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1.
Pediatr. aten. prim ; 21(83): 265-269, jul.-sept. 2019. tab
Artigo em Espanhol | IBECS | ID: ibc-188643

RESUMO

Las infecciones por adenovirus humano se producen especialmente en niños menores de cinco años, se propagan fácilmente y, en algunos casos, son muy contagiosas. La mayoría de las infecciones son autolimitadas, de tipo respiratorio y gastrointestinal, y muchas veces son difíciles de diferenciar de las ocasionadas por otros virus. Excepcionalmente se confunden clínicamente con otros procesos, tal como ocurrió en los dos casos que presentamos. Sería deseable optimizar los métodos diagnósticos para abordar con más precisión estas infecciones y que nos permitan alejarnos de la incertidumbre


Human adenovirus infections occur especially in children under five years old, spread easily and, in some cases, are highly contagious. The majority of infections are self-limited, affecting the respiratory and gastrointestinal systems, and often are difficult to differentiate from those caused by other viruses. Occasionally they are confused in their clinical expression with other processes, as has happened in the two cases we present. It would be desirable to optimize the diagnostic methods in order to address these infections more accurately and to allow us to move away from uncertainty


Assuntos
Humanos , Feminino , Lactente , Infecções por Adenovirus Humanos/diagnóstico , Adenovírus Humanos/patogenicidade , Diagnóstico Diferencial , Conjuntivite/etiologia , Edema/etiologia
2.
Enferm. infecc. microbiol. clín. (Ed. impr.) ; 37(7): 458-466, ago.-sept. 2019. tab
Artigo em Espanhol | IBECS | ID: ibc-189363

RESUMO

La infección gonocócica es un problema de salud pública a nivel mundial, siendo la segunda infección de transmisión sexual bacteriana más prevalente. El agente etiológico es Neisseria gonorrhoeae, un diplococo gramnegativo, y causa principalmente uretritis en hombres. En mujeres, hasta un 50% de las infecciones pueden ser asintomáticas. N. gonorrhoeae tiene una gran capacidad de desarrollar resistencia antibiótica, con lo que actualmente la última opción terapéutica son las cefalosporinas de espectro extendido. Muchas guías recomiendan la terapia dual con ceftriaxona y azitromicina, pero en los últimos años la resistencia a esta última también está aumentando, con lo que el tratamiento dual se está poniendo en duda por parte de las sociedades científicas


Gonococcal infection is a current public health problem worldwide, being the second most prevalent bacterial sexually transmitted infection. The etiologic agent is Neisseria gonorrhoeae, a gram-negative diplococcus, and mainly causes urethritis in men. In women up to 50% of infections can be asymptomatic. N. gonorrhoeae has a great ability to develop antibiotic resistance, so the last remaining therapeutic option are extended spectrum cephalosporins. Many guides recommend dual therapy with ceftriaxone and azithromycin, but in recent years the resistance to azithromycin is also increasing, so that dual treatment is being questioned by scientific societies


Assuntos
Humanos , Masculino , Feminino , Adolescente , Adulto Jovem , Adulto , Gonorreia/epidemiologia , Doenças Bacterianas Sexualmente Transmissíveis/epidemiologia , Neisseria gonorrhoeae/isolamento & purificação , Gonorreia/tratamento farmacológico , Gonorreia/etiologia , Uretrite/etiologia , Cervicite Uterina/etiologia , Cervicite Uterina/microbiologia , Uretrite/microbiologia , Conjuntivite/etiologia , Técnicas Microbiológicas
3.
Arch. Soc. Esp. Oftalmol ; 94(8): 396-399, ago. 2019. ilus
Artigo em Espanhol | IBECS | ID: ibc-185626

RESUMO

El dupilumab es un fármaco de reciente aprobación por la Food and Drug Administration (FDA) y la European Medical Agency (EMA) para el tratamiento de la dermatitis atópica moderada-severa en adultos. El incremento de la frecuencia de conjuntivitis asociadas a dupilumab ha sido expuesto en publicaciones y ensayos recientes. Presentamos 2 casos de conjuntivitis corticodependiente tratados satisfactoriamente con ciclosporina al 0,1% (Ikervis(R)). No hay casos previos descritos de conjuntivitis asociada a dupilumab tratados con ciclosporina al 0,1% (Ikervis(R))


Dupilumab is a drug that has recently been approved by the Food and Drug Administration (FDA) and European Medical Agency (EMA) for the treatment of moderate-to-severe atopic dermatitis in adults. An increase in frequency of conjunctivitis related to dupilumab treatment has been reported in recent publications and clinical trials. We report two steroid-dependent cases satisfactorily treated with cyclosporine 0.1% (Ikervis(R)). To our knowledge there are no reported cases of dupilumab-associated conjunctivitis treated with cyclosporine 0.1% (Ikervis(R)


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Anticorpos Monoclonais Humanizados/efeitos adversos , Conjuntivite/induzido quimicamente , Conjuntivite/tratamento farmacológico , Ciclosporina/uso terapêutico , Dermatite Atópica/tratamento farmacológico , Imunossupressores/uso terapêutico , Corticosteroides/uso terapêutico , Conjuntivite/diagnóstico por imagem , Fluormetolona/uso terapêutico , Glucocorticoides/uso terapêutico , Subunidade alfa de Receptor de Interleucina-4 , Recidiva
4.
Acta pediatr. esp ; 76(11/12): e164-e165, nov.-dic. 2018.
Artigo em Espanhol | IBECS | ID: ibc-177429

RESUMO

La blefaroqueratoconjuntivitis (BQC) es una enfermedad inflamatoria crónica del borde palpebral con posible lesión secundaria de la superficie conjuntival y corneal. Presentamos el caso de una paciente de 6 años a la que, en el control de salud correspondiente a su edad, se le detectó una disminución de la agudeza visual, por lo que fue derivada al servicio de oftalmología, donde fue diagnosticada de BQC. La prevalencia de este síndrome es desconocida en nuestro medio y, por tanto, infradiagnosticada, en parte debido a su amplio espectro de presentación, que aún dificulta más su detección, y porque puede ser asintomática, como en el presente caso


Blepharokeratoconjunctivitis (BKC) is a chronic inflammatory disease of the edge palpebral with possible secundary injury of the conjunctival and corneal surface. We present a 6 year-old patient who, in the routine medical checkup within her age range, is detected a decrease in the visual acuity and therefore taken to the department of ophthalmology, where she is diagnosed a BKC. The prevalence of this syndrome is unknown in our environment, on one hand because is little known and therefore underdiagnosed, and the other hand for its wide presentation range, which makes its detection even more difficult and also because it could become asymptomatic, like in our case


Assuntos
Humanos , Feminino , Criança , Acuidade Visual , Blefarite/diagnóstico , Conjuntivite/diagnóstico , Opacidade da Córnea/diagnóstico , Ceratite/diagnóstico , Blefarite/complicações , Conjuntivite/complicações , Corticosteroides/administração & dosagem , Lubrificantes Oftálmicos/administração & dosagem , Administração Tópica , Túnica Conjuntiva , Túnica Conjuntiva/patologia , Córnea/patologia
5.
Arch. Soc. Esp. Oftalmol ; 93(10): 511-514, oct. 2018. ilus
Artigo em Espanhol | IBECS | ID: ibc-175128

RESUMO

CASO CLÍNICO: Mujer de 81 años en tratamiento con una combinación fija de timolol y brimonidina en colirio que fue diagnosticada en urgencias de uveítis anterior aguda hipertensiva granulomatosa. La paciente respondió favorablemente a la retirada del colirio sin mostrar recaída posterior. DISCUSIÓN: La uveítis por brimonidina es un efecto adverso raro, pero que debe ser conocido. Una vez se llega al diagnóstico de sospecha, el tratamiento efectivo es la retirada del colirio de brimonidina, con adición o no de corticoides tópicos para controlar la inflamación según la gravedad del cuadro. Se trata de un proceso con un pronóstico excelente


CLINICAL CASE: The case concerns an 81-year-old woman on treatment with a topical fixed combination of timolol and brimonidine who was diagnosed in the Emergency Department with acute anterior granulomatous hypertensive uveitis. The patient responded favourably to the withdrawal of the eye drops without showing any subsequent relapse. DISCUSSION: Uveitis due to brimonidine is a rare adverse effect, but it must be known. Once the diagnosis is suspected, the effective treatment is the withdrawal of brimonidine, with or without the addition of topical corticosteroids to control inflammation depending on the severity of the condition. It is a process with an excellent prognosis


Assuntos
Humanos , Feminino , Idoso de 80 Anos ou mais , Uveíte Anterior/induzido quimicamente , Uveíte Anterior/diagnóstico por imagem , Combinação Tartarato de Brimonidina e Maleato de Timolol/efeitos adversos , Hiperemia/etiologia , Pressão Intraocular , Acuidade Visual , Lâmpada de Fenda , Blefarite/complicações , Conjuntivite/complicações
6.
Rev. clín. med. fam ; 11(3): 166-168, oct. 2018. ilus
Artigo em Espanhol | IBECS | ID: ibc-176095

RESUMO

La miasis ocular es la invasión del órgano ocular y anejos por larvas de insectos que produce dolor, ardor, picazón y enrojecimiento uniocular de inicio abrupto acompañado de sensación de cuerpo extraño en movimiento. Las larvas se acantonan y reproducen invadiendo el tejido progresivamente. Mediante un caso clínico, presentamos los procedimientos diagnósticos y terapéuticos a realizar. Se trata de un agricultor de 56 años que acude a urgencias por prurito y sensación de ocupación en el ojo derecho de 24 horas de evolución sin irritación conjuntival, ni alteraciones visuales, ni limitación motora y el test de fluoresceína fue negativo. Tras lavarlo se evidencian helmintos en el espacio palpebral que más tarde serán identificados como larvas de mosca. Con antibiótico local profiláctico, analgésico tópico y revisiones periódicas en Oftalmología para su arrastre manual se consiguió la recuperación completa. No precisó de tratamiento antiparasitario pues no se objetivó lesión o problema ocular. La miasis es una patología infrecuente que suele confundirse con una conjuntivitis alérgica o viral. Las medidas higiénicas son imprescindibles para prevenirlas como son la limpieza del entorno, la buena higiene personal, la provisión de saneamiento básico y educación sanitaria en el medio rural


Ocular myiasis is the infestation of the eye and adnexa by insect larvae that produces pain, burning, itching and uniocular redness of abrupt onset accompanied by a moving foreign body sensation. The larvae settle and reproduce invading the tissue progressively. Through a clinical case, we present the diagnostic and therapeutic procedures to be performed. This is the case of a 56-year-old farmer who goes to the emergency room for pruritus and foreign body sensation in the right eye for 24 hours after onset without conjunctival irritation, visual disturbances, or limited movement, and with negative fluorescein test. After washing, helminths are evident in the palpebral space, whichwill later be identified as fly larvae. With local prophylactic antibiotics, topical analgesics and periodic control visits to Ophthalmology for manual removal, complete recovery was achieved. He did not need antiparasitic treatment because no eye injury or problem was observed. Myiasis is an infrequent pathology that is often confused with allergic or viral conjunctivitis. Hygiene measures are essential to prevent them, such as cleaning the environment, a good personal hygiene, the provision of basic sanitation and health education in rural areas


Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Miíase/diagnóstico por imagem , Oftalmopatias/parasitologia , Conjuntivite/parasitologia , Dípteros/patogenicidade , Helmintíase/complicações , Helmintos/isolamento & purificação , Prurido/etiologia , Zoonoses/transmissão , Zona Rural , Antiparasitários/uso terapêutico
7.
Pediatr. catalan ; 78(3): 107-110, jul.-sept. 2018. tab, graf
Artigo em Catalão | IBECS | ID: ibc-174674

RESUMO

Fonament: La cel·lulitis orbitària (CO) és un diagnòstic de sospita clínica que requereix confirmació radiològica. És habitual l'ingrés amb tractament antibiòtic a l'espera de la confirmació diagnòstica. Objecti: Avaluar el possible impacte de la realització d'una tomografia computada (TC) en el maneig a Urgències del pacient amb sospita de CO. Mètode: Estudi retrospectiu, descriptiu-observacional. Es van revisar les històries clíniques dels pacients atesos a Urgències entre 2011 i 2014 amb diagnòstic de cel·lulitis periorbitària/orbitària. Es van incloure els casos amb sospita de CO. Es van excloure els pacients sense TC. Es defineix CO com la cel·lulitis que afecta més enllà del septe orbitari. Es van considerar criteris d'ingrés: edat <1 any, immunosupressió, vacunació incompleta, triangle d'avaluació pediàtrica (TAP) alterat, mala resposta antibiòtica i presència d'algun dels símptomes o signes oculars següents: dolor amb els moviments oculars, oftalmoplegia, disminució de l'agudesa visual, alteració dels reflexos pupil•lars, edema conjuntival i proptosi. Resultats: Es van incloure 85 pacients. Tots van ser immuno-competents, ben vacunats i presentaven un TAP normal. Vint (23,5%) presentaven un o més signes o símptomes oculars. Vint-i-set (31,8%) tenien un o més criteris d'ingrés. Dels 58 sense criteris d'ingrés, en 38 (65,5%) no es va confirmar CO. A 18 (31%) d'aquests pacients se'ls va fer TC a Urgències; en 13 casos es va indicar maneig ambulatori, ja que l'afectació era només preseptal. Es va confirmar CO en 34 pacients (concordança diagnòstica 40%).Conclusions: En més de la meitat dels pacients amb sospita de CO, aquesta no es confirma radiològicament. Fer una TC a Urgències, en els pacients que no tenen criteris d'ingrés, evitaria hospitalitzacions innecessàries en un nombre significatiu


Fundamento: La celulitis orbitaria (CO) es un diagnóstico de sospecha clínica que requiere confirmación radiológica. Es habitual el ingreso con tratamiento antibiótico a la espera de la confirmación diagnóstica. Objetivo: Evaluar el posible impacto de la realización de una tomografía computadorizada (TC) en el manejo en urgencias del paciente con sospecha de CO. Método: Estudio retrospectivo, descriptivo-observacional. Se revisaron las historias clínicas de los pacientes atendidos en Urgencias entre 2011 y 2014 con el diagnóstico de celulitis periorbitaria/orbitaria. Se incluyeron aquellos con sospecha de CO. Se excluyeron los pacientes sin TC. Se define CO como la celulitis que afecta más allá del septo orbitario. Se consideraron criterios de ingreso: edad <1 año, inmunosupresión, vacunación incompleta, triángulo de evaluación pediátrica (TEP) alterado, mala respuesta antibiótica y presencia de alguno de los siguientes síntomas o signos oculares: dolor con los movimientos oculares, oftalmoplejía, disminución de la agudeza visual, alteración de los reflejos pupilares, edema conjuntival y proptosis. Resultados: Se incluyeron 85 pacientes. Todos fueron inmunocompetentes, bien vacunados y presentaron un TEP normal. Veinte (23,5%) presentaron uno o más signos o síntomas oculares. Veintisiete (31,8%) tenían uno o más de los criterios de ingreso. De los 58 sin criterios de ingreso, en 38 (65,5%) no se confirma CO. A 18 (31%) de estos pacientes se realizó TC en urgencias; en 13 casos se indicó manejo ambulatorio, dado que la afectación era sólo preseptal. Se confirmó CO en 34 pacientes (concordancia diagnóstica 40%) Conclusiones: En más de la mitad de los pacientes con sospecha de CO, ésta no se confirma radiológicamente. La realización de TC en urgencias, en los pacientes que no tienen criterios de ingreso, evitaría hospitalizaciones innecesarias en un número significativo


Background: Orbital cellulitis (OC) is a diagnos hospitalization with intravenous antibiotic therapy until the diagnosis is confirmed. Objective: To evaluate the impact of performing a computerized tomography (CT) in the emergency department when orbital ellulitis is suspected on the initial management of the patient. Method: Descriptive observational retrospective study. Clinical records of patients who were attended in the emergency department with the diagnosis of periorbital/orbital cellulitis between 2011 and 2014 were reviewed. Patients with suspected OC were included, and those without T were excluded. OC was defined as postseptal when there was inflammatory extension posterior to the orbital septum. Criteria for hospitalization were: age < 1 year-old, immunosuppression, incomplete vaccinations, altered pediatric assessment triangle PAT), inadequate antibiotic response, and the presence of any of the following: painful ocular movements, ophthalmoplegia, decline of visual acuity, altered pupillary response, conjunctival edema, and proptosis. Results: Eighty-five patients were included. All of hem were immunocompetent, correctly vaccinated, and had normal PAT. Twenty patients (23.5%) presented > 1 ocular signs-symptoms, and 27 (31.8%) had > 1 riteria for hospitalization. In 38 of the 58 pa-tients (65.5%) without hospitalization criteria, C as not confirmed. In 18 (31%) of them, CT was performed in the Emergency Department; in 3 of them the affected area was only preseptal, and ambulatory management was indicated. he diagnosis of OC was confirmed in 34 cases (diagnostic concordance: 40%).Conclusions: in more than half of the patients with clinical suspicion of OC there is not radiological confirmation. Performing a CT in the Emergency Department in patients without hospitalization criteria would avoid unnecessary hospitalizations in a significant proportion of patients.is of clinical suspicion that requires radiologic confirmation. Performing a CT in the Emergency Department in patients without hospitalization criteria would avoid unnecessary hospitalizations in a significant proportion of patients


Assuntos
Humanos , Masculino , Feminino , Lactente , Tomografia Computadorizada por Raios X/métodos , Celulite Orbitária/diagnóstico por imagem , Blefaroptose/epidemiologia , Oftalmoplegia/epidemiologia , Conjuntivite/epidemiologia , Estudos Retrospectivos , Serviço Hospitalar de Emergência/estatística & dados numéricos , Tratamento de Emergência/métodos , Diagnóstico Diferencial
8.
Reumatol. clín. (Barc.) ; 14(4): 233-235, jul.-ago. 2018. ilus, tab
Artigo em Espanhol | IBECS | ID: ibc-175929

RESUMO

El síndrome de Sjögren (SS) es una enfermedad sistémica autoinmune que afecta principalmente a las glándulas exocrinas. Se ha reportado que la asociación entre SS y compromiso respiratorio ocurre entre el 11 y el 45% de los casos. El diagnóstico se basa en la integración de criterios clínicos, inmunológicos e histopatológicos. Se presenta el caso de un masculino de 58 años, con SS, disnea grave y exacerbaciones recurrentes de la vía respiratoria, asociado a bronquiolitis-bronquiectasias. La ausencia de anticuerpos anti-Ro y anti-La, relacionados con la gravedad de la bronquiolitis, es una forma de presentación poco caracterizada en este grupo de pacientes, más aún, su tratamiento óptimo no está establecido


Sjögren's syndrome (SS) is a systemic autoimmune disease that mainly affects the exocrine glands. It has been reported that the association between SS and respiratory involvement occurs in 11% and 45% of cases, and can be the initial manifestation of the disease. The diagnosis is based on the integration of clinical, immunological and histopathological criteria. This paper examines a 58-year-old man with SS, severe dyspnea and recurrent exacerbations associated with bronchiolitis-bronchiectasis. The absence of anti-Ro and anti-La antibodies associated with severe bronchiolitis is a clinical presentation that is poorly characterized in this group of patients; moreover, how to treat them remains unclear


Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Síndrome de Sjogren/complicações , Bronquiolite/complicações , Bronquiectasia/complicações , Testes de Função Respiratória , Hiperemia/complicações , Conjuntivite/etiologia , Sialadenite/diagnóstico , Biópsia por Agulha Fina , Glândulas Salivares/patologia
10.
Pediatr. aten. prim ; 19(74): 163-166, abr.-jun. 2017. tab
Artigo em Espanhol | IBECS | ID: ibc-164181

RESUMO

El hipertiroidismo en la infancia es muy infrecuente; en la mayoría de los casos es de origen autoinmune (enfermedad de Graves). La tríada clásica se compone de bocio, oftalmopatía y dermatopatía. Su presentación clínica en la edad pediátrica es muy variable y de comienzo habitualmente insidioso, lo que en muchas ocasiones conlleva una demora en el diagnóstico y tratamiento. Presentamos el caso de una paciente de 12 años que consulta por una conjuntivitis crónica bilateral refractaria a tratamientos tópicos habituales, que finalmente fue derivada al Servicio de Endocrinología Pediátrica ante la sospecha de oftalmopatía de Graves (AU)


Hyperthyroidism in childhood is a very rare condition, and in most cases of autoimmune etiology (Graves’ disease). The classic triad consists of goiter, ophthalmopathy and dermopathy. Clinical presentation in children is highly variable and often with an insidious onset, which on many occasions may cause a delay on its diagnosis and treatment. A case is reported here where a 12-year-old patient, who showed a refractory bilateral chronic conjunctivitis refractary to topical usual treatments, was finally referred to the Pediatric Endocrinology Department due to the likelihood of her suffering from Graves' ophthalmopathy (AU)


Assuntos
Humanos , Feminino , Criança , Conjuntivite/complicações , Conjuntivite/diagnóstico , Recidiva , Doença de Graves/complicações , Hipertireoidismo/complicações , Antagonistas dos Receptores Histamínicos/uso terapêutico , Ceratite/complicações , Oftalmopatia de Graves/complicações , Oftalmopatia de Graves/diagnóstico , Crise Tireóidea/complicações , Ceratite/diagnóstico , Diagnóstico Diferencial
11.
Allergol. immunopatol ; 45(3): 227-233, mayo-jun. 2017. tab
Artigo em Inglês | IBECS | ID: ibc-162383

RESUMO

Background. The objective of the study was to examine the relationship between asthma and overweight-obesity in Spanish children and adolescents and to determine whether this relationship was affected by gender and atopy. Methods. The study involves 8607 Spanish children and adolescents from the International Study of Asthma and Allergies in Childhood phase III. Unconditional logistic regression was used to obtain adjusted odds ratios (OR) and 95% confidence intervals (95% CI) for the association between asthma symptoms and overweight-obesity in the two groups. Afterwards, it was stratified by sex and rhinoconjunctivitis. Results. The prevalence of overweight and obesity in 6-7-year-old children was 18.6% and 5.2% respectively and in 13-14 year-old teenagers was 11.4% and 1.1% respectively. Only the obese children, not the overweight children, of the 6-7 year old group had a higher risk of any asthma symptoms (wheezing ever: OR 1.68 [1.15-2.47], asthma ever: OR 2.29 [1.43-3.68], current asthma 2.56 [1.54-4.28], severe asthma 3.18 [1.50-6.73], exercise-induced asthma 2.71 [1.45-5.05]). The obese girls had an increased risk of suffering any asthma symptoms (wheezing ever: OR 1.73 [1.05-2.91], asthma ever: OR 3.12 [1.67-5.82], current asthma 3.20 [1.65-6.19], severe asthma 4.83[1.94-12.04], exercise-induced asthma 3.68 [1.67-8.08]). The obese children without rhinoconjunctivitis had a higher risk of asthma symptoms. Conclusions. Obesity and asthma symptoms were associated in 6–7 year-old children but not in 13-14 year-old teenagers. The association was stronger in non-atopic children and obese girls (AU)


No disponible


Assuntos
Humanos , Masculino , Feminino , Criança , Adolescente , Obesidade/complicações , Asma/complicações , Asma/epidemiologia , Asma Induzida por Exercício/epidemiologia , Conjuntivite/epidemiologia , Sobrepeso/complicações , Protocolos Clínicos , Inquéritos e Questionários , Espanha/epidemiologia , Conjuntivite/complicações
12.
Arch. Soc. Esp. Oftalmol ; 92(5): 241-244, mayo 2017. ilus
Artigo em Espanhol | IBECS | ID: ibc-162629

RESUMO

INTRODUCCIÓN: El síndrome de Stevens-Johnson y la necrólisis epidérmica tóxica son 2 graves enfermedades inmunológicas dentro del contexto de síndrome mucocutáneo ampolloso, con diferente grado de afectación cutánea y que suelen presentar afectación de al menos 2 membranas mucosas. Casos clínicos: Presentamos 3 casos clínicos, 2 de ellos con importantes secuelas oftalmológicas que habían recibido tratamiento farmacológico como posible desencadenante, y otro cuadro más larvado causado por Mycoplasma pneumoniae. DISCUSIÓN: El oftalmólogo desempeña un papel crucial en la evolución y cuidados oculares del paciente para intentar evitar la aparición de secuelas y la consiguiente pérdida de visión


INTRODUCTION: Stevens-Johnson syndrome and toxic epidermal necrolysis are two serious immune diseases within the context of bullous mucocutaneous syndrome. These have varying degrees of involvement of the skin and usually at least two mucous membranes. Clinical cases: Three clinical cases are presented, two of them with significant ophthalmological sequelae, who had received drug treatment as a possible trigger, and another milder clinical case caused by Mycoplasma pneumoniae. DISCUSSION: The ophthalmologist plays a crucial role in the outcome and eye care of the patient in order to try to avoid the appearance of sequelae and subsequent loss of vision


Assuntos
Humanos , Masculino , Feminino , Pré-Escolar , Criança , Síndrome de Stevens-Johnson/diagnóstico , Dermatite Esfoliativa/diagnóstico , Eritema/diagnóstico , Conjuntivite/etiologia , Pneumonia por Mycoplasma/complicações , Corticosteroides/uso terapêutico , Xeroftalmia/etiologia , Úlcera da Córnea/etiologia
13.
Allergol. immunopatol ; 45(2): 198-207, mar.-abr. 2017. tab
Artigo em Inglês | IBECS | ID: ibc-160526

RESUMO

Background. Glutaraldehyde-modified natural allergen extracts show significant reduction in the IgE-binding capacity and proteolytic activity. This allows the administration of higher doses in a shorter period of time, and to mix different allergen extracts. Objective. Evaluate the safety of different concentrations and mixtures of glutaraldehyde-modified allergen extracts in a large group of paediatric and adult patients undergoing specific immunotherapy treatment. Materials and methods. 1855 patients (1156 adults and 699 children), suffering from rhinoconjunctivitis and/or asthma, participated in an observational multicentre cohort study, to evaluate the safety of immunotherapy using vaccines containing modified allergen extracts. Patients were monosensitised, or polysensitised, and received a therapeutic vaccine containing polymerised allergen extracts adsorbed onto aluminium hydroxide. Safety was assessed by recording all side reactions related to immunotherapy. Results. The clinically relevant local reactions totalled 120, (90 immediate and 30 delayed) (1.02% of injections). Of them, 31 (0.26% of injections) occurred in children (26 immediate and 5 delayed) and 89 (0.76% of injections) in adults (64 immediate and 25 delayed). There were 38 systemic reactions. Eleven reactions were immediate (9 of grade 1 and 2 of grade 2) and 27 delayed (22 of grade 1 and 5 of grade 2). There were seven grade 2 systemic reactions (0.06% of the injections). No differences (P>0.05) in the number of reactions were observed between adults and children and between treatments were found in systemic reactions. All systemic reactions were mild and resolved spontaneously without the need of medication. Conclusion. Specific immunotherapy using natural modified allergen vaccines is safe to treat allergic patients, even at higher doses and in mixtures of unrelated allergen extracts. The percentage of adverse reactions detected is lower than those reported in the literature with native unmodified allergen extracts (AU)


No disponible


Assuntos
Humanos , Masculino , Feminino , Recém-Nascido , Lactente , Pré-Escolar , Criança , Adolescente , Adulto , Alérgenos/imunologia , Imunoterapia/métodos , Glutaral/uso terapêutico , Asma/imunologia , Pólen/imunologia , Rinite Alérgica Sazonal/imunologia , Conjuntivite/imunologia
15.
Arch. Soc. Esp. Oftalmol ; 92(1): 37-39, ene. 2017. ilus
Artigo em Espanhol | IBECS | ID: ibc-159165

RESUMO

CASO CLÍNICO: Una mujer de 33 años consulta por conjuntivitis granulomatosa unilateral, adenopatías regionales homolaterales y fiebre. Se demuestra una infección por Bartonella henselae mediante inmunofluorescencia indirecta y se establece el diagnóstico de síndrome oculoglandular de Parinaud. La evolución después de tratamiento con doxiciclina oral es satisfactoria. Discusión: El síndrome oculoglandular de Parinaud es la manifestación ocular más frecuente de una infección por Bartonella henselae


CLINICAL CASE: 33-year old woman presents with unilateral granulomatous conjunctivitis, ipsilateral regional lymphadenopathy and fever. A Bartonella henselae infection is demonstrated by indirect immunofluorescence, and a diagnosis of a Parinaud’s oculoglandular syndrome is established. Outcome after treatment with oral doxycycline is satisfactory. Discussion: Parinaud’s oculoglandular syndrome is the most frequent ocular manifestation of a Bartonella henselae infection


Assuntos
Humanos , Feminino , Adulto , Transtornos da Motilidade Ocular/diagnóstico , Conjuntivite/etiologia , Doença da Arranhadura de Gato/complicações , Infecções por Bartonella/complicações , Bartonella henselae/patogenicidade , Doxiciclina/uso terapêutico
17.
Arch. Soc. Esp. Oftalmol ; 91(11): 556-558, nov. 2016. ilus
Artigo em Espanhol | IBECS | ID: ibc-157166

RESUMO

CASO CLÍNICO: Varón de 23 años con ptosis unilateral izquierda de 2 años de evolución. Tras meses de tratamiento ineficaz para conjuntivitis vernal, la biopsia demostró una amiloidosis tarsal. La resolución quirúrgica del cuadro fue satisfactoria, tanto anatómica como funcionalmente. Discusión: La amiloidosis ocular es una enfermedad rara que se debe sospechar en casos de masas infiltrativas. El método diagnóstico es la biopsia. El tratamiento debe ser individualizado


CASE REPORT: A 23-year-old man presented with a unilateral left ptosis of two years onset. After ineffective treatment for vernal conjunctivitis for several months, the biopsy demonstrated tarsal amyloidosis. Surgical resolution of the case was anatomically and functionally satisfactory. DISCUSSION: Ocular amyloidosis is a rare disease that must be suspected with infiltrative mass lesions. Biopsy is the diagnostic method. Treatment should be individualised


Assuntos
Humanos , Masculino , Adulto Jovem , Amiloidose/complicações , Oftalmopatias/diagnóstico , Blefaroptose/etiologia , Conjuntivite/etiologia , Diagnóstico Diferencial , Vermelho Congo , Microscopia/métodos
19.
Rev. esp. pediatr. (Ed. impr.) ; 72(1): 58-59, ene.-feb. 2016.
Artigo em Espanhol | IBECS | ID: ibc-153257

RESUMO

Se presenta el caso de un varón prematuro y con cardiopatía congénita de 4 meses de edad que presentaba unas bronquiolitis y conjuntivitis causadas por CI Metapneumovirus humano. El virus se detectó tanto en el aspirado nasofaríngeo como en la secreción conjuntival. Debido a la rareza de esta entidad, se revisa la literatura correspondiente a esta entidad (AU)


A premature male with congenital heart disease and 4 months of age had a bronchiolitis and conjunctivitis caused by human metapneumovirus. The virus was detected in both the nasopharyrngeal aspirate as coniunctival secretion. Because of the rarity of this entity we reviewed scientific literature (AU)


Assuntos
Humanos , Masculino , Lactente , Conjuntivite Viral/complicações , Conjuntivite Viral/diagnóstico , Conjuntivite Viral/etiologia , Conjuntivite/complicações , Conjuntivite/virologia , Metapneumovirus , Metapneumovirus/imunologia , Metapneumovirus/isolamento & purificação , Combinação Amoxicilina e Clavulanato de Potássio/uso terapêutico , Doenças do Prematuro/diagnóstico , Bronquiolite/complicações , Bronquiolite/diagnóstico , Bronquiolite/terapia , Hospitalização/estatística & dados numéricos , Hospitalização/tendências , Tempo de Internação/tendências
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