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1.
Allergol. immunopatol ; 37(6): 309-313, nov.-dic. 2009. tab
Artigo em Inglês | IBECS | ID: ibc-77017

RESUMO

Some myths and unsupported beliefs about asthma are very popular and enjoy general public acceptance and fairly strong support on the Internet. Onions for cough; dairy products avoidance for asthma; and some other popular myths are reviewed, along with some other medical and mixed (popular and medical) myths comparing their popular and scientific support. Classifying medical statements as realities or unsupported beliefs is a hard and serious work nowadays addressed by Evidence Based Medicine methods, which are not devoid of the influence of medical fashion: the medical community is more prone to accept fashionable statements compared to non-fashionable or old-fashioned statements(AU)


Assuntos
Humanos , Masculino , Feminino , Asma , Cebolas , Religião , Sons Respiratórios , Tosse , Tosse/terapia , Pré-Escolar , Hipersensibilidade , Hipersensibilidade a Leite
2.
Allergol. immunopatol ; 30(5): 295-299, sept. 2002.
Artigo em Espanhol | IBECS | ID: ibc-17166

RESUMO

La familia de las liliáceas ha sido implicada en el desarrollo de rinoconjuntivitis y asma bronquial ocupacional. Presentamos un paciente con síntomas cuando manipulaba especias, incluyendo ajo y cebolla en polvo. Material y métodos: Se realizan test cutáneos con inhalantes, especias comerciales, liliáceas en fresco y con extractos de polvo de especias. Se determinó IgE especifica (CAP-Pharmacía) y se realizó Immunoblotting con ajo.Se llevo a cabo control de pico flujo (PEF) en la zona de manipulación de especias y en la zona de transporte del producto envasado. Se realizó test de provocación nasal con el ajo y la cebolla y se midió la obstrucción nasal mediante rinomanometría anterior activa (RAA). Resultados: Los test cutáneos fueron positivos con el polvo de ajo, cebolla, y con las liliáceas en fresco. La IgE específica fue positiva para ajo y cebolla. El immunoblotting mostró dos bandas de fuerte intensidad correspondiente a 14 y 40 KD con el extracto de ajo. Se objetivó un aumento de la resistencia nasal superior al 100 per cent con ambos extractos (AU)


The Liliacea family has been implicated as a cause of occupational rhinoconjunctivities and bronchial asthma. We report a patient who presented symptoms when he manipulated spices including garlic and onion dusts. Nasal challenge test with active anterior rhinomanometry was used for the diagnosis. Material and methods: Skin-prick tests with common inhalants, commercial spices, fresh Liliaceae and powdered spices diluted in saline solution (10 mg/ml) were performed. Immunoblot and specific IgE (CAP-Pharmacia) were determined. Control peak expiratory flow was monitored during a period at work in an area where spices were manipulated and in an area where they were transported. Nasal challenge test with garlic and onion powder was performed. The resulting nasal obstruction was measured as nasal airway resistance and was determined by rhinomanometry. Results: Skin-prick tests were positive for onion, garlic powder and fresh Liliacea. Specific IgE were positive for garlic and onion. IgE immunoblotting showed very strong bands at 14 and 40 kD with garlic extract. Nasal challenge showed an increase in inspiratory nasal resistance which was higher than 100 % of the basal value for both onion extract and garlic (AU)


Assuntos
Adulto , Masculino , Humanos , Rinomanometria , Western Blotting , Especiarias , Cebolas , Liliaceae , Pós , Rinite Alérgica Perene , Conjuntivite Alérgica , Poluentes Ocupacionais do Ar , Resistência das Vias Respiratórias , Imunoglobulina E , Alho , Testes Cutâneos , Testes de Provocação Nasal , Doenças Profissionais , Testes de Função Respiratória
3.
Allergol. immunopatol ; 28(5): 287-289, sept. 2000.
Artigo em Inglês | IBECS | ID: ibc-8582

RESUMO

A case of severe systemic reactions (intense itching, urticaria, confusion, blurred vision, transient loss of consciousness, sweating, tachycardia) after ingestion of raw or lightly-cooked onion is described. The patient, a 44-year-old woman, had no troubles with well-cooked onions. Differently from the cases of sensitivity to onion described in literature, this patient was monosensitized, being skin tests negative to pollens, inhalants and other foods. The patient had 3.7 kU/L of onion-specific segum IgE, as determined by REAST. The density of onion-specific IgE (calculated as percent ratio to total IgE) was 30.8%. The reactivity of patient's serum IgE towards thermolabile and thermostable components has been tested with unheated and heated (30' at 100 °C) onion extracts bound to polystyrene beads and tested in the RAST system. Unheated extract resulted positive in class 2, heated extract negative, demonstrating that this patients, differently from similar clinical cases described in literature, had IgE antibodies recognizing just thermolabile onion fraction. This is the first case described in literature of a monosensitization to the thermolabile component of onion, negative also to related foods (Liliacee) and characterized by severe systemic reactions. The importance of specific-IgE density (%) rather their absolute amount (kU/L) as parameter predictive for the clinical severity of allergic reactions is discussed (AU)


Historial: se describe un caso de graves reacciones sistémicas (picazón intensa, urticaria, confusión, vista borrosa, pérdida transitoria de la conciencia, transpira ción, taquicardia) como consecuencia de la ingestión de cebollas poco cocidas o crudas. El paciente, de sexo femenino y de 44 años de edad, no había experimentado trastorno al ingerir cebollas bien cocidas. Respecto a los casos de sensibilidad hacia la cebolla descritos en la literatura, esta paciente ha sido monosensibilizada, resultando negativa la prueba cutánea a los pólenes y otros inhalantes y alimentos.Métodos y resultados: en el suero de la paciente se detectó IgE específico frente a cebolla, mediante REAST, con un valor de 3,7 kU/L.La densidad de la IgE específica de la cebolla (calculado como razón porcentual del total de la IgE) ha sido 30,8 por ciento. La reactividad del suero de IgE del paciente hacia los componentes termolábiles y termoestables ha sido comprobada con extractos de cebolla calentados y no calentados (por 30 min a 100 °C) en perlas de poliestirol y probados con el sistema RAST.El extracto no calentado ha resultado positivo de clase 2 mientras que el extracto calentado dio negativo, lo que demuestra que estos pacientes, al contrario de casos clínicos similares descritos en la literatura, presentaban anticuerpos de la IgE que reconocían solamente la fracción termolábil de la cebolla.Conclusiones: este es el primer caso descrito en la literatura de monosensibilización al componente termolábil de la cebolla, negativo también en alimentos que pertenecen a la familia de las Liliáceas y caracterizado por graves reacciones sistémicas. La importancia de la densidad de la IgE específica ( por ciento) respecto a la cantidad absoluta (kU/L), como parámetro que prevé la gravedad clínica de las reacciones alérgicas, resulta controvertida. (AU)


Assuntos
Adulto , Feminino , Humanos , Cebolas , Anafilaxia , Imunoglobulina E , Testes Cutâneos
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