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1.
Rev. psicol. deport ; 24(supl.1): 21-25, 2015. tab
Artigo em Inglês | IBECS | ID: ibc-147264

RESUMO

It was analyzed in what measurement the characteristics of the task in small side games influence the perception of effort (RPE) and his relation between the time of game and the RPE the type of tasks. Ten minibasketball players performed 50 tasks (10 training sessions, 450 records RPE, 5 with duration of 8, 10 or 12 minutes). Based on the description 7 variables were codified: Aim: (Assault / Defense / Compound), Duration: (8 minutes / more than 8 minutes), Space: (Track completes / 1/2 Track / 1/4 of Track), numerical Equality: (Without rival / numerical Inequality / numerical Equality), Transition: (If / Not), Player of support: (If / Not), Relation between players: (attackers[n] x defenders[n]). No parametric analysis and an analysis of the variable RPE in function of the characteristics of the task with logistic multinomial regression from the RPE were used. RPE's average in all the variables were 6.87 ± 1.76. Four variables contribute the model: Time of the task (X2 = 183.49; df= 8; p < .001), Relation among players (X2 = 63.71; df= 10; p < .001), Transition (X2 = 15.37; df= 2; p < .01) and the Aim (X2 = 9.68; df= 4; p < .05). The % of classification of the model for the group RPE (8-9), 90.1 % and for the group RPE (0-6), 71.6 %. The total percentage of classification predicted was 66.4. The tasks of 8 minutes in the group of RPE (0-6) have more possibilities of having RPE lower than those of any more 10 or 12 minutes. The tasks of attack have more possibilities of having a lower RPE. The characteristics of tasks influence the RPE. More than 8 minutes favor a very high RPE when the presence of attackers and defenders in 1x1 and 2x2 exist (AU)

Assuntos
Humanos , Masculino , Feminino , Basquetebol/classificação , Basquetebol/educação , Teste de Esforço/métodos , Teste de Esforço/enfermagem , Ensaios de Triagem em Larga Escala/classificação , Ensaios de Triagem em Larga Escala/métodos , Basquetebol/fisiologia , Basquetebol/normas , Teste de Esforço/normas , Teste de Esforço , Ensaios de Triagem em Larga Escala/normas , Ensaios de Triagem em Larga Escala
2.
Rev. esp. med. nucl. imagen mol. (Ed. impr.) ; 33(1): 56-57, ene.-feb. 2014.
Artigo em Espanhol | IBECS | ID: ibc-118736
3.
Clin. transl. oncol. (Print) ; 11(10): 651-658, oct. 2009. ilus
Artigo em Inglês | IBECS | ID: ibc-123690

RESUMO

The discovery of novel targets that can be pharmacologically exploited to lead to a better disease outcome has long been an aim of biomedical research. At present, the technology and robotisation available have pushed the search for novel molecules to a high-throughput screening (HTS) context, making it possible to screen several hundreds of compounds or genes in a single day. High-content screenings (HCS) have added a refined complexity to the screening processes, as the information drawn from an image- based assay is more complete than the monoparametric readouts obtained in classical HTS assays. Here, we review the development of HCS platforms to identify molecules influencing FOXO nuclear relocation and activation as pharmacological targets, their applicability and the future directions of the screening field (AU)

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Assuntos
Humanos , Feminino , Antineoplásicos/uso terapêutico , Neoplasias/terapia , Fatores de Transcrição Forkhead/antagonistas & inibidores , Descoberta de Drogas/tendências , Ensaios de Triagem em Larga Escala/métodos , Ensaios de Triagem em Larga Escala/tendências , Ensaios de Triagem em Larga Escala