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Rev. fac. odontol. Univ. Fed. Bahia ; 35: 7-14, jul.-dez.2007. graf, tab
Artigo em Inglês | BBO - Odontologia | ID: biblio-858071

RESUMO

Porphyromonasgingivalis has been shown to be shown to be one of the most important pathogen in chronic periodontitis development. The aim of this study was to evaluate the correlation among IgA, IgG and IgC and IgG isotype serum levels reactive Porphyromonas gingivalis ATTCC33277 and the clinical periodontal status. Twenty nine periodontitis patients were evaluated according to clinical parameters: probing depth, bleeding on probing, and clinical attachment loss measurements. Humoral immune response was assayed by enzyme linked immunosorbent assay (ELISA). There was no correlation between bleeding on probing (criterion 1) and the evaluated antibodies. Significant positive correlations were found between IgA levels and percentual of sites with clinical attachment loss (CAL) >3mm (criterion 2), percentual of sites with CAL > 5 mm (criterion 3), and percentual of sites with CAL > 3mm associated to probing depth > 4mm and bleeding on probing at the same site (criterion 4) (r=0,311; r=0,336; r=0,358, respectively; p<0,05). There were significant positive correlations between IgG serum levels and criteria 3 and 4 (r=0,400 and r=0,372, respectively; p<0,05), and between IgG1 and criteria 2, 3 and 4 (r=0,333, r=0,323 and r=0,340, respectively; p<0,05). The findings indicate that the antibody response to Porphyromonas gingivalis depends on the periodontal status, determined by clinical parameters


Assuntos
Humanos , Células Produtoras de Anticorpos , Doenças Periodontais
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