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1.
Eur. j. anat ; 24(2): 121-128, mar. 2020. ilus, tab
Artigo em Inglês | IBECS | ID: ibc-191239

RESUMO

The olfactory fossa (OF) is a depression in the anterior cranial cavity whose floor is formed by the cribriform plate of ethmoid, bounded laterally by the lateral lamella of cribriform plate and medially by crista galli. Keros categorized the olfactory fossa depth into 3 types. For a successful endoscopic sinus surgery, the surgeons should pay attention to the details when dealing with the complex anatomy of the paranasal sinuses (PNS) and skull base. The aim of this study was to describe the distribution of Keros classification of the height of ethmoid roof among Saudi population by using multidetector computed tomography (MDCT). This was a retrospective study conducted on 511 patients (360 males and 151 female) referred for MDCT assessment of PNS over a two-year period. The mean age of our patients was 34.47± 10.69 years, aged between 18 and 79 years. Patients with nasal trauma, surgeries or any pathological diseases affecting the ethmoid roof were excluded from the study. Keros type II was the commonest presentation observed in 53.2% of cases, followed by type I in 12.5%, then type III in 11.7% of cases. Out of the 511 patients analyzed, 115 (22.5%) cas-es had asymmetry (different types of OF) on both sides. Conclusion: The majority of studied Saudi adult population showed Keros type II (53.3%), followed by type I (12.5%). Keros type III was seen in 11.7% among the studied population


No disponible


Assuntos
Humanos , Masculino , Feminino , Adolescente , Adulto Jovem , Adulto , Pessoa de Meia-Idade , Idoso , Osso Etmoide/anatomia & histologia , Osso Etmoide/diagnóstico por imagem , Seio Etmoidal/anatomia & histologia , Seio Etmoidal/diagnóstico por imagem , Tomografia Computadorizada Multidetectores , Estudos Retrospectivos , Arábia Saudita
2.
An. pediatr. (2003. Ed. impr.) ; 91(3): 189-198, sept. 2019. tab, ilus
Artigo em Espanhol | IBECS | ID: ibc-186730

RESUMO

Introducción: Se ha descrito la regeneración del timo tras la quimioterapia en niños con linfoma y, para evitar diagnosticar incorrectamente estos casos como recurrencias, los facultativos han de familiarizarse con la hiperplasia tímica de rebote (HTR) y tener en consideración su posible ocurrencia. Nuestro objetivo fue estimar la prevalencia de HTR en niños con linfoma tras la quimioterapia y evaluar las características clínicas, evolución y hallazgos de las pruebas de imagen mediante tomografía computarizada (TC) y la gammagrafía con galio 67 (GA-67). Pacientes y métodos: Estudio retrospectivo transversal, mediante la revisión de las historias clínicas de niños diagnosticados de linfoma, realizado en la Clínica Ambulatoria de Oncología Infantil del Centro de Oncología de Yeda, Arabia Saudita. Resultados: Se detectó HTR en el 51,9% de los pacientes con linfoma (14/27 pacientes). La HTR ocurrió una mediana de 2,5 meses tras finalizarse el tratamiento (rango: 2,0-4,25 meses). Los pacientes con HTR recibieron tratamientos significativamente más cortos, y no se observaron diferencias entre pacientes con y sin HTR en cuanto al sexo, la edad al diagnóstico, el tipo de linfoma o el tipo de tratamiento recibido. Todos los pacientes con HTR se encontraban asintomáticos y las pruebas rutinarias de laboratorio no evidenciaron alteraciones. La TC y la GA-67 fueron altamente sugestivas de HTR. Ninguno de los pacientes con HTR tuvieron recurrencias y la HTR se resolvió espontáneamente en una mediana de 6 meses (rango: 4,0-11,0 meses). Conclusión: Se detectó HTR en alrededor del 50% de los niños con linfoma tras completarse el tratamiento. La evaluación clínica, pruebas de laboratorio, TC y gammagrafía con GA-67 resultan útiles para identificar la HTR y descartar otras lesiones en otras localizaciones


Introduction: Thymic regrowth after chemotherapy treatment has been reported in children with lymphoma, and in order to avoid misdiagnosing these cases as relapses, physicians should become familiar with rebound (reactive) thymic hyperplasia (RTH) and remain aware of its possible occurrence. We aimed to estimate the prevalence of RTH in children with lymphoma after completion of chemotherapy and to evaluate the clinical characteristics, outcomes, and the findings of computed tomography (CT) and gallium-67 (GA-67) scans in these patients. Patients and methods: We conducted a retrospective cross-sectional study by reviewing the health records of children with a lymphoma diagnosis managed at an outpatient paediatric oncology clinic in Jeddah, Saudi Arabia. Results: Rebound thymic hyperplasia was detected in 51.9% of the lymphoma patients (14/27). It developed a median of 2.5 months after completion of chemotherapy (range, 2.0-4.25 months). Patients with RTH had significantly shorter treatment durations, and we found no significant differences between patients with and without RTH in sex, age at diagnosis, type of lymphoma or type of treatment received. All patients with RTH were asymptomatic, and routine laboratory tests did not detect any abnormalities in them. The findings of CT and GA-67 scans were highly suggestive of RTH. None of the patients with RTH had a recurrence, and RTH resolved spontaneously within a median of 6 months (range, 4.0-11.0). Conclusion: RTH was detected in ∼50% of children with lymphoma after completion of chemotherapy. A clinical evaluation and laboratory tests combined with imaging by CT and GA-67 can help identify RTH and rule out other lesions elsewhere


Assuntos
Humanos , Masculino , Feminino , Pré-Escolar , Criança , Antineoplásicos/efeitos adversos , Linfoma/tratamento farmacológico , Hiperplasia do Timo/diagnóstico por imagem , Antineoplásicos/administração & dosagem , Estudos Transversais , Radioisótopos de Gálio/administração & dosagem , Prevalência , Estudos Retrospectivos , Arábia Saudita , Hiperplasia do Timo/epidemiologia , Hiperplasia do Timo/etiologia , Fatores de Tempo , Tomografia Computadorizada de Emissão
3.
Pharm. pract. (Granada, Internet) ; 17(2): 0-0, abr.-jun. 2019. tab
Artigo em Inglês | IBECS | ID: ibc-184687

RESUMO

Background: The role of Drug Information Center (DIC) in a health-care setting has increased tremendously owing to the high influx of pharmaceutical molecules that pose serious challenges to physicians. DIC promotes rational prescribing behavior among physicians, leading to better patient outcome. Objectives: This study aimed to explore information-seeking behaviors and awareness of physicians regarding DIC services in the Kingdom of Saudi Arabia. Methods: A cross-sectional study was conducted among physicians working in government and private sectors between June to November 2018 by using an 18-item electronic anonymous questionnaire. Descriptive and inferential statistics were performed using IBM SPSS (Version 21). A P-value of <0.05 was taken as the level of significance between responses. Results: In total, 500 questionnaires were distributed among the included hospitals, and only 254 physicians (response rate: 50.8%), including 193 males (76%), participated in the study. The majority of participants (n = 83, 32.7%) had more than ten years of experience, and many of the respondents (n=131) worked as residents. Most of the physicians (62.9%) were aware of their institutional DIC. UpToDate was the most preferred drug information database among physicians. Regarding the improvement required in the DIC services, most of the physicians (23.6%) opined that the contact details should be available in all clinical wards. Conclusions: Only 10% of the respondents were not aware of the presence of DIC at their institution. The UpToDate online drug information database was the most frequently used database by the physicians. Our findings showed that there is a need for conducting educational programs for physicians regarding DIC services. Such an attempt can increase the frequency of drug-related queries and promote patient safety


No disponible


Assuntos
Humanos , Serviços de Informação sobre Medicamentos/organização & administração , Acesso à Informação , Médicos/estatística & dados numéricos , Arábia Saudita/epidemiologia , Comportamento de Busca de Informação/classificação , Inquéritos e Questionários/estatística & dados numéricos
4.
Ars pharm ; 60(2): 125-131, abr.-jun. 2019. tab
Artigo em Espanhol | IBECS | ID: ibc-186016

RESUMO

Objective: The aim of this study was to study and assess the indications of acid suppressive drugs and to find out percentage of irrational prescriptions with acid suppressive drugs. Material/Methods: It is a prospective observational study conducted in the Armed Forces Hospitals Southern Region and Abha Maternity Hospital, both in Abha in Assir region (Saudi Arabia). The sample size of study was 185 patients. The case sheets of the patients' prescription order were reviewed for acid suppressive drugs prescription and relevant data was taken. Patients’ age above 18 were identified. The duration of study was 8 weeks, between May and June 2017. Results: Our results showed that the majority of the prescriptions of proton pump inhibitors (68.1%) were unjustifiable and that proton pump inhibitor was the most commonly prescribed acid suppressive drugs for the patients (97.8%). The frequency of prescribing for the autism spectrum disorders in our study was found to be higher in patients with an existing risk factor and was mostly recommended by physicians as concomitant medications (67.6%). The most common concomitant medications used with the proton pump inhibitors were non-steroidal anti-inflammatory drugs (29.2%) in which aspirin composed 13.5% of the non-steroidal anti-inflammatory drugs prescribed followed by antimicrobials (9.2%). Conclusion: Acid suppressive drugs are the most commonly prescribed drugs with no proper indications hence irrational. Based on the results of this study, creating awareness about reasonable use of acid suppressive drugs is a necessity


Objetivo: El objetivo de este estudio fue estudiar y evaluar las indicaciones de los medicamentos supresores de ácidos y averiguar el porcentaje de recetas irracionales con medicamentos supresores de ácidos. Material / Métodos: es un estudio observacional prospectivo realizado en los Hospitales de las Fuerzas Armadas del Sur y en el Hospital de Maternidad Abha, ambos en Abha en la región de Assir (Arabia Saudita). El tamaño muestral del estudio fue de 185 pacientes. Se revisaron las hojas de casos de orden de prescripción de los pacientes para la prescripción de medicamentos supresores de ácido y se tomaron los datos pertinentes. Se identificó la edad de los pacientes mayores de 18 años. La duración del estudio fue de 8 semanas, entre mayo y junio de 2017. Resultados: nuestros resultados mostraron que la mayoría de las prescripciones de inhibidores de la bomba de protones (68,1%) eran injustificables y que este era el fármaco supresor de ácido más comúnmente prescrito para los pacientes (97,8%). La frecuencia de prescripción para los trastornos del espectro autistas en nuestro estudio, fue mayor en pacientes con un factor de riesgo existente y fue recomendada principalmente por los médicos como medicamentos concomitantes (67,6%). Los medicamentos concomitantes más comunes que se usaron con los inhibidores de la bomba de protones fueron los antiinflamatorios no esteroideos (29.2%) en los cuales la aspirina supuso el 13,5% de los antiinflamatorios no esteroideos prescritos, seguidos por los antimicrobianos (9.2%). Conclusión: los medicamentos supresores de ácido son los medicamentos más comúnmente recetados sin indicaciones adecuadas, por lo que son irracionales. Basado en los resultados de este estudio, crear conciencia sobre el uso razonable de los medicamentos supresores del ácido es una necesidad


Assuntos
Humanos , Masculino , Feminino , Adolescente , Adulto Jovem , Adulto , Pessoa de Meia-Idade , Prescrições de Medicamentos/estatística & dados numéricos , Serviço de Farmácia Hospitalar , Agonistas dos Receptores Histamínicos/administração & dosagem , Inibidores da Bomba de Prótons/administração & dosagem , Ácidos/antagonistas & inibidores , Estudos Prospectivos , Arábia Saudita
5.
Span. j. psychol ; 22: e35.1-e35.8, 2019. tab
Artigo em Inglês | IBECS | ID: ibc-190186

RESUMO

In recent years postnatal depression (PND) has become one of the most important public health issues because of its prevalence. Estimates for those affected by PND suggest a range of 10-15% of new mothers worldwide. In the context of Saudi society, attitudes toward this disorder are influenced by various beliefs, traditions, cultural factors, and values. These variables trigger considerable disparity in terms of frequency of symptoms. The symptoms of postnatal depression vary and can arise over a period of months, causing profound effects on mothers, also effecting mother-baby and broader familial relationships. The current study establishes the rate of occurrence and risk factors for PND in the western region of Saudi Arabia, to build on existing data. In total, 217 new Saudi mothers were recruited and data was collected using the Edinburgh Postnatal Scale (EPDS) in conjunction with a self-report questionnaire. Based on recommendations in previous studies, an EPND cut-off point of 13 ≥ was applied herein. Findings show the prevalence of PND, approximately 17.1% among the participants, and contributing factors included a previous history of depression, χ2 = 67.74, df = 1, p < .05, problems with the child's health, χ2 = 31.42, df = 1, p < .05, issues with home support, χ2 = 43.47, df = 1, p < .05, and pregnancy complications, χ2 = 7.19, df = 1, p < .05. Meanwhile, no correlation was found between PND and the baby's gender, delivery type, breastfeeding, mother's age, or mother's educational level. Additional studies are required to confirm these findings, and to identify other risk factors


No disponible


Assuntos
Humanos , Feminino , Adulto Jovem , Adulto , Depressão Pós-Parto/epidemiologia , Depressão Pós-Parto/diagnóstico , Paridade , Prevalência , Fatores de Risco , Arábia Saudita/epidemiologia
6.
Pharm. pract. (Granada, Internet) ; 16(3): 0-0, jul.-sept. 2018. tab
Artigo em Inglês | IBECS | ID: ibc-174800

RESUMO

Background: Health literacy is an essential predictor of health status, disease control and adherence to medications. Objectives: The study goals were to assess the health literacy level of the general population in Saudi Arabia using translated Gulf Arabic version of the short-version of the Test of Functional Health Literacy in Adults (S-TOFHLA) and Single Item Literacy Screener (SILS) tests and to measure the relationship between health literacy and education level. Methods: The study was a cross-sectional with a convenience sample of 123 participants from the general population in Riyadh. Data were collected using the modified (Gulf) Arabic versions of both S-TOFHLA and SILS. Fisher's Exact test was used to measure the difference of the health literacy scores according to the education degrees and Cronbach's alpha was used to measure the internal consistency of the S-TOFHLA items. Results: More than half (55.4%) of the participants were male, 50.4% had a middle school or less education level, and we found that 84.4% had adequate health literacy as measured by the S-TOFHLA, compared to 49.6% as measured by SILS. The Fisher's Exact test showed a significant difference (P<.05) in the S-TOFHLA and SILS scores according to education categories. Conclusions: The level of education has a significant positive association with S-TOFHLA and SILS results. The Gulf Arabic version of S-TOFHLA is a reliable test with a good internal consistency and a significant positive correlation between the two parts of S-TOFHLA. We recommend the use of S-TOFHLA or SILS at the first patient visit


No disponible


Assuntos
Humanos , Publicações Periódicas como Assunto/estatística & dados numéricos , Manuscrito Médico , Traduções , Acesso à Informação , Troca de Informação em Saúde , Arábia Saudita/epidemiologia , Bases de Dados de Citações , Comparação Transcultural , Inquéritos e Questionários
7.
Pharm. pract. (Granada, Internet) ; 16(2): 0-0, abr.-jun. 2018. tab
Artigo em Inglês | IBECS | ID: ibc-174794

RESUMO

Background: There is a dearth of literature on perceptions of preparedness to practise, which explores the extent to which educational institutions prepare their students to fulfil their professional role. Objective: The aim of this study was to explore perceptions of preparedness to practise among Saudi Arabian pharmacy graduates working in hospital. Method: Face-to-face, semi-structured interviews were conducted with ten hospital pharmacists based in four hospitals in the Eastern Province of Saudi Arabia who had qualified within the last five years from a Saudi Arabian School of Pharmacy. Interviews focused on expectations of hospital practise, perceptions of preparedness and challenges encountered, and reflections on how to better prepare students. Interviews were audio-recorded, transcribed and analysed thematically by two independent researchers using the Framework Approach. Results: Five key themes were identified: expectations versus reality of practise; issues relating to university course; practice related training; adapting to the work environment; and proposed improvements to undergraduate education. Participants were generally disappointed to find practise was not as expected. University training was largely didactic, with skills such as critical thinking not being sufficiently developed. Where practice related training was provided, it was variable in length and content. Cultural issues, most notably working in a mixed sex environment, were also considered to impact preparedness. Suggested improvements included greater focus on skills development and structured training placements. Conclusions: Participants experiences in university, and experiential placements varied greatly and were perceived to impact greatly on preparedness to practise. Further multiple perspective exploration of perceptions of preparedness to practise is warranted


No disponible


Assuntos
Humanos , Educação em Farmácia/tendências , Avaliação Educacional/métodos , Prática Profissional/tendências , Arábia Saudita/epidemiologia , Capacitação Profissional , Currículo/tendências , Competência Profissional , Pesquisa Qualitativa
8.
Pharm. pract. (Granada, Internet) ; 15(1): 0-0, ene.-mar. 2017. tab
Artigo em Inglês | IBECS | ID: ibc-161872

RESUMO

Background: Medication reconciliation is a major component of safe patient care. One of the main problems in the implementation of a medication reconciliation process is the lack of human resources. With limited resources, it is better to target medication reconciliation resources to patients who will derive the most benefit from it. Objective: The primary objective of this study was to determine the frequency and types of medication reconciliation errors identified by pharmacists performing medication reconciliation at admission. Each medication error was rated for its potential to cause patient harm during hospitalization. A secondary objective was to determine risk factors associated with medication reconciliation errors. Methods: This was a prospective, single-center pilot study conducted in the internal medicine and surgical wards of a tertiary care teaching hospital in the Eastern province of Saudi Arabia. A clinical pharmacist took the best possible medication history of patients admitted to medical and surgical services and compared with the medication orders at hospital admission; any identified discrepancies were noted and analyzed for reconciliation errors. Multivariate logistic regression was performed to determine the risk factors related to reconciliation errors. Results: A total of 328 patients (138 in surgical and 198 in medical) were included in the study. For the 1419 medications recorded, 1091 discrepancies were discovered out of which 491 (41.6%) were reconciliation errors. The errors affected 177 patients (54%). The incidence of reconciliation errors in the medical patient group was 25.1% and 32.0% in the surgical group (p<0.001). In both groups, the most frequent reconciliation error was the omission (43.5% and 51.2%). Lipid-lowering (12.4%) and antihypertensive agents were most commonly involved. If undetected, 43.6% of order errors were rated as potentially requiring increased monitoring or intervention to preclude harm; 17.7% were rated as potentially harmful. A multivariate logistic regression model showed that patients aged ≥65 years, polypharmacy, and prescriptions for hypoglycemic drugs and warfarin were more likely associated with reconciliation errors. Conclusion: There is a high failure rate in medication reconciliation process in patients admitted to the medical and surgical department. The reconciliation process proves to be a useful tool since nearly half of avoided reconciliation errors were unintentional and had the potential for harm. This strategy, based on our results and the difficulty of applying the process to all patients should be directed primarily to the patients at increased risk of error (AU)


No disponible


Assuntos
Humanos , Masculino , Feminino , Erros de Medicação/efeitos adversos , Erros de Medicação/prevenção & controle , Tratamento Terciário/métodos , Fatores de Risco , Farmacoepidemiologia/métodos , Arábia Saudita/epidemiologia , Estudos Prospectivos , Modelos Logísticos , Análise Multivariada , Estudos Transversais/métodos
9.
Clin. transl. oncol. (Print) ; 18(2): 144-152, feb. 2016. tab
Artigo em Inglês | IBECS | ID: ibc-148219

RESUMO

Objective. In this cross-sectional study, we aimed to describe the quality of life of Saudi colorectal cancer (CRC) patients and identify the factors that may further improve health care for CRC survivors in Saudi Arabia (KSA). Methods. A total of 106 CRC patients from five different private and public tertiary level hospitals in Saudi Arabia participated in this study. CRC patient was interviewed by a trained researcher between September and December 2014. All respondents answered a three-part questionnaire which includes demographic data and a validated Arabic version of the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life. Results. Participants had a mean score for global health of 67.1 (95 % CI 62.55-71.71). Among the five scales of quality of life, social functioning and functional scales of CRC patients scored the highest [Mean 83.49 (95 % CI 78.64-86.33)] while the lowest scored was emotional scales [66.9 (95 % CI 61.81-71.98)]. Insomnia was considered the most distressing symptom on the symptom scales. Using the disease-specific tool, it was found that sexual interest scored the highest. On the symptom scale, dissatisfaction with stoma care problems scored the highest. Conclusion. Factors associated with a major reduction in all domains of quality of life included employment status and tumor location. This study identifies the factors and issues that affect the quality of life of CRC patients in KSA. Addressing these factors and issues may lessen the burden of cancer survivors in the KSA or may prolong their survival (AU)


No disponible


Assuntos
Humanos , Masculino , Feminino , Neoplasias Colorretais/metabolismo , Neoplasias Colorretais/patologia , Arábia Saudita/etnologia , Estudos Transversais/métodos , Náusea/diagnóstico , Terapêutica/métodos , Neoplasias Colorretais/tratamento farmacológico , Neoplasias Colorretais/radioterapia , Qualidade de Vida/psicologia , Estudos Transversais , Náusea/complicações , Intervalo Livre de Doença , Comportamento Social , Terapêutica/instrumentação
10.
Ars pharm ; 56(2): 109-114, abr.-jun. 2015. tab
Artigo em Inglês | IBECS | ID: ibc-139447

RESUMO

Background. Hypertension is extremely prevalent in patients with diabetes. Limited data exist on utilization patterns of antihypertensive in this population are consistent with evidence-based practice guidelines. Objective. To evaluate utilization patterns of antihypertensive agents among diabetic patients with hypertension. Design. retrospective descriptive cross sectional. Patients / Participants. 149 patients with diabetes and hypertension from outpatient department at Family Medicine Hospital, Ahaderfieda. Khamis Mushait, K.S.A. Results. Over 43% of patients were receiving calcium channel blockers (CCB), 36.2 % of received angiotensin converting enzyme inhibitors (ACEI), followed by angiotensin receptor blockers (ARBs) (34.9%), diuretics (34.2%) and Beta-blockers (16.2%). Patients on monotherapy were mostly receiving CCB (34.3%) and ACEI (29.9%). The majority (55.03%) of treated patients were on multidrug regimens. In patients with coronary artery disease (CAD), a diuretic with ACEI (25%) and calcium hannel blocker with angiotensin receptor blocker (25%) was most commonly prescribed. Conclusions. Patterns of antihypertensive therapy were generally consistent with international guidelines. Areas of improvement include increasing ACEI/ARB and diuretic use, decreasing the number of untreated patients, and increasing the proportion of patients with controlled BP in this population


Antecedentes. La hipertensión es muy frecuente en los pacientes con diabetes. Existen datos limitados sobre los patrones de utilización de antihipertensivos en esta población consistentes con las guías de práctica basadas en la evidencia. Objetivo. Evaluar los patrones de utilización de antihipertensivos en los pacientes diabéticos con hipertensión Diseño. Estudio retrospectivo descriptivo transversal. Pacientes / Participantes. 149 pacientes con diabetes e hipertensión, del departamento de pacientes ambulatorios en el Hospital de Medicina Familiar, Ahaderfieda. Khamis Mushait, K.S.A. Resultados. Más del 43% de los pacientes estaban recibiendo bloqueadores del canal de calcio (CCB), el 36,2% recibían inhibidores de la enzima convertidora de angiotensina (IECA), seguido de los bloqueadores de los receptores de angiotensina (BRA) (34,9%), diuréticos (34,2%) y bloqueadores β (16,2 %). Los pacientes en monoterapia fueron la mayoría recibiendo CCB (34,3%) e IECA (29,9%). La mayoría (55,03%) de los pacientes tratados se encontraban en regímenes de múltiples fármacos. En los pacientes con enfermedad de la arteria coronaria (CAD), se les prescribió con mayor frecuencia diurético con IECA (25%) y bloqueador de canales de calcio con bloqueador del receptor de angiotensina (25%). Conclusiones. Los patrones de utilización de antihipertensivos fueron generalmente consistentes con las directrices internacionales. Las áreas de mejora incluyen el aumento de IECA / ARB y el uso de diuréticos, disminuyendo el número de pacientes no tratados, y el aumento de la proporción de pacientes con PA controlada en esta población


Assuntos
Feminino , Humanos , Masculino , Ansiolíticos/administração & dosagem , Ansiolíticos/farmacologia , Diabetes Mellitus Tipo 2/metabolismo , Diabetes Mellitus Tipo 2/patologia , Pacientes Ambulatoriais/classificação , Arábia Saudita/etnologia , Bloqueadores do Canal de Sódio Epitelial , Bloqueadores do Canal de Sódio Epitelial/farmacologia , Ansiolíticos , Ansiolíticos/toxicidade , Diabetes Mellitus Tipo 2/sangue , Diabetes Mellitus Tipo 2/prevenção & controle , Pacientes Ambulatoriais/psicologia , Bloqueadores do Canal de Sódio Epitelial/administração & dosagem , Bloqueadores do Canal de Sódio Epitelial/uso terapêutico
11.
Ars pharm ; 53(4): 28-31[4], oct.-dic. 2012. ilus, graf
Artigo em Inglês | IBECS | ID: ibc-107846

RESUMO

Objetivo: Los fallos de medicación, generalmente definidos como cualquier error en el asesoramiento, distribución o manejo de un tratamiento, sin importar si dichos errores conllevan sanciones o no, son la causa más inevitable de mal tratamiento en el paciente. Las tasas de errores de medicación estudiadas son muy variables, como resultado de la alta variedad de definiciones y métodos de estudio utilizados. Miles de personas mueren en el mundo cada año debido a errores de prescripción lo que supone un gasto anual de miles de millones de dólares. El presente estudio se llevó a cabo en el departamento de Farmacia Práctica, Facultad de Farmacia Clínica, Universidad de King Faisal, Al-Ahsa, Arabia Saudí del 1 de Octubre de 2010 al 31 de Diciembre de 2011 con el objetivo de investigar errores de prescripción. Material y método: Las prescripciones fueron recogidas de diferentes hospitales de la región este de Arabia Saudí y fueron analizadas en el departamento de Farmacia Práctica, Facultad de Farmacia Clínica. La información de las prescripciones fue analizada estadísticamente. Resultados: Se procesaron un total de 500 prescripciones. Tras la evaluación se detectaron errores fatales como edad (4,6%), peso (98,8%), diagnóstico (30%), o dosificación (14,6%), que no fueron notificados. Se detectaron errores adicionales e inconsistencias en las prescripciones estudiadas. Conclusión: Es necesario una revisión en profundidad de los sistemas gubernamentales para el control de los errores de prescripción en Al-Ahsa, Arabia Saudí(AU)


Aims: Medication faults, broadly defined as any error in the advising, distributing, or management of a treatment, nevertheless whether such mistakes lead to confrontational penalties or not, are the single most inevitable cause of patient maltreatment. Incidences of medication error rates vary widely, as a result of the variety of altered study methods and descriptions used. Several thousand individuals are dying in the world because of the prescription errors every year, at the same time these errors cost billions of dollars annually. This study was conducted in the department of Pharmacy Practice, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Saudi Arabia from 1st October 2010 to 31st December 2011, to investigate the prescriptions regarding errors. Materials and Methods: The prescriptions were collected from different hospitals of Eastern region of Saudi Arabia and analyzed in the department of Pharmacy Practice College of Clinical Pharmacy Al-Ahsa. The information in the prescriptions was evaluated statistically. Results: A total of 500 prescriptions were processed. In evaluation it was found that out of 500 prescriptions were having fatal errors like age (4.6%), weight (98.8%), Diagnosis (30%), Dosage (14.6%), were not declared. Along with that a number of errors and inconsistencies were noticed in the prescriptions studied. Conclusion: There is need of a comprehensive review of the government’s control system on prescription error in Al-Ahsa, Saudi Arabia(AU)


Assuntos
Humanos , Prescrição Inadequada/estatística & dados numéricos , Erros Médicos/estatística & dados numéricos , Prescrições de Medicamentos/estatística & dados numéricos , Arábia Saudita/epidemiologia , Estatísticas Hospitalares
12.
Gac. sanit. (Barc., Ed. impr.) ; 26(3): 251-255, mayo-jun. 2012. ilus, tab
Artigo em Espanhol | IBECS | ID: ibc-111273

RESUMO

Introducción La peregrinación religiosa a Arabia Saudí o Hajj es un precepto básico en la doctrina islámica. Anualmente millones de peregrinos (un 5% procedente de la Unión Europea) se concentran en La Meca después del Ramadán, con los riesgos sanitarios que eso conlleva. Métodos Estudio observacional y prospectivo de una cohorte de peregrinos atendidos en visita de actividades preventivas predesplazamiento en la Unidad de Salud Internacional Metropolitana Norte (Santa Coloma de Gramenet, Barcelona, España) durante 2009-2010.ResultadosSe valoraron 193 peregrinos (135 hombres, 69,9%), con una edad media (DE) de 37,1 (16,9) años. Eran inmigrantes 176 (91,2%), originarios de Pakistán (54,9%), Marruecos (29%), Bangladesh (4,1%) y otros (7,2%). Se desplazaban a Arabia Saudí por una media (DE) de 16,3 (9,2) días; optaban por la peregrinación larga (Hajj) 80 (41,5%) y por la corta (Umra) 113 (58,5%). Presentaban antecedentes patológicos 29 (15%). Se obtuvo una cobertura vacunal superior al 75% para tétanos-difteria, antineumocócica y antimeningocócica tetravalente, y sólo de un 70,4% para la antigripal. Presentaron algún problema de salud 41 (13,5%), el 61% de ellos síntomas de vías respiratorias. Los factores de riesgo independientemente relacionados con presentar enfermedades fueron los días de estancia (odds ratio [OR]=1,06; intervalo de confianza del 95% [IC95%]: 1,01-1,11) y realizar el Hajj frente a la Umra (OR=1,08; IC95%: 1,07-1,12).Conclusiones Los peregrinos a Arabia Saudí procedentes de España son un colectivo fundamentalmente joven y sano. Presentaron un mayor número de enfermedades aquellos con estancias más largas (AU)


Introduction Religious pilgrimage to Saudi Arabia, or Hajj, is a basic tenet of the Islamic doctrine and, after Ramadan, annually represents the largest human concentration (with up to 5% of from the EU) around the world. Such a gathering entails health risks. Methods A prospective observational study was conducted of a cohort of pilgrims attended for pre-travel preventive activities in the North Metropolitan International Health Unit (Santa Coloma de Gramenet, Barcelona, Spain) from 2009-2010.ResultsA total of 193 pilgrims were assessed and 135 (69.9%) were men. Their mean age (SD) was 37.1 (16.9) years. Among the pilgrims, 176 (91.2%) were immigrants, mainly from Pakistan (54.9%), Morocco (29%), Bangladesh (4.1%) or other countries (7.2%). The pilgrims stayed in Saudi Arabia a mean (SD) of 16.3 (9.2) days. Eighty (41.5%) opted for the 1 month-long pilgrimage (Hajj) and 113 (58.5%) for the shorter Umra. One or more pathological antecedent was recorded in 29 (15%). Vaccination coverage was >75% for tetanus-diphtheria, pneumococcal and quadrivalent meningitis but was only 70.4% for influenza. After returning, 41 (13.5%) pilgrims reported some health problem; of these, 61% were respiratory tract symptoms. The risk factors independently correlated with the presence of diseases was the number of days in Saudi Arabia (OR=1.06; 95% CI: 1.01-1.11) and taking part in the Hajj compared with the Umra (OR=1.08; 95% CI: 1.07-1.12).Conclusions Religious pilgrims from Spain to Saudi Arabia are mainly young and healthy. Those with longer stays abroad contracted a higher number of diseases (AU)


Assuntos
Humanos , Caminhada , Doenças Transmissíveis/epidemiologia , Aglomeração , Arábia Saudita/epidemiologia , Fatores de Risco , Islamismo , Vacinação , Certificado Internacional de Vacinação ou Profilaxia , Controle Sanitário de Viajantes
13.
Av. diabetol ; 26(1): 29-35, ene.-feb. 2010. tab, graf
Artigo em Inglês | IBECS | ID: ibc-83213

RESUMO

Diabetes is one of the growing health problems in the Middle East region ingeneral and Saudi Arabia in particular. The increasing number of the populationand changes in the pattern of life in the region expose a large number of thepopulation to diabetes and its complications. The following review discussesthe magnitude of the diabetes problem in Saudi Arabia, diabetic peripheralneuropathy, diabetic arterial disease, diabetic foot and the impact of educationto prevent diabetic foot diseases on the outcome of diabetic foot problems.According to my knowledge, this is the first review which shows the magnitudeof diabetic foot problems and its risk factors in Saudi Arabia(AU)


Assuntos
Humanos , Diabetes Mellitus/epidemiologia , Pé Diabético/epidemiologia , Arábia Saudita/epidemiologia , Angiopatias Diabéticas/epidemiologia , Neuropatias Diabéticas/epidemiologia
15.
Enferm. emerg ; 7(2): 120-124, abr.-jun. 2005. tab
Artigo em Espanhol | IBECS | ID: ibc-67196

RESUMO

Objetivo: 1. Caracterizar a los viajeros que se desplazan a Arabia Saudita con motivo de la peregrinación a los lugares santos islámicos (Hajj o Umra) y, 2. Determinar el riesgo del viaje en relación a una cohorte de inmigrantes viajeros a sus países de origen. Población y método: Se analizan datos procedentes de peregrinos (grupo H) durante el periodo 06/99-01/03 y se comparan con un grupo de inmigrantes viajeros consultantes durante el mismo periodo (grupo IV).Resultados: En el grupo H fueron identificados 23 viajeros-inmigrantes 15 (65,2%) y españoles 8 (34,8%)- .Tomaron parte en la Umra 13 (56,5%) y en el Hajj 10(43,5%). Habían residido por periodos > 2 años en Europa 19 (82,6%; IC95%: 67,3-97,9) y visitaron otro país 7 (30,4%). No se hallaron diferencias significativas entre los grupos H e IV en cuanto a días de duración del viaje y nº de viajes de riesgo. Los viajeros del grupo IV consultaron con mayor frecuencia en periodos < 15 días previos a la partida (p<0,001), lo que ello sugiere la existencia de mayor planificación y conocimiento de actividades preventivas del grupo H. Presentaron algún problema de salud el 8,6% del los viajeros del grupo H y el 23,1% del grupo IV. Conclusiones: Una parte sustancial de los peregrinos es de origen autóctono. Los peregrinos presentaron factores de riesgo para el desarrollo de problemas de salud en una proporción similar a la que presentan los inmigrantes que visitan sus países de origen (AU)


Objectives: 1. To characterize travelling people fulfilling the mandatory islamic obligation to visit the holy places in Saudi Arabia (Hajj or Umra) and, 2. To determine the risk of travel compared with a travelling immigrant to native country cohort. Method: Data recorded from travellers consulting to carryout some kind of pilgrimage to Saudi Arabia (group H)from 06/99 to 01/03 are analyzed and they were compared with a group of travelling immigrants during the same period (group IV).Results: In the group H 23 travellers were identified, of whom they were immigrants 15 (65.2%) and Spanish 8(34.8%). They carried out Umra 13 (56.5%) and Hajj10 (43.5%). They resided during periods > 2 years in Europe 19 (82.6%; IC 95%: 67.3-97.9) and they visited further countries 7 (30.4%). There where not significant differences between groups H and IV concerning lenght of journey and number of considered risk travels. Travellers from group IV consulted most frequently in periods < 15days prior to the journey (p<0.001), which suggests the existence of better planning and knowledge about pretravel preventive measures among group H. Any health problem abroad was recorded in 8.6% of group H and23.1% of group IV. Conclusions: A substantial part of islamic pilgrims have yet a spanish-native origin. Travelling pilgrims displayed risk factors to develop health problems in a similar proportion to which display the immigrants who visit their native countries (AU)


Assuntos
Humanos , Migrantes/estatística & dados numéricos , Doenças Transmissíveis/epidemiologia , Viagem , Inquéritos de Morbidade , Fatores de Risco , Emigração e Imigração/estatística & dados numéricos , Arábia Saudita/epidemiologia
16.
Allergol. immunopatol ; 30(4): 225-231, jul. 2002.
Artigo em Inglês | IBECS | ID: ibc-15981

RESUMO

Objective: Determination of the urinary concentration of eosinophil protein X (U-EPX) may objectively predict the severity and activity of asthma in children. Methods: Concentrations of U-EPX in 80 non- atopic asthmatic children were compared with those in 25 healthy control children. The patients were studied during attacks and two weeks later. The severity of asthma attacks was determined according to a pre-existing score. U-EPX was measured by the specific radioimmunoassay technique (Pharmacia, Uppsala, Sweden). This measurement was correlated with the clinical and radiological investigations as well as with other variables such as blood oxygen saturation, peak expiratory rate and eosinophil count. Results: U-EPX concentrations were significantly higher in all asthmatic children during attacks (139.6 ± 11.7 μg/mmol of creatinine) than those in the control group (35.3 ± 6.2 μg/mmol of creatinine) (p < 0.001). Two weeks after resolution of the exacerbation, U-EPX significantly decreased (66.5 ± 9.3 μg/mmol of creatinine) (p < 0.001). U-EPX concentrations were highest in patients with severe attacks (191.5 ± 11.3 μg/mmol of creatinine) (p < 0.001). No statistically significant differences were found between mild (88.2 ± 7.2 μg/mmol of creatinine) and moderate attacks (119.6 ± 8.5 μg/mmol of creatinine). At the two-week follow-up, U-EPX concentrations in patients with mild or moderate attacks was similar to those in controls but were persistently elevated in the subgroup with severe attacks (103.8 ± 9.4 μg/mmol of creatinine) (p < 0.001). No significant correlation was found between U-EPX concentrations and blood oxygen saturation, peak expiratory rate or eosinophil count. Conclusion: A statistically significant correlation was found between U-EPX concentrations and the severity of attacks in asthmatic children. This substance could be useful in quantifying bronchial inflammation. This result could further be used as a marker of severity of disease exacerbation and would not only facilitate early diagnosis and staging of inflammatory and allergic disorders but would also allow therapy and interventions to be monitored (AU)


Objetivo: La determinación de la concentración urinaria de proteína X de los eosinófilos (U-EPX) puede predecir de manera objetiva la intensidad y la actividad del asma infantil. Métodos: Se compararon las concentraciones de U-EPX de 80 niños asmáticos no atópicos con las de 25 niños de control sanos. Se estudió a los pacientes durante las crisis y dos semanas más tarde. La intensidad de las crisis asmáticas se determinó con arreglo a una puntuación previa. La U-EPX se midió mediante una técnica específica de radioinmunoanálisis (Pharamacia, Uppsala, Suecia). Esta medición se correlacionó con los estudios clínicos y radiológicos y con otras variables, como la saturación sanguínea de oxígeno, la frecuencia espiratoria máxima y el recuento de eosinófilos. Resultados: Las concentraciones de U-EPX fueron significativamente mayores en todos los niños asmáticos durante las crisis (139,6 ñ 11,7 g por mmol de creatinina) que en el grupo de control (35,3 ñ 6,2 g/mmol de creatinina) (p < 0,001). Dos semanas después de la resolución de la reagudización, la U-EPX disminuyó de modo significativo (66,5 ñ 9,3 g/mmol de creatinina) (p < 0,001). Las concentraciones de U-EPX fueron máximas en los pacientes con crisis graves (191,5 ñ 11,3 g/mmol de creatinina) (p < 0,001). No se observaron diferencias estadísticamente significativas entre las crisis leves (88,2 ñ 7,2 g/mmol de creatinina) y las moderadas (119,6 ñ 8,5 g/mmol de creatinina). A las dos semanas de seguimiento, las concentraciones de U-EPX de los pacientes con crisis leves o moderadas eran parecidas a las de los testigos, pero se mantenían persistentemente elevadas en el subgrupo con crisis graves (103,8 ñ 9,4 g/mmol de creatinina) (p < 0,001). No hubo una correlación significativa entre las concentraciones de U-EPX y la saturación sanguínea de oxígeno, la frecuencia espiratoria máxima o el recuento de eosinófilos. Conclusión: Se observó una correlación estadísticamente significativa entre las concentraciones de U-EPX y la intensidad de las crisis de niños asmáticos. Esta sustancia podría ser útil para cuantificar la inflamación bronquial. Este resultado se podría emplear también como marcador del grado de reagudización de la enfermedad y no solo facilitaría un diagnóstico y una estadificación precoces de los trastornos alérgicos e inflamatorios, sino que permitiría también controlar las intervenciones y el tratamiento (AU)


Assuntos
Pré-Escolar , Criança , Masculino , Feminino , Humanos , Arábia Saudita , Ribonucleases , Antiasmáticos , Oxigênio , Asma , Creatinina , Doença Aguda , Albuterol , Hipersensibilidade Imediata , Contagem de Leucócitos , Eosinófilos , Seguimentos , Índice de Gravidade de Doença , Pico do Fluxo Expiratório
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