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1.
Allergol. immunopatol ; 48(2): 202-210, mar.-abr. 2020. tab, ilus
Artigo em Inglês | IBECS | ID: ibc-191826

RESUMO

Cow's milk protein allergy (CMPA) is the most common type of food-allergy in younger children. Prognosis is usually good, with most children developing tolerance before school age. Children may present with a wide spectrum of symptoms that range from mild to severe; skin reactions such as angioedema and urticaria and gastrointestinal symptoms are the most common presentations of CMPA. Approximately one-third of CMPA patients suffer from multiple food-allergies; severe conditions such as anaphylactic shock (9%), eosinophilic esophagitis (4.7%), and food-protein induced enterocolitis (1%) may also develop in some children. Timely and accurate diagnosis and management is essential for proper growth and development of children with CMPA. In this expert consensus report, we aimed to adapt current understandings in the CMPA field to the specific conditions in Turkey and health system to help physicians with their day-to-day decision making


No disponible


Assuntos
Humanos , Criança , Hipersensibilidade a Leite/diagnóstico , Consenso , Hipersensibilidade a Leite/epidemiologia , Prognóstico , Hipersensibilidade a Leite/imunologia , Turquia/epidemiologia , Hipersensibilidade Imediata/diagnóstico
2.
Enferm. clín. (Ed. impr.) ; 30(1): 37-41, ene.-feb. 2020. tab
Artigo em Espanhol | IBECS | ID: ibc-186282

RESUMO

Objetivo: El agotamiento emocional puede afectar a la actitud de las enfermeras sobre la seguridad del paciente, debido a las consecuencias adversas que genera, pudiendo provocar errores clínicos. El objetivo del presente estudio es identificar el nivel de agotamiento emocional de las enfermeras pediátricas y determinar la relación entre las actitudes de seguridad del paciente y el agotamiento. Método: Estudio observacional descriptivo transversal desarrollado entre enero y julio de 2016 en el Hospital Infantil Universitario Ege, situado en Esmirna (Izmir, Turquía). Los datos se recopilaron utilizando el Cuestionario de características sociodemográficas, el Inventario de agotamiento de Maslach y el Cuestionario de actitud de seguridad del paciente. Se analizaron los datos con el programa SPSS. Se contó con el visto bueno del comité de ética correspondiente. Resultados: La tasa de respuesta fue del 60%, con un total de 104 participantes. Se identificó agotamiento emocional en más de la mitad de las enfermeras participantes, con una correlación negativa entre la actitud sobre la seguridad del paciente y el agotamiento emocional. Se encontró una correlación positiva entre las puntuaciones del Cuestionario de actitud de seguridad del paciente y las puntuaciones de la subescala de Logro personal. Se encontró que la puntuación de agotamiento emocional aumentó a medida que disminuyó la actitud de seguridad del paciente. También se encontró que las puntuaciones de la subescala de Logro personal y las puntuaciones de actitudes de seguridad del paciente aumentaron. Conclusión: Existe una relación entre los niveles de agotamiento emocional de las enfermeras y una disminución de las actitudes hacia la seguridad, al mismo tiempo que el logro personal contribuye a mejorar la actitud hacia la seguridad del paciente


Aim: Burnout can affect nurses' patient safety-related attitudes due to adverse conditions it creates in nurses and can lead to medical errors. The purpose of this research is to determine the relationship between the patient safety attitudes and pediatric nurses' burnout. Method: Observational, descriptive and cross-sectional study, carried out between January and July 2016 at Ege University Children's Hospital in İzmir (Turkey). Data was collected using the Sociodemographic Characteristics Questionnaire, the Maslach Burnout Inventory and the Patient Safety Attitude Questionnaire. The data was analysed with the program SPSS. Permission was obtained from the corresponding Ethical Committee. Results: The response rate was 60%, with a total of 104 participants. Emotional exhaustion was identified in more than half of the participating nurses, with a negative correlation between the attitude towards patient safety and emotional exhaustion. A positive correlation was found between the scores of the Patient Safety Attitude Questionnaire and the scores of the Personal achievement subscale. It was found that the emotional exhaustion score increased as the patient's safety attitude decreased. It was also found that Personal Achievement subscale scores and safety attitude scores of the patient increased. Conclusion: There is a relationship between the levels of emotional exhaustion of nurses and a decrease in attitudes towards safety, at the same time as personal achievement helps to improve the attitude towards patient safety


Assuntos
Humanos , Esgotamento Psicológico/enfermagem , Segurança do Paciente , Atitude do Pessoal de Saúde , Turquia , Inquéritos e Questionários , Estudos Transversais , Satisfação no Emprego
3.
Actas urol. esp ; 44(1): 27-33, ene.-feb. 2020. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-192788

RESUMO

INTRODUCCIÓN: Sunitinib (SUN) y pazopanib (PAZ) son 2 inhibidores orales de la tirosina cinasa que actúan contra el factor de crecimiento endotelial vascular. Su eficacia y seguridad en el carcinoma de células renales metastásico se ha demostrado con estudios de fase III. Sin embargo, la evidencia real es escasa. El objetivo de este análisis es evaluar el beneficio clínico de SUN y PAZ en la práctica clínica habitual. MÉTODOS: Revisamos los registros médicos de 79 pacientes con carcinoma de células renales metastásico tratados con SUN (50 mg/día en el régimen 4/2) o PAZ (800 mg/día continuo). Los pacientes fueron evaluados retrospectivamente en 2 hospitales turcos entre 2006 y 2016. RESULTADOS: La mediana de edad de toda la cohorte fue de 60 (28-87) años y el 70% de ellos eran hombres. La tasa de respuesta objetiva y la tasa de control de la enfermedad en los grupos SUN/PAZ fueron 34/37% (p = 0,96) y 78/87% (p = 0,046), respectivamente. Con una mediana de seguimiento de 15 meses, las medianas de supervivencia libre de progresión y de supervivencia global en los grupos SUN/PAZ fueron de 8/8 meses (p = 0,83) y 22/21 meses (p = 0,53), respectivamente. La toxicidad común entre SUN vs. PAZ incluía fatiga (59 vs.74%), cambios en la piel (44 vs.44%), anemia (35 vs.42%), hipotiroidismo (37 vs.19%; p = 0,02) e hipertensión (33 vs.50%). En los pacientes tratados con SUN, la toxicidad total de grado 3-4 (número medio de eventos tóxicos por paciente) fue de 0,71, mientras que en los pacientes tratados con PAZ, la toxicidad total de grado 3-4 fue de 0,11 (p < 0,001). SUN se asoció con una mayor incidencia de fatiga de grado 3-4 (p = 0,007), anemia (p = 0,001) e hipotiroidismo, requiriendo tratamiento (p = 0,02). Fue necesario reducir la dosis en los grupos SUN y PAZ en el 49 y el 24% de los pacientes (p = 0,02), y el cese del tratamiento en el 37 y el 26% de los pacientes (p = 0,37), respectivamente. CONCLUSIONES: En nuestro estudio no hubo diferencias en términos de supervivencia entre los 2 agentes. Sin embargo, en los pacientes tratados con SUN se dieron más eventos adversos de grado 3-4, siendo necesaria la reducción de la dosis


INTRODUCTION: Sunitinib (SUN) and pazopanib (PAZ) are 2 oral tyrosine kinase inhibitors against vascular endothelial growth factor. Their efficacy and safety in metastatic renal cell carcinoma has been proven with phase III studies. However, real world data is limited. The objective of this study is to assess the clinical benefit of SUN and PAZ in routine practice. METHODS: We reviewed the medical records of 79 metastatic renal cell carcinoma patients treated with SUN (50 mg/day on 4/2-schedule) or PAZ (800 mg/day continuously). Patients were assessed retrospectively at 2 Turkish hospitals between 2006 and 2016. RESULTS: For the entire cohort median age of patients was 60 (28-87) years and 70% of them were male. The objective response rate and disease control rate in SUN/PAZ groups were 34/37% (P = .96) and 78/87% (P = .046), respectively. With a median follow up duration of 15 months, median progression-free survival and overall survival in SUN/PAZ groups were 8/8 months (P = .83) and 22/21 months (P = .53), respectively. The common all grade toxicities for SUN vs. PAZ were fatigue (59 vs.74%), skin changes (44 vs.44%), anemia (35 vs.42%), hypothyroidism (37 vs.19%; P = .02) and hypertension (33 vs.50%). In patients treated with SUN, total grade 3-4 toxicities (mean number of toxic events per patients) were 0.71, whereas in patients treated with PAZ, total grade 3-4 toxicities were 0.11 (P < .001). SUN was associated with an increased incidence of grade 3-4 fatigue (P = .007), anemia (P = .001) and hypothyroidism that needed therapy (P = .02). Dose reduction in 49 and 24% of patients (P = .02), and treatment cessation in 37 and 26% of patients (P = .37) were required in the SUN and PAZ groups, respectively. CONCLUSIONS: In our study, there was no difference in terms of survival outcomes between 2 agents. However, patients treated with SUN had more grade 3-4 adverse events which prompted dose reduction


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Carcinoma de Células Renais/tratamento farmacológico , Sunitinibe/uso terapêutico , Antineoplásicos/uso terapêutico , Inibidores de Proteínas Quinases/uso terapêutico , Metástase Neoplásica , Resultado do Tratamento , Análise de Sobrevida , Estudos Retrospectivos , Turquia
4.
An. psicol ; 36(1): 111-121, ene. 2020. graf, tab
Artigo em Inglês | IBECS | ID: ibc-192047

RESUMO

Adolescence is a critical period of growth and development in an individual's life cycle. Because of the importance of developmental success during this stage, with implications of adult development and positive mental health, the current study aims to investigate the predictor roles of cognitive flexibility and self-efficacy on mental well-being of Turkish adolescents. Moreover, as the association between cognitive flexibility and self-efficacy are considered to have crucial effects on adolescents' mental well-being, it was supposed that academic, social and emotional self-efficacy could mediate the relation between cognitive flexibility and mental well-being. The participants of the research are comprised of 192 females (%49) and 200 males (%51), a total of 392 high school students who were attending four different high schools enrolled in grades 9-12, in a city of Turkey. Cognitive Flexibility Inventory, The Self-Efficacy Scale for Children and Warwick-Edinburgh Mental Well-Being Scale were applied in data collection. The results showed that cognitive flexibility positively correlated with sub-dimensions of self-efficacy and mental well-being. Also, sub-dimensions of self-efficacy positively correlated with mental well-being. Findings from the mediational model indicated that academic, social and emotional self-efficacy served to mediate the relationship between cognitive flexibility and mental well-being. Research findings were discussed in the light of the literature and some suggestions were proposed for mental health experts and researchers


La adolescencia es una etapa crítica de crecimiento y desarrollo en el ciclo de vida de un individuo. Debido a la importancia del éxito en el desarrollo durante esta etapa, con implicaciones del desarrollo adulto y la salud mental positiva, el presente estudio tiene como objetivo examinar los roles predictores de la flexibilidad cognitiva y la autoeficacia en el bienestar mental de los adolescentes turcos. Además, dado que se considera que la asociación entre la flexibilidad cognitiva y la autoeficacia tiene efectos cruciales en el bienestar mental de los adolescentes, se suponía que la autoeficacia académica, social y emocional podría mediar la relación entre la flexibilidad cognitiva y el bienestar mental. Los participantes de la investigación están compuestos por 192 mujeres (49 %) y 200 hombres (51 %), Un total de 392 estudiantes de secundaria que asistían a cuatro escuelas secundarias diferentes se inscribieron en los grados 9-12, en una ciudad de Turquía. El Inventario de Flexibilidad Cognitiva, la Escala de Autoeficacia para Niños y la Escala de Bienestar Mental Warwick-Edinburgh se aplicaron en la recolección de datos. Los resultados mostraron que la flexibilidad cognitiva se correlacionó positivamente con las subdimensiones de autoeficacia y bienestar mental. Además, las subdimensiones de autoeficacia se correlacionan positivamente con el bienestar mental. Los resultados del modelo mediacional indicaron que la autoeficacia académica, social y emocional sirvió para mediar la relación entre la flexibilidad cognitiva y el bienestar mental. Los resultados de la investigación se discutieron a la luz de la literatura y se propusieron algunas sugerencias para expertos e investigadores en salud mental. El Inventario de Flexibilidad Cognitiva, la Escala de Autoeficacia para Niños y la Escala de Bienestar Mental Warwick-Edinburgh se aplicaron en la recolección de datos. Los resultados mostraron que la flexibilidad cognitiva se correlacionó positivamente con las subdimensiones de autoeficacia y bienestar mental. Además, las subdimensiones de autoeficacia se correlacionan positivamente con el bienestar mental. Los resultados del modelo mediacional indicaron que la autoeficacia académica, social y emocional sirvió para mediar la relación entre la flexibilidad cognitiva y el bienestar mental. Los resultados de la investigación se discutieron a la luz de la literatura y se propusieron algunas sugerencias para expertos e investigadores en salud mental


Assuntos
Humanos , Masculino , Feminino , Adolescente , Cognição/fisiologia , Autoeficácia , Psicologia do Adolescente , Estudantes/psicologia , Turquia , Saúde Mental , Ensino Fundamental e Médio , Ajustamento Social , Projetos de Pesquisa , Estudantes/estatística & dados numéricos , Inquéritos e Questionários
5.
Allergol. immunopatol ; 47(6): 558-563, nov.-dic. 2019. graf, tab
Artigo em Inglês | IBECS | ID: ibc-186548

RESUMO

Introduction and objectives: Food allergy in school children ranges between 5.7 and 6.4% in Turkey. Studies emphasize the importance of improving school personnel's self-efficacy in managing food allergy and anaphylaxis. However, a brief and valid measurement tool for school personnel is not available in Turkey. The aim of this study was to determine the validity and reliability of the Turkish version of the School Personnel's Self-efficacy in Managing Food Allergy and Anaphylaxis (SPSMFAA-T) scale with teachers. Patients or materials and methods: This methodological study was conducted by 282 primary school teachers. Data were collected with a demographic characteristics form and SPSMFAA-T. The psychometric properties of the SPSMFAA-T were evaluated by content, discriminant, construct validity and internal consistency. Results: Cronbach's alpha for the scale was 0.91 and item-total correlations were between 0.50 and 0.82 (p < 0.001). The discriminant validity suggested that the scale successfully discriminated the teachers who had training on food allergy and anaphylaxis from the teachers who did not. The model fit indices of scale were determined to be the root mean square error of approximation (RMSEA) at 0.08, goodness of fit index (GFI) at 0.96, comparative fit index (CFI) at 0.99. Conclusions: The results supported that the SPSMFAA-T was a valid and reliable measurement tool to assess Turkish teachers’ self-efficacy levels to manage food allergy and anaphylaxis in school setting. The scale can be used in education programs to improve school personnel's skills to manage food allergy and anaphylaxis


No disponible


Assuntos
Humanos , Feminino , Adulto , Pessoa de Meia-Idade , Autoeficácia , Hipersensibilidade Alimentar/diagnóstico , Anafilaxia/terapia , Psicometria/métodos , Docentes/estatística & dados numéricos , Hipersensibilidade Alimentar/terapia , Psicometria/instrumentação , Turquia , Análise Fatorial , Análise de Regressão
6.
Rev. esp. quimioter ; 32(6): 516-524, dic. 2019. tab
Artigo em Inglês | IBECS | ID: ibc-190610

RESUMO

OBJECTIVES: The aim of this study was to determine the human papillomavirus (HPV) genotype distribution and to investigate the relationship between HPV genotypes and cervical cytology in women with HPV infection. MATERIAL AND METHODS: In this study, 493 women who were admitted to the obstetrics clinic between 2007 and 2015 years and had HPV positivity were examined retrospectively. RESULTS: The median age of women included in the study was 37.3 +/-10.6. The positivity of single and multiple HPV genotypes was 64.1% and 35.9%, respectively. HPV16 was the most common genotype in women with normal and abnormal cytology. The incidence of atypical squamous cells of undetermined significance (chi-square:8.32 p = 0.04) and high-grade squamous intraepithelial lesion (chi-square:13.75 p < 0.001) with HPV16 was significantly higher than in other HPV genotypes. In additional, abnormal cytology results in the group 1 (included HPV16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59) and group 4 (included HPV40, 42, 54, 55, 61, 62, 81, 83, 84) were significantly higher than other groups (chi-square:23.15 p < 0.001). CONCLUSIONS: Group 1 genotype ratios were found to be quite high among women with abnormal cytology and women with normal cytology. For this reason, close follow-up is very important in addition to cytological findings along with genotyping, especially from an early age. We were found that multiple HPV infection was not related to the grades of cytological abnormalities. Although abnormal cytology results in group 4 were significantly higher than the other groups, it was not possible to comment on the relationship between these genotypes and cervical cancer since more than one HPV genotype was found in most of these women


OBJETIVOS: El objetivo de este estudio fue determinar la distribución del genotipo del virus del papiloma humano (VPH) e investigar la relación entre los genotipos del VPH y la citología cervical en mujeres con infección por VPH. MATERIAL Y MÉTODOS: En este estudio, 493 mujeres que ingresaron en la clínica de obstetricia entre los años 2007 y 2015, y que presentaron VPH positivo fueron examinadas retrospectivamente. RESULTADOS: La edad media de las mujeres incluidas en el estudio fue de 37,3 +/- 10,6. La positividad de los genotipos de VPH individuales y múltiples fue de 64,1% y 35,9%, respectivamente. VPH16 fue el genotipo más común en mujeres con citología normal y anormal. La incidencia de células escamosas atípicas de importancia indeterminada (chi-cuadrado: 8,32 p: 0,04) y lesión intraepitelial escamosa de alto grado (chi-cuadrado: 13,75 p <0,001) con VPH16 fue significativamente mayor que en otros genotipos de VPH. Además, los resultados citológicos anormales en el grupo 1 (incluido VPH 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59) y el grupo 4 (incluido el VPH 40, 42, 54, 55, 61, 62, 81, 83, 84) fueron significativamente más altos que en otros grupos (chi-cuadrado: 23,15 p <0,001). CONCLUSIONES: Se encontró que las proporciones de genotipos del grupo 1 fueron bastante altas entre las mujeres con citología anormal y las mujeres con citología normal. Por esta razón, el seguimiento cercano es muy importante además de los hallazgos citológicos junto con el genotipado, especialmente desde una edad temprana. Se encontró que la infección múltiple por VPH no estaba relacionada con los grados de anomalías citológicas. Aunque los resultados anormales de la citología en el grupo 4 fueron significativamente superiores a los otros grupos, no fue posible valorar la relación estos genotipos y el cáncer cervical ya que se encontró más de un genotipo de VPH en la mayoría de estas mujeres


Assuntos
Humanos , Feminino , Adulto Jovem , Adulto , Pessoa de Meia-Idade , Idoso , Colo do Útero/patologia , Colo do Útero/virologia , Papillomaviridae/genética , Infecções por Papillomavirus/virologia , Genótipo , Papillomaviridae/isolamento & purificação , Estudos Retrospectivos , Turquia , Esfregaço Vaginal
7.
Acta otorrinolaringol. esp ; 70(5): 286-289, sept.-oct. 2019. tab
Artigo em Inglês | IBECS | ID: ibc-186372

RESUMO

Introduction: Pediatric epistaxis is very common. A child's illness can lead to depression and anxiety in the parents. The association between pediatric epistaxis and mothers’ anxiety has not been well documented. Objective: The present study is aimed at measuring depression and anxiety levels in mothers of children with mild, recurrent epistaxis. Methods: This prospective, clinical, questionnaire-based study examined 43 mothers of children with recurrent epistaxis and 42 mothers of healthy children. The depression and anxiety levels of the mothers in both the groups were assessed with the Beck Depression Inventory (BDI), the state-trait anxiety inventory-state (STAI-S), and the state-trait anxiety inventory-trait (STAI-T). Results: No statistically-significant differences were found between the two groups of mothers in terms of educational level, employment, age, or economic status. The mean STAI-S scores were higher in the mothers of children with epistaxis (p = .010). However, no statistically-significant differences were found between the two groups for the BDI and STAI-T scores. Conclusions: The results of this comparative study suggest that mild, recurrent epistaxis in children can significantly increase their mothers' state anxiety levels, but epistaxis has no significant effect on either depression or trait anxiety


Introducción: La epistaxis pediátrica es muy común. La enfermedad de un niño puede provocar depresión y ansiedad en los padres. La asociación entre la epistaxis pediátrica y la ansiedad de las madres no ha sido bien documentada. Objetivo: El presente estudio tuvo como objetivo medir los niveles de depresión y ansiedad en madres de niños con epistaxis recurrente leve. Métodos: Este estudio prospectivo, clínico y basado en cuestionarios, examinó a 43 madres de niños con epistaxis recurrente y 42 madres de niños sanos. Los niveles de depresión y ansiedad de las madres en ambos grupos se evaluaron con el Inventario de Depresión de Beck (BDI), el estado de inventario de ansiedad con rasgo de estado (STAI-S) y el rasgo de inventario de ansiedad con rasgo de estado (STAI-T). Resultados: No se encontraron diferencias estadísticamente significativas entre los 2 grupos de madres en términos de nivel educativo, empleo, edad o estado económico. Las puntuaciones promedio de STAI-S fueron más altas en las madres de niños con epistaxis (p = 0,010). Sin embargo, no se encontraron diferencias estadísticamente significativas entre los 2 grupos para las puntuaciones BDI y STAI-T. Conclusiones: Los resultados de este estudio comparativo sugieren que la epistaxis leve y recurrente en los niños puede aumentar significativamente los niveles de ansiedad del estado de sus madres, pero la epistaxis no tiene un efecto significativo sobre la depresión o la ansiedad


Assuntos
Humanos , Pré-Escolar , Criança , Adolescente , Adulto Jovem , Adulto , Pessoa de Meia-Idade , Ansiedade/etiologia , Depressão/etiologia , Epistaxe , Mães/psicologia , Relações Mãe-Filho , Estudos Prospectivos , Testes Psicológicos , Recidiva , Estresse Psicológico/etiologia , Inquéritos e Questionários , Turquia
8.
An. psicol ; 35(3): 521-528, oct. 2019. tab, graf
Artigo em Inglês | IBECS | ID: ibc-190041

RESUMO

The aim of this study was to investigate a mediator role of cynicism in the relationship between burnout and wellbeing. Participants were 326 teacher candidates [189 (58%) female, 137 (42%) male, Mage = 23.14 years, SD = 2.36]  who completed questionnaires package the Burnout Measure Short Version, the Positive and Negative Affect Schedule, Life with Satisfaction Scale and the Hunter Cynicism Scale. The data were analyzed using structural equation modeling. A bootstrapping analysis was conducted in order to determine any indirect effects. The results showed that burnout predicted cynicism positively and wellbeing negatively, and that cynicism predicted wellbeing negatively. It was further found that the structural equation model that proposed that burnout had a direct and an indirect effect through cynicism on wellbeing was confirmed. The results of the study were discussed in the light of relevant literature, and suggestions for future studies were made


El objetivo de este estudio fue investigar el papel mediador del cinismo en la relación entre el agotamiento y el bienestar. Los participantes fueron 326 maestros candidatos [189 (58%) mujeres, 137 (42%) hombres, Medad= 23.14 años, DT= 2.36] que completaron los cuestionarios el grupo de Burnout Measure Short Version, Positive and Negative Affect Schedule, Life with Satisfaction Scale y el Hunter Cynicism Scale. Los datos fueron analizados utilizando modelos de ecuaciones estructurales. Se realizó un análisis de arranque para determinar los efectos indirectos. Los resultados mostraron que el agotamiento predijo el cinismo de manera positiva y el bienestar de manera negativa, y que el cinismo predijo el bienestar de manera negativa. Se encontró además que se confirmó el modelo de ecuación estructural que proponía que el agotamiento tenía un efecto directo e indirecto a través del cinismo sobre el bienestar. Los resultados del estudio se discutieron a la luz de la literatura relevante, y se hicieron sugerencias para futuros estudios


Assuntos
Humanos , Masculino , Feminino , Adulto , Esgotamento Profissional/psicologia , Condições de Trabalho , Motivação , Docentes/estatística & dados numéricos , Docentes/psicologia , Inventário de Personalidade/estatística & dados numéricos , Inquéritos e Questionários , Turquia , Satisfação Pessoal
9.
Allergol. immunopatol ; 47(3): 254-259, mayo-jun. 2019. tab
Artigo em Inglês | IBECS | ID: ibc-186486

RESUMO

Background: Quality of life, which is impaired in patients with chronic spontaneous urticaria (CSU), is influenced by comorbid mental disorders. Headaches could be another comorbid mental disorder that affects quality of life in children with CSU. Objectives: To investigate the effect of headaches on urticaria symptoms, disease activity and quality of life in children with CSU. Methods: A total of 83 patients with CSU were enrolled in the study and were separated into two groups as those with or without headache. Demographic and clinical characteristics were studied with the Urticaria Activity Score (UAS7), Urticaria Control test (UCT) and Chronic Urticaria Quality of Life Questionnaire (CU-Q2QoL). The headache questionnaire designed according to the Department of International Classification of Headache Disorders, second edition (ICHD-II) was used and VAS (Visual Analogue Scale) and NRS (Numerical Rating Scale) were used to assess the pain measurement. In patients diagnosed with migraine, the paediatric Migraine Disability Assessment Scale (PedMIDAS) was applied. Results: CU-QoL total scores were significantly higher in patients with CSU with headache than in those without headache (p = 0.015). In the five domains of CU-QoL, impact of daily life activities domain and sleep problems domain had higher scores in CSU with headache (p = 0.008, 0.028, respectively). There was no significant relationship between UCT, UAS and CU-QoL and headache severity (p < 0.05). No differences were found between the groups in respect of duration of urticaria, UAS7 and UCT. Conclusion: Headache may be an important factor that affects and impairs quality of life in children with chronic urticarial


No disponible


Assuntos
Humanos , Masculino , Feminino , Criança , Adolescente , Cefaleia/fisiopatologia , Urticária/fisiopatologia , Doença Crônica , Estudos Transversais , Cefaleia/epidemiologia , Medição da Dor , Qualidade de Vida , Índice de Gravidade de Doença , Inquéritos e Questionários , Turquia/epidemiologia , Urticária/epidemiologia
10.
Endocrinol. diabetes nutr. (Ed. impr.) ; 66(2): 90-98, feb. 2019. tab
Artigo em Inglês | IBECS | ID: ibc-175800

RESUMO

Introduction: Increasing number of experimental and clinical studies suggest a strong relationship between hyperglycemia, oxidative stress, DNA damage and diabetic nephropathy (DN). Also, epidemiologic studies remark an enhanced risk of cancer with type 2 diabetes. This research aims to assess whether the X-ray cross complementing group 3 (XRCC3) gene T241M polymorphism (rs861539) and X-ray cross complementing group 1 (XRCC1) gene A399G polymorphism (rs25487) are related with predisposition to type 2 diabetes mellitus (T2DM) and to diabetic nephropathy in Turkish population. Materials and methods: Polymerase chain reaction-based restriction fragment length polymorphism (PCR-RFLP) was performed to identify the distribution of genotypes and frequency of alleles of T241M polymorphism of the XRCC3 gene (XRCC3 T241M) and A399G polymorphism of the XRCC1 gene (XRCC1 A399G). The study population included 238 subjects residing in Istanbul, Turkey; 116 with T2DM, 50 with DN and 72 with normal glucose metabolism. Results and conclusion: Polymorphic Gln allele of XRCC1 gene was significantly related with T2DM and DN (OR 3.09, 95% CI 1.14-8.40 and OR 3.29 95% CI 1.23-8.80, respectively) however, there was no statistical association of XRCC3 T241M with T2DM or DN. The results of this study suggest that XRCC1 399Gln polymorphism is related with an increased susceptibility to T2DM and DN in the studied Turkish population


Introducción: Un número creciente de estudios experimentales y clínicos sugiere una sólida relación entre hiperglucemia, estrés oxidativo, daño en el ADN y nefropatía diabética (ND). Además, los estudios epidemiológicos advierten mayor riesgo de cáncer con diabetes de tipo 2. Esta investigación tiene como objetivo evaluar si el polimorfismo del gen T241M del grupo 3 (XRCC3) complementario cruzado de rayos X (rs861539) y el polimorfismo del gen A399G del grupo 1 (XRCC1) complementario cruzado de rayos X (rs25487) están relacionados con la predisposición a la diabetes mellitus de tipo 2 (DM2) y a la nefropatía diabética en la población turca. Materiales y métodos: Se realizó un polimorfismo de longitud de fragmento de restricción basado en la reacción en cadena de la polimerasa (PCR-RFLP) para identificar la distribución de genotipos y la frecuencia de los alelos del polimorfismo T241M del gen XRCC3 (XRCC3 T241M) y el polimorfismo A399G del gen XRCC1(XRCC1 A399G). La población de estudio incluyó a 238 individuos que residían en Estambul, Turquía; 116 de ellos con DM2, 50 con ND y 72 con metabolismo de la glucosa normal. Resultados y conclusión: El alelo Gln polimórfico del gen XRCC1 se relacionó de manera importante con DM2 y ND (OR: 3,09; IC95%: 1,14-8,40 y OR: 3,29; IC95%:1,23-8,80, respectivamente). Sin embargo, no hubo asociación estadística de XRCC3 T241M con DM2 o ND. Los resultados de este estudio sugieren que el polimorfismo XRCC1 399Gln está relacionado con un aumento de la susceptibilidad a la DM2 y a la ND en la población turca estudiada


Assuntos
Humanos , Masculino , Feminino , Adulto Jovem , Adulto , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Diabetes Mellitus Tipo 2/genética , Neuropatias Diabéticas/genética , Reparo do DNA/fisiologia , Polimorfismo de Fragmento de Restrição/genética , Polimorfismo Genético/genética , Polimorfismo Genético/fisiologia , Turquia , Polimorfismo de Fragmento de Restrição/fisiologia , Diabetes Mellitus Tipo 2/diagnóstico , Nefropatias Diabéticas/diagnóstico
11.
Rev. esp. salud pública ; 93: 0-0, 2019. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-189554

RESUMO

OBJETIVO: En la literatura científica no están claros los impactos de la plaquetoféresis sobre los parámetros del leucograma, y existe una gran divergencia en los estudios que han evaluado el recuento de leucocitos. El objetivo de este estudio fue metanalizar el efecto de la plaquetoféresis sobre el recuento de leucocitos, con base en estudios publicados entre 1980-2018. MÉTODOS: Se realizó una revisión sistemática con metaanálisis de efectos aleatorios para la diferencia de medias. Se aplicaron las fases de la guía PRISMA, con 132 estrategias de búsqueda en Pubmed, Scielo, Science Direct y Scopus. Se garantizó la reproducibilidad y evaluación de la calidad metodológica. Se evaluó la heterogeneidad con Galbraith y Dersimonian y Laird's, el sesgo de publicación con Funnel Plot y Begg, y se realizaron análisis de sensibilidad, metaanálisis acumulado y Forest Plot. RESULTADOS: Se incluyeron 19 estudios con 2.358 donantes, la mayoría de India, Estados Unidos, Turquía, Alemania y Austria. Se halló una diferencia de medias de -0,80 x109⁄L (IC95%= -1,96; 0,36x109⁄L) entre el valor pre donación y el valor inmediatamente posterior a la donación. No se encontró sesgo de publicación en los estudios y la medida combinada presentó buena sensibilidad, dado que no varió con la eliminación de estudios específicos. CONCLUSIONES: La donación de plaquetas por aféresis no afecta al recuento de leucocitos en los donantes. En el siglo pasado, se reportaban reducciones en este parámetro, explicadas por la pérdida de sangre en los estuches utilizados para el procedimiento y debido a los efectos producidos en las células sanguíneas por los biomateriales de los estuches. Sin embargo, en la actualidad se evidencia la alta seguridad de la plaquetoféresis para el recuento de glóbulos blancos


BACKGROUND: In the scientific literature, the impacts of plateletpheresis on leukogram parameters are not clear, with a high divergence in the studies that have evaluated changes in leukocytes. The objective of this paper was to meta-analyze the effect of plateletpheresis on the leukocyte count, based on studies published between 1980-2018. METHODS: Systematic review with meta-analysis of random effects for the difference of means. The phases of the PRISMA guide were applied with 132 search strategies in Pubmed, Scielo, Science direct and Scopus. Reproducibility and evaluation of methodological quality were guaranteed. Heterogeneity was evaluated with Galbraith and Dersimonian and Laird's, publication bias with Funnel Plot and Begg; sensitivity analysis, accumulated meta-analysis and Forest Plot were carried out. RESULTS: Nineteen studies were included with 2,358 donors, mostly from India, United States, Turkey, Germany and Austria. A mean difference of -0,80 x109⁄L (IC95%= -1,96; 0,36x109⁄L) between the predonation value and the value immediately after donation was founded; no publication bias was found and the conclusion presented good sensitivity since it does not vary with the elimination of studies in successive phases. CONCLUSIONS: The donation of platelets by apheresis does not affect the leukocyte count in the donors, in the last century there were reports of reductions in this parameter, explained by the blood loss in the cases used for the procedure and by effects produced in the blood cells by the biomaterials; however, at present the high safety of plateletpheresis for the white blood cell count is evidenced


Assuntos
Humanos , Contagem de Células Sanguíneas , Leucócitos/citologia , Contagem de Plaquetas , Plaquetoferese/métodos , Áustria , Materiais Biocompatíveis , Índia , Reprodutibilidade dos Testes , Turquia , Estados Unidos , Doadores de Sangue , Alemanha
13.
Allergol. immunopatol ; 46(6): 546-551, nov.-dic. 2018. tab
Artigo em Inglês | IBECS | ID: ibc-177893

RESUMO

Introduction and objectives: Atopic dermatitis (AD) is a chronic inflammatory disease of the skin. Apart from its well-known role on calcium metabolism, vitamin D is reported to affect skin functions. The study aims were to: compare the vitamin D levels of children with AD and healthy children; investigate the relationship between the severity of AD and vitamin D levels; and investigate the effect of vitamin D on the natural course of AD. Patients or materials and methods: Sixty-nine patients with AD were enrolled. Seventy healthy children were assigned as control group. Clinical and demographic features of groups were recorded. The skin prick test, eosinophil counts, immunoglobulin (Ig) E levels and serum 25 OH cholecalciferol (25OHD3) levels were measured. After at least 4 years of follow-up, patients were re-evaluated for natural course of AD. Results: Mean 25OHD3 level was lower in patient group vs. control group; 19.86 ± 6.7 ng/mL (min-max: 6.8-40) vs. 24.07 ± 9.08 ng/mL, respectively, (p = 0.002). Mean 25OHD3 levels, and vitamin D status were significantly different between AD severity groups. (p < 0.05). In terms of vitamin D status in the pairwise comparison, vitamin D deficiency was greater in children with severe and moderate AD groups (respectively, p = 0.005, p = 0.018). In Tukey's post hoc analysis for 25OHD3 level, the 25OHD3 levels of severe AD are significantly lower than mild or moderate AD (respectively, p = 0.001, p = 0.026). There was a negative correlation between 25OHD3 levels and severity of AD (r = -0.480; p =0.001). In patients reassessed after 4 years: age, the age of AD onset, vitamin D deficiency, SCORAD level and severe AD were higher in the persistent group vs. remission group, 25OHD3 levels were higher in the remission group vs. persistent group (p < 0.05). Conclusions: Mean vitamin D levels were lower in patients with AD. A negative correlation between vitamin D levels and disease severity was documented. Vitamin D may affect the natural course of atopic dermatitis. There is a need for more comprehensive studies in this regard


No disponible


Assuntos
Humanos , Masculino , Feminino , Pré-Escolar , Criança , Dermatite Atópica/epidemiologia , Vitamina D/sangue , Deficiência de Vitamina D/epidemiologia , Progressão da Doença , Índice de Gravidade de Doença , Testes Cutâneos , Turquia/epidemiologia
14.
Allergol. immunopatol ; 46(6): 571-577, nov.-dic. 2018. tab, graf
Artigo em Inglês | IBECS | ID: ibc-177897

RESUMO

Introduction and objectives: Atopic dermatitis (AD) is an eczematous skin disease. Our aim was to evaluate the clinical and laboratory findings of children with AD and identify the higher responsive group to moisturizers. Materials and methods: Total and specific IgE, eosinophil count, prick/patch test results of patients with AD were retrospectively analyzed. The presentation SCORAD was compared between the demographic and clinical subgroups. The SCORAD change (presentation to third month) between the intrinsic and extrinsic groups was compared. The effect of age, sex, disease duration, presentation SCORAD, being intrinsic/extrinsic, exclusive breastfeeding duration, familial atopy, total IgE, eosinophil count, concomitant illness presence, moisturizer use frequency and exacerbation frequency on SCORAD change was examined. Results: The mean age was 3.65 ± 3.77 years. Food allergy was found in 5.90% and inhalant allergy was found in 12.67% of patients. 158 (44.5%) were mild, 154 (43.4%) were moderate and 43 (12.1%) were severe AD. 141 (39.7%) were intrinsic AD. The SCORAD at 3rd visit and SCORAD change was different between the intrinsic and extrinsic groups. SCORAD change was positively associated with presentation SCORAD, eosinophil count, moisturizer use frequency and being extrinsic AD. Conclusions: The clinical and laboratory findings of AD patients in our community were revealed. Higher SCORAD and eosinophils at presentation, frequent daily moisturizer use and being extrinsic increased the moisturizer response. Although the barrier defect was shown to be lesser in intrinsic AD by considering transepidermal water loss, this study is the first to evaluate intrinsic and extrinsic AD patients according to response to moisturizers


No disponible


Assuntos
Humanos , Masculino , Feminino , Recém-Nascido , Lactente , Pré-Escolar , Criança , Dermatite Atópica/epidemiologia , Emolientes/uso terapêutico , Eosinófilos/patologia , Pele/patologia , Dermatite Atópica/terapia , Progressão da Doença , Imunoglobulina E/sangue , Estudos Retrospectivos , Fenótipo , Índice de Gravidade de Doença , Testes Cutâneos , Turquia/epidemiologia
15.
Eur. j. psychol. appl. legal context (Internet) ; 10(2): 65-78, jul.-dic. 2018. tab, graf
Artigo em Inglês | IBECS | ID: ibc-174093

RESUMO

We systematically linked cross-cultural literature to the Central Eight risk factors as an example of risk assessment procedures. We expected offenders with a migration background (MB) from Turkey or Arab countries to score higher on criminal history, criminal attitudes, antisocial companions, and education and employment problems in comparison to German offenders without an MB. In contrast, for offenders with an MB from Turkey or Arab countries, a reduced risk for unsatisfactory relationships with their parents, alcohol, and leisure-related factors was assumed. The Central Eight risk factors were applied retrospectively for male offenders serving a sentence length of more than 12 months. German offenders without an MB (n = 214) were compared to offenders with a Turkish (n = 135) or Arab (n = 112) MB concerning risk profiles and predictive validity. Risk profiles of offenders with an MB deviated (d = 0.25-0.56) from risk profiles of German offenders without an MB. For offenders without an MB criminal history, antisocial personality, criminal attitudes, antisocial companions, and alcohol/drug problems significantly predicted (AUC = .56-.73) different recidivism events. Similar results were found for offenders with a Turkish MB (AUC = .60-.70) except for antisocial companions (AUC = .50). Results for offenders with an Arab MB were inconclusive; only alcohol/drug problems consistently showed good predictive values (AUC = .66-.68). Findings demonstrate that a culture-sensitive approach in risk assessment is inevitable and recommendations for culture-sensitive research, risk assessment, and offender treatment are discussed


Se ha relacionado sistemáticamente la literatura multicultural con los ocho factores centrales de riesgo, como ejemplo de procesos de evaluación de riesgo. Se esperaba que los delincuentes con origen migratorio (OM) en Turquía o en países árabes obtuviesen una puntuación más alta en historial y actitud delictivos, relaciones interpersonales antisociales y problemas de educación y empleo, en comparación con los delincuentes alemanes sin origen migratorio (OM). En contraste, se asumía que los delincuentes con origen migratorio en Turquía y países árabes tenian menor riesgo de relaciones insatisfactorias con sus padres, alcohol y factores relacionados con el ocio. Se utilizaron retrospectivamente los ocho factores centrales de riesgo con delincuentes masculinos condenados a más de 12 meses. Se compararon delincuentes alemanes sin origen migratorio (n = 214) y delincuentes con origen migratorio en Turquía (n = 135) o en países árabes (n = 112) con respecto a perfiles de riesgo y validez predictiva. Los perfiles de riesgo de los delincuentes con OM se desviaban (d = 0.25, 0.56) de los perfiles de riesgo de los alemanes sin OM. Para delincuentes sin OM de historial delictivo, personalidad antisocial, actitud delictiva, relaciones antisociales y problemas de alcoholismo y drogadicción se predijeron (AUC = .56-.73) diferentes episodios de reincidencia. Se obtuvieron resultados similares para delincuentes turcos con OM (AUC = .60-.70), excepto en relaciones antisociales (AUC = .50). Los resultados para los delincuentes árabes con OM fueron inconcluyentes; solo los problemas de alcoholismo y drogadicción mostraron invariablemente valores predictivos fidedignos (AUC = .66-68). Los resultados demuestran que es inevitable un acercamiento sensible a la cultura en la evaluación del riesgo. Se dan recomendaciones para una investigación sensible a la cultura, la evaluación del riesgo y el tratamiento de los delincuentes


Assuntos
Humanos , Masculino , Adulto Jovem , Adulto , Pessoa de Meia-Idade , Idoso , Crime/estatística & dados numéricos , Transtornos Relacionados ao Uso de Substâncias/epidemiologia , Transtornos Relacionados ao Uso de Álcool/epidemiologia , Fatores de Risco , Causalidade , Fatores Culturais , Comparação Transcultural , Migração Humana/estatística & dados numéricos , Emigrantes e Imigrantes/estatística & dados numéricos , Arábia/epidemiologia , Turquia/epidemiologia , Prisões/estatística & dados numéricos
16.
Endocrinol. diabetes nutr. (Ed. impr.) ; 65(7): 409-417, ago.-sept. 2018. tab
Artigo em Inglês | IBECS | ID: ibc-176127

RESUMO

Background: A long-term diabetic complication, fatigue, which is a direct result of treatment and psychological processes, is a common symptom in diabetic individuals. Aims: To determine the reliability and validity of Functional Assessment of Chronic Illness Treatment-Fatigue Scale in Turkish patients with type 2 diabetes. Study design: A methodological study. Methods: The sample consisted of 133 patients with type 2 diabetes who agreed to participate in the study and met the criteria for the study. Data were collected using the descriptive information form prepared by the researcher and the Scale obtained from FACIT System. The research data were collected by face-to-face interviews with the patients. Language and content validity of the Turkish version of the Scale was provided, Cronbach's Alpha coefficient, test-retest analysis and item analysis methods were used as reliability analysis. Results: The total Cronbach Alpha coefficient of the scale was found to be 0.92. According to the results of factor analysis, unlike the original scale, two sub-dimensions emerged in the Turkish version of the scale. Conclusions: As a result of the validity and reliability analysis of the FACIT-Fatigue Scale, it can be said that it provides psychometric measures that can be used to determine the level of fatigue of type 2 diabetes patients in Turkish society


Antecedentes: La fatiga, una complicación a largo plazo de la diabetes que es consecuencia directa del tratamiento y de procesos psicológicos, es un síntoma frecuente en los diabéticos. Objetivos: Determinar la fiabilidad y la validez de la escala de fatiga de la valoración funcional del tratamiento de enfermedades crónicas (FACIT) en pacientes turcos con diabetes tipo 2. Diseño del estudio: Estudio metodológico. Métodos: La muestra constaba de 133 pacientes con diabetes tipo 2 que aceptaron participar y cumplían los criterios del estudio. Se recogieron datos mediante el impreso informativo descriptivo preparado por el investigador y la escala obtenida del sistema FACIT. Los datos se recogieron en entrevistas personales con los pacientes. Se informa de la validez del idioma y el contenido de la versión turca de la escala, y se utilizaron el coeficiente alfa de Cronbach, el análisis prueba-reprueba y métodos de análisis de ítems para analizar la fiabilidad. Resultados: El coeficiente alfa total de Cronbach de la escala era 0,92. Según los resultados del análisis de factores, a diferencia de la escala original, en la versión turca de la escala surgieron 2 subdimensiones. Conclusiones: Basándose en el resultado de los análisis de validez y fiabilidad de la escala de fatiga de la FACIT, puede afirmarse que proporciona medidas psicométricas que pueden emplearse para determinar el grado de fatiga de los pacientes con diabetes tipo 2 en la sociedad turca


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Fadiga , Doença Crônica/tratamento farmacológico , Pesos e Medidas , Reprodutibilidade dos Testes , Diabetes Mellitus Tipo 2/complicações , Turquia , Inquéritos e Questionários , Reprodutibilidade dos Testes/métodos
17.
Clin. transl. oncol. (Print) ; 20(5): 606-612, mayo 2018. tab, graf
Artigo em Inglês | IBECS | ID: ibc-173537

RESUMO

Background. Plantar surface melanoma affects the Caucasian race less likely than it does other races, e.g., the Asians and the Blacks. So far, small numbers of researches on plantar melanoma have yielded controversial results. The aim of this study was to define the histopathological and clinical characteristics pertinent to plantar melanoma and to compare them with melanomas that emerged in other sites by using a large group of patients from a single institution. Patients and methods. A total of 104 Turkish Caucasian plantar melanoma patients and 1065 patients with non-plantar melanomas were analyzed retrospectively. Results. The plantar melanomas were found more frequently in females (p = 0.006) and in older patients (≥ 50 years old) (p = 0.002). Compared to melanomas in other sites, the plantar melanomas tended to have more acral lentiginous histopathology (p = 0.0001), deeper Clark invasion level (IV-V) (p = 0.01), and thicker Breslow depth (≥ 2 mm) (p = 0.05); and the plantar melanoma lesions were more likely ulcerated (p = 0.0001) and were correlated with more lymphovascular invasion (p = 0.001), fewer tumor infiltrating lymphocyte (p = 0.03), and less frequently associated with a preexisting melanocytic nevus (p = 0.01). However, no correlation was found between plantar localization and either nodal involvement or metastasis (p > 0.05). The recurrence free and overall survival times for plantar melanomas were similar to other sites (p > 0.05). 5-year overall survival rate in plantar melanoma patients were 59%. Conclusion. Even though plantar melanoma is associated with certain poor histopathological factors, it is not correlated with nodal involvement, recurrence, and poor survival


No disponible


Assuntos
Humanos , Masculino , Feminino , Adolescente , Adulto Jovem , Adulto , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Melanoma/mortalidade , Melanoma/patologia , Neoplasias Cutâneas/patologia , Neoplasias Cutâneas/epidemiologia , Intervalo Livre de Doença , Pé/patologia , Estimativa de Kaplan-Meier , Metástase Linfática/patologia , Recidiva Local de Neoplasia/patologia , Prognóstico , Estudos Retrospectivos , Neoplasias Cutâneas/mortalidade , Turquia/epidemiologia
18.
Arch. esp. urol. (Ed. impr.) ; 71(1): 18-22, ene.-feb. 2018. tab
Artigo em Inglês | IBECS | ID: ibc-171823

RESUMO

Objective: Urology residency training is a difficult and complex education period for urology residents. This education period differs in countries and mainly for 5 years. In this study, we aimed to assess the expectations and the realities for Turkish urology residents and to evaluate the adequacy of their education in the field of urology. Methods: In this study, 113 Turkish urology residents have been included and residents were asked 24 questions related with their surgical skills, thoughts towards their educations, their future plans and including demographic information. Results: The years of residency were divided as; 1st year-12 (10.6%), 2nd year-17 (15%), 3rd year-22 (19.4%), 4th year-24 (21.3%) and 5th year-38 (33.7%). Mainly they suffered from the lack of practical education and the lack of encouragement to scientific and academic works, studies. Conclusion: Urological education must be standardized and must cover the educational needs of urology residents (AU)


Objetivo: La formación en residencia de urología es un período de educación dificil y complejo para los residentes de urología. Este período de educación difiere en los países y principalmente durante 5 años. En este estudio, nuestro objetivo era evaluar las expectativas y las realidades para los residentes urológicos turcos y evaluar la adecuación de su educación en el campo de la urología. Métodos: En este estudio, se incluyeron 113 residentes de urología turcos y se les hizo a los residentes 24 preguntas relacionadas con sus habilidades quirúrgicas, pensamientos hacia sus estudios, sus planes futuros e incluyendo información demográfica. Resultados: El año de residencia se dividió como; 1er año -12 (10,6%), 2º año-17 (15%), 3er año-22 (19,4%), 4º año-24 (21,3%) y 5º año-38 (33,7%). Principalmente sufrían por la falta de educación práctica y la falta de estímulo a los trabajos científicos y académicos, a los estudios. Conclusion: La educación urológica debe estar estandarizada y debe cubrir las necesidades educativas de los residentes de urología (AU)


Assuntos
Humanos , Masculino , Feminino , Adulto , Urologia/educação , Internato e Residência/tendências , Turquia , Procedimentos Cirúrgicos Urológicos/educação , 34600
19.
Allergol. immunopatol ; 45(5): 445-451, sept.-oct. 2017. tab, graf
Artigo em Inglês | IBECS | ID: ibc-166998

RESUMO

Background: The diagnostic values for the skin prick test (SPT) diameters and egg white-specific IgE (EW-sIgE) levels that will allow us to predict the result of the oral food challenge test (OFC) in the diagnosis of egg white allergy vary by the community where the study is carried out. Objective: This study aimed to determine the diagnostic values of SPT and EW-sIgE levels in the diagnosis of egg white allergy. Methods: 59 patients followed with the diagnosis of egg allergy September 2013 to September 2015 were included in our retrospective cross-sectional study. The patients were investigated in terms of egg and anaphylaxis history or the requirement of the OFC positivity. The demographic, clinical and laboratory findings of the cases were recorded, and they were compared with the patients with the suspected egg allergy but negative OFC (n = 47). Results: In the study, for all age groups, the value of 5mm in SPT was found to be significant at 96.4% positive predictive value (PPV) and 97.8% specificity and the value of 5.27kU/L for EW-sIgE was found to be significant at 76% PPV and 86.6% specificity for egg white. The diagnostic power of the SPT for egg white (AUC: 72.2%) was determined to be significantly higher compared to the diagnostic power of the EW-sIgE (AUC: 52.3%) (p < 0.05). Conclusion: Along with the determination of the diagnostic values of communities, the rapid and accurate diagnosis of the children with a food allergy will be ensured, and the patient follow-up will be made easier (AU)


No disponible


Assuntos
Humanos , Criança , Hipersensibilidade a Ovo/imunologia , Imunoglobulina E/análise , Anafilaxia/imunologia , Testes Cutâneos/métodos , Turquia/epidemiologia , Estudos Retrospectivos , Valor Preditivo dos Testes , Hipersensibilidade Alimentar/imunologia
20.
Allergol. immunopatol ; 45(4): 362-368, jul.-ago. 2017. tab
Artigo em Inglês | IBECS | ID: ibc-165096

RESUMO

Objectives: The aim of the present study was to determine the prevalence and risk factors of allergic diseases in preschool children from one of the biggest cities in the Mediterranean Region of Turkey. Methods: The study population included 396 preschool children attending to urban daycare centres in Mersin. In the first stage, a comprehensive standardised questionnaire modified from the International Study of Asthma and Allergies in Childhood (ISAAC) was employed. In the second stage, serum food and inhalant specific IgE, and skin tests were performed in 45 children with frequent wheezing and 28 children with no wheezing. Results: The prevalence of ever wheezing, current wheezing, physician-diagnosed asthma, allergic rhinitis and eczema were 53% (210), 33.3% (132), 27.3% (108), 13.4% (53) and 8.3% (33), respectively. A family history of atopy (OR = 2.5, 95% CI: 1.3-4.7, p = 0.004), dampness at home (OR = 2.4, 95% CI: 1.2-4.8, p = 0.008), a history of intestinal parasites (OR = 4.3, 95% CI: 1.7-10.9, p = 0.002), previous history of pneumonia (OR = 6.9, 95% CI: 1.9-25.9, p = 0.004), initiation of complementary foods before the age of three months (OR = 6.1, 95%CI: 1.4-26.9, p = 0.02) and presence of food allergy (OR = 3.1, 95% CI: 1.1-9.2, p = 0.03) were found to be significant risk factors for physician-diagnosed asthma. The risk factors for frequent wheezing were maternal smoking during pregnancy (OR=5.2, 95% CI: 0.9-28.7, p = 0.05) and high serum IgE levels (OR = 2.9, 95% CI: 0.9-9.0, p = 0.05) at borderline significance. Conclusion: Our study was the first epidemiological study in preschool children in the Mediterranean region of Turkey and demonstrated a high prevalence of asthma and allergic diseases, probably related to humid climatic properties in addition to other environmental and genetic factors (AU)


No disponible


Assuntos
Humanos , Masculino , Feminino , Pré-Escolar , Sons Respiratórios , Hipersensibilidade Respiratória/epidemiologia , Turquia/epidemiologia , Fatores de Risco , Inquéritos e Questionários , Estudos de Casos e Controles , Hipersensibilidade Imediata/epidemiologia
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