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1.
Fundam Clin Pharmacol ; 34(3): 389-396, 2020 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-32394481

RESUMO

On March 16, 2020, the French Society of Pharmacology and Therapeutics put online a national Question and Answer (Q&A) website, https://sfpt-fr.org/covid19 on the proper use of drugs during the COVID-19 pandemic. The working group 'Drugs and COVID-19' was composed of a scientific council, an editorial team, and experts in the field. The first questions were posted online during the first evening of home-confinement in France, March 17, 2020. Six weeks later, 140 Q&As have been posted. Questions on the controversial use of hydroxychloroquine and to a lesser extent concerning azithromycin have been the most consulted Q&As. Q&As have been consulted 226 014 times in 41 days. This large visibility was obtained through an early communication on Twitter, Facebook, traditional print, and web media. In addition, an early communication through the French Ministry of Health and the French National Agency for Medicines and Health Products Safety ANSM had a large impact in terms of daily number of views. There is a pressing need to sustain a public drug information service combining the expertise of scholarly pharmacology societies, pharmacovigilance network, and the Ministry of Health to quickly provide understandable, clear, expert answers to the general population's concerns regarding COVID-19 and drug use and to counter fake news.


Assuntos
Betacoronavirus/efeitos dos fármacos , Informação de Saúde ao Consumidor/métodos , Infecções por Coronavirus , Serviços de Informação sobre Medicamentos/organização & administração , Pandemias , Pneumonia Viral , Sociedades Farmacêuticas , Infecções por Coronavirus/tratamento farmacológico , Infecções por Coronavirus/epidemiologia , Infecções por Coronavirus/virologia , França , Humanos , Pneumonia Viral/tratamento farmacológico , Pneumonia Viral/epidemiologia , Pneumonia Viral/virologia , Saúde Pública/métodos , Rede Social
2.
Health Info Libr J ; 36(4): 295-298, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31829504

RESUMO

Journal clubs are an effective means to increase skills in handling evidence and support the continuing professional development of library and knowledge services workers. This editorial examines the progression of HILJ Club, an online journal club, from an idea to the launch of a dedicated platform. One article is selected per issue of the Health Information and Libraries Journal with an open discussion invited following a brief summary and reflections by a host. Participation in HILJ Club is growing. Future success is reliant on wider engagement, and an invitation is extended to join in the discussions or even host an edition.


Assuntos
Biblioteconomia , Publicações Periódicas como Assunto , Literatura de Revisão como Assunto , Informação de Saúde ao Consumidor , Serviços de Informação sobre Medicamentos , Humanos
3.
Health Info Libr J ; 36(4): 299-317, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31617680

RESUMO

BACKGROUND: Pharmacy-led medicine information (MI) services are available in many countries to support clinicians and patients make decisions on use of medicines. OBJECTIVES: To establish what impact, if any, pharmacy-led MI services have on clinician and patient outcomes. METHODS: All published works indexed in Embase or PubMed, meeting this review's inclusion and exclusion criteria, that wholly or partially attempted to measure the effects of MI advice were retrieved and assessed. RESULTS: Twenty studies were reviewed. Five broad themes were identified describing study findings, three were specific to clinicians: their views on the effect MI answers had; actions they took; and influence on their decision making. A fourth theme centred on patient utilisation of advice, and the fifth on 'process measures' attempting to determine MI worth. DISCUSSION: Studies report on positive patient outcomes as a direct result of MI advice. Clinicians and patients acted upon the advice provided. Clinicians also reported using MI advice as a 'safety net', to check, reassure or confirm what to do. MI advice also demonstrated economic worth, although these studies are old. CONCLUSION: MI Service advice appears to affect clinician and patient outcomes. However, study design limitations require findings be viewed cautiously.


Assuntos
Tomada de Decisões , Serviços de Informação sobre Medicamentos , Serviço de Farmácia Hospitalar , Humanos , Comportamento de Busca de Informação , Resultado do Tratamento
5.
Yakugaku Zasshi ; 139(8): 1073-1079, 2019.
Artigo em Japonês | MEDLINE | ID: mdl-31366841

RESUMO

"Academic detailing" is used to clearly explain scientific issues. In the field of clinical practice, "academic detailing" is a form of interactive educational outreach to physicians in order to provide unbiased, non-commercial, evidence-based information about medications and other therapeutic modalities, with the goal of improving patient care. It is necessary to provide proper information about prescription drugs for their appropriate use in clinical practice. However, this requires of physicians significant time and labor to comprehensively collect and summarize all necessary information for the proper clinical application of pharmaceutical products, a task which may be both difficult and prohibitive to a busy physician. However, if clinical experience and other pharmaceutical or treatment information is derived solely from the commercial entities, this may lead to improper prescription practices. In western countries, public funds are used to support universities and other research institution programs. In Canada, clinical pharmacists act as "detailers". Their mission and role is to listen to the needs of the physician or health care professional, to provide objective, evidence-based drug information on selected drug therapy topics, to educate physicians on the optimal use of medications, to provide practical alternatives, and to extend the physician's usable knowledge base. The importance of this "academic detailing" activity is also recognized in Japan, and pharmacists can be expected to act as detailers in the future. We hope that this will lead to improvement in the quality of medical care.


Assuntos
Serviços de Informação sobre Medicamentos , Tratamento Farmacológico , Assistência ao Paciente , Farmacêuticos , Médicos , Medicamentos sob Prescrição , Melhoria de Qualidade , Qualidade da Assistência à Saúde , Análise Custo-Benefício , Tratamento Farmacológico/economia , Educação Médica Continuada , Humanos , Prescrição Inadequada/prevenção & controle , Medicamentos sob Prescrição/economia , Papel Profissional
6.
Yakugaku Zasshi ; 139(8): 1097-1099, 2019.
Artigo em Japonês | MEDLINE | ID: mdl-31366845

RESUMO

In the pharmaceutical industry, a Medical Affairs ("MA") professional collects, organizes and transmits information about a health care product based on the judgment of science, medicine and ethical values, thereby optimizing the product's value, improving corporate value, and assuring quality medical care. The role of the MA is to construct a "medical strategy" through the process of collecting, analyzing and evaluating information. On the other hand, Academic Detailing is "a new approach to drug information that actively disseminates drug comparison information from a pharmacological viewpoint, linking the drug's foundation to clinical practice." Cooperation between Academic Detailing and a pharmaceutical company's MA will be an essential relationship in realizing advanced prescribing proposals in the future, with the ultimate goal of optimal medication regimes for patients.


Assuntos
Indústria Farmacêutica , Serviços de Informação sobre Medicamentos , Tratamento Farmacológico , Prescrições , Garantia da Qualidade dos Cuidados de Saúde , Serviços de Informação sobre Medicamentos/tendências , Tratamento Farmacológico/tendências , Humanos
7.
Yakugaku Zasshi ; 139(8): 1101-1105, 2019.
Artigo em Japonês | MEDLINE | ID: mdl-31366846

RESUMO

In order to implement academic detailing, it is extremely important to understand the pharmacological activity of drugs based on their chemical structures. To construct a database for academic detailing, a viewpoint for clinically utilizing the fundamental pharmacological features of a drug is required. These fundamental pharmacological features include chemical characteristics such as chemical structures, physical characteristics such as pharmaceutical formulations for efficient drug delivery to target organs, and a pharmacological viewpoint, which is a mechanism by which a drug is determined to be effective. In addition, in vivo kinetics are included in a drug's pharmacological features, i.e., a drug's excretion through urine and feces via the kidneys, its side effects due to differences in enzyme type when the drug is metabolized in the liver, as well as the capacity of the patient's current enzyme profile. This review describes academic detailing based on the chemical structure of drugs for breast cancer hormone therapy, as an example.


Assuntos
Serviços de Informação sobre Medicamentos , Estrutura Molecular , Preparações Farmacêuticas/química , Farmacologia , Inibidores da Aromatase/química , Inibidores da Aromatase/uso terapêutico , Neoplasias da Mama/tratamento farmacológico , Fenômenos Químicos , Composição de Medicamentos , Sistemas de Liberação de Medicamentos , Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos , Antagonistas do Receptor de Estrogênio/química , Antagonistas do Receptor de Estrogênio/uso terapêutico , Feminino , Humanos , Fígado/metabolismo , Conformação Molecular , Farmacocinética
8.
Yakugaku Zasshi ; 139(8): 1107-1110, 2019.
Artigo em Japonês | MEDLINE | ID: mdl-31366847

RESUMO

'Academic Detailing' is an approach to providing doctors with information about medicines based on the latest non-commercial evidence-based data for proper prescription. Overseas, pharmacists have been active as academic detailers. Academic Detailing in Japan, as a new approach to disseminating comparative drug information based on basic pharmaceutical sciences and clinical evidence, will influence clinical decision making by doctors, and contribute to better patient-centered medical care. Pharmacists have been participating in ensuring the proper use of drugs by their patients by entering their homes or wards. However, in the future, it is necessary to take steps to improving pharmaceutical decision making by doctors. Therefore, we are considering the following educational points in the Japanese version of training an academic detailer. "A: We shall compare medicines based on basic pharmaceutical sciences and the latest non-commercial evidence-based data. B: We shall understand the point of using medicines based on the patient's condition. C: We shall choose cost-effective drugs from the viewpoint of pharmacoeconomics. And D: We shall acquire communication skills for effective academic detailing." In the future, this first class of Academic Detailers who facilitate academic detailing in the health care field will be pioneers. They will also participate in research to track and quantify the effects of academic detailing.


Assuntos
Serviços de Informação sobre Medicamentos , Tratamento Farmacológico , Educação Continuada em Farmácia , Prática Clínica Baseada em Evidências , Farmacêuticos , Médicos , Melhoria de Qualidade , Qualidade da Assistência à Saúde , Tomada de Decisão Clínica , Análise Custo-Benefício , Farmacoeconomia , Humanos , Prescrição Inadequada/prevenção & controle , Japão , Assistência Centrada no Paciente , Papel Profissional
9.
PLoS One ; 14(8): e0221326, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31437201

RESUMO

OBJECTIVES: To assess the impact of sources of drug information on antibiotic prescribing patterns (quantity and quality) among primary care physicians. METHODS: We conducted a cohort study on primary care physicians who were actively engaged in medical practice in 2010 in a region in north-west Spain (Galicia), fulfilling inclusion criteria (n = 2100). As the independent variable, we took the perceived utility of 6 sources of information on antibiotics, as measured by the validated KAAR-11 questionnaire. As dependent variables, we used: (1) a quality indicator (appropriate quality, defined as any case where 6 of the 12 indicators proposed by the European Surveillance of Antimicrobial Consumption Network [ESAC-Net] were better than the mean values for Spain); and, (2) a quantity indicator (high prescribing), defined as any case where defined daily doses (DDD) per 1 000 inhabitants per day of antibacterials for systemic use were higher than the mean values for Spain. The adjusted odds ratio for a change in the interquartile range (IqOR) for each sources of information on antibiotics was calculated using Generalized Linear Mixed Models. RESULTS: The questionnaire response rate was 68%. Greater perceived utility of pharmaceutical sales representatives increases the risk of having high prescribing (1/IqOR = 2.50 [95%CI: 1.63-3.66]) and reduces the probability of having appropriate quality (1/IqOR = 2.28 [95%CI: 1.77-3.01]). Greater perceived utility of clinical guidelines increases the probability of having appropriate quality (1/IqOR = 1.25 [95%CI: 1.02-1.54]) and reduces the probability of high prescribing (1/IqOR = 1.25 [95%CI: 1.02-1.54]). CONCLUSIONS: Sources of information on antibiotics are an important determinant of the quantity and quality of antibiotic prescribing in primary care. Commercial sources of information influence prescribing negatively, and clinical guidelines are associated with better indicators.


Assuntos
Antibacterianos/uso terapêutico , Atitude do Pessoal de Saúde , Serviços de Informação sobre Medicamentos/provisão & distribução , Prescrições de Medicamentos/estatística & dados numéricos , Médicos de Atenção Primária/psicologia , Padrões de Prática Médica/estatística & dados numéricos , Seguimentos , Conhecimentos, Atitudes e Prática em Saúde , Humanos , Razão de Chances , Guias de Prática Clínica como Assunto , Indicadores de Qualidade em Assistência à Saúde/estatística & dados numéricos , Espanha , Inquéritos e Questionários
11.
Psychiatry Res ; 275: 366-372, 2019 05.
Artigo em Inglês | MEDLINE | ID: mdl-31003063

RESUMO

Harmful drug-drug interactions (DDI) frequently include psychiatric drugs. Drug interaction database programs are viewed as a primary tool to alert physicians of potential DDI, but may provide different results as there is no standard to define DDI. This study compared the category of potential DDI provided by 6 commercial drug interaction database programs (3 subscription, 3 open access) for 100 drug interaction pairs. The pairs involved 94 different drugs; 67 included a psychiatric and non-psychiatric drug, and 33 included two psychiatric drugs. The category assigned to the potential DDI by the 6 programs was compared using percent agreement and Fleiss' kappa interrater reliability measure. The overall percent agreement for the category of potential DDI for the 100 drug interaction pairs was 66%. The Fleiss kappa overall interrater agreement was fair. The kappa agreement was substantial for interaction pairs with any severe category rating, and fair for interaction pairs with any major category rating. The category of potential DDI for drug interaction pairs including psychiatric drugs often differs among drug interaction database programs. Modern technology allows easy access to several interaction database programs. When assistance from a drug interaction database program is needed, the physician should check more than one program.


Assuntos
Bases de Dados Factuais/estatística & dados numéricos , Serviços de Informação sobre Medicamentos/estatística & dados numéricos , Interações Medicamentosas , Psicotrópicos/efeitos adversos , Humanos , Reprodutibilidade dos Testes
12.
Yakugaku Zasshi ; 139(4): 565-570, 2019.
Artigo em Japonês | MEDLINE | ID: mdl-30930389

RESUMO

When considering the use of pharmaceutical drugs during pregnancy and lactation, two concerns must be weighed against each other: the potential deleterious effects on the fetus and the possibility that treatment necessary for the woman but risky for the fetus either cannot be administered or else the woman must give up the pregnancy or give up nursing. The main roadblock to weighing these two concerns is a lack of evidence about what drugs are harmful to the fetus. Establishing this evidence is important to implementing the "Choosing Wisely" policy. In 2005, Japan established the Japan Drug Information Institute in Pregnancy (JDIIP), which addresses issues regarding treatments with pharmaceutical drugs during pregnancy and lactation. The JDIIP has analyzed data regarding the pregnancy results of patients who have received counseling and has conducted a registration survey, analyzed post-marketing survey data from pharmaceutical companies, and measured drug concentrations in breast milk. Currently, the JDIIP is increasing the number of targeted drugs about which it is collecting evidence. In addition, it is re-evaluating the published literature and implementing a project to revise drug packaging inserts. Pharmacists are expected to implement the "Choosing Wisely" policy regarding pharmaceutical treatment during pregnancy and lactation and to contribute to the collection of new evidence.


Assuntos
Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos/prevenção & controle , Medicina Baseada em Evidências , Prescrição Inadequada/prevenção & controle , Lactação , Sobremedicalização/prevenção & controle , Preparações Farmacêuticas , Gravidez , Serviços de Informação sobre Medicamentos , Rotulagem de Medicamentos , Feminino , Humanos , Japão , Troca Materno-Fetal , Leite Humano/metabolismo , Preparações Farmacêuticas/metabolismo , Farmacêuticos , Farmacocinética , Encaminhamento e Consulta
13.
Rev Bras Epidemiol ; 22: e190009, 2019 Mar 14.
Artigo em Inglês | MEDLINE | ID: mdl-30892472

RESUMO

INTRODUCTION: The written information on medicines has been acknowledged as an important tool for health education. OBJECTIVE: To analyze the use and understanding of medicine package inserts by users and assess sociodemographic and medical factors associated with their comprehension. METHOD: Data in this analysis are part of the PNAUM National Survey - a cross-sectional population-based study conducted in Brazil. Descriptive statistics and the Pearson χ2 tests were performed to compare proportions between sociodemographic and medical characteristics, as well as use and understanding of medicine package inserts. RESULTS: A total of 28.427 individuals responded to questions related to medicine package inserts. From these, 59.6% (95%CI 57.7 - 61.5) said they usually read the inserts, and 98.4% (95%CI 98.0 - 98.8) considered them necessary. Among people who read the medicine package inserts, more than half indicated difficulties with legibility (57.4%; 95%CI 55,2 - 59,6) and readability (54.1%; 95%CI 52.1 - 56.1). People from a lower education level reported greater difficulty in understanding them. CONCLUSION: The larger portion of the population usually read medicine package inserts. Nevertheless, people have difficulty in reading and understanding them.


Assuntos
Compreensão , Serviços de Informação sobre Medicamentos/normas , Rotulagem de Produtos , Adolescente , Adulto , Brasil , Estudos Transversais , Escolaridade , Feminino , Conhecimentos, Atitudes e Prática em Saúde , Letramento em Saúde , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem
14.
Dtsch Med Wochenschr ; 144(18): e114-e120, 2019 09.
Artigo em Alemão | MEDLINE | ID: mdl-30925622

RESUMO

BACKGROUND: A complete overview on the patient's medication is one precondition for medication safety. For this, a complete and current medication plan (MP) is an appropriate instrument. We aimed to develop and implement software to evaluate and exchange medication plans in local software systems of general practitioners (GPs) and community pharmacies (CPs). Furthermore, it was the aim to evaluate feasibility and acceptance of the defined processes. METHODS: CPs and GPs were involved to pilot the software in several steps. Additionally, they generated and updated MP according to pre-defined processes and responsibilities. Feasibility and acceptance were evaluated in a survey and a workshop. RESULTS: For the first time in Germany, the technical requirements were established to generate and exchange MP electronically. Four software systems of CPs and one software system of GPs were involved. Solved Problems were technical errors, errors relevant for medication safety, differences in display of the medication data, and limited capacity of the barcode on the MP printout. Eleven GP and CP teams recruited 196 patients. 60 % were satisfied with the defined processes. 80 % of the GPs and 63 % of CPs agreed with the defined responsibilities. GPs considered the initial compilation on patient's medication in the CP as useful. The professional exchange between GPs and CPs improved: 70 % of GPs referred to increased knowledge on medication and 88 % of CPs received more information on patients' health conditions. The structured collaboration between GPs and CPs was considered to be important (25 %) or very important (75 %) for the quality of medication plans. DISCUSSION: An electronic MP was successfully implemented for the first time in local software systems. Processes and responsibilities were accepted by both professions. These are important prerequisites for sustainably implementing the MP in daily practice.


Assuntos
Serviços de Informação sobre Medicamentos , Informática Médica , Farmacêuticos , Médicos , Alemanha , Humanos , Sistemas de Medicação no Hospital , Segurança do Paciente , Software
15.
Res Social Adm Pharm ; 15(7): 895-901, 2019 07.
Artigo em Inglês | MEDLINE | ID: mdl-30852087

RESUMO

BACKGROUND: When patient safety information is communicated across a regulatory jurisdiction or country, the potential to enhance the safety of community pharmacy practice is significant. While there currently exists a number of sources for patient safety information (e.g., websites, safety bulletins, online tools), knowledge of the barriers that may inhibit the use of such information sources within community pharmacies is limited. OBJECTIVE: This research explores community pharmacy manager use of Canadian patient safety information sources and the barriers that may limit the use of such sources. METHODS: A qualitative research study design using semi-structured interviews was conducted with 15 community pharmacy managers in the Halifax Regional Municipality of Nova Scotia, Canada. The study explored how pharmacists access and engage a variety of information sources, including corporate intranets, websites, and tools provided by third party data base repositories. Interview data were analyzed using thematic analysis. RESULTS: Five general barriers were identified: lack of time to access information sources and its contents; too many sources of available information; too much information not relevant to community pharmacy practice; complexity navigating online information sources; and lack of community pharmacy involvement in source design. CONCLUSION: While pharmacies do use safety information sources to enhance practice safety, their ability to incorporate this information is inhibited by their general lack of time available to access and read safety information, lack of knowledge about where to get this information, and lack of tailored information for the community pharmacy context. Future initiatives should address increasing information awareness of available sources, consolidating and reducing information overload of such sources, and packaging information to better fit with pharmacists' needs.


Assuntos
Acesso à Informação , Serviços Comunitários de Farmácia , Segurança do Paciente , Atitude do Pessoal de Saúde , Serviços de Informação sobre Medicamentos , Feminino , Humanos , Comportamento de Busca de Informação , Masculino , Erros de Medicação/prevenção & controle , Inquéritos e Questionários , Fatores de Tempo
16.
J Clin Pharm Ther ; 44(3): 489-492, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-30710370

RESUMO

WHAT IS KNOWN AND OBJECTIVE: Appraisal of drug information centres (DICs) is mainly by word of mouth communication and surveys of overall user satisfaction. Efforts to study the impact of this type of informatics and decision support systematically are generally lacking within the healthcare system. COMMENT: Scandinavian DICs question-answering databases are relevant sources for identifying recurring problems in pharmacotherapy, including drug safety questions, and for re-use of previous answers. Recent studies in this setting have shown that high-quality answers demand easily accessible literature sources, skills in literature search and critical assessment of the retrieved documentation. Furthermore, patient-specific advice in clinical cases presented within a requested time frame is appraised by clinicians. WHAT IS NEW AND CONCLUSIONS: Effective decision support by Scandinavian DICs depends on skills among staff and technological resources. Our experience could motivate further studies investigating methods and evaluating the impact of DICs in the healthcare system.


Assuntos
Serviços de Informação sobre Medicamentos/estatística & dados numéricos , Centros de Informação/estatística & dados numéricos , Comunicação , Bases de Dados Factuais/estatística & dados numéricos , Tomada de Decisões/fisiologia , Humanos , Inquéritos e Questionários/estatística & dados numéricos
17.
Cad Saude Publica ; 35(2): e00041018, 2019 02 18.
Artigo em Português | MEDLINE | ID: mdl-30785486

RESUMO

This article sought to evaluate the conformity between recommendations regarding antidepressant use during breastfeeding found in drug package inserts with recommendations from science-based bibliographic sources. We evaluated the standard drug package inserts of 23 antidepressants with active registration in Brazil. The presence of contraindications of antidepressant use during breastfeeding was compared with information present in the Brazilian Ministry of Health technical manual, the book Medications and Mothers' Milk and on the databases LactMed, Micromedex and UpToDate. In most drug package inserts (62.5%), antidepressants are contraindicated during breastfeeding. Among bibliographical sources, that percentage varied between 0% and 25%. The study shows a low conformity between drug package inserts and bibliographical sources, alerting to the need for revising the content and presentation of information present in antidepressant drug package inserts in Brazil.


Assuntos
Antidepressivos/efeitos adversos , Aleitamento Materno/efeitos adversos , Indústria Farmacêutica/normas , Rotulagem de Medicamentos/normas , Medicina Baseada em Evidências , Antidepressivos/administração & dosagem , Brasil , Serviços de Informação sobre Medicamentos/normas , Monitoramento de Medicamentos , Feminino , Humanos , Lactação/metabolismo , Exposição Materna/efeitos adversos , Fatores de Risco
18.
Int J Pharm Pract ; 27(3): 322-324, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-30604466

RESUMO

OBJECTIVE: Identify drug information (DI) resources used in neonatal practice guidelines in low- and middle-income countries. METHODS: Individuals with knowledge of national neonatal guideline development completed a descriptive, cross-sectional survey. KEY FINDINGS: Eighty-five per cent (33/39) of respondents fully completed the survey. Physicians from university hospitals in Africa were primary respondents. Forty-five per cent (15/33) used a single national neonatal guideline. Primary neonatal resources for drug dosing and preparation were as follows: (1) World Health Organization Pocketbook of Hospital Care for Children, (2) Pediatric & Neonatal Dosage Handbook and (3) National Institute for Health and Care Excellence for Infants and Neonatal pathways. CONCLUSION: Low- and middle-income countries with single national neonatal guidelines cite a finite range of DI resources.


Assuntos
Serviços de Informação sobre Medicamentos/normas , Neonatologia/normas , Guias de Prática Clínica como Assunto , Estudos Transversais , Países em Desenvolvimento , Pessoal de Saúde/estatística & dados numéricos , Humanos , Inquéritos e Questionários/estatística & dados numéricos
19.
J Med Libr Assoc ; 107(1): 62-71, 2019 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-30598650

RESUMO

Objective: The research evaluated point-of-care drug interaction resources for scope, completeness, and consistency in drug-ethanol and drug-tobacco content. Methods: In a cross-sectional analysis, 2 independent reviewers extracted data for 108 clinically relevant interactions using 7 drug information resources (Clinical Pharmacology Drug Interaction Report, Facts & Comparisons eAnswers, Lexicomp Interactions, Micromedex Drug Interactions, Drug Interactions Analysis and Management, Drug Interaction Facts, and Stockley's Drug Interactions). Scope (presence of an entry), completeness (content describing mechanism, clinical effects, severity, level of certainty, and course of action for each present interaction; up to 1 point per assessed item for a total possible score of 5 points), and consistency (similarity among resources) were evaluated. Results: Fifty-three drug-ethanol and 55 drug-tobacco interactions were analyzed. Drug-ethanol interaction entries were most commonly present in Lexicomp (84.9%), Clinical Pharmacology (83.0%), and Stockley's Drug Interactions (73.6%), compared to other resources (p<0.05). Drug-tobacco interactions were more often covered in Micromedex (56.4%), Stockley's Drug Interactions (56.4%), Drug Interaction Facts (43.6%), and Clinical Pharmacology (41.8%) (p<0.001). Overall completeness scores were higher for Lexicomp, Micromedex, Drug Interaction Facts, and Facts & Comparisons (median 5/5 points, interquartile range [IQR] 5 to 5, p<0.001) for drug-ethanol and for Micromedex (median 5/5 points, IQR 5 to 5, p<0.05) for drug-tobacco, compared to other resources. Drug Interaction Facts and Micromedex were among the highest scoring resources for both drug-ethanol (73.7%, 68.6%) and drug-tobacco (75.0%, 32.3%) consistency. Conclusions: Scope and completeness were high for drug-ethanol interactions, but low for drug-tobacco interactions. Consistency was highly variable across both interaction types.


Assuntos
Bases de Dados Factuais/normas , Serviços de Informação sobre Medicamentos/normas , Interações Medicamentosas , Etanol/efeitos adversos , Tabaco/efeitos adversos , Estudos Transversais , Humanos
20.
Comput Inform Nurs ; 37(1): 47-54, 2019 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-30247175

RESUMO

The Managing Medicines for People With Dementia version 2 website was developed in three languages, English, Italian, and Macedonian, to assist informal caregivers in the task of managing medications. Medication management is a complex task with potentially high stakes health outcomes, including hospitalization and death. A mixed-methods evaluation was carried out. A survey was available to site users and Web log data were collected over a 3-month period. Subsequently, the quality and suitability of the information and readability and usability of the Web site were evaluated. Focus groups and interviews were conducted with end users from all three language groups. Data collected from the evaluation surveys during the pilot test showed that users were generally satisfied with site usability (77%). The results of the readability testing indicate that future versions could be improved. Feedback from the focus groups and interviews was generally positive. The use of multiple methodologies provided comprehensive testing that is likely to have identified the majority of usability issues. Ways in which the site can be maintained with up-to-date information and be promoted to the target population, informal carers, need to be explored.


Assuntos
Cuidadores/educação , Demência/tratamento farmacológico , Serviços de Informação sobre Medicamentos , Internet , Retroalimentação , Feminino , Grupos Focais , Humanos , Masculino , Pessoa de Meia-Idade , Inquéritos e Questionários
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