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1.
Environ Monit Assess ; 192(8): 548, 2020 Jul 28.
Artigo em Inglês | MEDLINE | ID: mdl-32720051

RESUMO

This paper aims to determine the potential for using medicinal aromatic plants, which have been considered living heritage since prehistoric times, in urban landscapes. The area of study covers Malatya City and its counties, which are found in Eastern Anatolia, a region of importance in terms of the endemic species in Turkey. Malatya is specifically selected as the study area, as the city's geomorphological, hydrological and climatic characteristics favour a high floral diversity. The methods used in this paper consist of five stages: floristic field works conducted in Battalgazi county (Malatya) in the scope of the Scientific and Technological Research Council of Turkey (TUBITAK) Project No. 217O290, the identification of the plants by a taxonomist, the determination of the medicinal and aromatic species in other counties of Malatya based on literature review, the establishment of criteria for the application potential of the identified species in landscape designs and the assessment of the use of the identified species in landscape architecture according to the parameters set in the criteria. Aromatic medicinal species were analysed to generate planting designs in landscape projects; the aesthetic properties (flower, leaf and fruit characteristics), sensory properties (scent and texture), seasonal change characteristics (flowering period and colour change) and use areas (flower parterres, solitary plantings, live fences and site coverings) of the plants were analysed. As a result of ethnobotanical and floristic studies carried out within the boundaries of the study area, a total of 189 medical aromatic species were identified. A total of 157 of these species were herbaceous plants. In conclusion, it was determined that 80 aromatic medicinal species conform to the planting design criteria and could be used in landscape designs in Malatya City.


Assuntos
Medicina Tradicional , Plantas Medicinais , Monitoramento Ambiental , Etnobotânica , Turquia
2.
Medicine (Baltimore) ; 99(27): e21074, 2020 Jul 02.
Artigo em Inglês | MEDLINE | ID: mdl-32629739

RESUMO

BACKGROUND: Diagnosis of thoracic outlet syndrome (TOS) is challenging; however, proper evaluation and treatment ensure relief from symptoms in most patients. A comprehensive approach to treatment is important, considering the multifactorial etiology of TOS. The objective of this systematic review is to describe the methods for evaluating the effectiveness and safety of acupuncture-based traditional medicine treatments for TOS. METHODS: A total of 13 databases will be searched, from their inception to the present date, for studies that have investigated the treatment of TOS. Databases that will be included are MEDLINE, Embase, AMED, Cochrane Library, CINAHL, and 4 Korean, 2 Chinese, and 2 Japanese databases.We will include randomized controlled trials (RCTs) assessing acupuncture-based traditional medicine for the treatment of any type of TOS. All RCTs on traditional medicine with any form of acupuncture will be eligible for inclusion. The methodologic quality of the RCTs will be analyzed using the Cochrane Collaboration tool to assess the risk of bias, and the confidence in the cumulative evidence will be assessed using the grading of recommendations assessment, development, and evaluation instrument. ETHICS AND DISSEMINATION: The results of this systematic review will be published in a peer-reviewed journal and disseminated both electronically and in print. The review will be updated to inform and guide health care practices. TRIAL REGISTRATION NUMBER: PROSPERO 2020 CRD42020164869.


Assuntos
Terapia por Acupuntura/métodos , Medicina Tradicional/métodos , Síndrome do Desfiladeiro Torácico/terapia , Bases de Dados Factuais , Feminino , Humanos , Incidência , Masculino , Medicina Tradicional Chinesa , Medicina Tradicional Coreana , Medicina Tradicional/tendências , Ensaios Clínicos Controlados Aleatórios como Assunto , Segurança , Síndrome do Desfiladeiro Torácico/epidemiologia , Resultado do Tratamento
3.
Acta Med Hist Adriat ; 18(1): 15-26, 2020 06.
Artigo em Inglês | MEDLINE | ID: mdl-32638597

RESUMO

The heritage of Slovenian house names and surnames reflects, among others, the former medicine and pharmaceutical occupations, midwifery, and folk medicine practices, and besides that, also health status and illnesses of people. Surnames, which are especially strongly intertwined with family, local and social history, are closely related to folk medicine and magic. Unlike house names (vulgo), which are the usual nicknames for physical and mental characteristics and abilities, surnames denote medical occupations and medicinal folk practice as such. According to the most recent data (as of January 1, 2020) of The Statistical Office of the Republic of Slovenia, at least 40 surnames reminiscent former medical or pharmaceutical professions. These newly discovered digital data in open access are precious for the history of medicine because they allow comparing surnames geographically, by frequency, and through the time.


Assuntos
História da Medicina , História da Farmácia , Nomes , Médicos/história , Animais , Educação Médica/história , História do Século XVI , História do Século XVII , História do Século XVIII , História do Século XIX , Humanos , Medicina Tradicional/história , Eslovênia
4.
Acta Med Hist Adriat ; 18(1): 89-104, 2020 06.
Artigo em Servo-Croata (Latino) | MEDLINE | ID: mdl-32638601

RESUMO

The paper presents a folk recipe collection manuscript written by an unknown author in Poljica area, in the 18th century. It is owned by the philologist, historian of literature and bibliophile, Josip Bratulic. Therefore, the author suggests that this recipe collection should bear the name Great folk medicine book from Poljica (Bratulic's folk medicine book). The manuscript is written in Latin script and Croatian language. It consists of 288 pages written in black ink and contains more than 1,100 recipes making it one of the largest known manuscripts. Although well preserved, a small part of it is unreadable. Most recommended recipes are for treating humans and domestic animals, while several recipes contain household tips. The abundance of its content, expressions, and healing instructions add this recipe collection to other similar manuscripts of this region, which create precious part of the Croatian medical, pharmaceutical, and cultural heritage.


Assuntos
Manuscritos Médicos como Assunto/história , Medicina Tradicional/história , Farmacopeias como Assunto/história , Croácia , História do Século XVIII
6.
Zhongguo Zhong Yao Za Zhi ; 45(10): 2265-2274, 2020 May.
Artigo em Chinês | MEDLINE | ID: mdl-32495579

RESUMO

In December 2019, an outbreak of viral pneumonia began in Wuhan, Hubei Province, which caused the spread of infectious pneumonia to a certain extent in China and neighboring countries and regions, and triggered the epidemic crisis. The coronavirus disease 2019(COVID-19) is an acute respiratory infectious disease listed as a B infectious disease, which is managed according to standards for A infectious disease. Traditional Chinese medicine and integrated traditional Chinese and Western medicine have played an active role in the prevention and control of this epidemic. China's ethnomedicine has recognized infectious diseases since ancient times, and formed a medical system including theory, therapies, formula and herbal medicines for such diseases. Since the outbreak of the COVID-19 epidemic, Tibet Autonomous Region, Qinghai Province, Inner Mongolia Autonomous Region, Xinjiang Uygur Autonomous Region and Chuxiong Autonomous Prefecture of Yunnan, Qiandongnan Autonomous Prefecture of Guizhou have issued the prevention and control programs for COVID-19 using Tibetan, Mongolian, Uygur, Yi and Miao medicines. These programs reflect the wisdom of ethnomedicine in preventing and treating diseases, which have successfully extracted prescriptions and preventive measures for the outbreak of the epidemic from their own medical theories and traditional experiences. In this paper, we summarized and explained the prescriptions and medicinal materials of ethnomedicine in these programs, and the origin of Tibetan medicine prescriptions and Mongolian medicine prescriptions in ancient books were studied. These become the common characteristics of medical prevention and treatment programs for ethnomedicine to formulate therapeutic programs under the guidance of traditional medicine theories, recommend prescriptions and prevention and treatment methods with characteristics of ethnomedicine, and focus on the conve-nience and standardization. However, strengthening the support of science and technology and the popularization to the public, and improving the participation of ethnomedicine in national public health services and the capacity-building to deal with sudden and critical diseases are key contents in the development of ethnomedicine in the future.


Assuntos
Betacoronavirus , Infecções por Coronavirus/tratamento farmacológico , Pneumonia Viral/tratamento farmacológico , China , Humanos , Medicina Tradicional , Pandemias , Tibet
7.
PLoS One ; 15(5): e0232288, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32379779

RESUMO

INTRODUCTION: Ethnobotanical studies that include participatory methods aim to engage residents in different steps to promote the strengthening and perpetuation of local culture, and empowerment in making decisions about the use of available environmental resources. Thus, the aim of this project was to perform an ethnobotanical survey based on traditional knowledge of medicinal plants with the active participation of residents living in Bairro do Cambury, Ubatuba, São Paulo State, Brazil. MATERIALS AND METHODS: During meetings held between the researchers and community members, locally used plants were regarded as an important means for preserving local knowledge for future generations. Some residents showed interest in participating as local partners, and training courses for collecting ethnobotanical data were offered. Local partners and researchers from São Paulo Federal University (Universidade Federal de São Paulo) utilized ethnobotanical methods to select and interview the specialists in medicinal plants for 80 days between 2016 and 2018. Data on plant use were recorded, and plants were collected and deposited in two herbaria. Furthermore, participant observation and fieldwork diaries were used by the researchers, aiding the data analysis. RESULTS: Three local partners participated in objective definitions, data collection, analysis and publication. Nine local specialists were interviewed by the local partners and indicated the use of 82 plant species in 90 recipes for 55 therapeutic uses. These uses were grouped into 12 categories. In addition, a video and booklet were created. CONCLUSIONS: Data obtained during participatory research show that training local communities in the registration of their own knowledge is feasible and necessary since they register knowledge based on local perceptions, as well as valuing knowledge and approaching the current discussion about intellectual property is a global concern.


Assuntos
Etnobotânica/métodos , Conhecimentos, Atitudes e Prática em Saúde/etnologia , Medicina Tradicional/métodos , Brasil/etnologia , Prova Pericial/métodos , Feminino , Humanos , Conhecimento , Masculino , Pessoa de Meia-Idade , Plantas Medicinais , Registros , Participação dos Interessados/psicologia , Inquéritos e Questionários
9.
Br J Nurs ; 29(7): 426-430, 2020 Apr 09.
Artigo em Inglês | MEDLINE | ID: mdl-32279559

RESUMO

BACKGROUND: Knowledge of traditional and complementary medicine (TCM) and its use by patients are essential for patient safety. AIMS: To examine knowledge of TCM among practitioners in a nephrology unit and their advice to patients. METHODS: This was a descriptive, observational, cross-sectional study. Sociodemographic data were collected and an ad hoc closed response survey was used. FINDINGS: This study included 62 practitioners, of whom: 32.26% had been trained in TCM, with no significant differences between professional groups; 41.93% used TCM and 67.74% recommended TCM to patients, with no significant difference between personal use and training received. The majority (62.90%) approved of TCM being included in clinical practice, 77.42% were in favour of it being included in formal health teaching programmes, 27.42% said patients had requested information on TCM and 50% knew it could interact with conventional treatment. CONCLUSION: Although the majority of practitioners had not been trained in TCM, they were interested in including such treatments in clinical practice. They recommended TCM to patients, but neither training nor personal experience were significant factors in relation to these recommendations. Training in TCM is required to ensure advice is safe.


Assuntos
Terapias Complementares , Conhecimentos, Atitudes e Prática em Saúde , Medicina Tradicional , Nefrologia , Recursos Humanos em Hospital/psicologia , Adulto , Estudos Transversais , Feminino , Departamentos Hospitalares , Hospitais Universitários , Humanos , Masculino , Pessoa de Meia-Idade , Recursos Humanos em Hospital/estatística & dados numéricos , Espanha
10.
N Z Med J ; 133(1513): 73-80, 2020 04 24.
Artigo em Inglês | MEDLINE | ID: mdl-32325470

RESUMO

BACKGROUND: Rongoa Maori is the traditional form of healing for Maori. This investigation describes the results of an internet-based survey of staff at Waitemata District Health Board (WDHB) about their attitudes towards the placement of Rongoa Maori into the hospital system. METHODS: An electronic survey was circulated to approximately 6,000 employees of the WDHB. Responders were asked questions pertaining to Rongoa Maori and issues relating to potential implementation of a Rongoa Maori service. RESULTS: There were 1,181 responses (response rate 19.6%) of whom 80% were female, 87% aged between 20 and 60 years, 67% European ethnicity, 18% Maori and 66% worked as medical practitioners or nurses. Forty-six percent were familiar with Rongoa Maori, and 16% had used Rongoa Maori on themselves or whanau. About 32% of responders felt that Rongoa Maori should be available to patients and staff and that this service should be provided by a specially trained Rongoa Maori practitioners or WDHB staff member. CONCLUSION: Nearly half of WDHB staff, who responded to the survey, had a knowledge of Rongoa Maori and just over a third of the total responders supported its availability within the hospital system. A larger feasibility study will consult with healer, staff and patient participants to ascertain the culturally appropriate and medically robust practices necessary for researching Rongoa Maori collaboration with medical treatment.


Assuntos
Atitude do Pessoal de Saúde , Pessoal de Saúde/estatística & dados numéricos , Hospitais Públicos , Medicina Tradicional , Adulto , Assistência à Saúde , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Grupo com Ancestrais Oceânicos , Inquéritos e Questionários , Adulto Jovem
11.
J Ethnobiol Ethnomed ; 16(1): 19, 2020 Apr 21.
Artigo em Inglês | MEDLINE | ID: mdl-32316979

RESUMO

The Journal of Ethnobiology and Ethnomedicine (JEET), throughout its 15 years of existence, has tried to provide a respected outlet for scientific knowledge concerning the inextricable links between human societies and nature, food, and health. Ethnobiology and ethnomedicine-centred research has moved at the (partially artificial and fictitious) interface between nature and culture and has investigated human consumption of wild foods and wild animals, as well as the use of wild animals or their parts for medicinal and other purposes, along with the associated knowledge, skills, practices, and beliefs. Little attention has been paid, however, to the complex interplay of social and cultural reasons behind the increasing pressure on wildlife. The available literature suggest that there are two main drivers that enhance the necessary conditions for infectious diseases to cross the species barrier from wild animals to humans: (1) the encroachment of human activities (e.g., logging, mining, agricultural expansion) into wild areas and forests and consequent ecological disruptions; and, connected to the former, (2) the commodification of wild animals (and natural resources in general) and an expanding demand and market for wild meat and live wild animals, particularly in tropical and sub-tropical areas. In particular, a crucial role may have been played by the bushmeat-euphoria and attached elitist gastronomies and conspicuous consumption phenomena. The COVID-19 pandemic will likely require ethnobiologists to reschedule research agendas and to envision new epistemological trajectories aimed at more effectively mitigating the mismanagement of natural resources that ultimately threats our and other beings' existence.


Assuntos
Infecções por Coronavirus , Pandemias , Pneumonia Viral , Animais , Animais Selvagens , Betacoronavirus , Infecções por Coronavirus/tratamento farmacológico , Infecções por Coronavirus/epidemiologia , Infecções por Coronavirus/transmissão , Humanos , Carne , Medicina Tradicional , Pneumonia Viral/tratamento farmacológico , Pneumonia Viral/epidemiologia , Pneumonia Viral/transmissão
12.
Food Chem ; 317: 126411, 2020 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-32087517

RESUMO

Widely used throughout the world as traditional medicine for treating a variety of diseases ranging from cancer to microbial infections, members of the Tradescantia genus show promise as sources of desirable bioactive compounds. The bioactivity of several noteworthy species has been well-documented in scientific literature, but with nearly seventy-five species, there remains much to explore in this genus. This review aims to discuss all the bioactivity-related studies of Tradescantia plants and the compounds discovered, including their anticancer, antimicrobial, antioxidant, and antidiabetic activities. Gaps in knowledge will also be identified for future research opportunities.


Assuntos
Plantas Medicinais/química , Tradescantia/química , Anti-Infecciosos/química , Anti-Infecciosos/farmacologia , Antineoplásicos Fitogênicos/química , Antineoplásicos Fitogênicos/farmacologia , Antioxidantes/química , Antioxidantes/farmacologia , Humanos , Hipoglicemiantes/química , Hipoglicemiantes/farmacologia , Medicina Tradicional
13.
Phytother Res ; 34(7): 1678-1686, 2020 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-32086985

RESUMO

Ageratina pichinchensis is utilized in traditional medicine for the treatment of dermatomycosis and inflammation. The aim of this study was to evaluate the clinical and mycological effectiveness of the topical administration of an enecalin standardized extract of A. pichinchensis for treating onychomycosis in patients with type 2 diabetes mellitus (DM2). A double blind, randomized, and controlled clinical trial was carried out that included patients with DM2 and who had mild or moderate onychomycosis. Participants were administered topically, for 6 months, a lacquer containing the encecalin standardized extract of A. pichinchensis (experimental group) or 8% ciclopirox (control group). In a large percentage of both, the control group (77.2%) and the experimental group (78.5%), clinical efficacy was detected as a decrease in the number of affected nails and a reduction in the severity of nail involvement. Without exhibiting statistically significant differences between groups, the encecalin standardized extract of A. pichinchensis was clinically and mycologically effective in the treatment of mild and moderate onychomycosis in patients with DM2. The treatment of onychomycosis in patients with DM2 implies a greater challenge, while control of blood glucose levels in these patients, played a very important role in the response of patients to treatment.


Assuntos
Ageratina/química , Diabetes Mellitus Tipo 2/complicações , Medicina Tradicional/métodos , Onicomicose/tratamento farmacológico , Fitoterapia/métodos , Extratos Vegetais/química , Diabetes Mellitus Tipo 2/tratamento farmacológico , Método Duplo-Cego , Feminino , Humanos , Masculino , Pessoa de Meia-Idade
14.
PLoS One ; 15(2): e0228529, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32027688

RESUMO

Postpartum care is a critical element for ensuring survival and health of mothers and newborns but is often inadequate in low- and middle-income countries due to barriers to access and resource constraints. Newly delivered mothers and their families often rely on traditional forms of postnatal care rooted in social and cultural customs or may blend modern and traditional forms of care. This ethnographic study sought to explore use of biomedical and traditional forms of postnatal care. Data were collected through unstructured observation and in-depth interviews with 15 mothers. Participants reported embracing traditional understandings of health and illness in the post-partum period centered on heating the body through diet, steaming, and other applications of heat, yet also seeking injections from private health care providers. Thematic analysis explored concepts related to transitioning forms of postnatal care, valuing of care through different lenses, and diverse sources of advice on postnatal care. Mothers also described concurrent use of both traditional medicine and biomedical postnatal care, and the importance of adhering to cultural traditions of postnatal care for future health. Maternal and newborn health are closely associated with postnatal care, so ensuring culturally appropriate and high-quality care must be an important priority for stakeholders including understand health practices that are evolving to include injections.


Assuntos
Antropologia Cultural , Temperatura Corporal/fisiologia , Temperatura Alta/uso terapêutico , Injeções , Medicina Tradicional/métodos , Cuidado Pós-Natal/métodos , Adulto , Camboja/epidemiologia , Feminino , Conhecimentos, Atitudes e Prática em Saúde , Humanos , Hipertermia Induzida/métodos , Hipertermia Induzida/psicologia , Hipertermia Induzida/estatística & dados numéricos , Saúde do Lactente , Recém-Nascido , Injeções/psicologia , Injeções/estatística & dados numéricos , Masculino , Medicina Tradicional/estatística & dados numéricos , Mães , Aceitação pelo Paciente de Cuidados de Saúde , Cuidado Pós-Natal/estatística & dados numéricos , Período Pós-Parto , Padrões de Prática Médica/estatística & dados numéricos , Gravidez , Inquéritos e Questionários
15.
PLoS One ; 15(1): e0227293, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31940375

RESUMO

BACKGROUND: Nepal has achieved a significant reduction of TB incidence over the past decades. Nevertheless, TB patients continue to experience barriers in access, diagnosis and completion of the treatment. The main objective of this study was to explore the factors affecting the access to the health services, diagnosis and the treatment completion for TB patients in central and western Nepal. METHODS: Data were collected using in-depth interviews (IDI) with the TB patients (n = 4); Focus Group Discussions (FGDs) with TB suspected patients (n = 16); Semi Strucutred Interviews (SSIs) with health workers (n = 24) and traditional healers (n = 2); and FGDs with community members (n = 8). All data were audio recorded, transcribed and translated to English. All transcriptions underwent thematic analysis using qualitative data analysis software: Atlas.ti. RESULTS: Barriers to access to the health centre were the long distance, poor road conditions, and costs associated with travelling. In addition, lack of awareness of TB and its consequences, and the belief, prompted many respondents to visit traditional healers. Early diagnosis of TB was hindered by lack of trained health personnel to use the equipment, lack of equipment and irregular presence of health workers. Additional barriers that impeded the adherence and treatment completion were the need to visit health centre daily for DOTS treatment and associated constraints, complex treatment regimen, and the stigma. CONCLUSIONS: Barriers embedded in health services and care seekers' characteristics can be dealt by strengthening the peripheral health services. A continuous availability of (trained) human resources and equipment for diagnosis is critical. As well as increasing the awareness and collaborating with the traditional healers, health services utilization can be enhanced by compensating the costs associated with it, including the modification in current DOTS strategy by providing medicine for a longer term under the supervision of a family member, peer or a community volunteer.


Assuntos
Grupos Focais , Acesso aos Serviços de Saúde/organização & administração , Colaboração Intersetorial , Medicina Tradicional , Tuberculose/terapia , Adulto , Participação da Comunidade , Família , Feminino , Conhecimentos, Atitudes e Prática em Saúde , Pessoal de Saúde/estatística & dados numéricos , Acesso aos Serviços de Saúde/estatística & dados numéricos , Humanos , Masculino , Pessoa de Meia-Idade , Nepal , Aceitação pelo Paciente de Cuidados de Saúde/psicologia , Pesquisa Qualitativa , Estigma Social , Inquéritos e Questionários/estatística & dados numéricos , Tuberculose/diagnóstico , Tuberculose/psicologia , Adulto Jovem
16.
Phytother Res ; 34(2): 315-328, 2020 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-31713286

RESUMO

Convolvulus genus is a representative of the family of Convolvulaceae. Convolvulus plants are broadly distributed all over the world and has been used for many centuries as herbal medicine. Convolvulus genus contains various phytochemicals such as flavonoids, alkaloids, carbohydrates, phenolic compounds, mucilage, unsaturated sterols or terpenes, resin, tannins, lactones, and proteins. This review highlights the phytochemical composition, antimicrobial and antioxidant activities, application as food preservative, traditional medicine use, anticancer activities, and clinical effectiveness in human of Convolvulus plants. All the parts of Convolvulus plants possess therapeutic benefits; preliminary pharmacological data validated their use in traditional medicine. However, further preclinical and clinical experiments are warranted before any application in human health.


Assuntos
Convolvulus/química , Compostos Fitoquímicos/farmacologia , Extratos Vegetais/farmacologia , Plantas Medicinais/química , Animais , Anti-Infecciosos/farmacologia , Antineoplásicos Fitogênicos/farmacologia , Antioxidantes/farmacologia , Convolvulus/classificação , Conservantes de Alimentos , Humanos , Medicina Tradicional , Fitoterapia , Plantas Medicinais/classificação
17.
J Chromatogr A ; 1609: 460501, 2020 Jan 04.
Artigo em Inglês | MEDLINE | ID: mdl-31515074

RESUMO

Natural products (NPs) and traditional medicines (TMs) are used for treatment of various diseases and also to develop new drugs. However, identification of drug leads within the immense biodiversity of living organisms is a challenging task that requires considerable time, labor, and computational resources as well as the application of modern analytical instruments. LC-MS platforms are widely used for both drug discovery and quality control of TMs and food supplements. Moreover, a large dataset generated during LC-MS analysis contains valuable information that could be extracted and handled by means of various data mining and statistical tools. Novel sophisticated LC-MS based approaches are being introduced every year. Therefore, this review is prepared for the scientists specialized in pharmacognosy and analytical chemistry of NPs as well as working in related areas, in order to navigate them in the world of diverse LC-MS based techniques and strategies currently employed for NP discovery and dereplication, quality control, pattern recognition and sample comparison, and also in targeted and untargeted metabolomic studies. The suggested classification system includes the following LC-MS based procedures: elemental composition determination, isotopic fine structure analysis, mass defect filtering, de novo identification, clustering of the compounds in Molecular Networking (MN), diagnostic fragment ion (or neutral loss) filtering, manual dereplication using MS/MS data, database-assisted peak annotation, annotation of spectral trees, MS fingerprinting, feature extraction, bucketing of LC-MS data, peak profiling, predicted metabolite screening, targeted quantification of biomarkers, quantitative analysis of multi-component system, construction of chemical fingerprints, multi-targeted and untargeted metabolite profiling.


Assuntos
Cromatografia Líquida/métodos , Medicina Tradicional/normas , Espectrometria de Massas em Tandem/métodos , Produtos Biológicos/química , Humanos , Controle de Qualidade
18.
Phytother Res ; 34(1): 33-50, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31496018

RESUMO

The aim of this review is to collect together the results of the numerous studies over the last two decades on the pharmacological properties of palmatine published in scientific databases like Scopus and PubMed, which are scattered across different publications. Palmatine, an isoquinoline alkaloid from the class of protoberberines, is a yellow compound present in the extracts from different representatives of Berberidaceae, Papaveraceae, Ranunculaceae, and Menispermaceae. It has been extensively used in traditional medicine of Asia in the treatment of jaundice, liver-related diseases, hypertension, inflammation, and dysentery. New findings describe its possible applications in the treatment of civilization diseases like central nervous system-related problems. This review intends to let this alkaloid come out from the shade of a more frequently described alkaloid: berberine. The toxicity, pharmacokinetics, and biological activities of this protoberberine alkaloid will be developed in this work.


Assuntos
Berberidaceae/química , Alcaloides de Berberina/farmacocinética , Alcaloides de Berberina/uso terapêutico , Medicina Tradicional/métodos , Animais , Modelos Animais de Doenças , Cães , Humanos , Ratos
19.
Nat Prod Res ; 34(4): 541-544, 2020 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-30362366

RESUMO

The rhizomes of Bergenia ciliata (B. ciliata, Family: Saxifragaceae) are widely used for treating gastric ulcers in folk medicine in Asia. It was hypothesized that anti-ulcer activity of B. ciliata is due to its anti-Helicobacter pylori (H. pylori) activity. The anti-H. pylori activity was investigated on six clinical bacterial isolates using agar well-diffusion and broth micro-dilution methods. The anti-H. pylori activity of amoxicillin (standard) was the highest (Zone of inhibition; ZI = 25 mm, minimum inhibitory concentration; MIC=0.125 µg/µL) whereas among all the extracts of the rhizomes, methanol extract showed the highest activity (ZI = 16 mm, MIC = 12.50 µg/µL). Bioassay guided isolation of methanol extract using chromatographic and crystallization techniques isolated bergenin (ZI = 21mm, MIC = 0.391µg/µL) as constituent responsible for anti-H. pylori activity. The present study describes for the first time anti-H. pylori activity and possible mechanism of anti-ulcer properties of rhizomes of B. ciliata.


Assuntos
Benzopiranos/isolamento & purificação , Helicobacter pylori/efeitos dos fármacos , Rizoma , Saxifragaceae/química , Úlcera/tratamento farmacológico , Antibacterianos/isolamento & purificação , Antibacterianos/farmacologia , Ásia , Benzopiranos/uso terapêutico , Humanos , Medicina Tradicional , Testes de Sensibilidade Microbiana , Extratos Vegetais/química , Extratos Vegetais/farmacologia , Úlcera Gástrica/tratamento farmacológico
20.
Int Clin Psychopharmacol ; 35(1): 1-7, 2020 01.
Artigo em Inglês | MEDLINE | ID: mdl-31361653

RESUMO

Traditional medicines in the form of health food and supplements are highly popular nowadays. They are often aggressively promoted with unsubstantiated health benefit claims. Patients suffering from chronic illness, such as psychiatric disorders may be attracted to these products and use them concurrently with their prescribed drugs. The potential danger of these health supplements and traditional medicines containing products have prompted repeated warnings by the US Food and Drug Administration in recent years. A new initiative by the Food and Drug Administration in 2019 was also implemented to strengthen the oversight of these supplements. The WHO global compendium will include traditional medicines in 2019, which has generated much debate about their safety. Many practising psychiatrists are not familiar with traditional medicines, and clinically useful information is also not easily available. In this review, we examine the nature and safety of commonly encountered traditional medicine in these health food products and supplements.


Assuntos
Suplementos Nutricionais , Medicina Tradicional/métodos , Minerais/uso terapêutico , Preparações de Plantas/uso terapêutico , Psiquiatria/métodos , Interações Medicamentosas , Humanos , Medicina Tradicional/efeitos adversos , Minerais/administração & dosagem , Preparações de Plantas/administração & dosagem , Preparações de Plantas/efeitos adversos , Estados Unidos , United States Food and Drug Administration/normas , Organização Mundial da Saúde
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