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1.
Nat Commun ; 11(1): 3823, 2020 07 30.
Artigo em Inglês | MEDLINE | ID: mdl-32732934

RESUMO

An accurate extraction of physiological and physical signals from human skin is crucial for health monitoring, disease prevention, and treatment. Recent advances in wearable bioelectronics directly embedded to the epidermal surface are a promising solution for future epidermal sensing. However, the existing wearable bioelectronics are susceptible to motion artifacts as they lack proper adhesion and conformal interfacing with the skin during motion. Here, we present ultra-conformal, customizable, and deformable drawn-on-skin electronics, which is robust to motion due to strong adhesion and ultra-conformality of the electronic inks drawn directly on skin. Electronic inks, including conductors, semiconductors, and dielectrics, are drawn on-demand in a freeform manner to develop devices, such as transistors, strain sensors, temperature sensors, heaters, skin hydration sensors, and electrophysiological sensors. Electrophysiological signal monitoring during motion shows drawn-on-skin electronics' immunity to motion artifacts. Additionally, electrical stimulation based on drawn-on-skin electronics demonstrates accelerated healing of skin wounds.


Assuntos
Monitorização Fisiológica/instrumentação , Sistemas Automatizados de Assistência Junto ao Leito , Pele/fisiopatologia , Dispositivos Eletrônicos Vestíveis , Artefatos , Estimulação Elétrica , Epiderme/fisiologia , Humanos , Movimento (Física) , Semicondutores , Auxiliares Sensoriais , Pele/lesões , Cicatrização
2.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi ; 37(4): 596-601, 2020 Aug 25.
Artigo em Chinês | MEDLINE | ID: mdl-32840075

RESUMO

With the rapid improvement of the perception and computing capacity of mobile devices such as smart phones, human activity recognition using mobile devices as the carrier has been a new research hot-spot. The inertial information collected by the acceleration sensor in the smart mobile device is used for human activity recognition. Compared with the common computer vision recognition, it has the following advantages: convenience, low cost, and better reflection of the essence of human motion. Based on the WISDM data set collected by smart phones, the inertial navigation information and the deep learning algorithm-convolutional neural network (CNN) were adopted to build a human activity recognition model in this paper. The K nearest neighbor algorithm (KNN) and the random forest algorithm were compared with the CNN network in the recognition accuracy to evaluate the performance of the CNN network. The classification accuracy of CNN model reached 92.73%, which was much higher than KNN and random forest. Experimental results show that the CNN algorithm model can achieve more accurate human activity recognition and has broad application prospects in predicting and promoting human health.


Assuntos
Algoritmos , Redes Neurais de Computação , Análise por Conglomerados , Atividades Humanas , Humanos , Movimento (Física)
3.
Head Face Med ; 16(1): 15, 2020 Jul 18.
Artigo em Inglês | MEDLINE | ID: mdl-32682430

RESUMO

BACKGROUND: To investigate the prognostic value of a three-dimensional dynamic quantitative analysis system to measure facial motion (3D ASFM) in acute facial palsy patients and compare it with subjective grading methods and electroneurography. METHODS: We continuously recruited 37 patients with acute (< 1 month) Bell's palsy. An integrated evaluation of facial palsy was performed for each patient. The integrated evaluation included the House-Brackmann grading system (H-BGS), Sunnybrook Facial Grading System (SFGS), electroneurography and three-dimensional objective measurements. Then, the entire set of evaluations were repeated for each patient 1 month later. The patients were followed up monthly until recovery or for up to more than 6 months. We adopted the SFGS and H-BGS as the representative subjective grading system and final criteria for recovery. Poor recovery was defined as an SFGS score less than 70 or H-BGS score higher than II. RESULTS: Multiple regression analysis was performed to find the best prognostic indicators. In less than 1 month from onset, ENoG had the highest prognostic value. However, in the second month from onset, the results of SFGS and 3D ASFM were identified as the best prognostic parameters, and a prediction formula with a determination coefficient of 0.673 was established. The receiver operating characteristic curves revealed that a gross score of the 3D ASFM less than 31 in the first evaluation and 49 in the second evaluation had higher sensitivity and specificity to predict poor recovery. CONCLUSIONS: In different phases of Bell's palsy, the best predictor of prognosis is different. ENOG is the most effective predictor of the prognosis in the first month after onset. In the second month after onset, the combination of SFGS and 3D ADSM is considered to be the best prognostic predictor.


Assuntos
Paralisia de Bell , Paralisia Facial , Face , Paralisia Facial/diagnóstico , Humanos , Masculino , Movimento (Física) , Prognóstico , Curva ROC
4.
Sensors (Basel) ; 20(12)2020 Jun 23.
Artigo em Inglês | MEDLINE | ID: mdl-32585864

RESUMO

The role of mobile robots for cleaning and sanitation purposes is increasing worldwide. Disinfection and hygiene are two integral parts of any safe indoor environment, and these factors become more critical in COVID-19-like pandemic situations. Door handles are highly sensitive contact points that are prone to be contamination. Automation of the door-handle cleaning task is not only important for ensuring safety, but also to improve efficiency. This work proposes an AI-enabled framework for automating cleaning tasks through a Human Support Robot (HSR). The overall cleaning process involves mobile base motion, door-handle detection, and control of the HSR manipulator for the completion of the cleaning tasks. The detection part exploits a deep-learning technique to classify the image space, and provides a set of coordinates for the robot. The cooperative control between the spraying and wiping is developed in the Robotic Operating System. The control module uses the information obtained from the detection module to generate a task/operational space for the robot, along with evaluating the desired position to actuate the manipulators. The complete strategy is validated through numerical simulations, and experiments on a Toyota HSR platform.


Assuntos
Betacoronavirus , Infecções por Coronavirus/prevenção & controle , Desinfecção/instrumentação , Pandemias/prevenção & controle , Pneumonia Viral/prevenção & controle , Robótica/instrumentação , Algoritmos , Infecções por Coronavirus/transmissão , Infecções por Coronavirus/virologia , Aprendizado Profundo , Desinfecção/métodos , Desenho de Equipamento , Humanos , Manutenção , Movimento (Física) , Pneumonia Viral/transmissão , Pneumonia Viral/virologia , Robótica/métodos , Robótica/estatística & dados numéricos
5.
PLoS One ; 15(6): e0234341, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32530931

RESUMO

Some patients with a bileaflet mechanical heart valve (BMHV) show significant increases in the transvalvular pressure drop and abnormal leaflet motion due to a pannus (an abnormal fibrovascular tissue) formed on the ventricular side, even in the absence of physical contact between the pannus and leaflets. We investigate the effects of the pannus shape (circular or semi-circular ring), implantation location and height on the leaflet motion, flow structure and transvalvular pressure drop using numerical simulations. The valve model considered resembles a 25 mm masters HP valve. The mean systolic pressure drop is significantly increased with increasing pannus height, irrespective of its implantation orientation. Near the peak inflow rate, the flow behind the pannus becomes highly turbulent, and the transvalvular pressure drop is markedly increased by the pannus. At the end of valve opening and the start of valve closing, oscillatory motions of the leaflets occur due to periodic shedding of vortex rings behind the pannus, and their amplitudes become large with increasing pannus height. When the pannus shape is asymmetric (e.g., a semi-circular ring) and its height reaches about 0.1D (D (= 25 mm) is the diameter of an aorta), abnormal leaflet motions occur: two leaflets move asymmetrically, and valve closing is delayed in time or incomplete, which increases the regurgitation volume. The peak energy loss coefficients due to panni are obtained from simulation data and compared with those predicted by a one-dimensional model. The comparison indicates that the one-dimensional model is applicable for the BMHV with and without pannus.


Assuntos
Valva Aórtica/cirurgia , Próteses Valvulares Cardíacas/efeitos adversos , Modelos Cardiovasculares , Valva Aórtica/patologia , Valva Aórtica/fisiopatologia , Pressão Sanguínea/fisiologia , Simulação por Computador , Fibrose , Próteses Valvulares Cardíacas/estatística & dados numéricos , Hemodinâmica , Hemorreologia , Humanos , Movimento (Física) , Desenho de Prótese
6.
Proc Natl Acad Sci U S A ; 117(27): 16035-16042, 2020 07 07.
Artigo em Inglês | MEDLINE | ID: mdl-32571929

RESUMO

The mechanical principles for fast snapping in the iconic Venus flytrap are not yet fully understood. In this study, we obtained time-resolved strain distributions via three-dimensional digital image correlation (DIC) for the outer and inner trap-lobe surfaces throughout the closing motion. In combination with finite element models, the various possible contributions of the trap tissue layers were investigated with respect to the trap's movement behavior and the amount of strain required for snapping. Supported by in vivo experiments, we show that full trap turgescence is a mechanical-physiological prerequisite for successful (fast and geometrically correct) snapping, driven by differential tissue changes (swelling, shrinking, or no contribution). These are probably the result of the previous accumulation of internal hydrostatic pressure (prestress), which is released after trap triggering. Our research leads to an in-depth mechanical understanding of a complex plant movement incorporating various actuation principles.


Assuntos
Droseraceae/fisiologia , Movimento/fisiologia , Folhas de Planta/fisiologia , Fenômenos Biomecânicos , Simulação por Computador , Modelos Biológicos , Movimento (Física) , Fatores de Tempo , Gravação em Vídeo
8.
PLoS One ; 15(6): e0233441, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32502175

RESUMO

This paper employs a solution to the agent-guidance problem in an environment with obstacles, whose avoidance techniques have been extensively used in the last years. There is still a gap between the solution times required to obtain a trajectory and those demanded by real world applications. These usually face a tradeoff between the limited on-board processing performance and the high volume of computing operations demanded by those real-time applications. In this paper we propose a deferred decision-based technique that produces clusters used for obstacle avoidance as the agent moves in the environment, like a driver that, at night, enlightens the road ahead as her/his car moves along a highway. By considering the spatial and temporal relevance of each obstacle throughout the planning process and pruning areas that belong to the constrained domain, one may relieve the inherent computational burden of avoidance. This strategy reduces the number of operations required and increases it on demand, since a computationally heavier problem is tackled only if the simpler ones are not feasible. It consists in an improvement based solely on problem modeling, which, by example, may offer processing times in the same order of magnitude than the lower-bound given by the relaxed form of the problem.


Assuntos
Automação/métodos , Previsões/métodos , Aprendizagem da Esquiva/fisiologia , Simulação por Computador , Locomoção , Movimento (Física) , Programação Linear , Software
9.
Science ; 369(6499): 71-77, 2020 07 03.
Artigo em Inglês | MEDLINE | ID: mdl-32527924

RESUMO

Bacterial biofilms represent a basic form of multicellular organization that confers survival advantages to constituent cells. The sequential stages of cell ordering during biofilm development have been studied in the pathogen and model biofilm-former Vibrio cholerae It is unknown how spatial trajectories of individual cells and the collective motions of many cells drive biofilm expansion. We developed dual-view light-sheet microscopy to investigate the dynamics of biofilm development from a founder cell to a mature three-dimensional community. Tracking of individual cells revealed two distinct fates: one set of biofilm cells expanded ballistically outward, while the other became trapped at the substrate. A collective fountain-like flow transported cells to the biofilm front, bypassing members trapped at the substrate and facilitating lateral biofilm expansion. This collective flow pattern was quantitatively captured by a continuum model of biofilm growth against substrate friction. Coordinated cell movement required the matrix protein RbmA, without which cells expanded erratically. Thus, tracking cell lineages and trajectories in space and time revealed how multicellular structures form from a single founder cell.


Assuntos
Biofilmes , Vibrio cholerae/citologia , Vibrio cholerae/fisiologia , Proteínas de Bactérias/genética , Proteínas de Bactérias/metabolismo , Proteínas da Matriz Extracelular/genética , Proteínas da Matriz Extracelular/metabolismo , Microscopia , Movimento (Física) , Mutação , Análise de Célula Única/métodos , Vibrio cholerae/genética
10.
PLoS One ; 15(6): e0233209, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32497135

RESUMO

The impact of a method for MR-based respiratory motion correction of PET data on lesion visibility and quantification in patients with oncologic findings in the lung was evaluated. Twenty patients with one or more lesions in the lung were included. Hybrid imaging was performed on an integrated PET/MR system using 18F-FDG as radiotracer. The standard thoracic imaging protocol was extended by a free-breathing self-gated acquisition of MR data for motion modelling. PET data was acquired simultaneously in list-mode for 5-10 mins. One experienced radiologist and one experienced nuclear medicine specialist evaluated and compared the post-processed data in consensus regarding lesion visibility (scores 1-4, 4 being best), image noise levels (scores 1-3, 3 being lowest noise), SUVmean and SUVmax. Motion-corrected (MoCo) images were additionally compared with gated images. Non-motion-corrected free-breathing data served as standard of reference in this study. Motion correction generally improved lesion visibility (3.19 ± 0.63) and noise ratings (2.95 ± 0.22) compared to uncorrected (2.81 ± 0.66 and 2.95 ± 0.22, respectively) or gated PET data (2.47 ± 0.93 and 1.30 ± 0.47, respectively). Furthermore, SUVs (mean and max) were compared for all methods to estimate their respective impact on the quantification. Deviations of SUVmax were smallest between the uncorrected and the MoCo lesion data (average increase of 9.1% of MoCo SUVs), while SUVmean agreed best for gated and MoCo reconstructions (MoCo SUVs increased by 1.2%). The studied method for MR-based respiratory motion correction of PET data combines increased lesion sharpness and improved lesion activity quantification with high signal-to-noise ratio in a clinical setting. In particular, the detection of small lesions in moving organs such as the lung and liver may thus be facilitated. These advantages justify the extension of the PET/MR imaging protocol by 5-10 minutes for motion correction.


Assuntos
Artefatos , Processamento de Imagem Assistida por Computador/métodos , Neoplasias Pulmonares/diagnóstico por imagem , Pulmão/diagnóstico por imagem , Imagem por Ressonância Magnética/métodos , Movimento (Física) , Imagem Multimodal/métodos , Tomografia por Emissão de Pósitrons/métodos , Mecânica Respiratória , Idoso , Idoso de 80 Anos ou mais , Feminino , Radioisótopos de Flúor , Fluordesoxiglucose F18 , Humanos , Aumento da Imagem/métodos , Pulmão/fisiologia , Masculino , Pessoa de Meia-Idade , Compostos Radiofarmacêuticos
11.
Stud Health Technol Inform ; 270: 756-760, 2020 Jun 16.
Artigo em Inglês | MEDLINE | ID: mdl-32570484

RESUMO

This paper presents a convolutional neural network-based classification of the hand flexion and extension gestures used in wrist recovery after injury. The hand gesture recognition device used in our study is the Leap Motion controller. The Leap Motion device's inability to accurately differentiate the left hand from the right hand when performing hand rotation gestures was eliminated by introducing hand and thumb direction vectors into the database used to train the neural network. A 3D environment was created for the introduction of the data describing the gesture into the database. A classification accuracy of 95% was achieved for the hand flexion and extension gesture divided into three levels for each hand. The populated database may also be used to classify other gestures involving hand rotation.


Assuntos
Gestos , Redes Neurais de Computação , Bases de Dados Factuais , Mãos , Humanos , Movimento (Física) , Punho
13.
PLoS One ; 15(6): e0235175, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32569335

RESUMO

PURPOSE: We aim to develop a robust 4D MRI method for large FOVs enabling the extraction of irregular respiratory motion that is readily usable with all MRI machines and thus applicable to support a wide range of interventional settings. METHOD: We propose a 4D MRI reconstruction method to capture an arbitrary number of breathing states. It uses template updates in navigator slices and search regions for fast and robust vessel cross-section tracking. It captures FOVs of 255 mm x 320 mm x 228 mm at a spatial resolution of 1.82 mm x 1.82 mm x 4mm and temporal resolution of 200ms. A total of 37 4D MRIs of 13 healthy subjects were reconstructed to validate the method. A quantitative evaluation of the reconstruction rate and speed of both the new and baseline method was performed. Additionally, a study with ten radiologists was conducted to assess the subjective reconstruction quality of both methods. RESULTS: Our results indicate improved mean reconstruction rates compared to the baseline method (79.4% vs. 45.5%) and improved mean reconstruction times (24s vs. 73s) per subject. Interventional radiologists perceive the reconstruction quality of our method as higher compared to the baseline (262.5 points vs. 217.5 points, p = 0.02). CONCLUSIONS: Template updates are an effective and efficient way to increase 4D MRI reconstruction rates and to achieve better reconstruction quality. Search regions reduce reconstruction time. These improvements increase the applicability of 4D MRI as a base for seamless support of interventional image guidance in percutaneous interventions.


Assuntos
Imagem por Ressonância Magnética , Respiração , Humanos , Processamento de Imagem Assistida por Computador , Movimento (Física)
14.
Proc Biol Sci ; 287(1929): 20200180, 2020 06 24.
Artigo em Inglês | MEDLINE | ID: mdl-32576109

RESUMO

Corals rely almost exclusively on the ambient flow of water to support their respiration, photosynthesis, prey capture, heat exchange and reproduction. Coral tentacles extend to the flow, interact with it and oscillate under the influence of waves. Such oscillating motions of flexible appendages are considered adaptive for reducing the drag force on flexible animals in wave-swept environments, but their significance under slower flows is unclear. Using in situ and laboratory measurements of the motion of coral tentacles under wave-induced flow, we investigated the dynamics of the tentacle motion and its impact on mass transfer. We found that tentacle velocity preceded the water velocity by approximately one-quarter of a period. This out-of-phase behaviour enhanced mass transfer at the tentacle tip by up to 25% as compared with an in-phase motion. The enhancement was most pronounced under flows slower than 3.2 cm s-1, which are prevalent in many coral-reef environments. We found that the out-of-phase motion results from the tentacles' elasticity, which can presumably be modified by the animal. Our results suggest that the mechanical properties of coral tentacles may represent an adaptive advantage that improves mass transfer under the limiting conditions of slow ambient flows. Because the mechanism we describe operates by enhancing convective processes, it is expected to enhance other fitness-determining transport phenomena such as heat exchange and particle capture.


Assuntos
Antozoários/fisiologia , Animais , Recifes de Corais , Elasticidade , Temperatura Alta , Movimento (Física) , Fotossíntese , Respiração , Movimentos da Água
15.
Proc Biol Sci ; 287(1927): 20200607, 2020 05 27.
Artigo em Inglês | MEDLINE | ID: mdl-32396797

RESUMO

The human visual field, on the temporal side, extends to at least 90° from the line of sight. Using a two-alternative forced-choice procedure in which observers are asked to report the direction of motion of a Gabor patch, and taking precautions to exclude unconscious eye movements in the direction of the stimulus, we show that the limiting eccentricity of image-forming vision can be established with precision. There are large, but reliable, individual differences in the limiting eccentricity. The limiting eccentricity exhibits a dependence on log contrast; but it is not reduced when the modulation visible to the rods is attenuated, a result compatible with the histological evidence that the outermost part of the retina exhibits a high density of cones. Our working hypothesis is that only one type of neural channel is present in the far periphery of the retina, a channel that responds to temporally modulated stimuli of low spatial frequency and that is directionally selective.


Assuntos
Campos Visuais , Sensibilidades de Contraste , Feminino , Humanos , Movimento (Física) , Retina , Células Fotorreceptoras Retinianas Cones , Acuidade Visual
16.
Nan Fang Yi Ke Da Xue Xue Bao ; 40(3): 445-452, 2020 Mar 30.
Artigo em Chinês | MEDLINE | ID: mdl-32376586

RESUMO

As a new type of micro-/nanomachines, self-propelled micro-/nanomotors (MNMs) can convert chemical or external energies from the surrounding environment into mechanical forces to produce autonomous motion. The ability of autonomous movement allows these MNMs to move actively to the targeted locations, and thus confers great potentials on the MNMs for applications in biomedicine, especially in drug delivery. MNMs have been shown to effectively load therapeutic payloads for active delivery to the disease site, which greatly improves the therapeutic efficacy and reduces side effects compared with the traditional nanodrugs. In this review, we provide an overview of different propulsion mechanisms of MNMs, including chemical propulsion based on redox reaction and external field propulsion driven by external energy such as light, magnetic field, electric field and ultrasound, followed by a review of the recent progress in active drug delivery based on MNMs in the past decade. We also discuss the current challenges and future perspectives of the application of the MNMs.


Assuntos
Nanoestruturas , Nanotecnologia , Sistemas de Liberação de Medicamentos , Movimento (Física) , Oxirredução
17.
Nat Commun ; 11(1): 2405, 2020 05 15.
Artigo em Inglês | MEDLINE | ID: mdl-32415064

RESUMO

Fiber-based electronics enabling lightweight and mechanically flexible/stretchable functions are desirable for numerous e-textile/e-skin optoelectronic applications. These wearable devices require low-cost manufacturing, high reliability, multifunctionality and long-term stability. Here, we report the preparation of representative classes of 3D-inorganic nanofiber network (FN) films by a blow-spinning technique, including semiconducting indium-gallium-zinc oxide (IGZO) and copper oxide, as well as conducting indium-tin oxide and copper metal. Specifically, thin-film transistors based on IGZO FN exhibit negligible performance degradation after one thousand bending cycles and exceptional room-temperature gas sensing performance. Owing to their great stretchability, these metal oxide FNs can be laminated/embedded on/into elastomers, yielding multifunctional single-sensing resistors as well as fully monolithically integrated e-skin devices. These can detect and differentiate multiple stimuli including analytes, light, strain, pressure, temperature, humidity, body movement, and respiratory functions. All of these FN-based devices exhibit excellent sensitivity, response time, and detection limits, making them promising candidates for versatile wearable electronics.


Assuntos
Nanopartículas Metálicas/química , Nanofibras/química , Dispositivos Eletrônicos Vestíveis , Consumo de Bebidas Alcoólicas , Técnicas Biossensoriais , Testes Respiratórios , Cobre/química , Elastômeros , Etanol/análise , Análise de Elementos Finitos , Gálio/química , Humanos , Índio/química , Teste de Materiais , Movimento (Física) , Poliestirenos/química , Semicondutores , Espectrofotometria Ultravioleta , Temperatura , Têxteis , Óxido de Zinco/química
18.
Nat Commun ; 11(1): 2637, 2020 05 26.
Artigo em Inglês | MEDLINE | ID: mdl-32457457

RESUMO

Metachronal waves commonly exist in natural cilia carpets. These emergent phenomena, which originate from phase differences between neighbouring self-beating cilia, are essential for biological transport processes including locomotion, liquid pumping, feeding, and cell delivery. However, studies of such complex active systems are limited, particularly from the experimental side. Here we report magnetically actuated, soft, artificial cilia carpets. By stretching and folding onto curved templates, programmable magnetization patterns can be encoded into artificial cilia carpets, which exhibit metachronal waves in dynamic magnetic fields. We have tested both the transport capabilities in a fluid environment and the locomotion capabilities on a solid surface. This robotic system provides a highly customizable experimental platform that not only assists in understanding fundamental rules of natural cilia carpets, but also paves a path to cilia-inspired soft robots for future biomedical applications.


Assuntos
Células Artificiais , Cílios/fisiologia , Células Artificiais/ultraestrutura , Cílios/ultraestrutura , Simulação por Computador , Hidrodinâmica , Magnetismo , Modelos Biológicos , Movimento (Física) , Impressão Tridimensional/instrumentação , Robótica/instrumentação
19.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao ; 42(2): 139-146, 2020 Apr 28.
Artigo em Chinês | MEDLINE | ID: mdl-32385018

RESUMO

Objective To prospectively evaluate the correlation between intravoxel incoherent motion (IVIM)-derived parameters and CT perfusion parameters as well as the pathological grade in insulinoma. Methods A total of 55 patients with suspected insulinoma undergoing IVIM and CT perfusion scans were prospectively enrolled. The images were post-processed to obtain IVIM parameters including apparent diffusion coefficient (ADC),diffusion (D),perfusion correlated diffusion (D*),and f,and CT perfusion parameters including blood flow (BF),blood volume (BV),and permeability (PM). The pathological specimens were stained to obtain pathological parameters including the grading,ki-67 index,and the mitotic count. The IVIM derived parameters of normal pancreas including head,body,and tail as well as that of the pancreatic insulinoma were compared. The correlation between IVIM parameters and CT perfusion parameters as well as the pathological parameters was analyzed. Results ADC and D values of pancreatic tail were significantly lower than those of the pancreatic head and neck (all P<0.001). There were significant differences in all IVIM parameters between insulinoma and normal pancreas (all P<0.001). The ADC and f value of the normal pancreas was positively correlated with BF (r=0.437,P=0.003;r=0.357,P=0.010). There is no correlation between the remaining IVIM parameters and the CT perfusion parameters as well as between IVIM parameters and pathological parameters (all P>0.05). Conclusions IVIM parameters differ at different anatomical parts of normal pancreas. IVIM parameters can distinguish normal pancreatic parenchyma from insulinoma. The ADC value is weakly correlated with BF.


Assuntos
Insulinoma/diagnóstico por imagem , Neoplasias Pancreáticas/diagnóstico por imagem , Imagem de Difusão por Ressonância Magnética , Humanos , Movimento (Física) , Reprodutibilidade dos Testes , Tomografia Computadorizada por Raios X
20.
Nat Commun ; 11(1): 2149, 2020 05 01.
Artigo em Inglês | MEDLINE | ID: mdl-32358525

RESUMO

State monitoring of the complex system needs a large number of sensors. Especially, studies in soft electronics aim to attain complete measurement of the body, mapping various stimulations like temperature, electrophysiological signals, and mechanical strains. However, conventional approach requires many sensor networks that cover the entire curvilinear surfaces of the target area. We introduce a new measuring system, a novel electronic skin integrated with a deep neural network that captures dynamic motions from a distance without creating a sensor network. The device detects minute deformations from the unique laser-induced crack structures. A single skin sensor decodes the complex motion of five finger motions in real-time, and the rapid situation learning (RSL) ensures stable operation regardless of its position on the wrist. The sensor is also capable of extracting gait motions from pelvis. This technology is expected to provide a turning point in health-monitoring, motion tracking, and soft robotics.


Assuntos
Técnicas Biossensoriais/métodos , Nanopartículas Metálicas/química , Movimento (Física) , Prata/química , Dispositivos Eletrônicos Vestíveis , Humanos , Temperatura , Punho
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