Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 83
Filtrar
Mais filtros










Filtros aplicados

Base de dados
Intervalo de ano de publicação
1.
Cir. Esp. (Ed. impr.) ; 97(7): 385-390, ago.-sept. 2019. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-187598

RESUMO

Introducción: El síndrome de obstrucción antroduodenal es una complicación presente en neoplasias avanzadas. Se caracteriza por clínica de obstrucción gastrointestinal alta, con desnutrición progresiva, y se asocia con una disminución de la supervivencia. La derivación mediante gastroyeyunostomía y el tratamiento endoscópico (TE) son las alternativas para el tratamiento del síndrome de obstrucción antroduodenal. El objetivo de este estudio es comparar la eficacia y la supervivencia de ambas. Métodos: Estudio monocentro, observacional y prospectivo de 58 pacientes con síndrome de obstrucción antroduodenal que recibieron tratamiento quirúrgico mediante gastroyeyunostomía con separación gástrica parcial (GYSGP) o TE con prótesis enterales autoexpandibles entre los años 2007-2018. Resultados: A 30 pacientes se les realizó GYSGP y a 28 pacientes TE. La edad media de los pacientes con GYSGP fue significativamente menor (69 vs. 78 años, p = 0,001). No hubo diferencias en cuanto al sexo, el riesgo anestésico-quirúrgico ni la etiología de la neoplasia. Las complicaciones posprocedimiento fueron superiores, aunque no significativas, en el grupo de GYSGP (p = 0,156). El TE se asoció con una menor estancia hospitalaria (p = 0,02) y una mayor precocidad de la tolerancia oral (p < 0,0001). Sin embargo, los pacientes presentaron tasas más altas de obstrucción persistente y recurrente (p = 0,048 y 0,01, respectivamente), unos peores objetivos energéticos (p = 0,009) y una supervivencia menor (9,61 vs. 4,47 meses, p = 0,008). Conclusiones: La GYSGP obtiene una mayor permeabilidad luminal, una mejor tolerancia a la vía oral y una mayor supervivencia. El TE estaría recomendado para pacientes no subsidiarios de la cirugía con un pronóstico limitado a corto plazo


Introduction: Gastric outlet obstruction is a complication of advanced tumors. It causes upper gastrointestinal obstruction, with progressive malnutrition and reduced survival. Currently, gastrojejunostomy or stent placement (SP) are feasible alternatives for the treatment of malignant gastric outlet obstruction. The aim of this study is to compare the efficacy and survival of both techniques. Methods: Single-center observational and prospective study of 58 patients with gastric outlet obstruction who underwent surgical treatment with stomach-partitioning gastrojejunostomy (SPGJ) or SP with self-expanding intraluminal prostheses between 2007 and 2018. Results: Thirty patients underwent SPGJ and 28 SP. The mean age of the first group was significantly lower (69 vs. 78 years, respectively; P = .001). There were no statistically significant differences in terms of sex, perioperative risk or tumor etiology. Postoperative complications were non-significantly higher in the SPGJ group (P = .156). SP was associated with a shorter hospital stay (P = .02) and faster oral intake (P < .0001). However, SP had significantly higher rates of persistent and recurrent obstruction (P = .048 and .01, respectively), poorer energy targets (P=.009) and shorter survival (9.61 vs. 4.47 months; P = .008). Conclusions: SPGJ presents greater luminal permeability, better oral intake and greater survival than SP. SP is preferable for non-surgical patients with a limited short-term prognosis


Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Idoso , Derivação Gástrica/métodos , Obstrução da Saída Gástrica/cirurgia , Stents , Estômago/cirurgia , Derivação Gástrica/efeitos adversos , Obstrução da Saída Gástrica/etiologia , Neoplasias Gastrointestinais/complicações , Complicações Pós-Operatórias , Estudos Prospectivos
3.
Eur. j. anat ; 23(4): 279-287, jul. 2019. ilus, tab
Artigo em Inglês | IBECS | ID: ibc-183002

RESUMO

Hepatobiliary surgeries require extensive knowledge of variations in the origin and branching pattern of arteries extending from the coeliac trunk till the cystic artery. This study was aimed at documenting all possible variations observed in the hepatic arterial tree by meticulous dissection of livers in formalin-fixed cadavers. Twenty formalin-fixed cadavers were meticulously dissected to study the hepatic arterial variations.The common hepatic artery originated from the coeliac trunk, common hepatogastric trunk and common hepatosplenic trunk in 85%, 5%, and 5% respectively. It was absent in 5%. It gave rise to the gastroduodenal and proper hepatic arteries in 85%, trifurcated into gastroduodenal, left and right hepatic arteries in 5%, and left hepatic, right hepatic and cystic arteries in 5%. The proper hepatic artery continued from the common hepatic artery in 85%, and was absent in 15%. It bifurcated into left and right hepatic arteries in 45%, showed a trifurcating pattern in 20% cases, gave rise to 3 separate hepatic branches in 5%, and continued as left hepatic artery alone in 15%. The left hepatic artery originated either from the proper hepatic artery or was a direct continuation of it in 85%, from the common hepatic artery in 10%, and the superior mesenteric artery in 5% cases. It gave rise to the cystic artery in 5%. The right hepatic artery originated from proper hepatic artery in 70%, abdominal aorta in 5%, coeliac trunk in 10%, superior mesenteric artery in 5%, common hepatic artery trifurcation in 10%, and gave rise to the cystic artery in 80%. The cystic artery was absent in 5%. Some of the findings have been reported in other studies, while some were newly reported in the present study. Knowledge of hepatic arterial variations is necessary to prevent complications involving several specialties including interventional radiology, endovascular surgery, chemotherapeutic procedures, hepatobiliary surgery as well as living donor liver transplantation surgeries


No disponible


Assuntos
Humanos , Adolescente , Adulto Jovem , Adulto , Pessoa de Meia-Idade , Variação Anatômica , Artéria Hepática/anatomia & histologia , Cadáver , Estômago/anatomia & histologia , Doenças da Aorta/diagnóstico , Medição da Dor , Artéria Celíaca/anatomia & histologia , Aorta Abdominal/anatomia & histologia
7.
Rev. esp. enferm. dig ; 109(8): 589-591, ago. 2017. ilus
Artigo em Espanhol | IBECS | ID: ibc-165162

RESUMO

Introducción: La duplicación gástrica es una entidad poco frecuente en el adulto que supone solo el 4-8% del total de las duplicaciones gastrointestinales. Consiste en una tumoración quística en el espesor de la pared gástrica rodeada de capa muscular lisa y revestida por mucosa gástrica. Suele ser asintomática, pudiendo presentar síntomas abdominales inespecíficos, así como complicaciones del propio quiste como hemorragias digestivas, úlceras e incluso episodios de pancreatitis. Son difíciles de diferenciar del resto de lesiones submucosas gástricas, ya que pueden simular una tumoración gastrointestinal (GIST) e incluso un quiste mucinoso pancreático. La ecografía endoscópica destaca como método diagnóstico, sin embargo, el diagnóstico definitivo es histológico. Caso clínico: Presentamos el caso de una paciente mujer de 36 años de edad con antecedentes de un episodio de úlcera gástrica perforada 'contenida' que fue manejado de forma conservadora. En la actualidad es diagnosticada de un GIST gástrico, motivo por el cual es intervenida y se le realiza una gastrectomía subtotal laparoscópica con reconstrucción en Y de Roux con buena evolución postoperatoria. Discusión: El diagnóstico histológico definitivo informa de una duplicación gástrica, por lo que el antecedente de úlcera gástrica perforada 'contenida' presentado por la paciente se corresponde con una complicación de la propia duplicación gástrica (AU)


Background: Gastric duplication is an uncommon condition in adults representing only 4-8% of all gastrointestinal duplications. It develops as a cystic growth within the thick gastric wall that is surrounded by a layer of smooth muscle and lined with gastric mucosa. It is usually asymptomatic but may present with nonspecific abdominal symptoms as well as cyst-related complications such as gastrointestinal (GI) bleeding, ulceration and even pancreatitis. They are difficult to distinguish from other gastric submucosal lesions and may also mimic a gastrointestinal tumor (GIST) or mucinous cyst of the pancreas. Endoscopic ultrasound (EUS) is the most widely used diagnostic procedure and histology provides a definitive diagnosis. Case report: We report the case of a 36-year-old female patient with a history of a 'contained' perforated gastric ulcer that was managed conservatively. The patient was diagnosed with a gastric GIST which prompted a laparoscopic subtotal gastrectomy and Roux-en-Y reconstruction with a good postoperative outcome. Discussion: The definitive histological diagnosis was gastric duplication. Thus, the previous diagnosis of a 'contained' perforated gastric ulcer was in fact a complication of the gastric duplication itself (AU)


Assuntos
Humanos , Feminino , Adulto , Tumores do Estroma Gastrointestinal/diagnóstico , Tumores do Estroma Gastrointestinal/patologia , Tumores do Estroma Gastrointestinal , Cistadenocarcinoma Mucinoso/complicações , Cistadenocarcinoma Mucinoso/patologia , Gastrectomia/instrumentação , Estômago/anormalidades , Estômago/patologia , Estômago , Tumores do Estroma Gastrointestinal/cirurgia , Patologia/métodos , Neoplasias Pancreáticas/patologia , Diagnóstico Diferencial
8.
Cir. pediátr ; 30(3): 169-171, jul. 2017. ilus
Artigo em Espanhol | IBECS | ID: ibc-168013

RESUMO

Niña de 4 meses, afecta de una duplicidad gástrica, descubierta como masa abdominal palpable y que desplazaba el bazo y el riñón izquierdo. Mediante laparotomía, se observa una duplicidad gástrica y, tras aspirar una secreción amarillenta, se realiza su exéresis junto con la pared muscular común con la curvatura mayor del estómago y una estructura tubular que, partiendo del polo inferior de la malformación y comunicada con ella, pasaba por encima de la cabeza del páncreas y de la segunda porción duodenal, siguiendo luego un curso posterior hasta insertarse en la base del pilar diafragmático derecho. La histología de esta formación tubular fue compatible con el esófago. Conclusiones. Este tipo de duplicidad no la hemos visto referida en la literatura y refuerza la teoría de que estas malformaciones pudieran ser secundarias a errores de transcripción genéticas de información en la diferenciación del endodermo del tubo digestivo primitivo y de la notocorda (AU)


A 4-month old girl affected by gastric duplication discovered as a palpable abdominal mass displacing the spleen and left kidney. During laparotomy, a yellowish secretion is aspirated and the gastric duplication is excised together with the common muscular Wall of the greater curvature of the stomach. Also excised, a tubular structure starting from the inferior pole of the malformation, and communicating with it, passing superior to the head of the pancreas and the second portion of the duodenum, followed by a posterior course before inserting into the right pillar of the diaphragm. The histology of the tubular formation was compatible with esophagus. Conclusion. This type of duplication has not been reported in the literature and reinforces the theory that these malformations could be secondary to genetic transcription errors, in the differentiation of the endoderm of the primitive digestive tract and the notochord (AU)


Assuntos
Humanos , Feminino , Lactente , Estômago/anormalidades , Estômago/diagnóstico por imagem , Estômago/cirurgia , Laparotomia/métodos , Radiografia Torácica/métodos , Anormalidades Congênitas/diagnóstico , Anormalidades Congênitas/cirurgia
9.
Rev. esp. enferm. dig ; 108(5): 283-284, mayo 2016. ilus
Artigo em Inglês | IBECS | ID: ibc-152771

RESUMO

A man complained of upper abdominal pain and early satiety for one month. An upper gastrointestinal endoscopy showed nothing special. A CT scan of the abdomen was performed, which demonstrated a huge heterogeneous retroperitoneal mass close to the dorsal wall of the stomach and surrounding the abdominal aortic and celiac trunk. The resected specimen suggested that an irregular tumor invaded the dorsal wall of the stomach. Postoperative histological examination confirmed that it was a gastric squamous cell carcinoma (AU)


No disponible


Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Carcinoma de Células Escamosas/complicações , Carcinoma de Células Escamosas/cirurgia , Carcinoma de Células Escamosas , Neoplasias Gástricas/cirurgia , Neoplasias Gástricas , Neoplasias Retroperitoneais/complicações , Neoplasias Retroperitoneais/cirurgia , Neoplasias Retroperitoneais , Estômago/patologia , Estômago/cirurgia , Estômago , Tomografia Computadorizada de Emissão/instrumentação , Tomografia Computadorizada de Emissão/métodos , Tomografia Computadorizada de Emissão , Membrana Celular/patologia , Membrana Celular
10.
Clin. transl. oncol. (Print) ; 17(11): 856-861, nov. 2015. tab, ilus
Artigo em Inglês | IBECS | ID: ibc-143455

RESUMO

Purpose. In high risk gastric and gastroesophageal adenocarcinoma, adjuvant radiochemotherapy with 5-fluorouracil bolus became a standard adjuvant treatment, showing significant improvement in overall survival after surgery, although with substantial toxicity. We explored the efficacy and toxicity of a modified 5-fluorouracil continuous infusion scheme. Methods. We conducted an observational retrospective study in our centre. Gastric/gastroesophageal junction adenocarcinoma patients were treated with a schedule consisting in four infusions of bolus 5-fluorouracil 400 mg/m2 iv with leucovorin 200 mg/m2 iv and 1200 mg/m2 in 46-hour infusion of 5-fluorouracil (D’Gramont scheme), followed by concomitant radiochemotherapy (45 Gy in 25 fractions of 1.8 Gy) with 5-fluorouracil continuously infusion 225 mg/m2/day and four additional infusions of chemotherapy one month after complete radiochemotherapy. Results. Between January 2007 and December 2013, 55 patients received a mean of 3.16 bi-weekly adjuvant infusions followed by 4.6 weeks of continuous treatment concurrent with radiotherapy and 3.72 bi-weekly infusions after radiotherapy treatment. During adjuvant treatment, grade III toxicity was mostly haematologic, while gastrointestinal and cutaneous toxicity was predominant during concurrent treatment. There were no grade IV- or treatment-related deaths during this study. Disease-free survival (DFS) was 79.2 months (56.3–102.1 months), and the 3-year survival rates were 52.7 %. Conclusions. This 5-fluorouracil infusional scheme has an excellent tolerability profile and favourable efficacy results (AU)


No disponible


Assuntos
Feminino , Humanos , Masculino , Fluoruracila/uso terapêutico , Quimioterapia Adjuvante , Adenocarcinoma/diagnóstico , Adenocarcinoma/tratamento farmacológico , Neoplasias Gástricas/tratamento farmacológico , Quimiorradioterapia Adjuvante/métodos , Quimiorradioterapia Adjuvante , Leucovorina/uso terapêutico , Estômago , Estômago/patologia , Estudos Retrospectivos , Análise Estatística , Estimativa de Kaplan-Meier , Intervalos de Confiança
11.
Acta pediatr. esp ; 73(9): 214-217, oct. 2015. tab
Artigo em Espanhol | IBECS | ID: ibc-145738

RESUMO

El síndrome de dumping (SD) es un conjunto de síntomas gastrointestinales y vasomotores que se produce como consecuencia de la cirugía gástrica. En pediatría se ha descrito fundamentalmente tras la cirugía antirreflujo. El diagnóstico es clínico, pero la sobrecarga oral de glucosa puede ser de utilidad si existen dudas. Se presentan los casos de 8 pacientes afectados de SD, 6 varones y 2 mujeres, con edades comprendidas entre 13 meses y 9 años en el momento del diagnóstico. Cuatro pacientes tenían como enfermedad de base una atresia de esófago intervenida, 2 un reflujo gastroesofágico, 1 una hernia diafragmática congénita y 1 un tumor gástrico. Todos fueron sometidos previamente a algún tipo de cirugía gástrica. En 7 de ellos se realizó una funduplicatura, y en 4 una piloroplastia. Todos los pacientes tenían clínica de SD temprano, y 6 asociaban clínica de SD tardío. En todos ellos se realizó una sobrecarga oral de glucosa, que confirmó el diagnóstico. El tratamiento dietético fue efectivo en 7 pacientes, y 1 paciente precisó además tratamiento con acarbosa. El tratamiento dietético es efectivo en la mayoría de los pacientes con SD (AU)


Dumping syndrome (DS) is a condition where gastrointestinal and vasomotor symptoms happen as a consequence of gastric surgery. In pediatrics it has been described primarily after anti-reflux surgery. The diagnosis is clinical, but the oral glucose tolerance test can be useful if there are doubts. We present the cases of 8 patients with DS, 6 men and 2 women, aged between 13 months and 9 years old. Four patients had atresia of esophagus, 2 gastroesophageal reflux disease, 1 patient a congenital diaphragmatic hernia, and 1 a gastric tumor. All were treated with gastric surgery. In 7 of them fundoplication was performed, and in 4 piloroplastia. All patients had early dumping, and 6 had late dumping. In all patients oral glucose tolerance test confirmed the diagnosis. Dietary treatment was effective in 7 patients; 1 patient also required treatment with acarbose. Dietary treatment is effective in most patients with DS (AU)


Assuntos
Humanos , Masculino , Feminino , Criança , Lactente , Pré-Escolar , Adolescente , Estômago/cirurgia , Complicações Pós-Operatórias , Procedimentos Cirúrgicos do Sistema Digestório/efeitos adversos , Fundoplicatura/efeitos adversos , Glucose/uso terapêutico , Edulcorantes/uso terapêutico , Dietoterapia
12.
Nutr. hosp ; 32(3): 1180-1183, sept. 2015. ilus
Artigo em Inglês | IBECS | ID: ibc-142483

RESUMO

Crocodiles are susceptible to infection with a wide array of external and internal gastrointestinal helminths, yet little is known on the histopathology following infection or the effects of these parasites. The present study was aimed at evaluating the impact of infection by Ortleppascaris sinensis (Nematoda: Ascaridoidea) on the stomach of captive Alligator sinensis. The histological examination of the stomach revealed presence of superficial ulcer in mucous layer and granulomatous inflammation in submucous layer at entire gastric walls of the Alligator sinensis. Our findings also confirm that development of Ortleppascaris sinensis is in close association with the wall of the stomach (AU)


Los cocodrilos son susceptibles a la infección con una amplia gama de helmintos gastrointestinales externos e internos; sin embargo, poco se sabe sobre la histopatología tras la infección o los efectos de estos parásitos. El presente estudio pretende evaluar el impacto de la infección por Ortleppascaris sinensis (Nematodos: Ascaridoidea) sobre el estómago del Alligator sinensis en cautividad. El examen histológico del estómago reveló la presencia de úlcera superficial en la capa mucosa e inflamación granulomatosa en la capa submucosa del conjunto de las paredes gástricas del Alligator sinensis. Nuestros resultados confirman también que el desarrollo de Ortleppascaris sinensis está estrechamente relacionado con la pared del estómago (AU)


Assuntos
Animais , Estômago/ultraestrutura , Nematoides/isolamento & purificação , Infecções por Nematoides/diagnóstico , Úlcera Gástrica/microbiologia , Histocitoquímica , Jacarés e Crocodilos
17.
Cuad. med. forense ; 20(1): 44-47, ene.-mar. 2014. tab
Artigo em Espanhol | IBECS | ID: ibc-125555

RESUMO

Los materiales de sutura pueden ocasionar alteraciones o artefactos que en ocasiones nos plantearán dudas de diagnóstico diferencial con procesos tumorales o de otra naturaleza. Durante la realización de una autopsia el patólogo puede hallar una masa localizada en un órgano, tejido o vaso, que le puede llevar a pensar en un proceso tumoral, y un estudio histopatológico sorprenderlo con el diagnostico de reacción tisular por material de sutura (AU)


Suture materials can cause changes or artefacts that can occasionally raise doubts in the differential diagnosis of tumour processes or of any other nature. During the performance of an autopsy, the forensic pathologist may find a mass in organs, tissues or vessels that may lead him to think about a tumoral process, and the histopathological diagnosis surprise him with tissue reaction caused by suture material (AU)


Assuntos
Humanos , Masculino , Idoso de 80 Anos ou mais , Suturas/efeitos adversos , Corpos Estranhos/diagnóstico , Neoplasias/diagnóstico , Fibrose/etiologia , Estômago/patologia , Diagnóstico Diferencial , Achados Incidentais , Complicações Pós-Operatórias/diagnóstico , Autopsia/métodos
18.
Clin. transl. oncol. (Print) ; 15(6): 472-476, jun. 2013. tab, ilus
Artigo em Inglês | IBECS | ID: ibc-127390

RESUMO

BACKGROUND: Surgical resection remains the principal treatment for advanced gastric cancer. However, one of the difficulties in radical D2 lymphadenectomy is the identification of the vascular abnormalities around the stomach, especially abnormal hepatic artery. The hepatic artery arising from the superior mesenteric artery shows great variations, and whether or not the lymphatic tissues around the abnormal artery should be dissected is still controversial. METHOD: Eighty-six gastric cancer patients who underwent radical D2 lymphadenectomy by the same surgeon in our department in the past 2 years were included in this study. All patients underwent multislice spiral computed tomography angiography for preoperative evaluation of the abnormal hepatic artery arising from the superior mesenteric artery. Postoperative immunohistochemistry of the lymphoid tissues around the abnormal hepatic artery was performed using CK20 and CEA antibodies to determine the occurrence of lymph node micrometastasis around the abnormal artery. RESULTS: In our study, we found 14 cases with an abnormal hepatic artery arising from the superior mesenteric artery. The hepatic artery ran in front of the pancreas in 1 case and behind the pancreas in 13 cases. Immunohistochemical analyses revealed no micrometastasis in the lymphoid tissues surrounding the abnormal artery. CONCLUSIONS: Abnormal hepatic arteries arising from the superior mesenteric artery can be classified into pre-pancreas and post-pancreas types. Lymph nodes around the abnormal artery may not need to be dissected in radical D2 lymphadenectomy (AU)


Assuntos
Humanos , Masculino , Feminino , Neoplasias Gástricas/induzido quimicamente , Neoplasias Gástricas/tratamento farmacológico , Neoplasias Gástricas/metabolismo , Neoplasias Gástricas/diagnóstico , Estômago/efeitos da radiação , Linfonodos/efeitos da radiação
19.
Enferm. infecc. microbiol. clín. (Ed. impr.) ; 31(3): 130-135, mar. 2013. ilus, tab
Artigo em Inglês | IBECS | ID: ibc-110859

RESUMO

Introduction Helicobacter pylori adheres to various components of the human saliva. Therefore, the objective of this research was to simultaneously detect H. pylori in saliva and in gastric biopsy, and to determine the agreement between the vacA genotypes in both saliva and gastric biopsy. Materials and methods A total of 162 patients with chronic gastritis and 34 with gastric ulcer were studied, and saliva and biopsy samples were collected from each patient. H. pylori DNA was detected by conventional PCR and nested PCR was used for vacA genotyping. Result sIn 24% of the patients (47/196) H. pylori DNA was found in saliva and in biopsy; 52.5% (103/196) were salivanegative/biopsypositive and 6.6% (13/196) were salivapositive/biopsynegative. In either or both H. pylori vacAs1m1 or s1m2 genotypes were detected in saliva in 41.5% of the patients with chronic gastritis. Forty-seven percent had >1 genotype, and the s1m1/s1m2 combination was found in 36% of them. H. pylori vacAs1m1 and s1m2 were also found in the saliva and biopsy of patients with gastric ulcer. The genotypes found in saliva and biopsy of the same patient had 51.1% agreement. In 27.6% of the 47 patients salivapositive/biopsypositive two genotypes were found in saliva, and one or both in the stomach. Conclusions The s1m1/s1m2 genotypes, alone or together, are found simultaneously in saliva and gastric biopsy of the same patient. These results suggest that H. pylori reaches the oral cavity by various ways, and that saliva can be the transmitting and re-infecting vector (AU)


Introduccion Helicobacter pylori (H. pylori) se adhiere a diversos componentes de la saliva humana, por ello, el objetivo de esta investigación fue detectar H. pylori en saliva y biopsia gástrica y determinar la concordancia entre los genotipos vacA encontrados en saliva y estómago del mismo paciente. Material y métodos Se estudiaron 162 pacientes con gastritis crónica y 34 con úlcera gástrica. De cada paciente se obtuvo una muestra de saliva y biopsia gástrica. El ADN de H. pylori se detectó por PCR convencional y la genotipificación de vacA se hizo por PCR anidada. Resultados En el 24% (47/196) de los pacientes se encontró ADN de H. pylori en saliva y biopsia; el 52,5% (103/196) fueron salivanegativos/biopsiapositivos y el 6,6% (13/196) resultaron salivapositivos/biopsianegativos. En 41,5% de los pacientes con gastritis crónica, se encontró H. pylori vacA s1m1, s1m2 o ambos en saliva. El 47,2% tenían>1 genotipo y en 36% de esos se encontró la combinación s1m1/s1m2. H. pylori vacA s1m1 y s1m2 también se encontró en saliva y biopsia de pacientes con úlcera. El acuerdo entre los genotipos encontrados en saliva y biopsia de los mismos pacientes fue del 51,1%. En el 27,6% de los 47 pacientes salivapositivos/biopsiapositivos se encontraron 2 genotipos en saliva, y uno o los 2 también se encontraron en estómago. Conclusiones Los genotipos s1m1/s1m2 solos o coexistiendo se encuentran simultáneamente en saliva y biopsia de los mismos pacientes. Los resultados sugieren que H. pylori alcanza la cavidad oral por diversas vías y la saliva puede servir de vehículo para la transmisión y reinfección (AU)


Assuntos
Humanos , Helicobacter pylori/isolamento & purificação , Infecções por Helicobacter/microbiologia , Boca/microbiologia , Gastrite/microbiologia , Úlcera Gástrica/microbiologia , Estômago/microbiologia , Saliva/microbiologia , Genótipo
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA