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Braz. j. microbiol ; 49(supl.1): 246-259, 2018. tab, graf
Artigo em Inglês | LILACS | ID: biblio-974333


ABSTRACT Bacterial spot is an important disease of pepper in Bulgaria and Macedonia. For characterization of Xanthomonas species associated with bacterial spot, 161 strains were collected from various field pepper-growing regions. Among them, 131 strains were identified as Xanthomonas euvesicatoria and 30 as Xanthomonas vesicatoria using species-specific primers and polymerase chain reaction followed by restriction fragment length polymorphism analysis. To assess the genetic diversity of the strains, two methods (Random Amplified Polymorphic DNA and Repetitive Element Palindromic-Polymerase Chain Reaction) were applied. Discriminatory index was calculated and analysis of molecular variance was carried out.Combined random amplified polymorphic DNA analysis of the X. euvesicatoria strains with primers CUGEA-4 and CUGEA-6 had greater discriminative power (0.60) than repetitive element palindromic-polymerase chain reaction with ERIC and BOX A1R primers, which makes this method applicable for strain diversity evaluation. Discrimination among the X. vesicatoria strains was achieved by the use of ERIC primers and only for the Bulgarian strains. The results demonstrated that X. euvesicatoria was more diverse than X. vesicatoria and heterogeneity was observed mainly in the Bulgarian populations. According to the analysis of molecular variance, genetic variations in X. euvesicatoria were observed among and within populations from different regions, while the differences between the two countries were minor. Following the principal coordinates analysis, a relation between the climatic conditions of the regions and a genetic distance of the populations may be suggested.

Doenças das Plantas/microbiologia , Xanthomonas/isolamento & purificação , Xanthomonas/genética , Capsicum/microbiologia , Filogenia , Variação Genética , Xanthomonas/classificação , Xanthomonas/fisiologia , Bulgária , Reação em Cadeia da Polimerase , Primers do DNA/genética , Grécia
An. bras. dermatol ; 91(5): 601-603, Sept.-Oct. 2016. tab
Artigo em Inglês | LILACS | ID: biblio-827758


Abstract: Background: Bullous pemphigoid (BP) is a chronic, autoimmune blistering skin disease that affects patients' daily life and psychosocial well-being. Objective: The aim of the study was to evaluate the quality of life, anxiety, depression and loneliness in BP patients. Methods: Fifty-seven BP patients and fifty-seven healthy controls were recruited for the study. The quality of life of each patient was assessed using the Dermatology Life Quality Index (DLQI) scale. Moreover, they were evaluated for anxiety and depression according to the Hospital Anxiety Depression Scale (HADS-scale), while loneliness was measured through the Loneliness Scale-Version 3 (UCLA) scale. Results: The mean DLQI score was 9.45±3.34. Statistically significant differences on the HADS total scale and in HADS-depression subscale (p=0.015 and p=0.002, respectively) were documented. No statistically significant difference was found between the two groups on the HADS-anxiety subscale. Furthermore, significantly higher scores were recorded on the UCLA Scale compared with healthy volunteers (p=0.003). Conclusion: BP had a significant impact on quality of life and the psychological status of patients, probably due to the appearance of unattractive lesions on the skin, functional problems and disease chronicity.

Humanos , Masculino , Adulto , Pessoa de Meia-Idade , Idoso , Ansiedade/psicologia , Qualidade de Vida/psicologia , Penfigoide Bolhoso/psicologia , Depressão/psicologia , Solidão/psicologia , Índice de Gravidade de Doença , Estudos de Casos e Controles , Inquéritos e Questionários , Grécia
An. bras. dermatol ; 91(2): 160-166, Mar.-Apr. 2016. tab, graf
Artigo em Inglês | LILACS | ID: lil-781364


Abstract BACKGROUND: Psoriasis is a common, chronic, recurrent, immune-mediated disorder of the skin and joints. It can have a significant negative impact on the physical, emotional and psychosocial wellbeing of affected patients. OBJECTIVES: To measure improvement in health-related QoL (HRQoL) in Greek patients with psoriasis vulgaris after a month of treatment with calcipotriol-betamethasone dipropionate gel; and evaluate adherence to treatment parameters. METHODS: The study included 394 psoriasis vulgaris patients from 16 private dermatological practices in Greece, all treated with calcipotriol-betamethasone dipropionate gel. They were evaluated at the first visit and after 4 weeks. Moreover, they completed the Dermatology Life Quality Index (DLQI), while other data such as disease severity, subjective symptoms and adherence, were collected. RESULTS: At week 4, the DLQI median was reduced by 3.5 points from the baseline (p<0.001; baseline and week 4 median: 4.5 and 1.0 respectively). Pruritus and sleep disorders also improved (p<0.001). Furthermore, 90.1% of the subjects fully adhered to treatment, with a 97.1% mean level of compliance. CONCLUSIONS: The convincing clinical results, with a distinct improvement in HRQoL, plus the high level of adherence due to its advantageous physical properties, make the calcipotriol-betamethasone dipropionate gel formulation an important, effective and well-tolerated topical therapy to treat psoriasis.

Humanos , Masculino , Feminino , Adolescente , Adulto , Pessoa de Meia-Idade , Idoso , Adulto Jovem , Psoríase/tratamento farmacológico , Qualidade de Vida , Calcitriol/análogos & derivados , Betametasona/análogos & derivados , Fármacos Dermatológicos/uso terapêutico , Adesão à Medicação/estatística & dados numéricos , Psoríase/patologia , Fatores de Tempo , Índice de Gravidade de Doença , Calcitriol/uso terapêutico , Betametasona/uso terapêutico , Estudos Prospectivos , Inquéritos e Questionários , Resultado do Tratamento , Estatísticas não Paramétricas , Combinação de Medicamentos , Adesão à Medicação/psicologia , Géis , Grécia
An. bras. dermatol ; 90(6): 841-845, Nov.-Dec. 2015. tab
Artigo em Inglês | LILACS | ID: lil-769518


Abstract: BACKGROUND: Psoriasis is a common, long-term skin disease associated with high levels of psychological distress and a considerable adverse impact on life. The effects of psoriasis, beyond skin affliction, are seldom recognized and often undertreated. OBJECTIVE: The aim of the study is to evaluate the quality of life, anxiety and depression, self-esteem and loneliness in patients with psoriasis. METHODS: Eighty-four patients with psoriasis were enrolled in the study. The quality of life, depression and anxiety, loneliness and self-esteem of the patient were assessed using the Dermatology Life Quality Index, Hospital Anxiety and Depression Scale, the UCLA loneliness Scale (UCLA-Version 3) and Rosenberg's Self-esteem Scale, respectively. RESULTS: The Dermatology Quality of Life Index score among psoriasis patients was 12.61 ± 4.88. They had statistically significantly higher scores according to the Hospital Anxiety and Depression Scale -anxiety subscale (p=0.032)-compared with healthy volunteers. Moreover, a statistically significant difference was found between the two groups concerning the UCLA-scale (p=0.033) and RSES-scale (p<0.0001). Female patients presented with lower self-esteem than male patients. CONCLUSION: Psoriasis is a distressing, recurrent disorder that significantly impairs quality of life. Therefore, the recognition and future management of psoriasis may require the involvement of multi-disciplinary teams to manage the physical, psychological and social aspects of the condition, as is the case for systemic, long-term conditions.

Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem , Ansiedade/psicologia , Depressão/psicologia , Solidão/psicologia , Psoríase/psicologia , Qualidade de Vida/psicologia , Autoimagem , Estudos de Casos e Controles , Estudos Transversais , Grécia , Testes Psicológicos , Índice de Gravidade de Doença , Fatores Sexuais , Perfil de Impacto da Doença , Isolamento Social , Fatores Socioeconômicos , Inquéritos e Questionários
Estud. psicol. (Campinas) ; 32(3): 547-556, Jul-Sep/2015.
Artigo em Inglês | LILACS | ID: lil-753980


The success of historical fascism in the particular transitional period at the beginning of the 20th century was grounded in its contribution to the successive acceptance and application of the so-called Fordist model for the organization of labor (accompanied by the correspondent social conditions and relations). Historical fascism contributed thus, with its particular way, to establishing a new class compromise between the potentials related with the productive forces and the confinements emanating from the productive relations. This contribution constitutes the "creativity" of fascism. Such a historical perspective on social processes allows us not to fall into the trap of understanding fascism only as a (barbarian) "deception". Fascism cannot be a plain deception, because a "mere deceit" cannot mobilize people. Fascism takes over, adopts real and unfulfilled needs and hopes - which as such constitute resistance to the capitalist arrogance and logic of commodification of everything - and offers its own (fascist, barbarian) solution or fulfillment. Consequently, our responsibility cannot lie in rejecting these needs and hopes (which are basically needs and hopes for security) because of their distorted or "pervert" articulations. Our responsibility lies in the careful peeling of these hopes/demands from their (fascist) enwrapment. Nationalism (from the subalterns!) does not constitute a mere irrational leftover from the past, but contains potentially mystic and romantic pre- or anti-capitalist elements and references. Nationalism obtains its dynamics and persuasion (for the subalterns!) from and for the contemporary societal processes, thus constituting an active, political and actual demand/position within the restructuring of society - which is in itself a moment in the restructuring of capitalism. Herein also the "rational kernel" of the anti-capitalist antithesis by the New Right is founded as counter position to the "neutral"...

O sucesso do fascismo histórico no período de transição, em particular no início do século 20, foi baseado em sua contribuição para a aceitação e aplicação sucessiva do chamado modelo fordista para a organização do trabalho (acompanhada das condições e relações sociais correspondentes). Fascismo histórico contribuiu assim, em sua forma particular, com a criação de um novo compromisso de classe entre os potenciais relacionados com as forças produtivas e as prisões que emanam das relações produtivas. Esta contribuição constitui a "criatividade" do fascismo. Tal perspectiva histórica sobre os processos sociais, não nos permite cair na armadilha de se compreender o fascismo apenas como um (bárbaro) "engano". O fascismo não pode ser um engano simples, porque um "mero engano" não pode mobilizar as pessoas. Fascismo assume, adota necessidades e esperanças reais e não cumpridas - que, como tal, constituem resistência à arrogância capitalista e lógica da mercantilização de tudo -, e oferece a sua própria solução (fascista, bárbara) ou sua realização. Por conseguinte, a nossa responsabilidade não pode mentir em rejeitar essas necessidades e esperanças (que são, basicamente, precisas e esperar pela segurança) por causa de suas articulações distorcidas ou "pervertido". Nossa responsabilidade exige-nos cuidadosas esperanças e demandas de seu (fascista) envolvimento. Nacionalismo (a partir dos subalternos!) não constitui uma mera sobra irracional do passado, mas contém potencialmente elementos anticapitalistas e referencias pré-místicas e românticas. Nacionalismo obtém sua dinâmica e persuasão (para os subalternos!) de e para os processos sociais contemporâneos, constituindo, assim, uma demanda/posição ativa, política e real no âmbito da reestruturação da sociedade - que é em si mesmo um momento na reestruturação do capitalismo. Aqui também o "núcleo racional" da antítese anticapitalista pela Nova Direita é fundada como posição contrária à mercantilização...

Consciência , Grécia , Superego
Arq. neuropsiquiatr ; 73(8): 665-669, 08/2015. tab
Artigo em Inglês | LILACS | ID: lil-753035


Migraine and tension type headache are the two most common primary headaches. The purpose of this study was to detect differences in clinical characteristics and headache triggers and in a Greek cohort of 51 migraineurs and 12 patients with tension-type headache. (TTH) Migraine patients had a significantly lower age at headache onset and frequency, higher mean visual analogue scale (VAS) and greater maximum duration of headache episodes compared to TTH patients. They did not differ from (TTH) patients in quality of headache, laterality of pain, way of headache installation and progression and temporal pattern of headaches. Nausea, vomiting and phonophobia were more frequent in migraine. Triggering of headaches by dietary factors was associated with migraine, whereas there was no difference between the two groups in any of the other headache triggers. Stress, both physical and psychological, were particularly common in both patient groups.

Enxaqueca e cefaleia tipo tensional são as duas cefaleias primárias mais frequentes. O propósito deste estudo foi avaliar as diferenças e características dos fatores desencadeantes destas cefaleias numa coorte grega de 51 pacientes com enxaqueca e 12 com cefaleia tipo tensional. Pacientes com enxaqueca tinham uma idade significativamente menor por ocasião do início da cefaleia e maior frequência, maiores valores de (VAS) e maior duração dos episódios em comparação com os pacientes com (CTT). Não houve diferença entre os pacientes com enxaqueca e (CTT) com relação à qualidade e lateralidade da dor, na forma de instalação e progressão, e no padrão temporal das cefaleias. Náuseas, vômitos e fonofobia foram mais frequentes em enxaqueca. Fatores desencadeantes na dieta estavam associados à enxaqueca, enquanto não houve diferença entre os dois grupos para outros fatores desencadeantes. Estresse físico e psicológico foram particularmente prevalentes em ambos os grupos de pacientes.

Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem , Transtornos de Enxaqueca/etiologia , Cefaleia do Tipo Tensional/etiologia , Idade de Início , Estudos de Coortes , Comportamento Alimentar , Grécia , Fatores Desencadeantes , Estresse Fisiológico , Estresse Psicológico/complicações , Escala de Ansiedade Frente a Teste , Fatores de Tempo , Escala Visual Analógica
Rev. Soc. Bras. Med. Trop ; 48(supl.1): 34-41, 2015. tab, graf
Artigo em Inglês | LILACS | ID: lil-748360


Envenoming snakebites are thought to be a particularly important threat to public health worldwide, especially in rural areas of tropical and subtropical countries. The true magnitude of the public health threat posed by snakebites is unknown, making it difficult for public health officials to optimize prevention and treatment. The objective of this work was to conduct a systematic review of the literature to gather data on snakebite epidemiology in the Amazon region and describe a case series of snakebites from epidemiological surveillance in the State of Amazonas (1974-2012). Only 11 articles regarding snakebites were found. In the State of Amazonas, information regarding incidents involving snakes is scarce. Historical trends show an increasing number of cases after the second half of the 1980s. Snakebites predominated among adults (20-39 years old; 38%), in the male gender (78.9%) and in those living in rural areas (85.6%). The predominant snake envenomation type was bothropic. The incidence reported by the epidemiological surveillance in the State of Amazonas, reaching up to 200 cases/100,000 inhabitants in some areas, is among the highest annual snakebite incidence rates of any region in the world. The majority of the cases were reported in the rainy season with a case-fatality rate of 0.6%. Snakebite envenomation is a great disease burden in the State of Amazonas, representing a challenge for future investigations, including approaches to estimating incidence under-notification and case-fatality rates as well as the factors related to severity and disabilities.

Animais , DNA Mitocondrial/genética , Cervos/classificação , Cervos/genética , Repetições de Microssatélites/genética , Península Balcânica , Biodiversidade , Conservação dos Recursos Naturais , Frequência do Gene , Variação Genética , Genética Populacional , Variação Estrutural do Genoma , Grécia , Filogeografia , Análise de Sequência de DNA , Translocação Genética
Arq. bras. cardiol ; 103(6): 538-545, 12/2014. graf
Artigo em Inglês | LILACS | ID: lil-732167


Our knowledge regarding the anatomophysiology of the cardiovascular system (CVS) has progressed since the fourth millennium BC. In Egypt (3500 BC), it was believed that a set of channels are interconnected to the heart, transporting air, urine, air, blood, and the soul. One thousand years later, the heart was established as the center of the CVS by the Hippocratic Corpus in the medical school of Kos, and some of the CVS anatomical characteristics were defined. The CVS was known to transport blood via the right ventricle through veins and the pneuma via the left ventricle through arteries. Two hundred years later, in Alexandria, following the development of human anatomical dissection, Herophilus discovered that arteries were 6 times thicker than veins, and Erasistratus described the semilunar valves, emphasizing that arteries were filled with blood when ventricles were empty. Further, 200 years later, Galen demonstrated that arteries contained blood and not air. With the decline of the Roman Empire, Greco-Roman medical knowledge about the CVS was preserved in Persia, and later in Islam where, Ibn Nafis inaccurately described pulmonary circulation. The resurgence of dissection of the human body in Europe in the 14th century was associated with the revival of the knowledge pertaining to the CVS. The main findings were the description of pulmonary circulation by Servetus, the anatomical discoveries of Vesalius, the demonstration of pulmonary circulation by Colombo, and the discovery of valves in veins by Fabricius. Following these developments, Harvey described blood circulation.

O conhecimento da anatomofisiologia do Sistema Cardiovascular (SCV) progride desde o quarto milênio AC. No Egito (3500 AC), acreditava-se que um conjunto de canais conectava-se ao coração, transportando ar, urina, ar, sangue e a alma. Mil anos após, o Corpo Hipocrático, na escola médica de Kós, estabeleceu o coração como o centro do SCV, definindo algumas características deste órgão. O SCV transportava sangue via ventrículo direito pelas veias, e o pneuma via ventrículo esquerdo pelas artérias. Duzentos anos depois, em Alexandria, com o aparecimento da dissecção anatômica do corpo humano, Herophilus descobriu que as artérias eram seis vezes mais espessas que as veias, enquanto que Erasistratus descreveu as válvulas semilunares, enfatizando que as artérias eram preenchidas por sangue quando o ventrículo esquerdo se esvaziava. Duzentos anos depois, Galeno demonstrou que as artérias continham sangue, não ar. Com o declínio do Império Romano, todo o conhecimento médico Greco-romano do SCV foi preservado na Pérsia, e posteriormente no Islã, onde Ibn-Nafis descreveu incompletamente a circulação pulmonar. Aqui, deve-se enfatizar a incompleta descrição da circulação pulmonar por Ibn-Nafis. A ressurgência da dissecção do corpo humano na Europa no século XIV é associada ao renascimento do conhecimento do SCV. Os principais marcos foram a descrição da circulação pulmonar por Servetus, as descobertas anatômicas de Vesalius, a demonstração da circulação pulmonar por Colombo, e a descoberta das válvulas das veias por Fabricius. Tal contexto abriu o caminho para Harvey descobrir a circulação do sangue.

História Antiga , História Medieval , Humanos , Anatomia/história , Fenômenos Fisiológicos Cardiovasculares , Sistema Cardiovascular/anatomia & histologia , Fisiologia/história , Cardiologia/história , Egito , Grécia , Ilustração Médica , Mundo Romano
Rev. salud pública (Córdoba) ; 18(1): 54-59, 2014. ilus
Artigo em Espanhol | LILACS | ID: lil-714107


El trabajo recuerda a los Tracios, pueblos de la antigüedad desarrollados desde el tercer milenio antes de Cristo y extendidos en una amplia área que comprendía la parte oriental de la Península de los Balcanes hasta zonas costeras del Asia Menor.La herencia dorada de Homero, Hesiodo y Heródoto, nos permiten conocer el antiguo pueblo que en sentido étnico, hablaba “tracio”, una rama de la familia de las lenguas indoeuropeas. Los mitos griegos que han enriquecido la literatura universal y que colaboran con los hallazgos arqueológicos, nos permiten describir la medicina y los ritos funerarios tracios

This work reminds the people from Thrace and all the other people included under that name, that covered different regions. They developed from the third millenium before Christ. They extended from the oriental part of the Peninsula of Balkan until the costal región of Minor Asia. The golden heritage of Hesiodo, Homero and Herodoto, let us know the old popolution that, in ethnic sense used to talk of “tracio”, an old brank of the family of indoeuropean languages The greek miths that have enriched universal literatura and that used to cooperate in the archeological find. They allow us to describe the tracios medicine and the funeral rites

Humanos , Masculino , Feminino , História Antiga , Rituais Fúnebres , Grécia , Rituais Fúnebres/história
Int. j. morphol ; 31(4): 1328-1330, Dec. 2013.
Artigo em Espanhol | LILACS | ID: lil-702313


Rufus de Éfeso (I d.C.), prominente médico-cirujano y anatomista greco-romano. Experto en anatomia, fisiología, observación clínica, cirugía y en el tratamiento de enfermedades, realizo hallazgos anatómicos y fisiológicos extraordinarios, entre otros permanecen conservados fragmentos de sus obras como: en la nomenclatura de las partes del cuerpo humano, en enfermedades del riñón y la vejiga, así como y en el interrogatorio del paciente.

Rufus of Ephesus (I a.C.), outstanding medical doctor, surgeon and greco-roman anatomist. Expert in anatomy, physiology, clinical observation, surgery and in treatment of the diseases, He realized extraordinary anatomical and physiological findings; among others remain conserved fragments of his works like: In nomenclature of the parts of the human body, In diseases of the kidney and the bladder, and In the interrogation of the patient.

História Antiga , Anatomia/história , História da Medicina , Grécia , Mundo Romano
Rev. paul. pediatr ; 31(3): 350-358, set. 2013. tab, graf
Artigo em Inglês | LILACS | ID: lil-687983


OBJECTIVE: To compare the motor development of infants from three population samples (Brazil, Canada and Greece), to investigate differences in the percentile curves of motor development in these samples, and to investigate the prevalence of motor delays in Brazilian children. METHODS: Observational, descriptive and cross-sectional study with 795 Brazilian infants from zero to 18 months of age, assessed by the Alberta Infant Motor Scale (AIMS) at day care centers, nurseries, basic health units and at home. The Brazilian infants' motor scores were compared to the results of two population samples from Greece (424 infants) and Canada (2,400 infants). Descriptive statistics was used, with one-sample t-test and binomial tests, being significant p≤0.05. RESULTS: 65.4% of Brazilian children showed typical motor development, although with lower mean scores. In the beginning of the second year of life, the differences in the motor development among Brazilian, Canadian and Greek infants were milder; at 15 months of age, the motor development became similar in the three groups. A non-linear motor development trend was observed. CONCLUSIONS: The lowest motor percentiles of the Brazilian sample emphasized the need for national norms in order to correctly categorize the infant motor development. The different ways of motor development may be a consequence of cultural differences in infant care. .

OBJETIVO: Comparar el desarrollo motor de niños de tres muestras poblacionales (Brasil, Canadá y Grecia), verificar las diferencias en las curvas de percentiles del desarrollo motor para esas muestras e investigar la prevalencia de retardos motores en niños brasileños. MÉTODOS: Estudio observacional, descriptivo y transversal, del que participaron 795 niños brasileños con edad entre 0 y 18 meses, evaluados con la Alberta Infant Motor Scale (AIMS) en las escuelas infantiles, maternidades, unidades de salud pública y en domicilio. Los escores motores de niños brasileños fueron comparados a los resultados de investigaciones con los grupos poblacionales de Grecia (424 niños) y de Canadá (2.400 niños). Se utilizó la estadística descriptiva, con las pruebas one-sample t-test y binominal, siendo significante p≤0,05. RESULTADOS: Se observó que el 65,4% de los niños brasileños presentaron desempeño motor normal, aunque con escores medianos más bajos que los otros grupos. En el inicio del segundo año de vida, las diferencias de desempeño entre los niños brasileños, canadienses y griegos se redujeron y, a los 15 meses, el desempeño motor se hizo semejante. Se verificó tendencia de adquisiciones motoras no lineales. CONCLUSIONES: Los percentiles más bajos de la muestra brasileña reforzaron la necesidad de usarse normas nacionales para categorizar adecuadamente el desempeño motor. Los distintos recorridos del desarrollo motor son posiblemente decurrentes de diferencias culturales en el cuidado del niño. .

OBJETIVO: Comparar o desempenho motor de crianças de três amostras populacionais (Brasil, Canadá e Grécia), verificar as diferenças nas curvas de percentis do desenvolvimento motor para essas amostras e investigar a prevalência de atrasos motores em crianças brasileiras. MÉTODOS: Estudo observacional, descritivo e transversal, do qual participaram 795 crianças brasileiras com idade entre zero e 18 meses, avaliadas com a Alberta Infant Motor Scale (AIMS) nas escolas infantis, maternidades, unidades de saúde pública e em domicílio. Os escores motores de crianças brasileiras foram comparados aos resultados de pesquisas com os grupos populacionais da Grécia (424 crianças) e do Canadá (2.400 crianças). Utilizou-se estatística descritiva, com os testes one-sample t-test e binomial, sendo significante p≤0,05. RESULTADOS: Observou-se que 65,4% das crianças brasileiras apresentaram desempenho motor normal, embora com escores médios mais baixos que os outros grupos. No início do segundo ano de vida, as diferenças de desempenho entre as crianças brasileiras, canadenses e gregas diminuíram e, aos 15 meses, o desempenho motor tornou-se semelhante. Verificou-se tendência de aquisições motoras não lineares. CONCLUSÕES: Os percentis mais baixos da amostra brasileira reforçam a necessidade de se usarem normas nacionais para categorizar adequadamente o desempenho motor. As diferentes trajetórias do desenvolvimento motor são possivelmente decorrentes de diferenças culturais no cuidado das crianças. .

Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Desenvolvimento Infantil , Características Culturais , Destreza Motora , Brasil , Canadá , Estudos Transversais , Grécia
An. bras. dermatol ; 87(6): 862-869, Nov.-Dec. 2012. graf, tab
Artigo em Inglês | LILACS | ID: lil-656610


BACKGROUND: Acne vulgaris can severely affect social and psychological functioning. OBJECTIVE: The aim of this study was to investigate the impact of acne vulgaris and its severity on Quality of Life of young adolescents in Greece. METHODS: We conducted a questionnaire based survey among 1560 adolescent between the ages of 11 and 19 years old and 1531 of these were completed. Adolescents with acne filled all the questions including the Children Dermatology Life Quality Index. Adolescents without acne filled the questions about age, family history of acne, stress and smoking. Data were analyzed with Pearson Chi Square test. RESULTS: Acne prevalence was 51.2% affecting both sexes equally. Self reported mild acne was present in 71.2% and moderate-severe acne in 28.8% of the study population. The mean age of the study population was 15.77y. The median score of Children Dermatology Life Quality Index was 4.02. The impact of acne on quality of life is associated with the severity of the acne (p<0.0001). Patients with moderate/severe acne experience greater psychosocial and emotional impairment (p<0.0001). Body image is modified proportionally to the severity of acne (p<0.0001). Symptoms and treatment of acne are factors that also influence their quality of life. Girls and boys are equally affected. Stress and heredity are correlated with acne and its severity (p<0.0001). We didn't find any correlation between smoking and acne. CONCLUSION: Acne affects Quality of Life of young adolescents in Greece. The impact is proportional to the severity of acne. More severe acne is associated with greater effect on quality of life with implications for self esteem, body image and relationships with others.

FUNDAMENTOS: Acne vulgar pode afetar seriamente o funcionamento social e psicológico. OBJETIVO: O objetivo deste estudo foi investigar o impacto da acne vulgar e sua gravidade na Qualidade de Vida de jovens adolescentes na Grécia. MÉTODOS: Nós conduzimos uma pesquisa baseada em questionário entre 1560 adolescentes com idades entre 11 e 19 anos e 1531 destes foram completados. Adolescentes com acne completaram todas as questões incluindo o Children Dermatology Life Quality Index (CDLQI). Adolescentes sem acne completaram as questões sobre idade, história familiar de acne, estresse e tabagismo. Os dados foram analisados pelo teste de chi-quadrado de Pearson. RESULTADOS: A prevalência de acne foi de 51.2%, afetando igualmente ambos os sexos. O auto relato de acne leve estava presente em 71.2% e de acne moderada a grave em 28.8% da população. A idade média da população em estudo foi de 15.77 anos. O escore médio do Children Dermatology Life Quality Index foi de 4.02. O impacto da acne na Qualidade de Vida está associado à gravidade da acne (p<0.0001). Pacientes com acne moderada/grave experimentam maior piora psico-social e emocional (p<0.0001). A imagem corporal é modificada proporcionalmente à gravidade da acne (p<0.0001). Sintomas e tratamento da acne são fatores que também influenciam sua qualidade de vida. Meninas e meninos são afetados igualmente. Estresse e hereditariedade estão correlacionados à acne e sua gravidade (p<0.0001). Nós não encontramos nenhuma correlação entre tabagismo e acne. CONCLUSÃO: Acne afeta a qualidade de vida de jovens adolescentes na Grécia. O impacto é proporcional à gravidade da acne. A acne mais grave está associada a um maior efeito na qualidade de vida com implicações na auto-estima, imagem corporal e relacionamento com outros.

Adolescente , Criança , Feminino , Humanos , Masculino , Adulto Jovem , Acne Vulgar/psicologia , Saúde Mental , Qualidade de Vida/psicologia , Acne Vulgar/epidemiologia , Estudos Transversais , Grécia/epidemiologia , Prevalência , Índice de Gravidade de Doença , Inquéritos e Questionários
West Indian med. j ; 61(1): 28-31, Jan. 2012.
Artigo em Inglês | LILACS | ID: lil-672845


OBJECTIVE: It is known that clinical similarities between Behcet's disease and Familial Mediterranean Fever have led to the hypothesis of a common pathogenesis. Familial Mediterranean Fever is caused by MEFV gene mutations coding for pyrin. Therefore, we examined whether these pyrin mutations are also associated with Behcet's disease. METHODS: Molecular testing for pyrin mutations was performed in 96 unrelated Greek patients with an established diagnosis of Behcet's disease. The results were compared with an analysis for pyrin mutations in 140 unrelated healthy Greek controls. RESULTS:We found no pyrin mutations among the Behcet cases tested; this result is comparable with the control group. CONCLUSIONS: Pyrin gene mutations in Greek patients with Behcet's disease are not more common than those in the general population. This finding is not in agreement with the findings in other populations. It is suggested that screening for pyrin mutations not be included in the evaluation of Greeks suspected to have Behcet's disease.

OBJETIVO:Se sabe que las similitudes clínicas entre la enfermedad de Behçet y la fiebre mediterránea familiar han llevado a la hipótesis de una patogénesis común. La fiebre mediterránea familiar es causada por mutaciones en el gen MEFV que codifica la pirina. Por lo tanto, examinamos si estas mutaciones de la pirina se hallan también asociadas con la enfermedad de Behçet. MÉTODOS: La prueba molecular para la detección de las mutaciones de la pirina se realizó en 96 pacientes griegos no relacionados, y diagnosticados con la enfermedad de Behçet. Los resultados se compararon con un análisis de las mutaciones de la pirina en 140 controles formados por individuos griegos saludables. RESULTADOS: No se encontraron mutaciones de pirina entre los casos de Behçet sometidos a prueba. Este resultado es comparable con el grupo control. CONCLUSIONES: Las mutaciones del gen de la pirina en los pacientes griegos con la enfermedad de Behçet no son más comunes que las de la población general. Este hallazgo no concuerda con los hallazgos en otras poblaciones. Se sugiere que el tamizaje para la detección de las mutaciones de pirina no se incluya en la evaluación de pacientes griegos sospechosos de padecer la enfermedad de Behçet.

Adolescente , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem , Síndrome de Behçet/genética , Proteínas do Citoesqueleto/genética , Estudos de Casos e Controles , Grécia , Mutação
Rev. chil. infectol ; 28(4): 374-380, ago. 2011. ilus
Artigo em Espanhol | LILACS | ID: lil-603070


In the year 430 B.C., at the beginning of the second year of the Peloponessian War, a terrible epidemic fell upon Athens and the most populous cities in Attica. It would last for just over four years and it would kill 100.000 people, a quarter to a third of the population. We know about it through the masterly description made by Thucydides in his History of the Peloponnesian War. His narrative has withstood twenty five centuries due to its medical interest and, above all, its great dramatic force. The description of symptoms and signs, their evolution, and the consequences upon persons and moral and social order has captivated physicians, philologists and classical historians ever since. It has inspired literary works and hundreds of medical articles, with no agreement having been reached upon its cause or consequences, or if it is history or tragedy, or even if there is a single answer to these alternatives.

En el año 430 a.C., al iniciarse el segundo año de la guerra del Pelo-poneso, una terrible epidemia se desató en Atenas y en las ciudades más populosas de Ática. Duraría algo más de cuatro años y morirían unas 100.000 personas, un cuarto a un tercio de la población. Sabemos de ella a través de la magistral descripción que Tucídides hace en su Historia de la Guerra del Peloponeso. Su relato ha perdurado por 25 siglos por su interés médico y, sobre todo, por su gran fuerza dramática. La descripción de los síntomas y signos, su evolución y las consecuencias sobre las personas y sobre el orden social y moral ha cautivado a médicos, filólogos e historiadores. Ha inspirado obras literarias y cientos de artículos sobre la etiología de la plaga sin que hasta el momento exista acuerdo sobre qué fue, si es historia o tragedia, e incluso, si es que hay una respuesta única a estas alternativas.

História Antiga , Humanos , Epidemias/história , Peste/história , Grécia
Iatreia ; 24(1): 90-96, mar. 2011.
Artigo em Espanhol | LILACS | ID: lil-599277


Para comprender cómo se ha enseñado la medicina a través de los tiempos, es necesario apoyarse en los historiadores que han tratado su evolución y, a partir de ellos, indagar sobre las actitudes de los médicos en su posición como docentes y acerca de cómo era la apropiación del conocimiento en cada época por parte de los estudiantes. En este primer artículo se presenta un recorrido sucinto a través de las diferentes épocas históricas para ver los avances y retrocesos de la enseñanza de la medicina, desde el Antiguo Imperio Egipcio (3000-2500 a. C.) con su gran legado en los papiros, continuando con los grandes progresos de la medicina griega, el oscurantismo en la Edad Media y los cambios hasta el siglo XVII.

In order to understand how medicine has been taught through the years, it is necessary to refer to historians who have approached the evolution of medicine. Taking them as a starting point, it is possible to describe the attitudes of doctors in their role as professors, and the ways in which students acquired knowledge at different moments throughout centuries. This article presents a succinct vision of the advances and retrogressions in medical teaching at different historical moments. It starts with the Ancient Egyptian Empire (3000-2500 b. C.) with its big legacy written on papyruses; continues with the enormous progress of Greek medicine and the obscurity of the Middle Ages, and finishes with the advances until the XVII century.

História Antiga , Anatomia/história , Educação Médica , Fisiologia/história , Juramento Hipocrático , História da Medicina , Aprendizagem , Religião e Medicina , Ensino , Grécia , Roma
Int. braz. j. urol ; 36(6): 724-731, Dec. 2010. tab
Artigo em Inglês | LILACS | ID: lil-572420


PURPOSE: To compare the efficacy and safety of the electromagnetic lithotripter in the treatment of pediatric lithiasis to that of the earlier electrohydraulic model. MATERIALS AND METHODS: Two groups of children with lithiasis aged between 10 and 180 months who underwent extracorporeal shock wave lithotripsy (ESWL). In the first group (26 children), ESWL was performed by using the electrohydraulic MPL 9000X Dornier lithotripter between 1994 and 2003 while in the second group (19 children) the electromagnetic EMSE 220 F-XP Dornier lithotripter was used from April 2003 to May 2006. RESULTS: In the first group, 21/26 children (80.7 percent) were stone free at first ESWL session. Colic pain resolved by administration of an oral analgesic in 6 (23 percent), brief hematuria (< 24 h) resolved with increased fluid intake in 5 (19.2 percent), while slightly elevated body temperature (< 38°C) occurred in 4 (15.3 percent). Four children (15.3 percent) failed to respond to treatment and were treated with ureteroscopy. In the second group 18/19 children were completely stone free at first ESWL session (94.7 percent). Complications were infrequent and of minor importance: colic pain treated with oral analgesic occurred in 1 (5.26 percent), brief hematuria (< 24 h), resolved with increased fluid intake in 4 (21 percent) and slightly elevated body temperature (< 38°C) monitored for 48 hours occurred in 6 (31.5 percent). Statistical analysis showed that electromagnetic lithotripter is more efficacious and safer than the earlier electrohydraulic model. CONCLUSIONS: Technological development not only has increased efficacy and safety of lithotripter devices in treating pediatric lithiasis, but it also provided less painful lithotripsy by eliminating the need for general anesthesia.

Adolescente , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Masculino , Litotripsia/métodos , Urolitíase/terapia , Estudos de Viabilidade , Grécia , Estudos Retrospectivos , Fatores de Tempo , Resultado do Tratamento