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1.
Nutr. hosp ; 36(4): 905-911, jul.-ago. 2019. tab, graf
Artigo em Inglês | IBECS | ID: ibc-184717

RESUMO

Introduction: therapeutic lifestyles changes including frequent consumption of legumes have resulted in improved metabolic control and decreased blood pressure in type 2 diabetes-mellitus (T2DM) patients. Objective: this was a quasi-experimental-28-week crossover-study that assessed the effect of daily consumption of the legume Lupinus mutabilis (LM) on metabolic control of T2DM patients under hypoglycemic oral treatment. Material and methods: we recruited 79 adult male and female patients that were followed for 14-weeks without LM consumption and then received increasing doses of a LM-based-snack for other 14-weeks. Results: there was a significant decrease in blood pressure and a significant increase in HDL-cholesterol by the end of the study period. While patients with A1C concentrations > 8 and ≤ 10 did not significantly improve their metabolic control, patients with serum A1C concentrations ≤ 8.0% reduced significantly their A1C after the intervention and 71% achieved a target concentration of 6.5%. Conclusion: patients with T2DM could benefit with the addition of LM-snack to their conventional treatment


Introducción: los cambios recomendados sobre los estilos de vida, incluido el consumo frecuente de leguminosas, han resultado en un mejor control metabólico y disminución de la presión arterial en pacientes con diabetes mellitus tipo 2 (DMT2). Objetivo: este fue un estudio casi experimental cruzado de 28 semanas que evaluó el efecto del consumo diario de la leguminosa Lupinus mutabilis Sweet (LM) en el control metabólico de pacientes con DMT2 con tratamiento oral hipoglucemiante. Material y métodos: inicialmente se reclutaron 79 pacientes adultos, hombres y mujeres, que fueron seguidos durante 14 semanas sin consumo de LM y luego recibieron dosis crecientes de un tentempié de LM durante otras 14 semanas. Resultados: se observó una disminución significativa en la presión arterial y un aumento significativo en el colesterol-HDL después del consumo de LM. Mientras que los pacientes con concentraciones de A1C sérica > 8 y ≤ 10 no mejoraron significativamente su control metabólico, los pacientes con concentraciones séricas de A1C ≤ 8,0% redujeron significativamente su A1C después de la intervención y el 71% de estos pacientes llegó a la meta de tratamiento ≤ 6,5%. Conclusión: los pacientes con DMT2 podrían beneficiarse con la adición de un tentempié de LM a su tratamiento convencional


Assuntos
Humanos , Masculino , Feminino , Adulto , Diabetes Mellitus Tipo 2/dietoterapia , Lupinus , Resultado do Tratamento , Fabaceae , Lanches , Fitoterapia , Valor Nutritivo , Hipoglicemiantes/administração & dosagem , HDL-Colesterol/metabolismo , Pressão Arterial/efeitos dos fármacos , Gluconeogênese , Índice Glicêmico , Equador , Antropometria , Proteínas na Dieta , Sementes
2.
Int. microbiol ; 22(1): 91-101, mar. 2019. graf, tab
Artigo em Inglês | IBECS | ID: ibc-184817

RESUMO

A novel exopolysaccharide (EPS) was produced by a bacterium which was isolated from Psophocarpus tetragonolobus (L) D.C. and identified as 99% Rhizobium tropici SRA1 by 16S rDNA sequencing. The flocculating performances along with emulsifying activity began simultaneously with the growth and the production of EPS and reached its utmost at 28 h. EPS was purified via chilled ethanol precipitation followed by dialysis and lyophilization. The existence of hydroxyl, methoxyl, and carboxylic functional groups were confirmed by Fourier transform infrared (FT-IR) spectrum. EPS was found to be compose of 82.44% neutral sugar and 15.93% uronic acid. The average molecular weight of the exopolysaccharide was estimated as ~1.8×105. Gas-liquid chromatography indicated the presence of glucose and galactose at a molar ratio of 3:1 in EPS. In the pH range of 3-5 with EPS dosage of 15 mg/l at 30 °C, cation-independent flocculation greater than 90% was observed. Emulsification indices (E24) of EPS were observed as 86.66%, 83.33%, 76.66%, and 73.33% with olive oil, kerosene, toluene, and n-hexane respectively. Biosorption of Cu K [45.69 wt%], Cu L [05.67 wt%], Co K [15.58 wt%], and Co L [11.72 wt%] by EPS was confirmed by energy-dispersive X-ray spectroscopy (EDS). This report on the flocculating, emulsifying, and metal sorption properties of EPS produced by R. tropici SRA1 is unique in the literature


No disponible


Assuntos
Fabaceae/microbiologia , Metais/metabolismo , Polissacarídeos Bacterianos/metabolismo , Rhizobium tropici/isolamento & purificação , Rhizobium tropici/classificação , Rhizobium tropici/metabolismo , Cromatografia Gasosa , Cromatografia Líquida , Análise por Conglomerados , DNA Bacteriano , DNA Ribossômico , Análise de Sequência de DNA , Ácidos Urônicos/análise , Espectroscopia de Infravermelho com Transformada de Fourier , Açúcares/análise
3.
Nutr. hosp ; 36(1): 118-124, ene.-feb. 2019. tab
Artigo em Espanhol | IBECS | ID: ibc-183197

RESUMO

Introducción: la capacidad antioxidante total (TAC) se considera un indicador confi able del contenido de antioxidantes de la dieta y se asocia a menor riesgo de padecer enfermedades crónicas. Objetivos: estimar la TAC asociada a la ingesta de alimentos vegetales en adultos jóvenes de área urbana de Paraguay. Métodos: se aplicaron tres recordatorios de ingesta de 24 horas en una muestra aleatoria de 190 estudiantes universitarios en Asunción-Paraguay, entre 2012 y 2014, para determinar la ingesta de vegetales, su TAC asociada y el contenido de antioxidantes específi cos empleando las bases de datos del Ministerio de Agricultura de Estados Unidos (USDA). Resultados: la media de ingesta total de vegetales y la TAC asociada fue 262 g/d y 3093 expresada en capacidad de absorción de radicales de oxígeno (ORAC), distribuida en 76,9 g/d de frutas (1.624 ORAC), 57,9 g/d de jugos de frutas (444 ORAC), 47,8 g/d de hortalizas crudas (314 ORAC), 75,1 g/d de hortalizas cocidas (604 ORAC) y 4,5 g/d de legumbres (106 ORAC). La ingesta media de vitamina C fue de 73,2 mg/d y la de flavonoides y carotenoides fue de 26,4 mg/d y 4848 μg/d, respectivamente. Conclusiones: la ingesta total y por grupo de vegetales fue inferior a lo recomendado por la Organización Mundial de la Salud (OMS). La TAC asociada a la ingesta de vegetales en la dieta fue inferior a la reportada por otros estudios. La mayor contribución a la ingesta total y a la TAC correspondió a las frutas y la mínima, a las legumbres. Los resultados revelan la necesidad de incrementar la ingesta de vegetales por encima de 400 g/d, incluyendo alimentos ricos en compuestos antioxidantes


Introduction: total antioxidant capacity (TAC) is considered as a reliable indicator of the antioxidant content of the diet and it is associated to a reduced risk of chronic disease. Objectives: to estimate the TAC related to the intake of fruits and vegetables in young adults from urban areas of Paraguay. Methods: a minimum of three 24-hour dietary recalls were recorded from a random sample of 190 university students in Asunción-Paraguay, between 2012 and 2014, to determine the intake of fruits and vegetables, their TAC value and the contents of specifi c antioxidants, applying the United States Department of Agriculture (USDA) data bases. Results: the mean value of the total vegetable intake and its TAC value were 262 g/d and 3,093 oxygen radical absorbance capacity (ORAC), respectively, distributed as follows: 76.9 g/d from fruits (1,624 ORAC), 57.9 g/d from fruit juices (444 ORAC), 47.8 g/d from raw vegetables (314 ORAC), 75.1 g/d from cooked vegetables (604 ORAC) and 4.5 g/d from legumes (106 ORAC). The mean C-vitamin intake was 73.2 mg/d, and fl avonoids and carotenoids were present with 26.4 mg/d and 4,848 μg/d, respectively. Conclusions: the total fruit and vegetable intake, distributed by groups of foods, was low, considering the World Health Organization (WHO) fruit and vegetable recommendation. The TAC value related to vegetable intake was lower than those reported in other studies. The major contribution to both intake and antioxidants was provided by fruits, and the minor by legumes. Our results reveal the need to increase the vegetable intake above 400 g/d, including antioxidant-rich food sources


Assuntos
Humanos , Masculino , Feminino , Adolescente , Adulto Jovem , Adulto , Antioxidantes/análise , Frutas , Verduras , Dieta , Fabaceae , Estado Nutricional , Paraguai , Estudantes , Universidades , População Urbana
4.
Nutr. clín. diet. hosp ; 37(2): 98-106, 2017. graf, tab
Artigo em Espanhol | IBECS | ID: ibc-165439

RESUMO

Objetivo: En este trabajo se estudió el efecto de la ingesta crónica de harina de caraotas negras y harina de avena sobre la actividad de las disacaridasas intestinales en ratas. Metodología: 15 ratas Sprague Dawley, con un peso inicial promedio de 85g se dividieron en tres grupos, un grupo control sin fibra, un grupo alimentado con harina de caraotas negras y un grupo con harina de avena por 21 días. Los animales fueron sacrificados, el intestino delgado se dividió en tres porciones (proximal, media, y distal), y se obtuvo un homogenato por raspado de la mucosa. Resultados: La actividad de las disacaridasas se estimó mediante la determinación de glucosa por un método enzimático con peroxidasa. El orden de actividad enzimática fue Maltasa > Sacarasa > Lactasa, obteniéndose una mayor actividad en la región intestinal media para cada disacaridasa. El consumo de harina de caraotas produjo un incremento significativo en la actividad de la maltasa y sacarasa, en esta última, de más de un 100% en relación con el control. La suplementación de las dietas con avena produjo una disminución de la actividad de la sacarasa de un 40% y no produjo ningún efecto sobre la actividad de la maltasa y lactasa. Conclusiones: Estos resultados señalan que el efecto que produce la ingesta crónica de fibra dietética sobre la actividad de las disacaridasas intestinales no se puede generalizar, cada enzima reacciona de manera particular frente a cada tipo de fibra, y puede variar además, según el segmento del intestino delgado estudiado (AU)


Objective: In this work was studied the effect of chronic intake of black beans flour and oat flour on the activity of the intestinal disaccharidases in rats. Methodology: 15 Sprague Dawley rats, with an initial average weight of 85g were distributed, into three groups, a fiber free control group, a group fed with black beans flour and a group with oat flour for 21 days. Then, the rats were sacrificed and the small intestine was divided into three sections (proximal, medial, and distal). The homogenate was obtained by scraping the mucosa of each section. Results: The activity of the disaccharidases was estimated by the glucose determination using peroxidase enzymatic method. The order of enzyme activity was maltase> Sucrase > lactase, obtaining a greater activity in the middle intestinal region for each disaccharidase. The consumption of beans flour produced a significant increase in the activity of maltase and sucrase, the latter, with more than 100% in relation to control. Diets with oats supplementation resulted in a decrease of 40% sucrase activity and did not produce any effect on the activity of maltase and lactase. Conclusions: These results indicate that the effect of chronic dietary fiber intake on the activity of intestinal disaccharidases cannot be generalized, each enzyme reacts in a particular way to each type of fiber and may also vary according to the segment of the small intestine (AU)


Assuntos
Animais , Ratos , Avena/enzimologia , Dissacaridases/metabolismo , Fabaceae/enzimologia , Fibras na Dieta/metabolismo , Farinha , alfa-Glucosidases/análise , Sacarase/análise , beta-Galactosidase/metabolismo , Modelos Animais
6.
Rev. iberoam. micol ; 32(4): 269-272, oct.-dic. 2015. ilus
Artigo em Inglês | IBECS | ID: ibc-143448

RESUMO

Background. Cryptococcus gattii is a pathogenic basidiomycetous yeast that is emerging in temperate climate zones worldwide. C. gattii has repetitively been isolated from numerous tree species. Ongoing environmental sampling and molecular characterization is essential to understand the presence of this primary pathogenic microorganism in the Mediterranean environment. Aims. To report the first isolation of the rare C. gattii genotype AFLP7/VGIV from the environment in Europe. Methods. Samples were collected from woody debris of carob trees (Ceratonia siliqua) and olive trees (Olea europaea) in El Perelló, Tarragona, Spain. Cryptococcus species were further characterized by using URA5-RFLP, MALDI-TOF, AFLP and MLST. The antifungal susceptibility profile to amphotericin B, 5-fluorocytosine, fluconazole, itraconazole, posaconazole and voriconazole was determined using Sensititre Yeast One and E-test. Results. Cultures from one carob tree revealed the presence of ten Cryptococcus-like colonies. One colony was identified as C. gattii, and subsequent molecular characterization showed that it was an α mating-type that belonged to the rare genotype AFLP7/VGIV. Antifungal susceptibility testing showed values within the range of sensitivity described for other isolates of the same genotype and within the epidemiological cutoff values for this species. Conclusions. The isolation of the rare C. gattii genotype AFLP7/VGIV in Spain is the first report in the European environment, implying the possible presence in other regions of the Mediterranean area, and underlines that clinicians must be aware for C. gattii infections in healthy individuals (AU)


Antecedentes. Cryptococcus gattii es una levadura perteneciente a los basidiomicetos y considerada un patógeno emergente en climas templados. C. gattii se ha aislado en un gran número de especies de árboles en todo el mundo. El muestreo medioambiental y la caracterización molecular de C. gattii es esencial para entender la presencia de este patógeno primario en el entorno de la cuenca mediterránea. Objetivos. Comunicar la presencia del raro genotipo AFLP7/VGIV de C. gattii en el medioambiente en Europa. Métodos. Se tomaron muestras de detritus de algarrobos (Ceratonia siliqua) y olivos (Olea europaea) en las afueras de El Perelló (Tarragona, España). La colonia de C. gattii aislada se sometió a análisis mediante URA5-RFLP, MALDI-TOF, AFLP y MLST. Se llevó a cabo un estudio de sensibilidad in vitro a la anfotericina B, 5-fluorocitosina, fluconazol, itraconazol, posaconazol y voriconazol mediante las pruebas comerciales Sensititre Yeast One® y E-test®. Resultados. De una de las muestras de un algarrobo se aislaron 10 colonias susceptibles de ser Cryptococcus. Una de ellas fue estudiada e identificada como C. gattii, y su subsecuente caracterización molecular mostró que se trataba de un tipo sexual α y que pertenecía al raro genotipo AFLP7/VGIV. El estudio de la sensibilidad a los antifúngicos mostró valores similares a los de otras cepas del mismo genotipo y dentro del rango de valores de corte epidemiológicos para la especie. Conclusiones. El aislamiento en España de C. gattii con el genotipo AFLP7/VGIV es el primero descrito en el medioambiente en Europa; podría encontrarse también en otros países de la cuenca mediterránea, donde debería tenerse un especial cuidado por la posibilidad de infección en individuos no inmunodeprimidos (AU)


Assuntos
Fabaceae/microbiologia , Doenças das Plantas/microbiologia , Cryptococcus gattii/isolamento & purificação , Técnicas de Genotipagem/métodos , Testes de Sensibilidade Microbiana , Polimorfismo de Fragmento de Restrição/genética , Impressões Digitais de DNA/métodos
7.
Nutr. hosp ; 32(5): 2126-2135, nov. 2015. ilus, tab
Artigo em Inglês | IBECS | ID: ibc-145540

RESUMO

Introduction: fibromyalgia is a chronic disease characterized by generalized pain, stiffness, poor physical conditioning, non-restorative sleep and poor health-related quality of life. Ganoderma lucidum a type of mushroom that has demonstrated several benefits in different populations. Ceratonia siliqua is a natural therapy rich in antioxidants with potential benefits on health. Objective: to evaluate the effects of 6-week treatment of Ganoderma lucidum and Ceratonia siliqua on physical fitness in patients suffering from fibromyalgia. Methods: sixty-four women with fibromyalgia participated in the study. They took 6 g of Ganoderma lucidum or Ceratonia siliqua per day for 6 weeks. Different fitness tests were selected in order to evaluate functional capacity. Results: after the 6-week treatment period, Ganoderma lucidum significantly improved aerobic endurance, lower body flexibility, and velocity (p < .05). No significant improvement in any physical test was observed in the Ceratonia siliqua group. Discussion and conclusion: Ganoderma lucidum may improve physical fitness in women with fibromyalgia, whereas, Ceratonia siliqua seemed to be ineffective at increasing physical fitness. These results may indicate that Ganoderma lucidum might be a useful dietary supplement to enhance physical performance of the patients suffering from fibromyalgia (AU)


Introducción: la fibromialgia es una enfermedad crónica caracterizada por dolor crónico general, rigidez, condición física pobre, sueño no reparador y mala calidad de vida relacionada con la salud. Ganoderma lucidum es un tipo de hongo que ha demostrado tener diferentes beneficios en diversas poblaciones. La harina de algarrobo (Ceratonia siliqua) es una fuente natural de antioxidantes con potenciales beneficios para la salud. Objetivo: evaluar los efectos sobre la condición física en mujeres con fibromialgia de un tratamiento de seis semanas con Ganoderma lucidum y compararlos con los de un tratamiento con Ceratonia siliqua. Métodos: sesenta y cuatro mujeres con fibromialgia participaron en el estudio. Se hicieron dos grupos, el primer grupo tomó 6 g diarios de Ganoderma lucidum, mientras que el segundo tomó 6 g diarios de Ceratonia siliqua. Se evaluó la condición física mediante diferentes test físicos validados. Resultados: después de seis semanas de tratamiento, Ganoderma lucidum mejoró significativamente la resistencia aeróbica, la flexibilidad del miembro inferior y la velocidad (p < 0,05). Por otro lado, Ceratonia siliqua no mejoró la condición física. Discusión y conclusiones: Ganoderma lucidum puede mejorar la condición física en mujeres con fibromialgia, mientras que Ceratonia siliqua parece no ser efectivo para este propósito. Estos resultados pueden indicar que 6 g diarios de Ganoderma lucidum podrían ser un suplemento útil para mejorar la condición física en esta población (AU)


Assuntos
Humanos , Reishi , Fibromialgia/tratamento farmacológico , Dor Crônica/tratamento farmacológico , Manejo da Dor/métodos , Fabaceae , Condicionamento Físico Humano/fisiologia , Força Muscular
8.
Allergol. immunopatol ; 43(2): 196-202, mar.-abr. 2015. tab
Artigo em Inglês | IBECS | ID: ibc-134687

RESUMO

In the past few decades, the prevalence of allergic diseases has deeply increased, with a key role played by food allergies. Legumes seem to play a major role towards the overall increase in the scenario of food allergy, since they are an appreciated source, consumed worldwide, due to their high protein content, variable amounts of lipids and for the presence of vitamins. In literature there are numerous descriptions of adverse reactions after ingestion of uncooked and cooked legumes. Nevertheless, cases of allergic reactions induced by inhaling vapours from cooking legumes have rarely been described. Herein the authors report an update of the literature data on allergic reactions caused by legume steam inhalation, underlying the possible pathogenic mechanism of these atopic events and the knowledge of literature data in paediatric age. The importance of this review is the focus on the clinical aspects concerning legume vapour allergy, referring to literature data in childhood (AU)


No disponibl


Assuntos
Humanos , Masculino , Feminino , Hipersensibilidade Alimentar/complicações , Hipersensibilidade Alimentar/diagnóstico , Fabaceae/classificação , Rinite Alérgica Sazonal/diagnóstico , Anafilaxia/diagnóstico , Hipersensibilidade Alimentar/metabolismo , Hipersensibilidade Alimentar/prevenção & controle , Fabaceae/toxicidade , Rinite Alérgica Sazonal/complicações , Anafilaxia/complicações
9.
Nutr. hosp ; 31(3): 1012-1019, mar. 2015. tab
Artigo em Inglês | IBECS | ID: ibc-134392

RESUMO

Background: Countries following the traditional Mediterranean Diet, particularly Southern European countries, have lower prostate cancer incidence and mortality compared to other European regions. The beneficial effect has been attributed to a specific eating pattern. Objective: The purpose of this review is to examine the evidence to date on the effects of adherence to a Mediterranean Diet on prostate cancer risk; and to identify which elements of the Mediterranean diet are likely to protect against prostate cancer. Methods: The search for articles came from extensive research in the following databases: PubMed, Scopus and Web of Science. We used the search terms 'Mediterranean diet', 'adherence', 'fruit and vegetable', 'olive oil', 'fish' 'legume', 'cereal' 'alcohol' 'milk', 'dairy product', 'prostate cancer', and combinations, such as 'Mediterranean diet and prostate cancer' or 'Olive oil and prostate cancer'. Results: There is strong evidence supporting associations between foods that are typical of a Mediterranean eating pattern and reduced prostate cancer risk. However, there are few studies that have assessed the effect of the Mediterranean diet on cancer prostate incidence. Recent data do not support associations to adherence to a Mediterranean Diet and risk of prostate cancer or disease progression. However, Mediterranean eating pattern after diagnosis of nonmetastatatic cancer was associated with lower overall mortality. Conclusion: Further large-scale studies are required to clarify the effect of Mediterranean diet on prostate health, in order to establish the role of this diet in the prevention of prostate cáncer (AU)


Introducción: Los países del sur de Europa, tienen una menor incidencia y mortalidad por cáncer de próstata en comparación con otras regiones europeas. Este efecto beneficioso se ha atribuido a un patrón de alimentación específica. Objetivo: El objetivo de esta revisión es examinar la evidencia sobre los efectos de la adhesión a la dieta mediterránea en el riesgo de cáncer de próstata; e identificar que componentes de la dieta mediterránea protegen contra el cáncer de próstata. Métodos: Se realizó una búsqueda en la literatura científica utilizando las siguientes base de datos: PubMed, Scopus and Web of Science. Utilizamos los términos de búsqueda 'dieta mediterránea', 'adhesión', 'frutas y verduras', 'aceite de oliva', 'pescado' 'legumbres', 'cereal' 'alcohol' 'leche', 'producto lácteo', 'cáncer de próstata', y combinaciones, tales como 'dieta mediterránea y cáncer de próstata' o 'aceite de oliva y cáncer de próstata'. Resultados: Existe una fuerte evidencia que soporta una asociación entre alimentos que son típicos de un patrón de alimentación mediterránea y un menor riesgo de cáncer de próstata. Sin embargo, son pocos los estudios que han evaluado el efecto de la dieta mediterránea sobre la incidencia del cáncer de próstata. Los datos recientes no apoyan una asociación entre el seguimiento de este tipo de dieta y el riesgo de cáncer de próstata o su progresión. Sin embargo, un patrón de alimentación mediterránea después del diagnóstico de cáncer no metastásico se ha asociado con una disminución de la mortalidad global. Conclusión: Se requieren más estudios a gran escala para aclarar el efecto de la dieta mediterránea sobre la salud prostática, con el fin de establecer su papel en la prevención de cáncer de próstata (AU)


Assuntos
Humanos , Masculino , Dieta Mediterrânea/estatística & dados numéricos , Neoplasias da Próstata/prevenção & controle , Substâncias Protetoras/análise , Prevenção Primária/organização & administração , Gorduras Vegetais , Produtos Pesqueiros , Grão Comestível , Fabaceae
10.
Nutr. hosp ; 31(3): 1438-1443, mar. 2015. ilus, tab
Artigo em Inglês | IBECS | ID: ibc-134449

RESUMO

Background: The food environment can have an important influence on the availability of and access to food, which plays a significant role in the health of individuals. The goal of this study was to compare the consumption of fruits, legumes and vegetables (FLV) by adults and the availability of food stores in the context of socioeconomic and geographic space connected to basic health units in a Brazilian capital city. Methods: The study was developed from information obtained through the Risk Factors Surveillance for Non-Communicable Diseases Prevention by Telephone Survey (VIGITEL), using samples from Belo Horizonte from the years 2008 to 2010. A total of 5611 records were geocoded based on the postal code. A score was created based on the weekly and daily frequency of FLV intake of individuals. The coverage area of basic health units was used as a neighborhood unit. Georeferenced data on food stores in the city and neighborhood income were used. Results: As neighborhood income increased, there was an increase in the distribution of food establishments for all of the studied categories. The highest FLV intake scores were observed in areas with higher income levels. Conclusion: The highest concentration of food stores, regardless of supply quality, was observed in geographic areas with higher purchasing power and in those where there was a greater concentration of other types of businesses and services, a different pattern from that found in other countries (AU)


Antecedentes: El ambiente alimentar puede tener una influencia importante en la disponibilidad y el acceso a ellos, éste desempeña un papel importante en la salud de las poblaciones. El objetivo de este estudio fue comparar el consumo de frutas, legumbres y hortalizas (FLV) de adultos y la disponibilidad de las tiendas de alimentos en el contexto del espacio socioeconómico y geográfico en el territorio de las unidades básicas de salud en una capital brasileña. Métodos: El estudio se desarrolló a partir de la información obtenida a través de la Vigilancia de Factores de Riesgo para Enfermedades no Transmisibles Prevención de Encuesta Telefónica (VIGITEL), utilizando muestras de la ciudad de Belo Horizonte en los años de 2008 a 2010. Un total de 5.611 registros fueron geo-codificados usando el código postal. Una puntuación fue creada en base a la frecuencia semanal y diario del consumo de FLV . El área de las unidades básicas de salud se utilizó como unidad vecinal. Se utilizaron los datos geo-referenciados de los comercios de venta de comida en la ciudad y el barrio. Resultados: A medida que aumentaba la renta del barrio, hubo un aumento en la distribución de los establecimientos de comida e bebidas para todas las categorías estudiadas. Se observaron las puntuaciones más altas de consumo FLV en zonas con niveles de ingresos más altos. Conclusión: La mayor concentración de tiendas de alimentos e bebidas e mayor puntuación de consumo, independientemente da calidad de los productos ofrecidos, fue observado en las áreas geográficas con mayor poder adquisitivo (AU)


Assuntos
Humanos , Verduras/provisão & distribução , Frutas/provisão & distribução , Fabaceae/provisão & distribução , Comércio/estatística & dados numéricos , Abastecimento de Alimentos/estatística & dados numéricos , Saúde da População Urbana , Brasil , Comportamento Alimentar , Ingestão de Alimentos , Consumo de Alimentos , Classe Social , Renda , Países em Desenvolvimento , Inquéritos Epidemiológicos
11.
Allergol. immunopatol ; 42(1): 29-34, ene.-feb. 2014. ilus, tab, graf
Artigo em Inglês | IBECS | ID: ibc-119050

RESUMO

Background: The aim of this study was to assess the sensitivity profile of the population of Fez and Casablanca in Morocco to dry broad bean (Vicia faba), and to investigate the effect of food processing (heat and/or enzymatic hydrolysis by pepsin) on the human IgE binding capacity to broad bean proteins (BBP). Methods: Sera samples from 146 patients with atopic hypersensitivity were recruited in order to evaluate specific IgE levels to native and processed broad bean proteins by ELISA. Under the same conditions, we assessed the immunoreactivity of rabbit IgG obtained by immunisation with native BBP. Results: High IgE levels to BBP were found; in fact, 79.3% of children and 80.4% of adults had positive values. The heat treatment (70 °C during 60 min) of dry beans proteins showed slight reduction in recognition of these antigens by rabbit IgG (22%) and by human IgE (12%). Pepsin hydrolysis decreased rabbit-IgG recognition by 55% in the first 30 min of treatment. In contrast, and under the same conditions, pepsin increased human-IgE recognition with an average of 143% for all patients. However, the combination of the two treatments (heating and pepsin digestion) showed a decrease of 16% in BBP recognition for all patients. Conclusions: This study demonstrates a high sensitivity of a Moroccan population to broad bean proteins which was resistant to heat and digestion by pepsin (AU)


No disponible


Assuntos
Humanos , Hipersensibilidade Imediata/imunologia , Hipersensibilidade Alimentar/imunologia , Fabaceae/efeitos adversos , Marrocos , Proteína Hidrolisada Vegetal
12.
Int. microbiol ; 16(3): 157-163, sept. 2013. ilus, mapas
Artigo em Inglês | IBECS | ID: ibc-118206

RESUMO

Fifty four bacterial strains were isolated from root nodules of the grain legumes Cicer arietinum, Lens esculentus, Phaseolus vulgaris, Pisum sativum, and Vicia faba grown in cultivated lands of Beni-Suef Governorate (Egypt). Repetitive extragenic palindromic (REP)-polymerase chain reaction (PCR) clustered the strains into 15 REP-PCR groups. The nearly complete sequence of the 16S rRNA gene from a representative strain of each REP-PCR pattern showed that the strains were closely related to members of the family Rhizobiaceae of the Alphaproteobacteria. Pairwise alignments between globally aligned sequences indicated that the strains from V. faba had 99.6% identity with Rhizobium leguminosarum, and those from P. vulgaris 99.76% and 100% with sequences from R. leguminosarum and R. mesosinicum, respectively. Strains from P. sativum had 99.76%, 99.84%, and 99.92% sequence identity with R. leguminosarum, R. etli, and R. pisi, respectively, and those from L. esculentus had 99.61% identity with sequences from R. leguminosarum. Sequences of the strains from C. arietinum had 100% identity with those of Mesorhizobium amorphae and M. robiniae, respectively. Nitrogenase activity, determined as acetylene-dependent ethylene production, was detected in nodules formed after inoculation of the corresponding host plant with the representative rhizobial species (AU)


No disponible


Assuntos
Rhizobium/isolamento & purificação , Fabaceae/microbiologia , Grão Comestível/microbiologia , Nodulação , Egito , Filogenia , Nitrogenase/fisiologia , DNA Bacteriano/análise
13.
Nutr. hosp ; 27(4): 1261-1266, jul.-ago. 2012. ilus
Artigo em Inglês | IBECS | ID: ibc-106277

RESUMO

Developing countries are experiencing an epidemic of chronic non-communicable chronic diseases with high socio-economic costs. Studies of traditional foods with beneficial health properties could contribute to diminish these problems. Legumes rich in proteins like Lupinus mutabilis decreases blood glucose and improves insulin sensitivity in animals and humans. We report the results of a phase II clinical trial conducted to assess the role of cooked L. mutabilis and its purified alkaloids on blood glucose and insulin in volunteers with diabetes. Results indicate that consumption of cooked L. mutabilis or its purified alkaloids decreased blood glucose and insulin levels. The decreases in serum glucose concentrations from base line to 90 minutes were statistically significant within both treatment groups; however, there were not differences between groups. Serum insulin levels were also decreased in both groups however the differences were not statistically significant. None of the volunteers in either group presented side effects (AU)


Los países en vías de desarrollo están sufriendo una epidemia de enfermedades crónicas no transmisibles con costos socio-económicos grandes. El estudio de alimentos tradicionales con efectos benéficos para la salud podría contribuir a solucionar estos problemas. El consumo de leguminosas ricas en proteínas como Lupinus mutabilis disminuye las concentraciones de glucosa e insulina en animales y humanos. Aquí se reportan los resultados de un estudio clínico fase II realizado para evaluar la eficacia de L. mutabilis cocido y de un extracto de alcaloides de L. mutabilis en las concentraciones de glucosa e insulina sanguíneas en voluntarios con diabetes. Los resultados indican que el consumo de L. mutabilis cocido o de sus alcaloides purificados disminuyeron las concentraciones de glucosa e insulina en sangre. La disminución en las concentraciones de glucosa sanguínea entre la línea basal y los 90 minutos después del tratamiento fueron estadísticamente significativas dentro de cada grupo de tratamiento, sin embargo no hubieron diferencias entre los grupos. Los niveles de insulina también disminuyeron en ambos grupos pero las diferencias no fueron estadísticamente significativas. Ninguno de los voluntarios presentó efectos adversos a los tratamientos (AU)


Assuntos
Humanos , Diabetes Mellitus Tipo 2/dietoterapia , Lupinus , Hipoglicemiantes/farmacocinética , Alcaloides/farmacocinética , Fabaceae
14.
J. physiol. biochem ; 68(1): 37-45, mar. 2012.
Artigo em Inglês | IBECS | ID: ibc-122376

RESUMO

No disponible


Legumes are considered to have beneficial health implications, which have been attributed to their phytochemical content. Polyphenols are considered the most important phytochemical compounds extensively studied for their antioxidant properties. The aim of the present study was to examine the effects of potent antioxidant legume plant extracts on xanthine oxidase (XO), catalase (CAT) and superoxide dismutase (SOD) activities. XO exerts a dual role, as it is the major contributor of free radicals during exercise while it generates uric acid, the most potent antioxidant molecule in plasma. CAT and SOD are two of the main enzymes of the antioxidant defence of tissues. We demonstrate that the majority of the extracts inhibited XO activity, but they had no effect on CAT inhibition and SOD induction when used at low concentrations. These results imply that the tested extracts may be considered as possible source of novel XO inhibitors. However, we have shown that allopurinol administration, a known XO inhibitor, before exercise reduces performance and induces oxidative stress in rats. Considering the fact that the extracts examined had an inhibitory effect on XO activity, possibly posing a restriction in their characterization as antioxidants, phytochemical antioxidant administration before exercise should probably be reconsidered (AU)


Assuntos
Humanos , Extratos Vegetais/farmacocinética , Xantina Oxidase/farmacocinética , Polifenóis/farmacocinética , Catalase/farmacocinética , Superóxido Dismutase/farmacocinética , Substâncias Protetoras/farmacocinética , Elementos de Resposta Antioxidante , Fabaceae , Exercício Físico/fisiologia
18.
Rev. fitoter ; 8(2): 125-133, jul.-dic. 2008. tab, ilus
Artigo em Espanhol | IBECS | ID: ibc-132779

RESUMO

Exxenterol es un extracto vegetal altamente concentrado en proantocianidinas poliméricas de alto peso molecular, cuya capacidad hipocolesterolemiante ha sido demostrada en estudios preclínicos y clínicos. En los estudios preclínicos realizados con ratas Exxenterol® mostró una eficacia en la reducción del colesterol significativamente superior a la de otras fibras. Los estudios clínicos realizados revelan que el tratamiento con Exxenterol® en sujetos con hipercolesterolemia produce una reducción del colesterol total superior al 20% en 4 semanas, y mayor del 12% en el caso de los triglicéridos. Exxenterol fue eficaz tanto en sujetos tratados con hipolipemiantes como en los no tratados, y no se reportaron efectos adversos relacionados con el tratamiento (AU)


Exxenterol is an herbal extract highly concentrated in high molecular weight proanthocyanidins, which has demonstrated its hypocholesterolemic activity in both, preclinical and clinical studies. In preclinical studies, total cholesterol was reduced significantly compared to other fibers. Clinical studies showed that hypercholesterolemic subjects treated with ExxenterolTM during 4 weeks reduced their total cholesterol serum levels more than 20%, and their triglycerides more than 12%. ExxenterolTM resulted effective in both, subjects treated with other hypolipidemic treatments and subjects without any treatment (AU)


Assuntos
Humanos , Animais , Masculino , Feminino , Ratos , Fabaceae , Robinia , Hipolipemiantes/uso terapêutico , Extratos Vegetais/uso terapêutico , Proantocianidinas/uso terapêutico , Modelos Animais , Polifenóis/uso terapêutico , Anticolesterolemiantes/uso terapêutico , Triglicerídeos/uso terapêutico , Doenças Cardiovasculares/prevenção & controle , Doenças Cardiovasculares/terapia , Hipertensão/terapia , Fatores de Risco
19.
Nutr. hosp ; 23(4): 305-312, jul.-ago. 2008. ilus, tab
Artigo em Inglês | IBECS | ID: ibc-68175

RESUMO

Esta revisión aborda los diferentes usos y propiedades beneficiosas para la salud de la soja, así como, las distintas características químicas y botánicas de esta legumbre. Existen trabajos científicos que aseguran su efecto protector en diferentes enfermedades, sin embargo, otros lo ponen en duda. De todos modos la soja es una excelente fuente de proteína de alto valor biológico, presenta baja cantidad de grasa saturada, contiene gran cantidad de fibra alimentaria y es única entre las legumbres por su contenido en isoflavonas. Existe mucha información acerca del papel beneficioso de la ingesta de legumbres: garbanzos, judías, lentejas y soja, entre otras. La caracterización y los efectos beneficiosos en salud de la soja han sido recientemente estudiados, ya que el descubrimiento de sus componentes funcionales y la controversia que ello suscita ha aumentado el interés en esta legumbre. La mayor parte de estos estudios se centran en la proteína de soja como posible fuente de prevención de las enfermedades cardiovasculares. Este efecto positivo puede ser debido a una disminución del colesterol sanguíneo. Además existen muchos estudios acerca de las isoflavonas, sustancias no nutritivas, asociadas a la prevención y tratamiento de diferentes enfermedades crónicas. También algunos estudios han mostrado el papel beneficioso de la fibra alimentaria de soja. De manera que se podrían considerar las interesantes ventajas nutricionales que proporcionaría la disminución de algunos alimentos de origen animal y la ingesta, en su caso, de alimentos derivados de la soja


Health properties and uses of soybean, as well as the different chemical and botanical characteristics of this legume are shown in this review. Soybean represents an excellent source of high quality protein, it has a low content in saturated fat, it contains a great amount of dietary fibre and its is flavone content makes it singular among other legumes. Many researches have been carried out into the benefit soft legumes: chickpeas, beans, lentils and soy, among others, but characterization and positive health effects of soybeans have been recently studied. The interest in this legume has increased because of its functional components. Most of the studies have been focused on soybean protein as a possible source of prevention against cardiovascular disease. This positive effect may be due to a decrease in serum cholesterol concentrations. In addition, there are many studies on is flavones, non-nutritive substances, associated with prevention and treatment of different chronic diseases. Moreover, some studies have shown the health properties of soy dietary fibre. Therefore, it would be interesting to consider the replacement of animal based foods for soybean foods in order to obtain some nutritional benefits


Assuntos
Humanos , Soja/metabolismo , Soja/química , Proteínas de Soja/farmacocinética , Hipercolesterolemia/dietoterapia , Diabetes Mellitus/dietoterapia , Osteoporose/dietoterapia , Fabaceae/metabolismo , Menopausa
20.
Int. microbiol ; 10(3): 169-176, sept. 2007. tab, ilus
Artigo em Inglês | IBECS | ID: ibc-056708

RESUMO

Transposon Tn5-Mob mutagenesis allowed the selection of a Sinorhizobium fredii HH103 mutant derivative (SVQ 292) that requires the presence of uracil to grow in minimal media. The mutated gene, pyrF, codes for an orotidine-5 - monophosphate decarboxylase (EC 4.1.1.23). Mutant SVQ 292 and its parental prototrophic mutant HH103 showed similar Nod-factor and lipopolysaccharide profiles. The symbiotic properties of mutant SVQ 292 were severely impaired with all legumes tested. Mutant SVQ 292 formed small ineffective nodules on Cajanus cajan and abnormal nodules (pseudonodules) unable to fix nitrogen on Glycine max (soybean), Macroptitlium atropurpureum, Indigofera tinctoria, and Desmodium canadense. It also did not induce any macroscopic response in Macrotyloma axillare roots. The symbiotic capacity of SVQ 292 with soybean was not enhanced by the addition of uracil to the plant nutritive solution (AU)


No disponible


Assuntos
Sinorhizobium fredii/genética , Fabaceae/genética , Mutação , Simbiose/genética , Oligossacarídeos/genética , Mutação/genética
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