Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 254
Filtrar
1.
Medicine (Baltimore) ; 99(33): e21536, 2020 Aug 14.
Artigo em Inglês | MEDLINE | ID: mdl-32872000

RESUMO

BACKGROUND: Pain in glossodynia may be severe; it may prevent patients from working, interfere with daily life activities, and necessitate a patient's visit to a medical institution for consultation and treatment. The pain may be described as persistent and burning (tingling, tingling) or stinging. Patients may complain of dry mouth (dryness), which is thought to cause inflammation of the tongue and gingival mucous membranes and increased pain. Medications are prescribed based on the symptoms of glossodynia, and the therapeutic effect is confirmed. However, each drug has side effects, for example, pain may reduce, but drowsiness and dizziness may occur; further, there is always a tendency of drowsiness.On the other hand, Goreisan, a Chinese herbal medicine, has already been used by physicians to treat pain in the oral and maxillofacial regions resulting from rapid changes in air pressure. However, the lack of high-quality clinical research has been of concern, and a randomized clinical trial to investigate the efficacy and safety of Goreisan for treatment of pain in glossodynia is warranted. METHODS/DESIGN: This multicenter, randomized, controlled study will involve patients treated for glossodynia-related pain. In the experimental group, Goreisan will be taken for 12 weeks in combination with conventional treatment. Participants in the control group will not take any Kampo medicine; only the standard treatment will be taken. Subsequently, the degree of pain will be assessed, and saliva tests of all the patients on their first visit will be performed. Goreisan will be taken at a dose of 7.5 g/d (minute 3) for 12 consecutive weeks. Twelve weeks later, the degree of pain of each patient will be assessed. DISCUSSION: The purpose of this study is to investigate the efficacy of Goreisan for pain reduction in patients undergoing treatment for glossodynia-related pain. If pain in glossodynia patients can be reduced by the administration of Goreisan, its candidacy as an alternative treatment for pain in glossodynia can be further supported by more reliable research. TRIAL REGISTRATION: The study was registered in the jRCTs071200017. URL https://jrct.niph.go.jp/latest-detail/jRCTs071200017.


Assuntos
Medicamentos de Ervas Chinesas/uso terapêutico , Glossalgia/tratamento farmacológico , Manejo da Dor/métodos , Humanos , Medicina Kampo , Estudos Multicêntricos como Assunto , Medição da Dor , Ensaios Clínicos Controlados Aleatórios como Assunto
2.
Dent Clin North Am ; 64(2): 379-399, 2020 04.
Artigo em Inglês | MEDLINE | ID: mdl-32111276

RESUMO

Burning mouth syndrome/glossodynia and trigeminal neuropathic conditions can have serious negative impact on a patient's overall quality of life. These conditions are often hard to diagnose and even harder to fully treat and manage, but it is important for dentists/oral and maxillofacial surgeons to be aware of these conditions and modalities of their treatment. Often the only method for arriving at the proper diagnosis is for patients to undergo traditional approaches for treatment of presenting signs and symptoms, and it is the unexpected failure of interventional therapies that leads ultimately to a proper diagnosis.


Assuntos
Síndrome da Ardência Bucal , Glossalgia , Neuralgia , Odontólogos , Humanos , Qualidade de Vida
3.
Artigo em Russo | MEDLINE | ID: mdl-30778036

RESUMO

A case-report of burning mouth syndrome is presented. A 27-year-old man complained of burning pain in the tongue and oral mucosa, taste disorder, and sensory impairment. All symptoms appeared after suffering a cold and had a wave-like course during self-medication with antibiotics. The pain has continued for 8 months. Diagnoses of atypical facial pain, glossodynia or secondary facial pain (craniomandibular dysfunction) were made. The effect of treatment in the hospital (carbamazepine, amitriptyline, haloperidol, phenozepam) was not achieved. A microbial test showed a higher number of pathogenic microbes. The final diagnosis was secondary facial pain (burning mouth syndrome) with concomitant lesions of the oral mucosa (Staphylococcus aureus, Candida sp.). The patient received a combined therapy with the pronounced positive effect.


Assuntos
Síndrome da Ardência Bucal , Glossalgia , Adulto , Dor Facial , Humanos , Masculino , Mucosa Bucal
7.
Pain ; 156(12): 2528-37, 2015 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-26270588

RESUMO

Burning mouth syndrome is characterized by altered sensory qualities, namely tongue pain hypersensitivity. We found that the mRNA expression of Artemin (Artn) in the tongue mucosa of patients with burning mouth syndrome was significantly higher than that of control subjects, and we developed a mouse model of burning mouth syndrome by application of 2,4,6-trinitrobenzene sulfonic acid (TNBS) diluted with 50% ethanol to the dorsum of the tongue. TNBS treatment to the tongue induced persistent, week-long, noninflammatory tongue pain and a significant increase in Artn expression in the tongue mucosa and marked tongue heat hyperalgesia. Following TNBS treatment, the successive administration of the transient receptor potential vanilloid 1 (TRPV1) antagonist SB366791 or neutralizing anti-Artn antibody completely inhibited the heat hyperalgesia. The number of glial cell line-derived neurotrophic factor family receptor α3 (GFRα3)-positive and TRPV1-positive trigeminal ganglion (TG) neurons innervating the tongue significantly increased following TNBS treatment and was significantly reduced by successive administration of neutralizing anti-Artn antibody. The capsaicin-induced current in TG neurons innervating the tongue was enhanced following TNBS treatment and was inhibited by local administration of neutralizing anti-Artn antibody to the tongue. These results suggest that the overexpression of Artn in the TNBS-treated tongue increases the membrane excitability of TG neurons innervating the tongue by increasing TRPV1 sensitivity, which causes heat hyperalgesia. This model may be useful for the study of tongue pain hypersensitivity associated with burning mouth syndrome.


Assuntos
Síndrome da Ardência Bucal/genética , Glossalgia/metabolismo , Hiperalgesia/metabolismo , Proteínas do Tecido Nervoso/genética , Proteínas do Tecido Nervoso/metabolismo , Neurônios/metabolismo , RNA Mensageiro/metabolismo , Língua/metabolismo , Gânglio Trigeminal/metabolismo , Idoso , Idoso de 80 Anos ou mais , Anilidas/farmacologia , Animais , Anticorpos Neutralizantes/farmacologia , Western Blotting , Síndrome da Ardência Bucal/induzido quimicamente , Síndrome da Ardência Bucal/metabolismo , Cinamatos/farmacologia , Modelos Animais de Doenças , Feminino , Receptores de Fator Neurotrófico Derivado de Linhagem de Célula Glial/metabolismo , Glossalgia/induzido quimicamente , Temperatura Alta , Humanos , Hiperalgesia/induzido quimicamente , Masculino , Camundongos , Pessoa de Meia-Idade , Proteínas do Tecido Nervoso/farmacologia , Técnicas de Patch-Clamp , Reação em Cadeia da Polimerase em Tempo Real , Transdução de Sinais , Canais de Cátion TRPV/antagonistas & inibidores , Canais de Cátion TRPV/metabolismo , Língua/efeitos dos fármacos , Gânglio Trigeminal/citologia , Ácido Trinitrobenzenossulfônico/toxicidade
8.
Medicine (Baltimore) ; 94(31): e1163, 2015 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-26252275

RESUMO

Fibromyalgia is a disorder characterized by an abnormal pain regulation. Widespread pain, fatigue, and sleep disturbance are the prevalent symptoms. When unusual symptoms are overbearingly predominant at clinical presentation, the diagnosis becomes challenging.We report on the case of a patient with fibromyalgia, who presented with dysphagia, odynophagia, and glossodynia as prevalent symptoms. Difficulty in swallowing gradually developed over a month prior hospitalization, and worsened progressively so that nourishment and fluid intake were impeded.Because anemia with mild iron deficiency was found, esophagogastroduodenoscopy was performed, but no lesions were seen in the upper digestive tract. Levels of zinc and vitamin B12 were normal. Intense pain at pelvis and the inferior limbs, which was at a first glance referred to as osteoarthrosis, associated with oral symptoms and feeling of being in the clouds allowed us to diagnose fibromyalgia. Amitriptyline was used, with relief of symptoms.Although oropharyngeal symptoms were occasionally reported in fibromyalgia, they are often overlooked. The present case, therefore, testifies the need to consider the diagnosis of fibromyalgia when the patient presents with such symptoms that cannot be readily explained on other grounds.


Assuntos
Transtornos de Deglutição/etiologia , Fibromialgia/diagnóstico , Glossalgia/etiologia , Perda de Peso , Idoso de 80 Anos ou mais , Feminino , Fibromialgia/complicações , Humanos
9.
Eksp Klin Gastroenterol ; (6): 95-8, 2015.
Artigo em Russo | MEDLINE | ID: mdl-26817112

RESUMO

The case of clinical supervision of the patient having polimorbid pathology is presented. One of extraesophageal manifestations of a gastroesophageal reflux disease is the glossalgia. Glossalgia is the polyetiological disease. Treatment needs to be carried out taking into account the factors causing emergence of a glossalgia. In this regard normalization of functions of organs and systems of an organism is provided.


Assuntos
Esôfago/patologia , Refluxo Gastroesofágico , Glossalgia , Idoso , Refluxo Gastroesofágico/complicações , Refluxo Gastroesofágico/patologia , Refluxo Gastroesofágico/terapia , Glossalgia/etiologia , Glossalgia/patologia , Glossalgia/terapia , Humanos , Masculino , Síndrome
10.
Aust Dent J ; 60(3): 412-5, 2015 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-25280059

RESUMO

This is a rare case report of a cerebellopontine angle (CPA) mass mimicking lingual nerve injury after a dental implant placement. Lingual nerve injury is a common complication following dental implant placement. CPA masses are likely to cause symptomatic trigeminal neuralgia, and thus can mimic and be easily confused with oral diseases. We experienced a case of CPA mass mimicking lingual nerve injury after dental implant placement. The patient was a 57-year-old Japanese female who complained of glossalgia. She underwent dental implant placement in the mandible before visiting our clinic. Panoramic x-ray radiography revealed no abnormalities; the salivary flow rate by gum test was 7.0 ml/10 min. She was diagnosed with lingual nerve injury and secondary burning mouth syndrome. Vitamin B12 and oral moisturizer did not provide relief; furthermore, numbness in the lower lip emerged. A Semmes Weinstein test demonstrated elevation of her sensitivity threshold. Finally, magnetic resonance imaging revealed a 20-mm diameter mass in the CPA. The patient is now being followed under conservative management. Our experience underscores the importance of including CPA mass in the differential diagnosis of dental diseases.


Assuntos
Doenças Cerebelares/diagnóstico , Ângulo Cerebelopontino/patologia , Implantes Dentários/efeitos adversos , Traumatismos do Nervo Lingual/diagnóstico , Síndrome da Ardência Bucal/diagnóstico , Diagnóstico Diferencial , Feminino , Seguimentos , Glossalgia/diagnóstico , Humanos , Imagem por Ressonância Magnética , Pessoa de Meia-Idade , Radiografia Panorâmica , Neuralgia do Trigêmeo/diagnóstico
11.
Stomatologiia (Mosk) ; 93(4): 15-9, 2014.
Artigo em Russo | MEDLINE | ID: mdl-25377573

RESUMO

The term "Burning Mouth Syndrome (BMS)" is being used much more often than "Glossodynia", complicating diagnostic and treatment tactic choice. The aim of the study was to determine the difference between "Glossodynia" and "BMS" considering absence or presence of intraoral metal prosthetic devices and burning sensation in the mouth. To establish the frequency of glossodynia and BMS 2355 patient records were analyzed admitting consultation for oral diseases for the last 10 years. Clinically we examined 408 patients aged 40 to 70. The research results showed that 17% of patients complained of "burning mouth": 10.2% of them had these symptoms due to oral mucosa diseases; 58.0% had glossodynia, 27.4% had discomfort because of intolerance to metal prosthodontic materials and 4.4% had combined pathology. Glossodynia and intolerance to metal prosthodontic materials had much in common in terms of clinical features, but the last one may be specified by changes in saliva composition. BMS thus proved to be the common definition corresponding to various diseases of oral mucosa and intolerance to intraoral metal appliances, while glossoldynia is a distinct neurogenic disease which is difficult to treat and requires comprehensive approach involving neurologist and physician.


Assuntos
Síndrome da Ardência Bucal/diagnóstico , Síndrome da Ardência Bucal/psicologia , Glossalgia/diagnóstico , Saliva/química , Adulto , Idoso , Síndrome da Ardência Bucal/classificação , Diagnóstico Diferencial , Feminino , Glossalgia/classificação , Humanos , Masculino , Pessoa de Meia-Idade
12.
Orthod Fr ; 85(3): 287-97, 2014 Sep.
Artigo em Francês | MEDLINE | ID: mdl-25158751

RESUMO

Hypnosis is making a comeback in all of the medical disciplines. But in a world where everyone wants to control everything and manage everything, it's helpful to know that hypnosis is a dynamic process that cannot be forced on anyone, a psychic reality, clearly demonstrated today by brain imaging. Hypnosis does not take any power over the individual. It is just one more tool to help ease patient's discomfort. It is also useful to avoid professional burnout to provide care without depleting our energy and without wasting our valuable time. Medical hypnosis is a real asset for providing comfortable orthodontic treatment and creating a serene atmosphere. It can be done simply and rapidly to take high quality impressions, to place braces comfortably on a patient who is sitting quietly. Orthodontic treatment requires cooperation and motivation, so let's give our patients a new sense of confidence and a willingness to cooperate.


Assuntos
Hipnose em Odontologia , Ortodontia Corretiva , Transtornos da Articulação/prevenção & controle , Bruxismo/prevenção & controle , Comunicação , Comportamento Cooperativo , Ansiedade ao Tratamento Odontológico/prevenção & controle , Colagem Dentária/métodos , Técnica de Moldagem Odontológica , Relações Dentista-Paciente , Glossalgia/prevenção & controle , Humanos , Idioma , Motivação , Higiene Bucal , Aparelhos Ortodônticos , Dor/prevenção & controle , Autoimagem , Pensamento
13.
Ter Arkh ; 86(1): 107-10, 2014.
Artigo em Russo | MEDLINE | ID: mdl-24757710

RESUMO

Burning mouth syndrome (glossalgia) is manifested by oral pin and tingling sensations, numbness and even burning and severe pains, more frequently in the tongue. Unpleasant sensations may involve the anterior two thirds of the tongue or be extended to the front part of the hard palate and the mucous membrane of the lower lip. This condition is characterized by "mirror" and "food dominant" symptoms, disordered salivation, dysgeusia, or psychological disorders. The disease shows a chronic course. Its etiology may be multifactorial. There are no universally accepted diagnostic criteria; the diagnosis of glossalgia is made to rule out all other causes. A thorough examination should be conducted to establish a differential diagnosis. Glossalgia occurs primarily in middle-aged and elderly people. Women get sick much more frequently than men of the same age. Glossalgia remains difficult to treat. Continuous symptomatic treatment and follow-up help relieve its symptoms.


Assuntos
Glossalgia/diagnóstico , Fatores Etários , Diagnóstico Diferencial , Saúde Global , Glossalgia/epidemiologia , Humanos , Incidência , Fatores Sexuais , Síndrome
15.
J Oral Pathol Med ; 43(2): 111-6, 2014 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-23869755

RESUMO

OBJECTIVE: The aim of this study was to investigate salivary markers related to burning mouth syndrome (BMS). STUDY DESIGN: A cross-sectional prospective controlled clinical study of 58 patients (28 BMS and 30 control). The presence of mineral and trace metals in unstimulated whole saliva was analyzed in BMS patients and in control subjects by means of ICP-OES. The parameters analyzed were as follows: oral health-related quality of life (OHIP-14) and the Hospital Anxiety Depression (HAD) scale. A visual analogue scale (VAS) was used to measure the intensity of burning sensation (pain). RESULTS: The mean pain value for patients with BMS was 7.8 ± 2.4. OHIP-14 oral health-related quality of life among BMS patients was found to be affected: total BMS OHIP-14 (16.98 ± 12.29) vs. control (8.53 ± 10.5) with significant difference (P = 0.015). Concentrations of the different elements were slightly higher among BMS patients but without statistically significant differences for any of the elements analyzed (Na, K, Ca, Mg, Fe, Cu, Mn, Zn, B, P, S, Al, Pb, Cd, Cr, Ni, As, Be, Bi, Co, Li, Mo, Sb, Se, Sr, Ti, Tl, V). CONCLUSIONS: This study failed to identify abnormal levels of minerals or trace elements in saliva of patients with BMS.


Assuntos
Síndrome da Ardência Bucal/metabolismo , Minerais/análise , Saliva/química , Oligoelementos/análise , Adulto , Idoso , Idoso de 80 Anos ou mais , Ansiedade/psicologia , Síndrome da Ardência Bucal/psicologia , Estudos de Casos e Controles , Estudos Transversais , Depressão/psicologia , Feminino , Glossalgia/psicologia , Humanos , Masculino , Pessoa de Meia-Idade , Saúde Bucal , Medição da Dor/métodos , Estudos Prospectivos , Qualidade de Vida , Análise Espectral , Escala Visual Analógica
16.
Psychogeriatrics ; 13(2): 99-102, 2013 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-23909967

RESUMO

Glossodynia is chronic pain localized around the tongue, with no perceivable organic abnormalities. In the fields of oral and maxillofacial surgery, it is categorized as an oral psychosomatic disease. In contrast, psychiatric nosology classifies glossodynia as a pain disorder among somatoform disorders, per the DSM-IV. The patient was a 71-year-old woman who developed symptoms of glossodynia, specifically a sore tongue. In the decade before she presented to us, she had had bizarre symptoms of oral cenesthopathy such as the sensation that her teeth had become 'limp and floppy' and that she needles in her mouth. Treatment was attempted using several psychotropic drugs, but no satisfactory response was noted. Because the patient was referred to our outpatient clinic, we tried psychotropic therapy again. Additionally, valproic acid, tandospirone and sertraline were administered (in this order), but the patient still showed no response. However, when sertraline was changed to milnacipran, all symptoms disappeared in a short period. We suggest that a small dose of milnacipran can be effective for controlling oral cenesthopathy as well as glossodynia.


Assuntos
Síndrome da Ardência Bucal/tratamento farmacológico , Ciclopropanos/administração & dosagem , Glossalgia/tratamento farmacológico , Esquizofrenia Paranoide/complicações , Transtornos Somatoformes/tratamento farmacológico , Síndrome da Ardência Bucal/diagnóstico , Síndrome da Ardência Bucal/psicologia , Relação Dose-Resposta a Droga , Feminino , Glossalgia/complicações , Glossalgia/etiologia , Humanos , Milnaciprano , Esquizofrenia Paranoide/tratamento farmacológico , Transtornos Somatoformes/etiologia , Resultado do Tratamento
17.
Dent Clin North Am ; 57(3): 497-512, 2013 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-23809306

RESUMO

Burning mouth syndrome (BMS) is a chronic condition that is characterized by burning symptoms of the oral mucosa without obvious clinical examination findings. This syndrome has complex characteristics, but its cause remains largely enigmatic, making treatment and management of patients with BMS difficult. Despite not being accompanied by evident organic changes, BMS can significantly reduce the quality of life for such patients. Therefore, it is incumbent on dental professionals to diagnose and manage patients with BMS as a part of comprehensive care.


Assuntos
Síndrome da Ardência Bucal , Dor Facial/etiologia , Síndrome da Ardência Bucal/complicações , Síndrome da Ardência Bucal/diagnóstico , Síndrome da Ardência Bucal/tratamento farmacológico , Síndrome da Ardência Bucal/etiologia , Diagnóstico Diferencial , Glossalgia/etiologia , Humanos , Mucosa Bucal/patologia , Qualidade de Vida
19.
J Oral Sci ; 55(1): 17-22, 2013 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-23485596

RESUMO

This study was conducted to assess the psychological characteristics of, and determine the effectiveness of group cognitive-behavioral (CB) treatment for, patients with burning mouth syndrome (BMS). The baseline characteristics of 24 female patients (age 69.7 ± 5.9 years) and an identical number of healthy female control subjects (age 69.2 ± 5.5 years) were compared. The patient group had significantly higher anxiety scores (P < 0.05) at baseline. A brief group CB intervention was delivered in a small-group format. Two sessions were planned 6 months apart. A numeric rating scale (NRS) was used to assess pain intensity. Anxiety was evaluated using a state and trait anxiety inventories. Present pain intensity decreased after both the first and second sessions. The session effect was significant (P = 0.02), but no repeat effect was found (P = 0.19). The state anxiety inventory score also decreased after the second session. The session effect was significant (P < 0.01), as was the repeat effect (P < 0.01). The trait anxiety inventory score decreased after the second session, and the session effect was significant (P = 0.013), but the repeat effect was not (P = 0.93). The results suggest that a brief group CB intervention reduces pain intensity and anxiety in patients with BMS.


Assuntos
Síndrome da Ardência Bucal/terapia , Terapia Cognitivo-Comportamental , Glossalgia/terapia , Psicoterapia de Grupo , Atividades Cotidianas , Idoso , Ansiedade/psicologia , Síndrome da Ardência Bucal/psicologia , Estudos de Casos e Controles , Feminino , Glossalgia/psicologia , Humanos , Medição da Dor , Inventário de Personalidade , Psicoterapia Breve , Terapia de Relaxamento
20.
BMJ Case Rep ; 20122012 Nov 19.
Artigo em Inglês | MEDLINE | ID: mdl-23166175

RESUMO

Spontaneous glossodynia is uncommon and glossodynia progressing to necrosis is especially rare. Although the commonest cause of lingual necrosis is giant cell arteritis, only a few cases of a new diagnosis of giant cell arteritis, clinically presenting with isolated lingual necrosis, have been reported.


Assuntos
Arterite de Células Gigantes/diagnóstico , Língua/patologia , Idoso , Desbridamento , Diagnóstico Diferencial , Progressão da Doença , Feminino , Arterite de Células Gigantes/cirurgia , Glossalgia/etiologia , Humanos , Necrose , Língua/cirurgia
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA