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1.
Appl. cancer res ; 40(3): [1-5], 25 may 2020. ilus
Artigo em Inglês | LILACS | ID: biblio-1103868

RESUMO

Background: Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-hodgkin's lymphoma. In oral cavity represents approximately 2% of all malignancies. Case presentation: This report describes a rare mandibular involvement of DLBCL. A 56 year-old man was referred for evaluation of left mandible pain. In the anamnesis, the patient informed to be treating tooth pain in lasting 6 months. On oral evaluation, an intense mobility of the left mandibular second molar and a swelling in posterior left mandible were observed. Computed tomography showed a large osteolytic lesion affecting both mandibular body and ramus. An incisional biopsy was performed and according to histopathological and imumnohistochemical features, DLBCL was diagnosed. The treatment consisted of 8 cycles of R-CHOP and adjuvant radiotherapy. He is asymptomatic after 6 years. Conclusion: This case showed a rare bone presentation of DLBCL and such tumor should be considered as differential diagnosis of osteolytic lesion of the mandible.


Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Linfoma não Hodgkin , Neoplasias Mandibulares , Linfoma Difuso de Grandes Células B
2.
Autops. Case Rep ; 9(3): e2019090, July-Sept. 2019. ilus, graf
Artigo em Inglês | LILACS | ID: biblio-1020995

RESUMO

Richter transformation (RT), or Richter syndrome, is defined as the transformation of chronic lymphocytic leukemia (CLL) to an aggressive B-cell lymphoma. The vast majority, up to 99%, transform into diffuse large B-cell lymphoma (DLBCL), with a small subset (<1%) becoming classical Hodgkin lymphoma. Approximately half of RT cases progress through a pathway involving dysregulation of C-MYC. High-grade B-cell lymphoma (HGBL) is a recent diagnostic category of aggressive B-cell lymphomas set forth in the updated 2017 WHO Classification of Hematopoietic and Lymphoid Tissues. HGBL with MYC and BCL2 and/or BCL6 rearrangements, formerly "double-hit" and "triple-hit" lymphomas, comprise the majority of HGBL cases. Patients with HGBL have a worse prognosis than those with diffuse large B-cell lymphoma. We present a case of RT with rearrangements of MYC and BCL6. To our knowledge, there are no reported cases of RT with a "double-hit" lymphoma genotype.


Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Linfoma Difuso de Grandes Células B/patologia , Linfoma não Hodgkin , Leucemia Linfocítica Crônica de Células B , Citogenética
3.
Autops. Case Rep ; 9(3): e2019109, July-Sept. 2019. ilus
Artigo em Inglês | LILACS | ID: biblio-1021053

RESUMO

Primary intraosseous non-Hodgkin lymphoma in the mandible is uncommon, representing about 0.6% of all extranodal lymphomas. We present the case of a 51-year-old male with a 4-month complaint of mandibular swelling and paresthesia, which had been previously submitted to an unsuccessful periodontal treatment. The intra-oral evaluation showed an extensive swelling with teeth mobility in the right mandible body. The panoramic radiography and computed tomography images showed an extensive osteolytic lesion. An incisional biopsy was performed and the histopathological and immunohistochemical analysis established the diagnosis of diffuse large B-cell lymphoma. The treatment included six cycles of chemotherapy with complete remission. The patient is under the seventh month of follow-up with no evidence of relapse. Although uncommon in the oral cavity, lymphoma should be considered in the differential diagnosis.


Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Linfoma Difuso de Grandes Células B/patologia , Neoplasias de Cabeça e Pescoço/patologia , Linfoma não Hodgkin , Medicina Bucal , Diagnóstico Diferencial , Mandíbula
4.
Rev. colomb. cancerol ; 22(4): 146-150, oct.-dic. 2018. tab, graf
Artigo em Espanhol | LILACS | ID: biblio-985456

RESUMO

Resumen Entre los linfomas de la zona gris (LZG) encontramos neoplasias con características compartidas entre un linfoma difuso de células B grandes (LDCBG) y un linfoma de Hodgkin clásico (LHC). Lo poco habitual de la patología combinado con la heterogenicidad de la enfermedad, su reciente descripción como entidad específica que conlleva a dificultad y reto diagnóstico, así como la falta de suficiente experiencia terapéutica hacen de la enfermedad una entidad compleja de difícil diagnóstico y reto terapéutico que justifica su descripción continua. Se presenta una paciente con fiebre de un mes sin respuesta al manejo inicial, se estudió y realizó biopsia de ganglio inguinal izquierdo con resultado diagnóstico de LZG con características intermedias entre LDCBG y LHC. Aunque no existen guías establecidas para el manejo de esta entidad, la evidencia actual sugiere mejor respuesta en tratamientos dirigidos a LDCBG, misma terapia empleada en esta paciente con la cual se obtuvo respuesta favorable.


Abstract In the grey zone lymphomas (GZL), there are overlapping characteristics between diffuse large B-cell lymphoma (DLBCL) and classic Hodgkin lymphoma (CHL). The unusual nature of the pathology combined with the heterogeneity of the disease, its recent description as a specific entity, its diagnostic difficulty, and the lack of sufficient therapeutic experience justifies its continuous description. The case is presented of a patient with a fever of one month onset, with no response to initial management. A left inguinal lymph node biopsy reported a diagnosis of GZL with intermediate characteristics between DLBCL and CHL. Although there are no established guidelines for the management of this condition, the current evidence suggests a better response in treatments meant for diffuse large B-cell lymphoma. This same therapy was used in this patient, with a favourable clinical outcome.


Assuntos
Humanos , Terapêutica , Doença de Hodgkin , Linfoma Difuso de Grandes Células B , Diagnóstico
5.
Rev. colomb. cancerol ; 22(4): 143-145, oct.-dic. 2018. graf
Artigo em Espanhol | LILACS | ID: biblio-985455

RESUMO

Resumen El linfoma difuso de células grandes B (LDCGB) es el tipo de linfoma más frecuente, constituyendo un 35% de todos los casos de linfoma no Hodgkin (LNH). El linfoma no-Hodgkin primario de bazo (LNHPB) presenta una incidencia menor al 1% de todos los linfomas. Los linfomas doble hit están relacionados con el reordenamiento del gen MYC asociado a otra alteración molecular. Tienden a presentarse en varones de edad avanzada y se caracterizan principalmente por su comportamiento agresivo.


Abstract Diffuse Large-cell Lymphoma B (DLCLB) is the most common type of lymphoma, constituting 35% of all cases of Non-Hodgkin's Lymphoma (NHL). Primary Splenic Non-Hodgkin Lymphoma (PS-NHL) has an incidence of less than 1% of all lymphomas. The ''double hit'' lymphomas are related to the rearrangement of the MYC gene associated with another molecular alteration. They used to appear in older men and are mainly characterised by their aggressive behaviour.


Assuntos
Humanos , Masculino , Idoso , Idoso de 80 Anos ou mais , Baço , Genes myc , Agressão , Prognóstico , Linfoma não Hodgkin , Linfoma Difuso de Grandes Células B
7.
Rev. cientif. cienc. med ; 21(2): 42-46, 2018. ilus
Artigo em Espanhol | LILACS | ID: biblio-1003797

RESUMO

El linfoma difuso de células B grandes, es una neoplasia maligna linfoproliferativa caracterizada por la reproducción monoclonal de linfocitos de la estirpe B en diferentes órganos y tejidos. Se describe el caso de un paciente femenino de 63 años de edad, quien ingresa al servicio de urgencias por cuadro de dolor abdominal, asociado a pérdida de peso y presencia de melenas. Durante la hospitalización presenta cuadro de obstrucción intestinal y agravamiento del cuadro clínico, por lo que se indica realizar laparotomía exploratoria en donde se encuentra una gran masa con múltiples ganglios en meso de yeyuno de aspecto tumoral. El estudio de patología con inmunohistoquímica de la muestra reporta reactividad difusa para CD20 y para vimentina, además de CD3 y BCL2, hallazgos compatibles con Linfoma de células B grandes, un linfoma no Hodgkin gastrointestinal de presentación infrecuente en yeyuno.


Diffuse large B-cell lymphoma is a malignancy lymphoproliferative characterized by monoclonal lymphocytes B strain reproduction in different organs and tissues. This article is a case report of a female 63-year-old, who admitted to the emergency room with abdominal pain associated with weight loss and presence of manes. During hospitalization, she presents intestinal obstruction associated with clinical worsening and indicating completion of Laparotomy Diagnostics where it's found a large malignant tumor mass with multiple nodes in meso aspect jejunal tumor. The study of pathology with immunohistochemistry of the sample reports diffuse reactivity for CD20 and for vimentin in addition to CD3 and BCL2, compatible findings with large B cell lymphoma, gastrointestinal Non-Hodgking lymphoma of jejunum uncommon presentation.


Assuntos
Humanos , Feminino , Pessoa de Meia-Idade , Linfoma Difuso de Grandes Células B , Cirurgia Geral/métodos , Neoplasias
9.
Gastroenterol. latinoam ; 29(supl.1): S21-S23, 2018.
Artigo em Espanhol | LILACS | ID: biblio-1117633

RESUMO

The gastrointestinal lymphoid system plays a relevant role. The daily and continuous interaction between gastrointestinal lymphocytes with food and intestinal microbes requires precise functioning. The pathologic spectrum of lymphocyte malfunction results in lymphomas. MALT lymphoma is the most frequently diagnosed lymphoma, but there are other lymphoproliferative diseases such as diffuse large B cell lymphoma, mantle cell lymphoma and T associated lymphoma. The gastroenterologist and the endoscopist need to know these diseases in detail to achieve early diagnosis and treatment.


El sistema linfoide de defensa abdominal tiene un relevante rol en el buen funcionamiento sistémico. La interacción diaria y continua con patógenos alimentarios y microbios comensales intestinales precisa un estrecho funcionamiento. Las alteraciones linfoides clonales favorecen el desarrollo de linfomas de diversos tipos. Si bien, el linfoma asociado a tejido linfoide de mucosas (MALT) es el más conocido en contexto de su asociación con Helicobacter pylori, el tracto gastrointestinal se puede ver afectado por otros linfomas como el linfoma difuso de células grandes B y linfomas indolentes como el linfoma folicular, el linfoma del manto y el linfoma T asociado a enteropatía. El gastroenterólogo y endoscopista precisan conocer en detalle estas entidades para un oportuno diagnóstico y adecuado tratamiento.


Assuntos
Humanos , Linfoma Difuso de Grandes Células B/diagnóstico , Linfoma Difuso de Grandes Células B/terapia , Linfoma de Célula do Manto/diagnóstico , Linfoma de Célula do Manto/terapia , Gastroenteropatias/diagnóstico , Gastroenteropatias/imunologia , Fatores de Risco , Helicobacter pylori , Infecções por Helicobacter/complicações , Trato Gastrointestinal/patologia , Linfoma de Células T Associado a Enteropatia/diagnóstico , Linfoma de Células T Associado a Enteropatia/terapia , Gastroenteropatias/patologia
10.
Rev. Hosp. Ital. B. Aires (2004) ; 37(4): 146-148, dic. 2017. ilus
Artigo em Espanhol | LILACS | ID: biblio-1095758

RESUMO

El linfoma difuso de células B grandes (LDCBG) es el linfoma más frecuente. La presentación clínica puede ser nodal o extranodal y sus síntomas dependen de la localización tumoral; en la mayoría de los casos están asociados a algún tipo de inmunodeficiencia. Referiremos un caso de LDCBG de presentación atípica en una localización muy infrecuente. Es importante tener en cuenta estas situaciones, ya que pueden simular otros procesos patológicos, retrasando así su correcto diagnóstico y por lo tanto un adecuado tratamiento. (AU)


Diffuse large cell lymphoma B (LDCBG) is the most common type of lymphoma. It´s clinical presentation can be nodal or extranodal and it's symptoms depend where the tumor is located and whether is associated or not with an immunodeficiency disease. We present an atypical presentation of a LDCBG in a very unusual location. It´s important to consider these kind of appearance, as they can mimic other oral pathological processes, delaying their correct diagnosis and therefore an appropriate treatment. (AU)


Assuntos
Humanos , Masculino , Idoso , Linfoma não Hodgkin/diagnóstico , Neoplasias Gengivais/diagnóstico por imagem , Linfoma Difuso de Grandes Células B/diagnóstico , Linfoma não Hodgkin/classificação , Linfoma não Hodgkin/etiologia , Neoplasias Bucais/diagnóstico , Linfoma Difuso de Grandes Células B/terapia , Linfoma Difuso de Grandes Células B/diagnóstico por imagem , Soronegatividade para HIV/imunologia , Herpesvirus Humano 4/imunologia , Úlceras Orais/patologia , Mucosa Bucal/patologia
11.
Metro cienc ; 25(1): 32-35, Jun. 2017.
Artigo em Espanhol | LILACS | ID: biblio-986637

RESUMO

El linfoma difuso de células grandes B (LDCGB) abarca 25 a 40% del total de los linfomas no Hodgkin (LNH) y es el subtipo histológico más frecuente en el mundo. En Ecuador, el LDCGB corresponde al 49% del total de los casos de LNH. La Organización Mundial de la Salud (OMS) planteó, en 2008, una clasificación que incluye variantes morfológicas y subtipos moleculares e inmunofenotípicos. Los subtipos inmunofenotípicos se identifican según el algoritmo de Hans (CD10, Bcl-6 y MUM-1) y se clasifican, con fines pronósticos en: centro germinal (CG) y no-centro germinal (NCG). Los nuevos hallazgos de caracterización molecular del LDCGB (como traslocaciones cromosómicas recurrentes del myc, Bcl2 y Bcl-6) permiten desarrollar terapias blanco.(AU)


Diffuse large B-cell lymphoma (DLBCL) makes up from 25% to 40% of all non-Hodgkin lymphomas (NHL) and is the most common histologic subtype worldwide. In Ecuador, DLBCL amounts to 49% of all NHL cases. In 2008, the World Health Organization (WHO) put forth a classification that includes morphological variants and molecular and immunophenotypic subtypes. The immunophenotypic subtypes are identified by the Hans algorithm (CD10, Bcl-6, MUM-1) and are classified as germinal center (GC) and nongerminal center (NGC). The new molecular characterization findings of LDCGB as recurrent chromosomal translocations of myc, Bcl2 and Bcl-6, allow the development of target therapies.(AU)


Assuntos
Humanos , Linfoma não Hodgkin , Linfoma Difuso de Grandes Células B , Nanomedicina Teranóstica , Epidemiologia , Tratamento Farmacológico
12.
Medicina (Ribeiräo Preto) ; 50(2): 119-122, mar.-abr. 2017. ilus
Artigo em Português | LILACS | ID: biblio-879709

RESUMO

Relatamos o caso de mulher, 32 anos, branca, previamente hígida, atendida com corrimento vaginal e metrorragia há 3 meses. Exame colpocitológico descreveu esfregaço intensamente hemorrágico e lesão intraepitelial de alto grau com displasia acentuada (NIC III). Ultrassonografia transvaginal e ressonância magnética da pelve caracterizaram aumento dimensional do colo uterino, exibindo aspecto em "barril", por processo expansivo difuso de aspecto infiltrativo. Estudo anatomopatológico e imunohistoquímico de biopsia do colo uterino revelou um linfoma não Hodgkin difuso de grandes células B. (AU)


We report the case of a woman, 32 years old, white, previously healthy, presenting vaginal discharge and metrorrhagia for three months. Pap smear described intensely hemorrhagic smear and high-grade squamous intraepithelial lesions with severe dysplasia (CIN III). Transvaginal ultrasound and MRI of the pelvis characterized an increase in the dimensions of the cervix, displaying aspect "barrel" due process of expansive diffuse infiltrative appearance. The histopathological and immunohistochemistry of the cervical biopsy showed a diffuse non-Hodgkin's lymphoma large B cell. (AU)


Assuntos
Adulto , Bezoares , Colo do Útero/diagnóstico por imagem , Linfoma Difuso de Grandes Células B
14.
Bogotá; Ministerio de Salud y Protección Social; 2017. 706 p.
Monografia em Espanhol | LILACS, BIGG | ID: biblio-964194

RESUMO

Esta guía esta dirigida al personal de la salud involucrado directamente en la atención de pacientes adultos mayores de 18 años con sospecha o diagnóstico de linfoma no Hodgkin B difuso de célula grande (Linfoma B difuso de células grandes), linfoma folicular (LF), linfoma de células del manto (LCM) y linfoma Hodgkin (LH), y a las instancias administrativas, empresas aseguradoras y entes gubernamentales involucrados en la generación de políticas en salud. Esta GPC basada en la evidencia incluye los temas de diagnóstico y tratamiento del Linfoma B difuso de células grandes, LF, LM y LH, bajo la perspectiva del Sistema General de Seguridad Social en Salud colombiano. Objetivos: Determinar los métodos diagnósticos más apropiados en pacientes con LBDCG para garantizar un diagnóstico preciso que permita una adecuada selección del tratamiento; Establecer las líneas de tratamiento en pacientes con LF para disminuir la heterogeneidad en la atención y mejorar los resultados del tratamiento; Determinar los esquemas de tratamiento de primera línea para pacientes con LCM en diferentes grupos de edad para disminuir la heterogeneidad y mejorar los resultados del mismo; y Mejorar la supervivencia libre de enfermedad y la supervivencia global de los pacientes adultos con LH.


Assuntos
Humanos , Gravidez , Adulto , Doença de Hodgkin/diagnóstico , Doença de Hodgkin/terapia , Infecções por HIV , Linfoma Folicular/diagnóstico , Linfoma Folicular/terapia , Linfoma Difuso de Grandes Células B/diagnóstico , Linfoma Difuso de Grandes Células B/terapia , Linfoma de Célula do Manto/diagnóstico , Linfoma de Célula do Manto/terapia
15.
Rev. chil. obstet. ginecol ; 81(5): 399-405, 2016. ilus
Artigo em Espanhol | LILACS | ID: biblio-830150

RESUMO

Antecedentes: El linfoma no Hodgkin de ovario es una patología infrecuente, más aun el ovárico primario. Caso Clínico: Presentamos el caso de una paciente con antecedente de diverticulitis aguda y varios episodios posteriores de dolor abdominal agudo, fiebre y aumento de reactantes de fase aguda con pruebas de imagen no concluyentes. A pesar de la buena respuesta inicial al tratamiento antibiótico, durante uno de los episodios la paciente precisa intervención quirúrgica urgente. Durante la intervención se halla una enfermedad tumoral avanzada con diagnóstico histológico de linfoma difuso de células grandes B. Conclusión: En el diagnóstico diferencial ante una sintomatología similar a la de nuestra paciente, se debería tener presente la posibilidad de un linfoma ovárico, a pesar de su baja incidencia.


Background: Non-Hodgkin's lymphoma of the ovary is an infrequent pathology, even more primary one. Clinical case: We report a patient with a history of acute diverticulitis and several episodes of acute abdominal pain, fever and increased acute phase reactants with inconclusive imaging tests. Patient required urgent surgery during one episode despite a good initial response to antibiotic therapy. A locally advanced tumour disease was found in surgical intervention which was diagnosed as a diffuse large B-cell lymphoma. Conclusion: In the differential diagnosis in a manner similar to that of our patient symptoms, we should keep in mind the possibility of an ovarian lymphoma despite their low incidence.


Assuntos
Humanos , Feminino , Pessoa de Meia-Idade , Linfoma Difuso de Grandes Células B/diagnóstico , Linfoma Difuso de Grandes Células B/cirurgia , Neoplasias Ovarianas/diagnóstico , Neoplasias Ovarianas/cirurgia , Diagnóstico Diferencial , Linfoma Difuso de Grandes Células B/complicações , Neoplasias Ovarianas/complicações
16.
Rev. bras. hematol. hemoter ; 38(3): 247-251, 2016. tabela, gráfico
Artigo em Inglês | LILACS | ID: biblio-837039

RESUMO

Background The clinical course of gastric lymphoma is heterogeneous and clinical symptoms and some factors have been related to prognosis. Objective The present study aims to identify prognostic factors in gastric diffuse B-cell non-Hodgkin lymphoma diagnosed and treated in different countries. Methods A consecutive series of gastric diffuse B-cell non-Hodgkin lymphoma patients diagnosed and treated in Brazil, Portugal and Italy, between February 2008 and December 2014 was evaluated. Results Of 104 patients, 57 were female and the median age was 69 years (range: 28­88). The distribution of the age-adjusted international prognostic index was 12/95 (13%) high risk, 20/95 (21%) high-intermediate risk and 63/95 (66%) low/low-intermediate risk. Symptoms included abdominal pain (63/74), weight loss (57/73), dysphagia (37/72) and nausea/vomiting (37/72). Bulky disease was found in 24% of the cases, anemia in 33 of 76 patients and bleeding in 22 of 72 patients. The median follow-up time was 25 months (range: 1­77 months), with 1- and 5-year survival rates of 79% and 76%, respectively. The multivariate Cox Regression identified the age-adjusted international prognostic index as a predictor of death (hazard risk: 3.62; 95% confidence interval: 2.21­5.93; p-value <0.0001). Conclusions This series identified the age-adjusted international prognostic index as predictive of mortality in patients treated with conventional immunochemotherapy.


Assuntos
Humanos , Masculino , Feminino , Neoplasias Gástricas , Linfoma Difuso de Grandes Células B , Prognóstico
18.
Arch. argent. dermatol ; 66(1): 1-4, ene.-feb. 2016. ilus
Artigo em Espanhol | LILACS | ID: biblio-913718

RESUMO

Los linfomas cutáneos de células B son un grupo heterogéneo de linfomas que se presentan en piel sin evidencia de compromiso extracutáneo al momento del diagnóstico y corresponden entre 20% al 25% de los linfomas cutáneos primarios. Presentamos un caso de un linfoma primario cutáneo difuso de células B grandes, tipo pierna en una anciana, con mala respuesta al tratamiento (AU)


Primary cutaneous B-cell lymphomas are a heterogeneous group of lymphomas occurring in the skin without extracutaneous involvement at time of diagnosis and constitute about 20-25% of primary lymphomas. A case of primary cutaneous diffuse large B-cell lymphoma, leg type, in an elderly woman with a poor response to treatment is reported (AU)


Assuntos
Humanos , Feminino , Pessoa de Meia-Idade , Neoplasias Cutâneas/patologia , Linfoma Difuso de Grandes Células B/diagnóstico , Cuidados Paliativos , Radioterapia
19.
Arch. argent. pediatr ; 113(4): e207-e210, ago. 2015. ilus, graf, tab
Artigo em Espanhol | LILACS, BINACIS | ID: lil-757048

RESUMO

La hipercalcemia asociada a procesos tumorales es un hallazgo poco frecuente en la edad pediátrica. El manejo terapéutico va encaminado a favorecer la calciuresis con diversos métodos farmacológicos e, incluso, técnicas de depuración extrarrenal. El objetivo de la exposición de este caso clínico es presentar a un paciente con hipercalcemia grave refractaria, que solo respondió a un tratamiento etiológico precoz con el empleo de quimioterapia, y se evitaron así las posibles complicaciones secundarias a dicha alteración electrolítica.


Hypercalcemia as a paraneoplastic syndrome is rare in children. Therapeutic management is aimed at promoting calciuresis with various pharmacological methods, even with extrarenal purification techniques. The aim of presenting this case is to highlight the importance of early etiologic treatment through chemotherapy as an urgent treatment in a refractory and severe hypercalcemia case, in order to avoid possible secondary complications due to this electrolyte disturbance.


Assuntos
Humanos , Masculino , Criança , Síndromes Paraneoplásicas/etiologia , Linfoma Difuso de Grandes Células B/complicações , Emergências , Hipercalcemia/etiologia
20.
Rev. méd. Chile ; 143(8): 1076-1080, ago. 2015. ilus
Artigo em Espanhol | LILACS | ID: lil-762674

RESUMO

Intravascular lymphoma is a rare subtype of extranodal diffuse large B-cell lymphoma characterized by clonal proliferation of lymphocytes inside of small and medium caliber vessels. Its incidence is estimated at one case per million. The clinical picture is very variable, but frequently has skin and central nervous system involvement. It is diagnosed by demonstrating pathological blood vessel infiltration by lymphoma cells. We report a 44 years old male presenting with fever, malaise and erythematous lesions in the abdominal wall. An abdominal wall biopsy showed dilated vascular vessels with atypical cells in their lumen, compatible with large B-cell intravascular lymphoma. He was treated with rituximab, cyclophosphamide, adriamycin, vincristine and prednisone and an autologous hematopoietic stem cell transplantation, achieving a complete remission that has lasted two years.


Assuntos
Adulto , Humanos , Masculino , Linfoma Difuso de Grandes Células B/patologia , Neoplasias Vasculares/patologia , Parede Abdominal/irrigação sanguínea , Biópsia , Eritema/complicações , Transplante de Células-Tronco Hematopoéticas , Linfoma Difuso de Grandes Células B/terapia , Indução de Remissão , Neoplasias Vasculares/terapia
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