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1.
Arch Endocrinol Metab ; 64(3): 276-281, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32555994

RESUMO

OBJECTIVE: Climacterium is associated with elevated leptin levels and increased risk of cardiovascular disorders. Conflicting data diverge on whether high leptin levels in climacterium reflect increasing adipose mass or, at least partially, age-related hormonal changes. This study addresses this issue in women from a Brazilian state with a low human development index. SUBJECTS AND METHODS: A case-control study was conducted, enrolling 136 women from the state of Maranhão, 52 (38.2%) climacteric and 84 (61.8%) non-climacteric. Biometric, biochemical, hormonal and immunological parameters were analyzed. RESULTS: Climacteric women showed a moderately increased waist/hip ratio (0.894 versus 0.834, p < 0.05), sustained body mass index (27.46 versus 28.68, p > 0.05) increased leptin levels (9.59 versus 7.13, p < 0.05) and no evidence of metabolic syndrome. No other parameters were altered. The climacteric cohort didn't show significant body fat gains but displayed a typical age-related redistribution of adipose tissue. Even so, leptin levels were significantly elevated compared with non-climacteric women. CONCLUSIONS: Altogether, these data support the hypothesis that leptin is elevated, at least partially, as a function of age and climacterium and is not necessarily correlated with metabolic dysfunction and systemic inflammation. Further studies are needed to evaluate the impact of higher leptin levels on postmenopausal women. Arch Endocrinol Metab. 2020;64(3):276-81.


Assuntos
Adiposidade/fisiologia , Climatério/sangue , Leptina/sangue , Adulto , Fatores Etários , Idoso , Biomarcadores/sangue , Estudos de Casos e Controles , Climatério/fisiologia , Estudos de Coortes , Feminino , Humanos , Pessoa de Meia-Idade , Fatores Socioeconômicos
2.
PLoS One ; 14(12): e0218497, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31830047

RESUMO

This study aims to investigate the association between health conditions and overweight in climacteric women assisted by primary care professionals. It is a cross-sectional study conducted with 874 women from 40 to 65 years of age, selected by probabilistic sampling between August 2014 and August 2015. In addition to the outcome variable, overweight and obesity, other variables such as sociodemographic, reproductive, clinical, eating and behavioural factors were evaluated. Descriptive analyses of the variables investigated were performed to determine their frequency distributions. Then, bivariate analyses were performed through Poisson regression. For the multivariate analyses, hierarchical Poisson regression was used to identify factors associated with overweight and obesity in the climacteric period. The prevalence of overweight and obesity was 74%. Attending public school (PR: 1.30-95% CI 1.14-1.50), less schooling (PR: 1.11-95% CI 1.01-1.23), gout (PR: 1.18-95% CI 1.16-1.44), kidney disease (PR: 1.18-95% CI 1.05-1.32), metabolic syndrome (MS) (PR: 1.19-95% CI 1.05-1.34) and fat intake (PR: 1.12-95% CI 1.02-1.23) were considered risk factors for overweight. Having the first birth after 18 years of age (PR: 0.89-95% CI 0.82 to 0.97) was shown to be a protective factor for overweight and obesity. The presence of overweight and obesity is associated with sociodemographic, reproductive, clinical and eating habits.


Assuntos
Climatério , Obesidade/epidemiologia , Sobrepeso/epidemiologia , Adulto , Idoso , Índice de Massa Corporal , Brasil/epidemiologia , Estudos Transversais , Feminino , Humanos , Pessoa de Meia-Idade , Prevalência , Fatores de Risco
3.
Adv Gerontol ; 32(4): 516-523, 2019.
Artigo em Russo | MEDLINE | ID: mdl-31800178

RESUMO

The aim of our study is to search diagnostic tools for early detection of prenosological melatonin deficiency in postmenopausal women and women in menopausal transition with climacteric syndrome for establishment effective personalized prevention and treatment programs. In this study 221 women were enrolled. They were divided into four groups: the 1st group - 39 women in menopausal transition with climacteric syndrome, the 2nd group - 104 menopausal women with climacteric syndrome, the 3rd group - 41 women with physiological menopause, the 4th group - 37 healthy women in reproductive-age. The study was conducted using the test for detecting melatonin deficiency, women's health questionnaire (WHQ), and morning level detection of 6-sulfatoxymelatonin in urine. A new prenosological state - perimenopausal melatonin deficiency syndrome was build on the data obtained. It is appropriate to evaluate prognosis of melatonin treatment in women with climacteric syndrome during the planning of personalized prevention and treatment programs. The assessment of prognosis is carried out with the help of the discriminant mathematical model, which is the basis of personalized management of quality of life in women with climacteric syndrome. This system is based on participatory principles.


Assuntos
Climatério , Melatonina , Medicina de Precisão , Qualidade de Vida , Adulto , Feminino , Humanos , Melatonina/deficiência , Melatonina/urina , Menopausa , Pessoa de Meia-Idade , Perimenopausa/urina , Inquéritos e Questionários , Síndrome
4.
PLoS One ; 14(12): e0225886, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31800597

RESUMO

European pears (Pyrus communis L.) require a range of cold-temperature exposure to induce ethylene biosynthesis and fruit ripening. Physiological and hormonal responses to cold temperature storage in pear have been well characterized, but the molecular underpinnings of these phenomena remain unclear. An established low-temperature conditioning model was used to induce ripening of 'D'Anjou' and 'Bartlett' pear cultivars and quantify the expression of key genes representing ripening-related metabolic pathways in comparison to non-conditioned fruit. Physiological indicators of pear ripening were recorded, and fruit peel tissue sampled in parallel, during the cold-conditioning and ripening time-course experiment to correlate gene expression to ontogeny. Two complementary approaches, Nonparametric Multi-Dimensional Scaling and efficiency-corrected 2-(ΔΔCt), were used to identify genes exhibiting the most variability in expression. Interestingly, the enhanced alternative oxidase (AOX) transcript abundance at the pre-climacteric stage in 'Bartlett' and 'D'Anjou' at the peak of the conditioning treatments suggests that AOX may play a key and a novel role in the achievement of ripening competency. There were indications that cold-sensing and signaling elements from ABA and auxin pathways modulate the S1-S2 ethylene transition in European pears, and that the S1-S2 ethylene biosynthesis transition is more pronounced in 'Bartlett' as compared to 'D'Anjou' pear. This information has implications in preventing post-harvest losses of this important crop.


Assuntos
Climatério/genética , Temperatura Baixa , Frutas/fisiologia , Proteínas Mitocondriais/genética , Oxirredutases/genética , Proteínas de Plantas/genética , Pyrus/fisiologia , Transcrição Genética
5.
Ann Agric Environ Med ; 26(4): 600-605, 2019 Dec 19.
Artigo em Inglês | MEDLINE | ID: mdl-31885234

RESUMO

OBJECTIVE: The aim of the study was evaluation of the relationship between severity of symptoms of climacteric syndrome, depressive disorders and sleep problems, and the self-rated work ability of peri-menopausal and post-menopausal women in non-manual employment. MATERIAL AND METHODS: The study included 287 women aged 45-60 years, employed in various institutions as non-manual workers. Work Ability Index, Greene Climacteric Scale, Beck Depression Inventory, and Athens Insomnia Scale were used. RESULTS: The examined peri-menopausal and post-menopausal women in non-manual employment obtained good work ability on the Work Ability Index. The severity of menopausal syndrome, according to the Greene Climacteric Scale, was moderate, placing the examined women between results for the general population of women and the pattern for menopausal women. Depressive disorders ranked between low mood and moderate depression. No depression was observed in 59% of the women, whereas moderate depression was observed in 39%, and severe depression in only 2%. Sleep disorders were on the border of normal range. As many as 46% of the women had no sleep problems, which was on the border of normal range in 36%. Only 19% of the examined women suffered from insomnia. Work ability correlated negatively with depression and insomnia severity, as well as with psychological and vasomotor symptoms of climacteric syndrome, but not to its somatic symptoms. CONCLUSIONS: Preventing the occurrence and treatment of menopausal symptoms, sleep and mood disorders may contribute to maintaining the work ability of women in peri- and post-menopausal age.


Assuntos
Climatério/fisiologia , Depressão/fisiopatologia , Perimenopausa/psicologia , Pós-Menopausa/psicologia , Distúrbios do Início e da Manutenção do Sono/fisiopatologia , Climatério/psicologia , Depressão/economia , Depressão/psicologia , Emprego , Feminino , Humanos , Pessoa de Meia-Idade , Perimenopausa/fisiologia , Pós-Menopausa/fisiologia , Distúrbios do Início e da Manutenção do Sono/economia , Distúrbios do Início e da Manutenção do Sono/psicologia , Avaliação da Capacidade de Trabalho
6.
Rev Bras Enferm ; 72(suppl 3): 154-161, 2019 Dec.
Artigo em Inglês, Português | MEDLINE | ID: mdl-31851248

RESUMO

OBJECTIVE: to evaluate the quality of life of primary care nurses in the climacteric. METHOD: A cross-sectional descriptive-analytic study, performed with 98 female nurses, aged 40-65 years, using the WHOQOL-Bref questionnaire. RESULTS: the worst level of quality of life was observed for professionals aged 50-59 years, non-white, specialists, divorced or widowed, with children, a lower income, with another employment relationship, a weekly workload of more than 40 hours, who consumed alcoholic beverages weekly, with chronic disease, in continuous use of medications, sedentary, who did not menstruate and did not receive hormonal treatment, and who went through menopause between the ages of 43-47 years. CONCLUSION: Although the variables "physical activity" and "age" have a statistically significant association with quality of life, other variables seem to interfere in these professionals' lives, indicating the need for a more critical and deep reflection on these relations.


Assuntos
Enfermeiras e Enfermeiros/psicologia , Enfermagem de Atenção Primária/normas , Qualidade de Vida/psicologia , Adulto , Fatores Etários , Idoso , Climatério/psicologia , Grupos de Populações Continentais/estatística & dados numéricos , Estudos Transversais , Feminino , Humanos , Masculino , Menopausa/psicologia , Pessoa de Meia-Idade , Enfermagem de Atenção Primária/métodos , Enfermagem de Atenção Primária/psicologia , Inquéritos e Questionários , Carga de Trabalho/psicologia , Carga de Trabalho/normas
7.
BMC Psychol ; 7(1): 66, 2019 Oct 21.
Artigo em Inglês | MEDLINE | ID: mdl-31639054

RESUMO

BACKGROUND: Recent Life Changes Questionnaire (RLCQ) developed by Richard Rahe has enabled quantification of stress by analyzing life events. The overall aim of the study was to create a reliable version of the Rahe's RLCQ for measuring stress in individuals living in developing countries and assess its validity. This paper discusses criterion validation of the adapted RLCQ in urban communities in Pakistan. METHODS: This is a criterion validation study. Four urban communities of Karachi, Pakistan were selected for the study in which households were randomly chosen. Two data collectors were assigned to administer the adapted RLCQ to eligible participants after obtaining written informed consent. Following this interaction, two psychologists interviewed the same participants with a diagnostic gold standard of Mini International Neuropsychiatric Interview (MINI) which is utilized in usual practice within Pakistan to confirm the presence of stress related mental disorders such as Depression, Anxiety, Dysthymia, Suicide, Phobia, OCD, Panic Disorder, PTSD, Drug abuse and dependence, Alcohol abuse and dependence, Eating Disorders and Antisocial Personality Disorder to validate the accuracy of the adapted RLCQ. We generated the ROC curves for the adapted RLCQ with suggested cut-offs, and analyzed the sensitivity and specificity of the adapted RLCQ. RESULTS: The area under the receiver operating characteristic curve (ROC) of common mental disorders such as depression and anxiety was 0.64, where sensitivity was 66%, specificity was 56% and the corresponding cut off from the adapted RLCQ was 750. Individuals scoring ≥750 were classified as high stress and vice versa. In contrast, the area under the ROC curve for serious mental disorder and adverse outcomes such as suicide, bipolar and dysthymia was 0.75, where sensitivity was 72% and specificity was 60% at the cut off of 800 on the adapted RLCQ. Individuals scoring ≥800 were classified as high stress and vice versa. The rate of agreement between the two psychologists was 94.32% (Kappa = 0.84). CONCLUSION: The adapted and validated RLCQ characterizes common mental disorders such as depression and anxiety with moderate accuracy and severe mental disorders such as suicide, bipolar and dysthymia with high accuracy. TRIAL REGISTRATION: Clinicaltrials.gov NCT02356263 . Registered January 28, 2015. (Observational Study Only).


Assuntos
Climatério/psicologia , Transtornos Mentais/diagnóstico , Estresse Psicológico , Inquéritos e Questionários , Adulto , Ansiedade , Depressão , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Paquistão , Escalas de Graduação Psiquiátrica , Qualidade de Vida , Curva ROC , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , População Urbana
8.
Medicine (Baltimore) ; 98(37): e17039, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31517823

RESUMO

BACKGROUND: Climacteric women experience various disorders, including hot flush, depression, insomnia, arthralgia, and hand and foot numbness. Dangguijakyaksan is among the most common treatments for climacteric syndrome, and its effect on depression, insomnia, hot flush and quality of life (QOL) in climacteric women has been reported multiple times. A recent animal study found dangguijakyaksan decreased serum lipid factors and improved blood circulation in a menopausal rat model; however, these effects have not been assessed in clinical trials. This study aims to assess the clinical effects and safety of dangguijakyaksan for lower-extremity blood circulation disturbances in climacteric women. METHODS: This is a single-center, randomized, double-blinded, placebo-controlled pilot study that will be conducted at Dunsan Korean Medicine Hospital at Daejeon University. Forty-six climacteric women with lower-extremity blood circulation disturbances will be recruited and randomized (1:1) into either the dangguijakyaksan or placebo group. After 8 weeks of administration, the effects and safety of dangguijakyaksan will be assessed.The primary outcome is the visual analogue scale for lower-extremity blood circulation disturbances, and it will be assessed on visits 1, 2, and 3. The secondary outcomes, Kupperman's index and blood deficiency scoring system, will be assessed on visits 1, 2, and 3, and accelerated photoplethysmography and digital infrared thermal imaging will be performed on visits 1 and 3. Moreover, blood lipid profile, follicle-stimulating hormone, and estradiol levels will be measured at the screening visit and visit 3. Blood tests will be performed at the screening visit and visit 3 to assess the safety of dangguijakyaksan. Statistical analysis will be performed using R-3.3.3 (Another Canoe), and within-group study variable differences after drug administration will be analyzed using paired t-test or Wilcoxon signed-rank test. DISCUSSION: We expect to confirm the effects and safety of dangguijakyaksan on lower-extremity blood circulation disturbances in menopause, which would provide foundational data for planning subsequent studies.


Assuntos
Circulação Sanguínea/efeitos dos fármacos , Fármacos Cardiovasculares/uso terapêutico , Climatério , Medicamentos de Ervas Chinesas/uso terapêutico , Ensaios Clínicos Controlados Aleatórios como Assunto , Método Duplo-Cego , Feminino , Humanos , Extremidade Inferior , Pessoa de Meia-Idade , Projetos Piloto
9.
BMC Plant Biol ; 19(1): 369, 2019 Aug 22.
Artigo em Inglês | MEDLINE | ID: mdl-31438855

RESUMO

BACKGROUND: Cucumis melo is a suitable study material for investigation of fruit ripening owing to its climacteric nature. Long non-coding RNAs have been linked to many important biological processes, such as fruit ripening, flowering time regulation, and abiotic stress responses in plants. However, knowledge of the regulatory roles of lncRNAs underlying the ripening process in C. melo are largely unknown. In this study the complete transcriptome of Cucumis melo L. cv. Hetao fruit at four developmental stages was sequenced and analyzed. The potential role of lncRNAs was predicted based on the function of differentially expressed target genes and correlated genes. RESULTS: In total, 3857 lncRNAs were assembled and annotated, of which 1601 were differentially expressed between developmental stages. The target genes of these lncRNAs and the regulatory relationship (cis- or trans-acting) were predicted. The target genes were enriched with GO terms for biological process, such as response to auxin stimulus and hormone biosynthetic process. Enriched KEGG pathways included plant hormone signal transduction and carotenoid biosynthesis. Co-expression network construction showed that LNC_002345 and LNC_000154, which were highly expressed, might co-regulate with mutiple genes associated with auxin signal transduction and acted in the same pathways. We identified lncRNAs (LNC_000987, LNC_000693, LNC_001323, LNC_003610, LNC_001263 and LNC_003380) that were correlated with fruit ripening and the climacteric, and may participate in the regulation of ethylene biosynthesis and metabolism and the ABA signaling pathway. A number of crucial transcription factors, such as ERFs, WRKY70, NAC56, and NAC72, may also play important roles in the regulation of fruit ripening in C. melo. CONCLUSIONS: Our results predict the regulatory functions of the lncRNAs during melon fruit development and ripening, and 142 highly expressed lncRNAs (average FPKM > 100) were identified. These lncRNAs participate in the regulation of auxin signal transduction, ethylene, sucrose biosynthesis and metabolism, the ABA signaling pathway, and transcription factors, thus regulating fruit development and ripening.


Assuntos
Cucumis melo/genética , Frutas/genética , RNA Longo não Codificante/fisiologia , RNA de Plantas/fisiologia , Mapeamento Cromossômico , Climatério , Cucumis melo/crescimento & desenvolvimento , Frutas/crescimento & desenvolvimento , Perfilação da Expressão Gênica , Genoma de Planta , Fenótipo , Reguladores de Crescimento de Planta/metabolismo , Análise de Sequência de RNA , Transdução de Sinais , Transcriptoma
10.
ScientificWorldJournal ; 2019: 1872536, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31320839

RESUMO

Background: Cardiovascular diseases are leading causes of death worldwide. Recent studies suggest that infection by some viruses, including the human papillomavirus (HPV), may increase the risk of developing atheromatous lesions on coronary arteries. However, there is a lack of data regarding the possible association between HPV infection and coronary artery disease (CAD) in women. Objective: To investigate whether HPV infection is associated with the occurrence of CAD among climacteric women. Methods: The presence of CAD and cervical HPV DNA was investigated in 52 climacteric women. Social and demographic variables and metabolic profiles were also investigated. Results: Among 27 women with CAD, 16 were positive for HPV, whereas 11 were negative. The presence of cervical HPV was strongly associated with CAD, after adjusting for demographic variables, health and sexual behaviors, comorbidities, and known cardiovascular risk factors. HPV-positive women showed a greater likelihood of having CAD (odds ratio [OR] = 3.74; 95% confidence interval [CI]: 1.16 to 11.96) as compared with HPV-negative women, particularly those infected with high-risk HPV types (OR = 4.90; 95% CI: 1.26 to 19.08). Conclusion: These results support the hypothesis that HPV infection might be associated with CAD among climacteric women, though further studies are needed to investigate the mechanisms involved.


Assuntos
Climatério , Doença da Artéria Coronariana/epidemiologia , Doença da Artéria Coronariana/etiologia , Papillomaviridae , Infecções por Papillomavirus/epidemiologia , Adulto , Fatores Etários , Idoso , Feminino , Humanos , Pessoa de Meia-Idade , Razão de Chances , Infecções por Papillomavirus/complicações , Infecções por Papillomavirus/virologia , Vigilância em Saúde Pública , Medição de Risco , Fatores de Risco , Fatores Sexuais , Fatores Socioeconômicos
11.
Adv Gerontol ; 32(1-2): 159-165, 2019.
Artigo em Russo | MEDLINE | ID: mdl-31228383

RESUMO

Ovarian failure is accompanied by a decrease in sexual function, which plays quite an important rolefor modern women. Purpose: to evaluate the impact of complex non-drug programs for correcting climacteric disorders on the sexual function of women with metabolic syndrome. We examined 330 women aged 45-50 with a climacteric syndrome of mild and moderate severity against the background of the metabolic syndrome. Patients were formed into 5 groups. All patients received standard treatment.Women of the main group and comparison groups were treated with exercise therapy, drinking balneotherapy, additional oral intake of multivitamins and minerals, and preformed physical factors in various combinations: vibrotherapy, full-spectrum and selective chromotherapy, melody therapy, aromatherapy, aeroionotherapy. In the control group, only standard treatment was used. A dynamic evaluation of the Sexual Function Index wasperformed. With the simultaneous use of vibration therapy, chromotherapy, melody therapy, aeroionotherapy, aromatherapy, the index of female sexual function increases as much as 26% in patients with menopausal syndrome of mild degree and 20% in patients with moderate menopausal syndrome. Thus, the complex non-drug correction of menopausal disorders with simultaneous application of all specified physiotherapeutic can improve the quality of life of a woman with a metabolic syndrome due to a positive effect on its sexual component.


Assuntos
Climatério , Síndrome Metabólica , Idoso , Feminino , Humanos , Síndrome Metabólica/complicações , Pessoa de Meia-Idade , Perimenopausa , Modalidades de Fisioterapia , Qualidade de Vida
12.
Sex Reprod Healthc ; 20: 72-76, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-31084823

RESUMO

OBJECTIVE: To investigate the association between psychosocial factors and postpartum depression. METHODS: A cross-sectional design was used. The sample consisted of 166 postpartum mothers recruited by cluster sampling from two public health centers in South Jakarta, Jakarta Province, Indonesia, during February to April 2016. Data collection was through home visits. Instruments employed were: the Edinburgh Postnatal Depression Scale (EPDS); the Childcare Stress Inventory; the Postpartum Support Questionnaire to measure social support; the Dyad Adjustment Scale to measure marital satisfaction; the Rosenberg Self-esteem Scale; and the modified Life Events Questionnaire to measure stressful life events. Data analysis consisted of linear regression. RESULTS: The prevalence of postpartum depression was 19.88%. Childcare stress, marital satisfaction and stressful life events were associated with postpartum depression (R2 = 0.298, F = 16.794, p-value < 0.001). Stressful life events explained the most variance in EPDS scores (ß = 0.220, P-value < 0.001), followed by marital satisfaction (ß = -0.321, P-value < 0.01) and childcare stress (ß = 0.008, P-value < 0.01). CONCLUSION: The results of this study can be used to inform the screening of vulnerable sub-groups for postpartum depression and to develop nursing interventions that might alleviate postpartum depression.


Assuntos
Climatério/psicologia , Depressão Pós-Parto/epidemiologia , Cuidado do Lactente/psicologia , Relações Interpessoais , Mães/psicologia , Adolescente , Adulto , Estudos Transversais , Feminino , Humanos , Indonésia/epidemiologia , Recém-Nascido , Prevalência , Escalas de Graduação Psiquiátrica , Fatores de Risco , Estresse Psicológico/psicologia , Inquéritos e Questionários , Adulto Jovem
13.
Anthropol Anz ; 76(4): 293-304, 2019 Oct 30.
Artigo em Inglês | MEDLINE | ID: mdl-31033995

RESUMO

Menopause is a universal physiological process of women's midlife exhibiting a wide variety of symptoms in a different population. Limited studies have examined the association of menopause symptoms with respect to body mass index (BMI) and osteoporosis among rural Indian women. The aim of the present cross-sectional study is an attempt to assess the association of menopause symptoms with body mass index and osteoporosis among rural women of Kanpur, North India. A total sample of 351 women ranging in age between 35 to 55 years was randomly selected from six villages of Kanpur (North India). Menopausal symptoms were measured by using the Greene Climacteric scale. T-score of each subject was gauged from the calcaneus by employing ultrasound based bone densitometer. In anthropometric measurements, height and weight were taken and body mass index (BMI = weight/height2 kg/m2) was calculated. The results indicated that women with psychological (20.8 vs 19.8, p < 0.05), anxiety (21.0 vs 19.5, p < 0.01), and vasomotor (21.6 vs 20.0, p < 0.001) symptoms had a significantly higher mean value of body mass index than their asymptomatic counterparts. The mean value of T scores in the women with psychological (-2.36 vs -1.97, p < 0.05), anxiety (-2.36 vs -2.09, p < 0.05), depression (-2.38 vs -1.97, p < 0.01), somatic (-2.45 vs -1.86, p < 0.001), vasomotor (-2.49 vs -2.15, p < 0.01) and loss of interest in sex (-2.43 vs -1.76, p < 0.001) symptoms was significantly lower than their counterparts with no symptoms. Binary logistic regression analysis confirmed that women with menopausal symptoms had a two-fold higher risk of developing osteoporosis than asymptomatic women. A positive and significant correlation of body mass index was noted with psychological, anxiety and vasomotor symptoms, whereas T-score had a significant association with all the menopausal symptoms.


Assuntos
Índice de Massa Corporal , Climatério , Menopausa , Osteoporose , Adulto , Estudos Transversais , Feminino , Humanos , Índia , Pessoa de Meia-Idade , Osteoporose/epidemiologia , Inquéritos e Questionários
14.
Health Psychol ; 38(3): 206-216, 2019 03.
Artigo em Inglês | MEDLINE | ID: mdl-30762400

RESUMO

OBJECTIVE: The sustainment of gains for cancer patients provided psychosocial interventions is unclear. Furthermore, it is unknown whether interventions also yield long-term positive changes. The present study experimentally tests if an intervention delivered at cancer diagnosis could yield broad, long-term, changes in domains such as relationships, worldview, priorities, and goals. It was hypothesized that the intervention group would report more positive and fewer negative life changes during survivorship versus the control group. METHOD: Patients with Stage II/III breast cancer were randomized to biobehavioral intervention (BBI) or assessment only. At randomization, patients completed measures of cancer stress (Impact of Events Scale [IES]) and depressive symptoms (Center for Epidemiological Studies Depression scale [CES-D]). At the 24-month follow-up, survivors (N = 160) completed a thought listing task with 7 prompts (e.g., "relationships"). Patients listed thoughts about change since diagnosis and rated each for valence. Groups were compared on the frequency of positive/negative thoughts across prompts. Listed thoughts were content analyzed. RESULTS: BBI survivors reported significantly more positive changes (p < .05), controlling for IES and CES-D. Groups did not differ on negative changes. Patients with higher IES/CES-D scores reported more negative changes at 24 months (ps < .05). Content analysis revealed a predominance (13/23) of positive thought categories. CONCLUSIONS: Adding support for efficacy, BBI survivors reported significantly more positive life changes since diagnosis than survivors not receiving BBI. More generally, heightened stress/depressive symptoms at diagnosis foretold survivors' reporting of more negative changes. Thought listing is a strategy to obtain personalized accounts of life changes after breast cancer. (PsycINFO Database Record (c) 2019 APA, all rights reserved).


Assuntos
Neoplasias da Mama/psicologia , Sobreviventes de Câncer/psicologia , Terapia Cognitivo-Comportamental , Transtorno Depressivo/terapia , Adulto , Neoplasias da Mama/terapia , Climatério , Transtorno Depressivo/psicologia , Feminino , Humanos , Pessoa de Meia-Idade , Qualidade de Vida/psicologia , Perfil de Impacto da Doença
15.
J Sci Food Agric ; 99(8): 3792-3802, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-30666651

RESUMO

BACKGROUND: Large improvements have been realized on the accuracy of the determination of fruit quality. The relevance of the relationship between commonly used quality descriptors and their related chemical contents was here questioned under the influence of water supply reduction and postharvest cold storage. The study relied on three analyses: (1) a correlation table between quality descriptors and compound contents, (2) principal component analysis using the selected variables to see the quality discrimination dictated by treatments; and (3) linear correlation between content and descriptors according to treatments. RESULTS: The results indicate that abiotic parameters applied on mango fruits before or after harvest can affect the relationship between a quality descriptor and the content in compounds it is related to, here between titratable acidity and organic acid content and to a lesser extent between color, represented by hue angle values, and carotenoids, possibly creating bias in the final quality determination. A stronger relation between total soluble solids and total sugar content, were observed under mild abiotic stress. CONCLUSION: Fruit growth and postharvest storage conditions, such as irrigation and cold storage, can influence the actual correspondence between the compounds contents and the descriptors used to estimate fruit quality, particularly for pulp color, sugars and acids. © 2019 Society of Chemical Industry.


Assuntos
Irrigação Agrícola/métodos , Armazenamento de Alimentos/métodos , Frutas/química , Mangifera/crescimento & desenvolvimento , Água/análise , Ácidos/análise , Carotenoides/análise , Climatério , Cor , Frutas/crescimento & desenvolvimento , Frutas/metabolismo , Mangifera/química , Mangifera/metabolismo , Extratos Vegetais/análise , Controle de Qualidade , Açúcares/análise , Água/metabolismo
16.
Climacteric ; 22(1): 73-78, 2019 02.
Artigo em Inglês | MEDLINE | ID: mdl-30499736

RESUMO

OBJECTIVE: The study aimed to identify the factors associated with the sexual lives of perimenopausal and postmenopausal women in China. METHODS: A total of 426 participants were approached about this study from May 2012 to August 2013. In total, 252 cases were included in this study. One hundred and ninety-seven women who filled out the Quality of Sexual Life Questionnaire for Women (QSLQW) and the modified Kupperman Menopausal Index (KMI) had an active sexual life. Pearson's coefficient index was used to determine the correlation between the KMI and different domains of the QSLQW. Multivariable statistical analysis was performed to determine the correlation between different factors and the sexual life of perimenopausal and postmenopausal women. RESULTS: When the participants reported a higher KMI, they suffered lower sexual satisfaction (r = -0.16, p = 0.035), more severe sexual anxiety (r = -0.367, p = 4.9 × 10-7), and less sexual response (r = -0.21, p = 0.004). No correlation was found between the KMI and sexual communication, sexual attitude, and self-image. Multivariable statistical analysis showed that menopause status and higher KMI scores are associated with a decrease in sexual satisfaction among Chinese women (ß = -9.76, 95% CI -16.89 to -2.64 and ß = -0.41, 95% CI -0.68 to -0.15, respectively), and that the better the spousal relationship, the fewer deliveries and the higher the scores of sexual life quality (ß = 8.86, 95% CI -0.91 to 18.63 and ß = -6.65, 95% CI -11.83 to -1.48, respectively). CONCLUSION: Factors including parity, spousal relationship, menopausal status, and menopausal symptoms are associated with the quality of sexual life of perimenopausal and postmenopausal women in China.


Assuntos
Climatério/fisiologia , Climatério/psicologia , Orgasmo , Qualidade de Vida , Adulto , China , Estudos Transversais , Feminino , Humanos , Relações Interpessoais , Modelos Lineares , Menopausa , Pessoa de Meia-Idade , Análise Multivariada , Paridade
17.
J Aging Stud ; 47: 114-122, 2018 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-30447864

RESUMO

The purpose of this paper is twofold: first, we explore how older people (aged 69 to 85 years) living on the edge of relative poverty experience their everyday lives, and second, we investigate how they cope with their financial situation. We examine these aspects through 16 life story interviews to understand which paths these older people believe have led them to where they are today. First, we show how the older people highlight events or decisions in their life that mainly have an individual origin placing the responsibility of their current financial situation on themselves. We argue that these accounts reflect a change in the discourse on poverty; a transformation from poverty as collective destiny to poverty as the result of individual failure. Second, we show how these older people's control strategies vary across their life spans. In earlier phases of their lives, these older people attempted actively to improve their financial situation; however, in their old age, they focus more on adapting to and accepting the situation because their advanced age makes it difficult for them to use active coping strategies to overcome financial scarcity. Third, we argue that the imprints the interviewees received growing up in financial scarcity during the Second World War and the postwar years may have instilled them with silence and modesty, thus they are likely to adjust stoically.


Assuntos
Adaptação Psicológica , Envelhecimento/psicologia , Climatério , Pobreza , Idoso , Idoso de 80 Anos ou mais , Dinamarca , Feminino , Humanos , Entrevistas como Assunto , Masculino
18.
Climacteric ; 21(5): 502-508, 2018 10.
Artigo em Inglês | MEDLINE | ID: mdl-30269661

RESUMO

OBJECTIVES: This study aimed to assess the reliability and validity of the Menopause Visual Analogue Scale (MVAS) in measuring symptoms throughout the menopausal transition. METHODS: Two independent samples of women undergoing the menopausal transition completed both the MVAS and the Greene Climacteric Scale (GCS) at a women's mental health clinic between 2008 and 2016. Data for the first sample were obtained using a retrospective chart review of patients seen between 2008 and 2012 (N1 = 75) and data for the second sample came from a prospective study conducted between 2013 and 2016 (N2 = 86). Internal consistency was assessed using Cronbach's α and Pearson's correlation coefficient was used to evaluate concurrent validity. Bland-Altman plots were developed to assess the degree of agreement between the scales. RESULTS: Internal consistency for the physical and psychological domains of the MVAS was 0.80-0.81 and 0.92-0.94, respectively. Pearson's correlations between the MVAS and the GCS were high for both physical (rphys = 0.74-0.76, p < 0.01) and psychological (rpsych = 0.70-0.72, p < 0.01) components in both samples. Changes in MVAS physical and psychological scores in response to treatment were correlated with changes in GCS physical and psychological scores (rphys = 0.69, p < 0.01; rpsych = 0.49, p < 0.01) in the second sample. Bland-Altman plots indicate low to moderate levels of agreement between most portions of the MVAS and the GCS. CONCLUSIONS: These findings suggest that the MVAS has potential for assessing both severity and change in symptoms throughout the menopausal transition, subject to exploring limitations identified in the analysis and application to other populations.


Assuntos
Menopausa/fisiologia , Menopausa/psicologia , Escala Visual Analógica , Climatério , Feminino , Humanos , Pessoa de Meia-Idade , Psicometria , Reprodutibilidade dos Testes , Estudos Retrospectivos , Inquéritos e Questionários
19.
Top Stroke Rehabil ; 25(6): 397-402, 2018 09.
Artigo em Inglês | MEDLINE | ID: mdl-30028654

RESUMO

BACKGROUND: Stroke is a life-changing event for both stroke survivors and their family caregivers. After receiving acute care at the hospital, family members are expected to take care of stroke survivors at home and to continue treatment and rehabilitation. The new role of "informal caregiver" is a challenge that creates many difficulties for family caregivers that are not explicit in the Sri Lankan context. OBJECTIVES: This study aimed at exploring family caregivers' experiences of providing informal care for dependent stroke survivors. METHODS: The sample was chosen by purposive sampling with a maximum variation by age, ethnicity, religion, educational level, relationship, and monthly income. Ten informal family caregivers to stroke survivors with hemiplegia who had been treated at the National Hospital of Sri Lanka participated in in-depth interviews analyzed using conventional content analysis. RESULTS: Qualitative content analysis of data resulted in an overriding theme, "Caring with love, against all odds," along with four categories, "Life alterations," "Lack of resources," "Compassionate care," and "Coping strategies." Although the increased workload, restricted social life, physical problems, and knowledge and financial deficits were challenging for the family caregivers, self-strength and supportive social networks helped them to compassionately care for their stroke survivor. CONCLUSIONS: The phenomenon of family caregivers providing informal care for stroke survivors was explicated as compassionate care, notwithstanding numerous difficulties. The findings motivate further research and strategies to minimize family caregivers' burden and facilitate the positive aspects of caregiving to promote the health and well-being of both stroke survivors and their families.


Assuntos
Cuidadores/psicologia , Acidente Vascular Cerebral/epidemiologia , Acidente Vascular Cerebral/enfermagem , Adolescente , Adulto , Idoso , Climatério/psicologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Sri Lanka/epidemiologia , Acidente Vascular Cerebral/mortalidade , Sobrevida , Adulto Jovem
20.
Appl Nurs Res ; 41: 21-28, 2018 06.
Artigo em Inglês | MEDLINE | ID: mdl-29853209

RESUMO

Both men and women may experience multifaceted symptoms that are part of natural aging throughout the climacteric period. This study compared the prevalence and severity of climacteric symptoms between genders and identified the underlying clusters of climacteric symptoms and associated factors in midlife men and women. A cross-sectional study was done with 254 middle-aged Korean men (n = 129, M = 50.4) and women (n = 125, M = 49.5). Data were collected by self-administered surveys and analyzed using t-tests, chi-square tests, exploratory factor analysis, and regression analysis. Significant gender differences in overall climacteric symptoms were not detected except for muscle weakness, weight gain, and hot flashes. Climacteric symptoms were clustered as physical, vasomotor-genital, psychological, and metabolic dimensions, with the physical dimension being the most explanatory cluster. A significant gender effect was found only in the metabolic dimension after adjusting for the relevant covariates, and regular eating was significantly associated with all symptom clusters. This study offers evidence that most climacteric symptoms are shared by both men and women and emphasizes the importance of healthier lifestyles in the climacteric transition period. The findings highlight the critical need for integrated assessments of the multifactorial symptoms and of modifying poor lifestyles in both genders throughout the climacteric transition period.


Assuntos
Andropausa , Grupo com Ancestrais do Continente Asiático/psicologia , Climatério/psicologia , Menopausa/psicologia , Fatores Sexuais , Adulto , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , República da Coreia , Inquéritos e Questionários
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