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1.
Zootaxa ; 5419(1): 145-150, 2024 Mar 05.
Artigo em Inglês | MEDLINE | ID: mdl-38480331

RESUMO

We found Albiphasma heringi (Mell, 1922) and A. pieridoides (Liu & Gu, 1994) to be conspecific by the 658 bp COI gene sequences and male genitalia characters. Considering the distinguishable wing patterns and allopatric distribution of the two taxa, we treat pieridoides as a subspecies of heringi. Therefore, the genus Albiphasma Huang, Chiba, Wang and Fan, 2016, which was established for heringi and pieridoides, becomes monotypic, and in light of morphological similarities and close genetic distance between heringi and Pintara bowringi (Joicey & Talbot, 1921), we propose its synonymy with Pintara Evans, 1932. The adults and male genitalia of both P. heringi heringi (Mell, 1922) and P. heringi pieridoides (Liu & Gu, 1994) are illustrated.


Assuntos
Borboletas , Masculino , Animais , Genitália Masculina
2.
Zootaxa ; 5418(3): 240-254, 2024 Feb 29.
Artigo em Inglês | MEDLINE | ID: mdl-38480359

RESUMO

A new record of the rare species Mirocastnia pyrrhopygoides (Houlbert) from Ecuador is reported, along with range extensions for M. smalli (J. Y. Miller) and M. canis (Lathy). In addition, the genus Mirocastnia J. Y. Miller is revised and the diagnostic phenotypic characteristics of males and females, as well as male genitalia, are illustrated. Details on its natural history, biogeography, and biology are included with the purpose of solving the confusion in the taxonomy of the genus. All taxa previously considered to be species are herein relegated to subspecific status, i.e. M. pyrrhopygoides canis stat. nov. and M. p. smalli stat. nov.


Assuntos
Lepidópteros , Mariposas , Feminino , Masculino , Animais , Genitália Masculina , Manejo de Espécimes , Genitália , Distribuição Animal
3.
Zootaxa ; 5403(3): 377-384, 2024 Jan 22.
Artigo em Inglês | MEDLINE | ID: mdl-38480431

RESUMO

The Taiwanese species of Microleon are reviewed with morphological and DNA data. Our review recognized two congeners, including a new species, M. taiwanensis n. sp. and one known species, M. longipalpis Butler, 1885. The findings from this study request a reconsideration of the previous records of Microleon from Taiwan. The minor differences in external appearance among the species of Microleon pose a challenge for reliable identification. Our study shows that examination of the male genitalia and COI barcoding helps distinguish the species. A checklist of the world species of Microleon with their distributional range is provided.


Assuntos
Lepidópteros , Masculino , Animais , Lepidópteros/genética , Taiwan , Código de Barras de DNA Taxonômico , Genitália Masculina , DNA
4.
Curr Biol ; 34(5): 1114-1121.e7, 2024 Mar 11.
Artigo em Inglês | MEDLINE | ID: mdl-38309269

RESUMO

The emergence and diversification of morphological novelties is a major feature of animal evolution.1,2,3,4,5,6,7,8,9 However, relatively little is known about the genetic basis of the evolution of novel structures and the mechanisms underlying their diversification. The epandrial posterior lobes of male genitalia are a novelty of particular Drosophila species.10,11,12,13 The lobes grasp the female ovipositor and insert between her abdominal tergites and, therefore, are important for copulation and species recognition.10,11,12,14,15,16,17 The posterior lobes likely evolved from co-option of a Hox-regulated gene network from the posterior spiracles10 and have since diversified in morphology in the D. simulans clade, in particular, over the last 240,000 years, driven by sexual selection.18,19,20,21 The genetic basis of this diversification is polygenic but, to the best of our knowledge, none of the causative genes have been identified.22,23,24,25,26,27,28,29,30 Identifying the genes underlying the diversification of these secondary sexual structures is essential to understanding the evolutionary impact on copulation and species recognition. Here, we show that Sox21b negatively regulates posterior lobe size. This is consistent with expanded Sox21b expression in D. mauritiana, which develops smaller posterior lobes than D. simulans. We tested this by generating reciprocal hemizygotes and confirmed that changes in Sox21b underlie posterior lobe evolution between these species. Furthermore, we found that posterior lobe size differences caused by the species-specific allele of Sox21b significantly affect copulation duration. Taken together, our study reveals the genetic basis for the sexual-selection-driven diversification of a novel morphological structure and its functional impact on copulatory behavior.


Assuntos
Evolução Biológica , Drosophila , Animais , Feminino , Masculino , Copulação/fisiologia , Drosophila/fisiologia , Genitália Masculina/anatomia & histologia
5.
J Trace Elem Med Biol ; 83: 127403, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38340548

RESUMO

Successful male fertilization requires the main processes such as normal spermatogenesis, sperm capacitation, hyperactivation, and acrosome reaction. The progress of these processes depends on some endogenous and exogenous factors. So, the optimal level of ions and essential and rare elements such as selenium, zinc, copper, iron, manganese, calcium, and so on in various types of cells of the reproductive system could affect conception and male fertility rates. The function of trace elements in the male reproductive system could be exerted through some cellular and molecular processes, such as the management of active oxygen species, involvement in the action of membrane channels, regulation of enzyme activity, regulation of gene expression and hormone levels, and modulation of signaling cascades. In this review, we aim to summarize the available evidence on the role of trace elements in improving male reproductive performance. Also, special attention is paid to the cellular aspects and the involved molecular signaling cascades.


Assuntos
Oligoelementos , Masculino , Humanos , Oligoelementos/metabolismo , Espermatozoides/metabolismo , Sêmen , Transdução de Sinais , Genitália Masculina
6.
MMW Fortschr Med ; 166(3): 29, 2024 02.
Artigo em Alemão | MEDLINE | ID: mdl-38389004
7.
Int J Mol Sci ; 25(4)2024 Feb 06.
Artigo em Inglês | MEDLINE | ID: mdl-38396655

RESUMO

The immunological aspects of male infertility have gradually become the focus of both basic and clinical research [...].


Assuntos
Genitália Masculina , Masculino , Humanos
8.
Wound Repair Regen ; 32(2): 171-181, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38351501

RESUMO

Keloid is the maximum expression of pathological fibroproliferative skin wound healing, whose pathophysiology is not yet fully understood. Its occurrence in the perineum and genitalia is uncommon. A systematic review was carried out regarding the occurrence and treatment of keloids on the penis. An illustrative case was also reported. The review used the PRISMA checklist and was registered in PROSPERO. The entire literature period up to April 2023 was searched in the EMBASE/Elsevier, Cochrane, Scopus, Medline, BVS, SciELO, and Lilacs databases. The inclusion criteria embraced primary studies, clinical trials, prospective or retrospective cohorts, case series, case-control studies and case reports. Three hundred and sixty-one studies were found and 12 of them were included, consisting of 9 case reports and 3 case series. The most common triggering factor for keloid formation was circumcision, in 11 of the cases, of which more than half occurred in prepubescent children. Several therapies, associated or isolated, were used to treat the cases. Only one of the reported patients had scar recurrence after surgical treatment. Studies with better scientific evidence are needed to understand the involvement of keloids in male genitalia. However, keloid formation in this topography is rare, making it difficult to carry out more elaborate studies.


Assuntos
Queloide , Criança , Humanos , Masculino , Queloide/patologia , Estudos Retrospectivos , Estudos Prospectivos , Cicatrização , Genitália Masculina/cirurgia , Genitália Masculina/patologia
9.
Sci Total Environ ; 922: 171299, 2024 Apr 20.
Artigo em Inglês | MEDLINE | ID: mdl-38423318

RESUMO

After aging in the environment, some nanoplastics will carry different charges and functional groups, thereby altering their toxicological effects. To evaluate the potential impact of aging of nanoplastics on the mammalian reproductive system, we exposed C57BL/6 male mice to a dose of 5 mg/kg/d polystyrene nanoparticles (PS-NPs) with different functional groups (unmodified, carboxyl functionalized and amino functionalized) for 45 days for this study. The results suggest that PS-NPs with different functional groups triggered oxidative stress, a decreased in the testis index, disruption of the outer wall of the seminiferous tubules, reduction in the number of spermatogonia cells and sperm counts, and an increased in sperm malformations. We performed GO and KEGG enrichment analysis on the differentially expressed proteins, and found they were mainly enriched in protein transport, RNA splicing and mTOR signaling. We confirmed that the PI3K-AKT-mTOR pathway is over activated, which may lead to reduction of spermatogonia stem cells by over differentiation. Strikingly, PS-NPs with functional group modifications are more toxic than those of unmodified polystyrene, and that PS-NPs with positively charged amino modifications are the most toxic. This study provides a new understanding for correctly evaluating the toxicological effects of plastic aging, and of the mechanism responsible for the reproductive toxicity caused by nanoplastics.


Assuntos
Nanopartículas , Poluentes Químicos da Água , Animais , Camundongos , Masculino , Poliestirenos/toxicidade , Poliestirenos/metabolismo , Microplásticos , Camundongos Endogâmicos C57BL , Fosfatidilinositol 3-Quinases , Poluentes Químicos da Água/toxicidade , Sêmen , Nanopartículas/toxicidade , Nanopartículas/metabolismo , Genitália Masculina/metabolismo , Serina-Treonina Quinases TOR , Mamíferos/metabolismo
10.
Proc Biol Sci ; 291(2015): 20232883, 2024 Jan 31.
Artigo em Inglês | MEDLINE | ID: mdl-38290544

RESUMO

Animal genitalia are thought to evolve rapidly and divergently in response to sexual selection. Studies of genital evolution have focused largely on male genitalia. The paucity of work on female genital morphology is probably due to problems faced in quantifying shape variation, due to their composition and accessibility. Here we use a combination of micro-computed tomography, landmark free shape quantification and phylogenetic analysis to quantify the rate of female genital shape evolution among 29 species of Antichiropus millipedes, and their coevolution with male genitalia. We found significant variation in female and male genital shape among species. Male genital shape showed a stronger phylogenetic signal than female genital shape, although the phylogenetic signal effect sizes did not differ significantly. Male genital shape was found to be evolving 1.2 times faster than female genital shape. Female and male genital shape exhibited strong correlated evolution, indicating that genital shape changes in one sex are associated with corresponding changes in the genital shape of the other sex. This study adds novel insight into our growing understanding of how female genitalia can evolve rapidly and divergently, and highlights the advantages of three-dimensional techniques and multivariate analyses in studies of female genital evolution.


Assuntos
Artrópodes , Evolução Biológica , Animais , Masculino , Feminino , Filogenia , Microtomografia por Raio-X , Genitália Masculina/anatomia & histologia , Genitália Feminina/anatomia & histologia , Artrópodes/anatomia & histologia
11.
Micron ; 178: 103591, 2024 03.
Artigo em Inglês | MEDLINE | ID: mdl-38241905

RESUMO

Changes in harvesting methods in the early 1990s led to Mahanarva fimbriolata becoming the most prevalent pest in sugarcane plantations. Encouraged by the scarcity of research on the reproductive system and spermatology of Auchenorrhyncha, we provide a detailed description of the male reproductive system and spermatozoa of this cercopid. This will not only aid in taxonomic purposes but also help in understanding the reproductive biology of the species. The male reproductive system, spermatozoa, and sperm bundles of M. fimbriolata were investigated using light microscopy. Our results reveal a reproductive system consisting of a pair of testes, each with 36 follicles, two vasa deferentia, two well-developed seminal vesicles, a single pair of accessory glands, and an ejaculatory duct. Here, we also describe and explore the particularities of the formation of secondary sperm bundles, where cells interestingly bind only to the apical region of the spermatostyle. We also propose some possible benefits of this unusual organization for the reproductive success of the species.


Assuntos
Hemípteros , Masculino , Animais , Sementes , Espermatozoides , Genitália Masculina/anatomia & histologia , Testículo
12.
J Toxicol Environ Health A ; 87(6): 266-273, 2024 Mar 18.
Artigo em Inglês | MEDLINE | ID: mdl-38166509

RESUMO

Benzophenone-3 (BP-3, 2-hydroxy-4-methoxybenzophenone, oxybenzone) is one of the most widely used types of benzophenone organic sunscreen. However, this compound is a potentially harmful toxicant. The aim of this study was 2-fold to: (1) utilize a Hershberger bioassay in vivo in castrated male Sprague-Dawley rats to investigate the anti-androgenic activities of BP-3, and (2) use in vitro a methyl tetrazolium assay to compare the toxicity between Leydig cells (TM3 cells) and mouse fibroblast (NIH-3T3) cell lines. In the Hershberger assay, rats were divided into 6 groups (each of n = 7): a vehicle control, negative control, positive control, PB-3 low (40 mg/kg), BP-3 intermediate (200 mg/kg), and BP-3 high (1000 mg/kg)-dose. The weight of the ventral prostate was significantly decreased at BP-3 doses of 200 or 1,000 mg/kg/day. In addition, the levator anibulbocavernosus muscle weights were also significantly reduced at BP-3 doses of 40, 200, or 1,000 mg/kg/day. In the MTT assay, the viability of NIH-3T3 mouse fibroblast cells was within the normal range. However, the TM3 mouse testis Leydig cell viability was significantly lowered in a concentration-dependent manner. Therefore, data indicate that BP-3 might exert in vivo anti-androgenic and in vitro cytotoxic effects in cells associated with the male reproductive system compared to normal non-reproductive cells.Abbreviation: BP-3: benzophenone-3; CG: Cowper's gland; DMEM: Dulbecco's modified Eagle's medium; DMSO: dimethyl sulfoxide; GP: glans penis; LABC: levator anibulbocavernosus muscle; MTT: methyl tetrazolium; NC: negative control; PC: positive control; SV: seminal vesicle; TP: testosterone propionate; VC: vehicle control; VP: ventral prostate.


Assuntos
Antineoplásicos , Orquiectomia , Camundongos , Ratos , Masculino , Animais , Ratos Sprague-Dawley , Antagonistas de Androgênios/farmacologia , Benzofenonas/toxicidade , Antineoplásicos/farmacologia , Tamanho do Órgão , Genitália Masculina
13.
Zootaxa ; 5399(3): 287-295, 2024 Jan 12.
Artigo em Inglês | MEDLINE | ID: mdl-38221154

RESUMO

A series of specimens with some differences in wing patterns and male genitalia from different localities is recognized as Halpe paupera Devyatkin, 2002 by comparing the COI gene sequences. The morphological variability in male is discussed and illustrated. The intraspecific variation of the female of H. paupera walthewi Devyatkin, 2002 from the type locality is elucidated, and hence this subspecies is considered a synonym of H. paupera paupera. A distribution map and some bionomic information of the species are provided.


Assuntos
Lepidópteros , Feminino , Masculino , Animais , Lepidópteros/genética , Genitália Masculina
14.
Vet Med Sci ; 10(1): e31351, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-38227711

RESUMO

BACKGROUND: Various infectious agents can infect the male reproductive system. OBJECTIVES: The aims of this study were to provide current data on fungal and yeast flora of the external organs of reproductive system of male short hair cats including penis and prepuce. METHODS: In total 28 samples were taken from external genital system of male stray cats using sterilised cotton swabs. Samples were taken based on the absence of any reproductive complications using physical examinations. The samples were transferred to sterilised Stuart transport media and were then incubated in the Sabouraud dextrose agar with chloramphenicol at 32°C for 48 h. The identification of fungi and yeasts was confirmed by germ tube formation test, CHROM agar, urease testing and Corn meal agar medium with Tween 80. RESULTS: Fungal agents were isolated from 7 (25%) out of 28 male stray cats. Fungal isolates were obtained from the penis and prepuce of 4 (36%) and 7 (100%) male cats, respectively. The most commonly recovered species samples were Candida krusei (3.75%) and Penicillum spp. (6.86%) from the penis and prepuce of the cats, respectively. The external organs of male reproduction of cats were infected with 2-4 different fungal agents. Only 5 (45%) cats were infected with one fungus; however, in 6 (55%) cats, mixed fungal infections were isolated. Cats 3-4 years old had the highest fungal contamination in the prepuce region (4/7), while the penis at this age had the least contamination (1/4). CONCLUSIONS: It is concluded that the external reproduction organs of male cats could be infected by different fungal agents.


Assuntos
Doenças do Gato , Micoses , Gatos , Masculino , Animais , Feminino , Ágar , Micoses/veterinária , Genitália Masculina , Meios de Cultura , Saccharomyces cerevisiae , Reprodução
15.
Am J Mens Health ; 18(1): 15579883241228243, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38279822

RESUMO

This study compares the rate of selected types of mental illnesses (stress, anxiety, depression) and sleep disorders (insomnia, sleep apnea) according to the status of eight male genital problems. Analyses utilize medical claims data for male employees aged 18 to 64 years of a large corporation, 2017 to 2021. Approximately 1,076 (7.3%) men per year have one or more genital problems. The most common being benign prostatic hyperplasia (BPH; 3.8%) and then erectile dysfunction (ED; 1.7%). For BPH patients, the rate experiencing stress, anxiety, depression, or a combination of these is 0.96%, 6.2%, 5.3%, and 5.1%, respectively. Corresponding rates for ED are 1.5%, 7.2%, 5.9%, and 7.5%. For BPH patients, the rate experiencing insomnia, sleep apnea, or both is 3.1%, 22.7%, and 2.0%, respectively. Corresponding rates for ED are 1.2%, 20.6%, and 2.2%. Male genital problems positively associate with having one or more mental illnesses (stress, anxiety, depression), except for hydrocele, with ED and penis disorder having the strongest associations. Male genital problems also positively associate with having insomnia and/or sleep apnea, except for infertility and orchitis, with BPH and ED having the strongest associations. The positive associations involving BPH and ED with mental illnesses are each more pronounced in the younger age group (18-49 vs. 50-64). Similar results are seen in the models involving sleep disorders. Thus, comorbid male genital problems, mental illnesses, and sleep disorders exist, with the strength of associations unique to the male genital problem and sometimes modified by age.


Assuntos
Disfunção Erétil , Hiperplasia Prostática , Síndromes da Apneia do Sono , Distúrbios do Início e da Manutenção do Sono , Transtornos do Sono-Vigília , Humanos , Masculino , Feminino , Distúrbios do Início e da Manutenção do Sono/epidemiologia , Hiperplasia Prostática/complicações , Disfunção Erétil/epidemiologia , Síndromes da Apneia do Sono/complicações , Transtornos do Sono-Vigília/epidemiologia , Transtornos do Sono-Vigília/complicações , Genitália Masculina
16.
Anat Histol Embryol ; 53(1): e12997, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-37971195

RESUMO

There are few scientific reports on the histology of the phallus of ratite birds. The aim of this study was to conduct a histochemical analysis to determine the distribution of smooth muscle cells and the volumetric density (Vv) of the fibres of the elastic system in the ostrich phallus. Adult ostriches, 14 months old, were used. The phalluses were fixed in Bouin's solution and then transferred to a buffered formalin solution. They were then processed using standard histological stains for paraffin and slices were obtained. The following techniques were performed: HE, Picrosirius red, Alcian Blue at pH 1.0 and 2.5. The Periodic acid-Schiff reagent and Weigert's Resorcin-Fuchsin with previous oxidation were performed. The M42 test system was used to quantify the elastic system fibres. For immunohistochemical analysis, an anti alpha smooth muscle actin monoclonal antibody was used. The surface of the phallus is covered by a non-keratinized stratified squamous epithelium, which becomes stratified cylindrical in the region of the spermatic sulcus. No glands associated with the connective tissue were observed. The Vv of the elastic system fibres was 4.75%. Smooth muscle cells were visualized only in the walls of blood vessels through immunostaining, with an absence in the lymphatic sinuses. Despite similarities with other birds, such as the presence of a fibrous external axis, a lymphatic core, and a spermatic groove, the ostrich phallus shows marked differences, including the absence of an elastic core, a non-keratinized lining epithelium, and the absence of glands throughout its extension.


Assuntos
Struthioniformes , Masculino , Animais , Tecido Elástico , Tecido Conjuntivo , Genitália Masculina , Músculo Liso
17.
Evolution ; 78(2): 329-341, 2024 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-38006287

RESUMO

Rapid genitalia evolution is believed to be mainly driven by sexual selection. Recently, noncopulatory genital functions have been suggested to exert stronger selection pressure on female genitalia than copulatory functions. In bedbugs (Cimicidae), the impact of the copulatory function can be isolated from the noncopulatory impact. Unlike in other taxa, female copulatory organs have no function in egg-laying or waste-product expulsion. Males perform traumatic mating by piercing the female integument, thereby imposing antagonistic selection on females and suspending selection to morphologically match female genitalia. We found the location of the copulatory organ evolved rapidly, changing twice between dorsal and ventral sides, and several times along the anteroposterior and the left-right axes. Male genital length and shape varied much less, did not appear to follow the positional changes seen in females, and showed no evidence for coevolution. Female genitalia position evolved 1.5 times faster than male genital length and shape and showed little neutral or geographic signals. Instead, we propose that nonmorphological male traits, such as mating behavior, may drive female genitalia morphology in this taxon. Models of genitalia evolution may benefit from considering morphological genital responses to nonmorphological stimuli, such as male mating behavior or copulatory position.


Assuntos
Percevejos-de-Cama , Comportamento Sexual Animal , Animais , Feminino , Masculino , Comportamento Sexual Animal/fisiologia , Evolução Biológica , Genitália Feminina/anatomia & histologia , Genitália/anatomia & histologia , Genitália Masculina/anatomia & histologia
18.
Neotrop Entomol ; 53(1): 56-62, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-38017312

RESUMO

Phoebella Lane, 1966 is a Neotropical genus of flat-faced longhorned beetles (Cerambycidae, Lamiinae, Hemilophini) with three species. Here, a new species, Phoebella queirozae sp. nov., is described from the state of Ceará (Brazil). The male terminalia of Phoebella phoebe (Lepeletier and Audinet-Serville, 1825) is described for the first time. The external morphology and male terminalia of the new species and P. phoebe are compared, and the value of male terminalia characters in the taxonomy of longhorned beetles is briefly discussed.


Assuntos
Besouros , Masculino , Animais , Brasil , Genitália Masculina
19.
Prostate ; 84(1): 8-24, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-37888416

RESUMO

BACKGROUND: Over the last 20 years, fructose has gradually emerged as a potential metabolic substrate capable of promoting the growth and progression of various cancers, including prostate cancer (PCa). The biological and molecular mechanisms that underlie the effects of fructose on cancer are beginning to be elucidated. METHODS: This review summarizes the biological function of fructose as a potential carbon source for PCa cells and its role in the functionality of the male reproductive tract under normal conditions. RESULTS: The most recent biological advances related to fructose transport and metabolism as well as their implications in PCa growth and progression suggest that fructose represent a potential carbon source for PCa cells. Consequently, fructose derivatives may represent efficient radiotracers for obtaining PCa images via positron emission tomography and fructose transporters/fructose-metabolizing enzymes could be utilized as potential diagnostic and/or predictive biomarkers for PCa. CONCLUSION: The existing data suggest that restriction of fructose from the diet could be a useful therapeutic strategy for patients with PCa.


Assuntos
Frutose , Neoplasias da Próstata , Humanos , Masculino , Neoplasias da Próstata/metabolismo , Tomografia por Emissão de Pósitrons , Genitália Masculina , Carbono
20.
Reprod Toxicol ; 124: 108533, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38160783

RESUMO

Human health effects can arise from unregulated manual disassembly of electronic waste (e-waste) and/or hydraulic fracturing fluid spills. There is limited literature on the effects of e-waste and hydraulic fracturing wastewater exposure on the male reproductive system. Thus, this proof-of-concept study begins to address the question of how wastewater from two potentially hazardous environmental processes could affect sperm quality. Therefore, three groups of eight-week-old adult mice were exposed (5 d/wk for 6 wks) via a mealworm (Tenebrio molitor and Zophabas morio) feeding route to either: (1) e-waste leachate (50% dilution) from the Alaba Market (Lagos, Nigeria); (2) West Virginia hydraulic fracturing flowback (HFF) fluid (50% dilution); or, (3) deionized water (control). At 24-hours (hr), 3 weeks (wk), or 9-wk following the 6-wk exposure period, cohorts of mice were necropsied and adverse effects/persistence on the male reproductive system were examined. Ingestion of e-waste leachate or HFF fluid decreased number and concentration of sperm and increased both chromatin damage and numbers of morphological abnormalities in the sperm when compared to control mice. Levels of serum testosterone were reduced post-exposure (3- and 9-wk) in mice exposed to e-waste leachate and HFF when compared to time-matched controls, indicating the long-term persistence of adverse effects, well after the end of exposure. These data suggest that men living around or working in vicinity of either e-waste or hydraulic fracturing could face harmful effects to their reproductive health. From both a human health and economic standpoint, development of prevention and intervention strategies that are culturally relevant and economically sensitive are critically needed to reduce exposure to e-waste and HFF-associated toxic contaminants.


Assuntos
Resíduo Eletrônico , Fraturamento Hidráulico , Poluentes Químicos da Água , Masculino , Humanos , Animais , Camundongos , Resíduo Eletrônico/efeitos adversos , Águas Residuárias/toxicidade , Nigéria , Sêmen/química , Genitália Masculina , Poluentes Químicos da Água/toxicidade
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