to 5 years, the prevalence of being ever breastfed and breastfed for at least six months was measured across levels of structural sexism. Multivariable logistic regression analyzed the association of structural sexism with breastfeeding outcomes, net of individual and family characteristics. RESULTS: Higher levels of structural sexism were associated with lower odds of breastfeeding initiation and lower odds of breastfeeding for at least six months net of family and child characteristics. In addition, sensitivity analyses show that variations in state breastfeeding laws did not explain these differences. DISCUSSION: This study highlights structural sexism's role in limiting breastfeeding initiation and duration. Breastfeeding promotions and guidelines should consider the broader context of structural sexism.


Assuntos
Aleitamento Materno , Sexismo , Criança , Humanos , Feminino , Estados Unidos , Cognição , Características da Família , Instalações de Saúde
15.
Nature ; 626(8001): 1049-1055, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-38355800

RESUMO

Each year, people spend less time reading and more time viewing images1, which are proliferating online2-4. Images from platforms such as Google and Wikipedia are downloaded by millions every day2,5,6, and millions more are interacting through social media, such as Instagram and TikTok, that primarily consist of exchanging visual content. In parallel, news agencies and digital advertisers are increasingly capturing attention online through the use of images7,8, which people process more quickly, implicitly and memorably than text9-12. Here we show that the rise of images online significantly exacerbates gender bias, both in its statistical prevalence and its psychological impact. We examine the gender associations of 3,495 social categories (such as 'nurse' or 'banker') in more than one million images from Google, Wikipedia and Internet Movie Database (IMDb), and in billions of words from these platforms. We find that gender bias is consistently more prevalent in images than text for both female- and male-typed categories. We also show that the documented underrepresentation of women online13-18 is substantially worse in images than in text, public opinion and US census data. Finally, we conducted a nationally representative, preregistered experiment that shows that googling for images rather than textual descriptions of occupations amplifies gender bias in participants' beliefs. Addressing the societal effect of this large-scale shift towards visual communication will be essential for developing a fair and inclusive future for the internet.


Assuntos
Ocupações , Fotografação , Sexismo , Mídias Sociais , Feminino , Humanos , Masculino , Ocupações/estatística & dados numéricos , Fotografação/estatística & dados numéricos , Fotografação/tendências , Opinião Pública , Sexismo/prevenção & controle , Sexismo/psicologia , Sexismo/estatística & dados numéricos , Sexismo/tendências , Mídias Sociais/estatística & dados numéricos , Mudança Social
16.
BMC Public Health ; 24(1): 374, 2024 02 05.
Artigo em Inglês | MEDLINE | ID: mdl-38317123

RESUMO

BACKGROUND: On line platforms offer access to an almost unlimited variety of pornographic material that shows high levels of sexism. Despite this fact, there are still few studies that assess the effect of pornography on sexism in young adults The aim of this study is to analyze the association of pornography consumption and sexual orientation with benevolent sexism (BS) and hostile sexism (HS) in young men and women. METHODS: We surveyed 2,346 people aged 18-35 years old. Multiple regression models were carried out for BS and HS. The independent variables: current pornography consumption and sexual orientation. Covariates: socio-demographic variables -age, sex, level of education and place of birth-. RESULTS: A) HS: Men who consumed pornography had higher median values of HS than those who did not [ß(95%CI):2.39(0.67;4.10)]. Homosexual/ bisexual men displayed lower values of HS than heterosexual men [ß(95%CI):-2.98(-4.52;-1.45)]. The increase in HS levels associated with pornography consumption was notably greater in homosexual and bisexual women relative to heterosexual women, where that pattern was not observed [ß(95%CI for interaction): 2.27(0.11; 4.43)]. B) BS: Mean values of BS were observed to be lower for both women [ß(95%CI):-2.16(-2.99;-1.32)] and men [ß(95%CI):-4.30(-5.75;-2.86)] who consumed pornography compared to those who did not. Homosexual/bisexual men recorded mean values of BS lower than heterosexual men [ß(95%CI):-3.10(-4.21;-1.99)]. CONCLUSIONS: Pornography consumption is related to sexism and differs according to sex and sexual orientation. As sexism is the substratum of inequality between men and women, it is urgent to launch affective-sexual education programs for young people that take into account the determinants of sexism.


Assuntos
Literatura Erótica , Sexismo , Humanos , Feminino , Masculino , Adulto Jovem , Adolescente , Adulto , Espanha , Comportamento Sexual , Heterossexualidade
18.
J Ethnobiol Ethnomed ; 20(1): 20, 2024 Feb 19.
Artigo em Inglês | MEDLINE | ID: mdl-38373968

RESUMO

BACKGROUND: The use of medicinal plants is integral to global healthcare systems, with Sub-Saharan Africa maintaining a robust tradition of herbal medicine alongside Western-oriented healthcare. As migrant communities tend to continue traditional herbal practices after migration, documenting this use is vital to develop culturally sensitive healthcare. This study investigates plant usage and perspectives in the context of sexual and reproductive health among the Congolese community in Belgium, particularly in the Matongé quarter of Brussels. Our research questions were: (1) What is the current knowledge of medicinal plants among the Congolese community in Belgium in the context of sexual health, and what are the applications and commonly employed administration methods of these plants? (2) What role does herbal medicine play in the context of sexual health for people of Congolese descent in Belgium and how this is influenced by perceptions of sexuality? and (3) Is there a gender bias in the use of medicinal plants, and if so, can this be related to perceived gender norms? METHODS: We conducted 22 semi-structured interviews with people of Congolese descent currently living in Belgium. Participants were selected using both snowball sampling and purposive sampling. Plant use in the context of sexual health was recorded through freelisting. Data on narratives, ideas, and perceptions of this plant use in the context of sexual health were collected. Interview transcripts were analyzed using thematic analysis. RESULTS: We identified 17 plant species used for sexual health. Three overarching themes emerged from our data. Plants were used with a notable gender bias favoring male sexual potency enhancement. Men used these plants for both remedying potency issues and enhancing sexual prowess. In contrast, knowledge about plants for female sexual health was limited. Gender norms reinforced the importance of male sexual potency, while stigmatizing open discussions of female sexuality. CONCLUSIONS: The use of medicinal plants for sexual health raises health, social, and conservation concerns, underscoring the need for further research in this area. This study contributes to understanding medicinal plant use within the Congolese community in Belgium and highlights the necessity for future research on herbal practices for female sexual health in this context.


Assuntos
Plantas Medicinais , Saúde Sexual , Humanos , Masculino , Feminino , Etnobotânica , Bélgica , Sexismo , Extratos Vegetais , Fitoterapia
19.
Science ; 383(6685): 822-825, 2024 Feb 23.
Artigo em Inglês | MEDLINE | ID: mdl-38386730

RESUMO

Several widely used high school biology texts depart from established science.


Assuntos
Biologia , Sexo , Estereotipagem , Humanos , Biologia/educação , Estados Unidos , Sexismo
20.
Mol Autism ; 15(1): 10, 2024 Feb 21.
Artigo em Inglês | MEDLINE | ID: mdl-38383466

RESUMO

BACKGROUND: A growing body of evidence suggests that immune dysfunction and inflammation in the peripheral tissues as well as the central nervous system are associated with the neurodevelopmental deficits observed in autism spectrum disorder (ASD). Elevated expression of pro-inflammatory cytokines in the plasma, serum, and peripheral blood mononuclear cells of ASD has been reported. These cytokine expression levels are associated with the severity of behavioral impairments and symptoms in ASD. In a prior study, our group reported that tumor necrosis factor-α (TNF-α) expression in granulocyte-macrophage colony-stimulating factor-induced macrophages (GM-CSF MΦ) and the TNF-α expression ratio in GM-CSF MΦ/M-CSF MΦ (macrophage colony-stimulating factor-induced macrophages) was markedly higher in individuals with ASD than in typically developed (TD) individuals. However, the mechanisms of how the macrophages and the highly expressed cytokines affect neurons remain to be addressed. METHODS: To elucidate the effect of macrophages on human neurons, we used a co-culture system of control human-induced pluripotent stem cell-derived neurons and differentiated macrophages obtained from the peripheral blood mononuclear cells of five TD individuals and five individuals with ASD. All participants were male and ethnically Japanese. RESULTS: Our results of co-culture experiments showed that GM-CSF MΦ affect the dendritic outgrowth of neurons through the secretion of pro-inflammatory cytokines, interleukin-1α and TNF-α. Macrophages derived from individuals with ASD exerted more severe effects than those derived from TD individuals. LIMITATIONS: The main limitations of our study were the small sample size with a gender bias toward males, the use of artificially polarized macrophages, and the inability to directly observe the interaction between neurons and macrophages from the same individuals. CONCLUSIONS: Our co-culture system revealed the non-cell autonomous adverse effects of GM-CSF MΦ in individuals with ASD on neurons, mediated by interleukin-1α and TNF-α. These results may support the immune dysfunction hypothesis of ASD, providing new insights into its pathology.


Assuntos
Transtorno do Espectro Autista , Citocinas , Feminino , Masculino , Humanos , Fator Estimulador de Colônias de Granulócitos e Macrófagos/metabolismo , Fator Estimulador de Colônias de Granulócitos e Macrófagos/farmacologia , Fator Estimulador de Colônias de Macrófagos/metabolismo , Fator Estimulador de Colônias de Macrófagos/farmacologia , Fator de Necrose Tumoral alfa/metabolismo , Fator de Necrose Tumoral alfa/farmacologia , Leucócitos Mononucleares/metabolismo , Interleucina-1alfa/metabolismo , Interleucina-1alfa/farmacologia , Transtorno do Espectro Autista/metabolismo , Células Cultivadas , Sexismo , Macrófagos/metabolismo , Granulócitos/metabolismo , Dendritos/metabolismo
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