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J. physiol. biochem ; 66(2): 137-142, jun. 2010. tab
Artigo em Inglês | IBECS | ID: ibc-122837

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Previous studies with different results have suggested that total and bioavailable testosterone levels are modified by physical exercise. Such changes may be related to modifications in cortisol levels and could be reflected in some urine androgens. To determine how weight lifting training may affect serum and urinary androgens, we measured total serum testosterone (T), cortisol, sex hormonebinding globulin (SHBG) and urinary testosterone, epitestosterone, androsterone, and etiocholanolone, in a group of 19 elite weight lifters after 20 weeks of training. SHBG increased (from 27.5 ± 9.5 to 34.7 ± 8.1 nM, p < 0.05) whereas T/SHBG decreased significantly (from 1.10 ± 0.4 to 0.85 ± 0.3, p < 0.05). Serum total testosterone and cortisol did not change significantly. In urine, androsterone and etiocholanolone decreased significantly, whereas testosterone and epitestosterone remained unchanged. Changes in T/SHBG were related positively with changes in urinary androgens (r = 0.680, p < 0.01), and changes in SHBG were negatively related with changes in urinary androgens (r = −0.578, p < 0.01). These results suggest that intense physical activity may have an influence on the elimination of androgenic hormones due mainly to changes in their transporting protein SHBG (AU)


Assuntos
Humanos , Androgênios/urina , Globulina de Ligação a Hormônio Sexual/fisiologia , Atividade Motora/fisiologia , Testosterona/sangue , Epitestosterona/sangue , Androsterona/sangue , Etiocolanolona/sangue , Proteínas de Transporte , Esportes/fisiologia , Levantamento de Peso/fisiologia
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