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2.
Vasc Health Risk Manag ; 16: 75-85, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32214817

RESUMO

Background: We aimed to study the prevalence and outcomes of thrombophilia in acute pulmonary embolism. Methods: A retrospective observational study was conducted to include patients with a radiologically confirmed diagnosis of PE screened for thrombophilia from May 2011 to February 2015. Data included patients' demographics; clinical presentation, risk factors, laboratory investigations, management, and outcome were analyzed and compared in patients with and without thrombophilia. Results: A total of 227 cases of PE were included in the study, of which 108 (47.6%) had thrombophilia. The most frequent coagulopathic abnormality included deficiency of protein S, protein C, and antithrombin III and hyperhomocysteinemia. Only seven out of 79 patients were found to have factor V Leiden. PE patients diagnosed with thrombophilia were 10 years younger in age and peaked in the age range 30-39 years. Prior history of DVT (p=0.001) and PE (p=0.001) were the main significant risk factors in the thrombophilia group. The frequency of different risk categories of clinical probability scores did not differ significantly among those with and without thrombophilia. Pulmonary hypertension was a common complication in the thrombophilia group (P=0.009). Medications used included warfarin (74.7%), enoxaparin (73.9%), and heparin (55.4%). The overall mortality rate was 8.4%, and was non-significantly higher in the non-thrombophilia group. Conclusion: Deficiencies of protein S, protein C, and antithrombin III are the leading causes of thrombophilic defects. Patients with hereditary thrombophilia are at increased risk of acute PE, particularly among young individuals. Therefore, early detection of thrombophilic defects together with other unprovoked risk factors could reduce the risk of recurrent VTE.


Assuntos
Embolia Pulmonar/epidemiologia , Trombofilia/epidemiologia , Trombose Venosa/epidemiologia , Adulto , Idoso , Anticoagulantes/uso terapêutico , Comorbidade , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Prevalência , Embolia Pulmonar/diagnóstico , Embolia Pulmonar/prevenção & controle , Catar/epidemiologia , Recidiva , Estudos Retrospectivos , Medição de Risco , Fatores de Risco , Trombofilia/diagnóstico , Trombofilia/tratamento farmacológico , Trombofilia/genética , Resultado do Tratamento , Trombose Venosa/diagnóstico , Trombose Venosa/tratamento farmacológico
3.
Medicine (Baltimore) ; 99(1): e18569, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31895800

RESUMO

An adverse drug reactions avoidability tool called the Liverpool ADR avoidability assessment tool (LAAT) was recently developed (for research purposes), and subsequently validated with mixed interrater reliability (IRR). We investigated the comparative IRR of this tool in an inpatient cohort to ascertain its practical application in this setting.The patient population was comprised of 44 ADR drug pairs drawn from an observational prospective cohort of patents with ADR attending a Weill Cornell Medicine-affiliated tertiary medical Centre in Doha Qatar (Hamad General Hospital). Using the LAAT, and modified Hallas tools, 4 independent raters (2 Clinical Pharmacologists, and 2 General Physicians) assessed and scored the 44 ADR-drug pairs. Agreement proportions between the rating pairs were evaluated as well individual/overall kappa statistics and intraclass correlation coefficients. We evaluated the weight of each of the 7 questions on the LAAT tool to ascertain its determinative role.Across 44 ADR-drug pairs, the overall median Fleiss kappa using the LAAT, and modified Hallas tools were 0.67 (interquartile range (IQR) 0.55, 0.76), 0.36 (IQR, 0.23-0.71) respectively. The overall percentage pairwise agreement with the LAAT and modified Hallas tools were 78.5%, and 62.2% respectively. Exact pairwise agreement occurred in 37 out of 44 (range 0.71-1), and 27 of 44 (0.53-0.77) ADR-drug pairs using the LAAT and modified Hallas tools respectively. Using the LAAT tool, the overall intraclass correlation coefficient was 0.68 (CI 0.55, 0.79), and 0.37 (CI 0.22, 0.53) with the modified Hallas tool.We report a higher proportion of "possible" and "definite" avoidability outcomes of adverse drug reactions compared with the modified Hallas, or that reported by developers of the LAAT tool. Although initially developed for research purposes, our report has suggested for the first time a potential applicability of this tool in clinical environment as well.


Assuntos
Rotas de Resultados Adversos , Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos/prevenção & controle , Adulto , Algoritmos , Feminino , Humanos , Pacientes Internados/estatística & dados numéricos , Masculino , Pessoa de Meia-Idade , Variações Dependentes do Observador , Estudos Prospectivos , Catar , Reprodutibilidade dos Testes
4.
Int J Gynaecol Obstet ; 149(1): 71-75, 2020 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-31894576

RESUMO

OBJECTIVE: To assess the validity of a statistical toolkit based on the original ten-group Robson Classification of cesarean delivery. METHODS: A retrospective pilot study at Al Wakra Hospital in Doha, Qatar, was conducted from June 1 to June 30, 2017, involving consecutive women undergoing cesarean delivery, using a three-stage approach. A Microsoft Excel-based toolkit was developed by dividing each of the 10 groups of the original Robson Classification into clinical groups and subgroups. A critical review of the toolkit was then undertaken by four independent physicians based on different potential clinical scenarios that could culminate in cesarean delivery in each Robson group. The toolkit was validated by populating it with the data of the cesarean deliveries of the women involved in the study. RESULTS: The data from cesarean deliveries of 153 women were utilized in the pilot study. The toolkit catered for and successfully accommodated 94.8% of the cases without any need for change. The remaining 5.2% of cases required additional adjustments in the toolkit. The toolkit provided instant access to important data about the labor and delivery which could be used for audit and research purposes and ultimately for service improvement. CONCLUSION: The toolkit significantly improved the clinical efficacy of the Robson Classification as a potential statistical tool for comparison of local and international data.


Assuntos
Cesárea/classificação , Medição de Risco/métodos , Adulto , Cesárea/estatística & dados numéricos , Feminino , Humanos , Projetos Piloto , Gravidez , Catar , Reprodutibilidade dos Testes , Estudos Retrospectivos
5.
Chemosphere ; 247: 125886, 2020 May.
Artigo em Inglês | MEDLINE | ID: mdl-31955045

RESUMO

The agricultural industry in Qatar is highly dependent on using soil enhancing materials due to challenging soil and climatic conditions. Hence, this work investigated the potential of industrial biosludge from the wastewater treatment plant (WWTP) of a Gas-to-Liquids (GTL) plant to enhance an arid soil compared to fertilizer and compost. A fodder crop, buffel grass (Cenchrus ciliaris), was grown in semi-controlled pots containing a typical Qatari agricultural soil and admixtures over a 12-month period. The treatments included soil plus five biosludge percentage contents: 0.75, 1.5, 3, 6 and 12%. These were compared with soil only, soil plus 20-20-20 NPK fertilizer and soil plus 3% compost controls. Analyses of soil physical and chemical properties, the resulting leachate, and plant growth characteristics were conducted at set periods. The results indicate that up to 3% biosludge content led to better plant growth compared to the controls, with the optimum at 1.5% biosludge content for all growth characteristics studied. Biosludge addition to soil increased the volume of different pore types, especially micropores, which enhanced water retention and influenced plant growth. Regression modelling identified leachate Si and Fe concentrations, and biomass K content as the most influential variables for fresh biomass weight, plant height and the number of tillers, respectively. Biosludge addition to the soil around the optimum level did not cause detrimental changes to the resulting leachate and plant biomass. The findings of this work could lead to minimization of biosludge landfilling and allow for savings in fertilizers and irrigation water in arid regions.


Assuntos
Agricultura/métodos , Reciclagem , Eliminação de Resíduos Líquidos/métodos , Biomassa , Cenchrus , Fertilizantes , Catar , Solo/química , Água
6.
Scand J Med Sci Sports ; 30(3): 523-530, 2020 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-31663176

RESUMO

Training and competition loads have emerged as modifiable composite risk factors of non-contact injury. Hamstring strains are the most common injuries in football with substantial burden on the individual player and club. Nevertheless, robust evidence of a consistent load-hamstring injury relationship in professional football is lacking. Using available data from the Qatar Stars League over three competitive seasons, this study investigated the separate and combined effects of perceived exertion and session duration on hamstring injury occurrence in a sample of 30 outfield football players. Load variables were calculated into 7-day, 14-day, 21-day, 28-day periods of data, and week-to-week changes for average ratings of perceived exertion (RPE; au) score and session-RPE (s-RPE; session-duration  ×  score), plus the cumulative training and match minutes and s-RPE, respectively. Conditional logistic regression models estimated load-injury relationships per 2-within-subject standard deviation increments in each candidate variable. Associations were declared practically important based on the location of the confidence interval in relation to thresholds of 0.90 and 1.11 defining small beneficial and harmful effects, respectively. The uncertainty for the corrected odds ratios show that typically high within-subject increments in each candidate variable were not practically important for training- and match-related hamstring injury (95% confidence intervals range: 0.85 to 1.16). We found limited exploratory evidence regarding the value of perceived exertion and session duration as etiological factors of hamstring injury in Middle-East professional football. Monitoring remains valuable to inform player load management strategies, but our exploratory findings suggest its role for type-specific injury risk determination appears empirically unsupported.


Assuntos
Traumatismos em Atletas/etiologia , Músculos Isquiossurais/lesões , Futebol/lesões , Carga de Trabalho , Atletas , Humanos , Masculino , Catar , Fatores de Risco , Fatores de Tempo
7.
Food Chem ; 310: 125591, 2020 Apr 25.
Artigo em Inglês | MEDLINE | ID: mdl-31837531

RESUMO

In this research, effect of soaking time, acidity and temperature on the removal of lead and cadmium from rice was investigated. Different rice treatments were involved i.e. three soaking times (0, 15, and 30 min), three temperatures (20, 25, and 30 °C) and four concentrations of glacial acetic acid (0.5%, 1%, 2%, and 3%). Results showed that few samples have shown lead concentrations above the maximum limit set by the World Health Organization (WHO) and the UN Food and Agriculture Organization (FAO) of 0.2 mg/kg, whereas, all cadmium concentrations were below the limit of 0.4 mg/kg. A decrease in lead and cadmium concentrations were observed with increasing time of soaking. Lead had the lowest concentration at 20 °C, while cadmium had the lowest concentration at 30 °C. Cadmium concentration decreased with increasing water acidity, while the lead concentration reached the lowest concentration with 1% acidity.


Assuntos
Cádmio/isolamento & purificação , Contaminação de Alimentos/prevenção & controle , Chumbo/isolamento & purificação , Oryza/química , Ácido Acético/química , Cádmio/análise , Contaminação de Alimentos/análise , Chumbo/análise , Catar , Temperatura
8.
Arch Environ Occup Health ; 75(1): 10-17, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-30449263

RESUMO

This article explores predictors of job satisfaction and stress among clinicians and administrative staff at the public health sector in the State of Qatar. This is a rapidly growing sector, aiming for excellence in service, education and research. The vast majority of the staff are expatriates with different cultural backgrounds, and varying qualifications. After obtaining ethical approvals to conduct the study, the target population were asked to complete an anonymous online survey, that included sociodemographic data followed by the National Institute for Occupational Safety and Health (NIOSH) generic Job Stress questionnaire. Total number included in the analysis is 1260, female, married with children. Role ambiguity, conflict, skill underutilization and workload were associated with job dissatisfaction. Role and job future ambiguity were significantly associated with depression.


Assuntos
Esgotamento Profissional/epidemiologia , Pessoal de Saúde/estatística & dados numéricos , Satisfação no Emprego , Adulto , Esgotamento Profissional/psicologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Catar/epidemiologia , Fatores de Risco , Adulto Jovem
9.
Disasters ; 44(1): 63-84, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31538674

RESUMO

The 2017 Gulf crisis is one of the most challenging episodes faced by Qatar since its independence in 1971, with major economic, social, and political impacts on the Arab Gulf nation. Its economic prognosis has been brought into doubt, the map of regional alliances has been redrawn, and any prospects of deeper regional integration have been dashed. This paper analyses the little-documented impact of the crisis on Qatar's humanitarian sector, which has unfolded as the small, gas-rich emirate has striven to become a major humanitarian donor. It concludes that while there have been disruptions to humanitarian operations and regional coordination, the Gulf crisis has triggered and in some cases accelerated already intended reforms across the Qatari humanitarian sector. In the long term, the reorganisation and adaptation implemented to weather the storm of the crisis may help Qatar to emerge from the crisis with a more sustainable and resilient humanitarian sector.


Assuntos
Conflitos Armados , Socorro em Desastres/organização & administração , Humanos , Catar
10.
Teach Learn Med ; 32(1): 91-103, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31339363

RESUMO

Construct: The globalization of healthcare has been accentuated by the export of health professional curricula overseas. Yet intact translation of pedagogies and practices devised in one cultural setting may not be possible or necessarily appropriate for alternate environments. Purposeful examination of workplace learning is necessary to understand how the source or "home" program may need adapting in the distributed or "host" setting. Background: Strategies to optimize cross-border medical education partnerships have been largely focused on elements of campus-based learning. Determining how host clinical supervisors approach assessment in experiential settings within a different culture and uphold the standards of home programs is relevant given the influence of context on trainees' demonstrated competencies. In this mixed-methods study, we sought to explore assessor judgments of student workplace-based performance made by preceptors sharing a pharmacy curriculum in Canada and Qatar. Approach: Using modified Delphi consensus technique, we asked clinical supervisors in Canada (n = 18) and in Qatar (n = 14) to categorize trainee performance as described in 16 student vignettes. The proportion of ratings for three levels of expectation (exceeds, meets, or below) was calculated and within-country group consensus achieved if the level of agreement reached 80%. Between-country group comparisons were measured using a chi-square statistic. We then conducted follow-up semi-structured interviews to gain further perspectives and clarify assessor rationale. Transcripts were analyzed using thematic content analysis. Results: The threshold for between-country group differences in assessor impressions was met for only two of the 16 student vignettes. Compared to Canadian clinical supervisors, relatively more preceptors in Qatar judged one described student as meets rather than exceeds expectations and one as meets rather than falls below expectations. Analysis of follow-up interviews exploring how culture may inform variations in assessor judgments identified themes associated with the profession, organization, learner, and supervisor performance theories but not their particular geographic context. Clinical supervisors in both countries were largely aligned in expectations of student knowledge, skills, and behaviors demonstrated in patient care and multidisciplinary team interactions. Conclusions: Our study demonstrated that variation in student assessment was more frequent among clinical supervisors within the same national context than any differences identified between the two countries. In these program settings, national sociocultural norms did not predict global assessor impressions or competency-specific judgments; instead, professional and organizational cultures were more likely to inform student characterizations of performance in workplace-based settings. Further study situated within the specific experiential learning contexts of cross-border health professional curricula is assuredly warranted.


Assuntos
Currículo , Ocupações em Saúde/educação , Preceptoria , Local de Trabalho , Canadá , Competência Clínica/normas , Técnica Delfos , Feminino , Humanos , Masculino , Cultura Organizacional , Profissionalismo , Catar
11.
Nurse Educ Today ; 84: 104235, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31706203

RESUMO

BACKGROUND: In today's health care context, nurse educators teach with limited clinical placement availability, competition for available spaces and increasingly complex clients. SETTING: As part of the baccalaureate of nursing program at the University of Calgary in Qatar, students are required to complete 208 h of maternal-child clinical. Unfortunately, due to social and cultural norms in this predominantly Muslim country, male nursing students are prohibited from practicing with mothers and babies in Qatar. In order to address this need, we developed a fully simulated clinical practice module for these male students. OBJECTIVES: The aim of the current study was to better understand the learning experiences of the students undertaking this experience. DESIGN: The authors developed and implemented a fully simulated, campus-based, maternity clinical experience that used a variety of levels of fidelity, incorporated the tenets of Kolb's (1984) experiential learning theory, and Jeffries' (2005) simulation design framework. Post-simulation debriefing sessions were recorded and transcribed. Typed weekly reflections were provided. All data was blinded. PARTICIPANTS: A convenience sample of ten adult, male participants was obtained. METHODS: Using an inductive qualitative approach, researchers analyzed transcripts of debriefing sessions and reflective journals. RESULTS: The main themes were knowledge application, clinical judgement, communication, and crossing cultural barriers. CONCLUSIONS: Themes from this study can be used to support and/or change existing practices in a way that supports learner-centered, experiential teaching practices.


Assuntos
Currículo , Enfermeiros , Enfermagem Obstétrica/educação , Simulação de Paciente , Estudantes de Enfermagem , Características Culturais , Bacharelado em Enfermagem , Feminino , Humanos , Entrevistas como Assunto , Masculino , Gravidez , Catar
12.
Clin Interv Aging ; 14: 1889-1899, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31802859

RESUMO

Purpose: To assess the prevalence and associated risk of potentially inappropriate prescribing (PIP) in older adults. Methods: This was a national 3-year retrospective study of outpatient older adults exposed to potentially inappropriate medication (PIM) or polypharmacy. We used the Beers Criteria 2019 list to identify PIM to be avoided in older adults. We define moderate polypharmacy (MoP) and major polypharmacy (MaP) as using 6-10 or >10 chronic medications, respectively. Determinants of PIP included patients' demographics, lab results, medications, comorbidities, and home healthcare services. We used Chi-square (for categorical variables), Unpaired t-test and ANOVA (for continuous variables as applicable) to assess the association of these determinants with PIP. Univariate followed by multivariate logistic regression models were used to get the crude and adjusted odds ratios of exposure to PIM or polypharmacy within patients who had emergency department (ED) admissions, bone fractures, falls, or constipation, compared to those who had not. Results: 3537 patients were included. 62.6%, 40.4%, and 27.2% were exposed to PIM, MoP and MaP, respectively. Determinants of PIP included age, gender, ethnicity, weight, kidney function, sodium levels, hypertension, diabetes, heart failure, CAD, and home healthcare services (all with p-value < 0.05). PIM was associated with risk of ED admission, bone fracture and constipation with adjusted OR (p-values) of 1.27 (0.002), 1.33 (0.005), and 1.40 (<0.001), respectively. MoP was associated with the risk of ED admission, bone fracture, and constipation, with adjusted OR (p-values) of 1.27 (0.012), 1.34 (0.019), and 1.47 (<0.001), respectively. MaP was associated with a higher risk of ED admission, bone fracture, falls, and constipation with adjusted OR (p-values) of 1.46 (0.001), 1.59 (0.002), 1.39 (0.023), and 2.07 (<0.001), respectively. Conclusion: PIP is common and is associated with an increased risk of poor clinical outcomes in older adults.


Assuntos
Serviços de Assistência Domiciliar/organização & administração , Prescrição Inadequada/estatística & dados numéricos , Polimedicação , Lista de Medicamentos Potencialmente Inapropriados/estatística & dados numéricos , Idoso , Idoso de 80 Anos ou mais , Comorbidade , Estudos Transversais , Feminino , Humanos , Modelos Logísticos , Masculino , Padrões de Prática Médica/estatística & dados numéricos , Prevalência , Catar , Estudos Retrospectivos , Fatores de Risco
13.
Biopreserv Biobank ; 17(6): 506-511, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31833808

RESUMO

Qatar Biobank (QBB) is a platform that will make vital health research possible through its collection of samples and information on health and lifestyle from the local population of Qatar. The goal of QBB is to collect, process, store, and finally share high-quality biological samples and associated data for research purposes with the research community. To do this, a series of standardized procedures following evidence-based practices are required, and QBB is achieving this by implementing an integrated management system (IMS) that incorporates ISO 9001: 2015 and ISO 27001: 2013 standards. ISO 9001 is one of the most commonly implemented quality management systems as it is applicable to any size of organization. ISO 27001: 2013 is increasingly popular as organizations look to manage their data and information security, especially in the light of the recent General Data Protection Regulation legislation and an ever-changing digital landscape. QBB has achieved certification in both ISO 9001: 2015 (originally 2008 standard) and ISO 27001: 2013 since 2014. In 2016, during preparations for recertification of both standards in 2017, QBB chose to integrate both of the management systems in preference to running them in parallel, without compromising the goals and objectives of QBB. The IMS has ensured that rigorous processes and controls are implemented to not only manage the quality of internal and external processes and services provided, but the privacy and confidentiality of data collected during a participant visit are consistently protected as well as a proactive approach to identifying and managing risk within the organization. This article will explore the impact of implementing an IMS on the continuous improvement of services within QBB.


Assuntos
Bancos de Espécimes Biológicos/organização & administração , Prática Clínica Baseada em Evidências/métodos , Bancos de Espécimes Biológicos/normas , Humanos , Catar , Integração de Sistemas
14.
Biopreserv Biobank ; 17(6): 494-505, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31833809

RESUMO

The overall goal of the Qatar Biobank (QBB) is to collect, manage, and distribute high-quality human biospecimens with appropriate clinical and/or research annotation and associated phenotypic data, aiming to be an important and essential resource of medical research and evidence-based health care system policies in Qatar. To manage and collect large volumes of data, the QBB has been investing in a number of information management solutions, trying to avoid inflexibility of traditional systems and accommodate changes in data sources and workflows. This article aims to present the information technology solutions of QBB based on a free, open-source software solution, considered a reliable alternative to commercial solutions. After evaluating the free, open-source software solutions available for biobanks, Onyx from ObiBa was utilized to develop custom components to interface various clinical devices, LIMS and Picture Archiving and Communication System, which has varying integration capabilities. This is a showcase for biobanks to carefully evaluate and select hardware and software to automate their operations providing the functions required for business continuity.


Assuntos
Bancos de Espécimes Biológicos/organização & administração , Bancos de Espécimes Biológicos/normas , Assistência à Saúde , Prática Clínica Baseada em Evidências , Humanos , Gestão da Informação , Tecnologia da Informação , Catar , Software
16.
Biopreserv Biobank ; 17(6): 491-493, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31833811

RESUMO

Biobank science is progressively becoming indispensable for the development of novel diagnostic tools in health care, by pairing standardized high-quality biological samples, phenotypic, and omics data required to best characterize the underlying biological mechanisms of response to therapy and survival. Qatar Biobank (QBB), Qatar's National Repository Centre for biological samples and health information, aligning with these endeavors, has developed a strategic framework to enable biobanking science that can be transformed into tangible health care diagnostic tools. In this concept, QBB works closely with multidisciplinary stakeholders: (1) governmental authorities (n = 2), (2) health providers (n = 3), (3) academic institutions (n = 28), (4) other research institutions (n = 6), and (5) the Qatar National Research Fund, by providing data and biospecimens to research projects. The local community organizes campaigns through social media and interactive events, spreading the concept of biobanking to inform and encourage people to participate. Up to now, QBB has recruited up to 30% of the targeted population and collaborated with 35 national and international research entities contributing to more than 170 research projects. QBB is referring about 53% of its participants to the Hamad general hospital through the integrated information system, revealing the need of new health screening approaches for public health policy makers. QBB contributed to the development of a customized genetic screening microarray tailored to the Qatari population that will be used in research as well as for the screening of variants of medical relevance in Qatar, promoting precision medicine in Qatar's health care system. The QBB strategic plan is a paradigm for the optimal utilization of resources, infrastructure, and investments engaging the local authorities and the research entities, and committing them to data sharing and working together toward the discovery of evidence-based health care interventions.


Assuntos
Bancos de Espécimes Biológicos , Prática Clínica Baseada em Evidências/métodos , Humanos , Disseminação de Informação , Cooperação Internacional , Medicina de Precisão , Catar , Pesquisa Médica Translacional
17.
Biopreserv Biobank ; 17(6): 487-490, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31833812

RESUMO

The International Biobanking Conference titled "Quality Matters: A Global Discussion in Qatar" was held on March 25-27, 2019, in the vibrant city of Doha, Qatar. The 3-day event was organized and hosted by the Qatar Biobank (QBB) and the European, Middle Eastern and African Society for Biopreservation and Biobanking (ESBB), with supporting collaboration from the International Society for Biological and Environmental Repositories (ISBER) and the Biobanking and BioMolecular Resources Research Infrastructure-European Research Infrastructure Consortium (BBMRI-ERIC). The aim was to highlight the role of biobanking in medical research and advancing health care, as well as improving clinical outcomes. The conference convened experts from across the globe to discuss continuing efforts to harmonize biobanking-related processes to achieve high-quality standards and to support international advancements in medical research for our diverse populations. The scientific agenda drew more than 1000 scientists, researchers, industry experts, and health professionals from five continents. The conference focused on the quality aspect of biobanking through seven sessions over 3 days. Researchers, scientists, and experts from around the world were invited to present, and included special presentations from QBB demonstrating their standing as a leading clinical biobank innovator in support of population and genomic medicine. The 3-day conference concluded with a session on Best Practices and Standards, a topic much in discussion with today's context.


Assuntos
Bancos de Espécimes Biológicos/normas , Congressos como Assunto , Genômica , Humanos , Cooperação Internacional , Catar
18.
BMC Health Serv Res ; 19(1): 973, 2019 Dec 18.
Artigo em Inglês | MEDLINE | ID: mdl-31852546

RESUMO

BACKGROUND: Cardiovascular diseases are the leading cause of death in Lebanon and Qatar. When lifestyle modifications prove insufficient, medication becomes a cornerstone in controlling such diseases and saving lives. Price, availability, and affordability hinder the equitable access to medicines. The study aimed to assess prices, availability, and affordability of essential cardiovascular disease medicines in relation to pricing strategies in Qatar and Lebanon. METHODS: A cross-sectional survey using a variant of the World Health Organization and Health Action International (WHO/HAI) methodology as outlined in "Measuring medicine prices, availability, affordability and price components" (2008), second edition, was adopted. Prices and availability of 27 cardiovascular medicines were collected from public and private dispensing outlets. For international comparison, prices were adjusted to purchasing power parity. Data was analyzed across multiple sectors, within and across countries. RESULTS: A total of 15 public and private outlets were surveyed in each country. Prices were more uniform in Qatar than in Lebanon. In the public sector, medicines were free-of-charge in Lebanon and priced lower than the international reference prices in Qatar. The ratio of medicine unit price to international reference price in the private sectors surveyed are significantly higher than the acceptable threshold of 4. This ratio of originator brands and lowest priced generics in Qatar were up to two and five times those in Lebanon, respectively, even after adjusting for purchasing power parity. However, prices of lowest priced generics in the private sector were at least 35% cheaper in Qatar and 65% cheaper in Lebanon than their comparative originator brands. Medicines were more available in the private sector in Lebanon than in Qatar, but only the originator brand availability in the public sector in Qatar exceeded the WHO target of more than 80%. While affordable in the public sector in Qatar, four out of thirteen medicines exceeded the threshold in all private sectors covered. Hence, only the public sector in Qatar had a satisfying level of availability and affordability. CONCLUSIONS: Except for the Qatari public sector, medicine prices, availability, and affordability are falling short from targets. Key policy decisions should be implemented to improve access to medicines.


Assuntos
Fármacos Cardiovasculares/economia , Fármacos Cardiovasculares/provisão & distribução , Doenças Cardiovasculares/tratamento farmacológico , Comércio/estatística & dados numéricos , Custos e Análise de Custo/estatística & dados numéricos , Estudos Transversais , Medicamentos Essenciais/economia , Medicamentos Essenciais/provisão & distribução , Medicamentos Genéricos/economia , Medicamentos Genéricos/provisão & distribução , Humanos , Líbano , Setor Privado/estatística & dados numéricos , Setor Público/estatística & dados numéricos , Catar , Inquéritos e Questionários
19.
Med Sci (Paris) ; 35 Hors série n° 2: 15-17, 2019 Nov.
Artigo em Francês | MEDLINE | ID: mdl-31859625

RESUMO

Congenital myopathies represent a quite heterogeneous group of neuromuscular disorders both at the clinical and genetic level. High-throughput sequencing (NGS), targeted or not, combined with muscle pathology, greatly facilitate their accurate characterization and occasionally lead to unexpected discoveries like in the case reported here in a Kuwaiti family facing a long diagnostic odyssey.


Assuntos
Proteínas Adaptadoras de Transdução de Sinal/genética , Fissura Palatina/diagnóstico , Hipertermia Maligna/diagnóstico , Mutação de Sentido Incorreto , Miotonia Congênita/diagnóstico , Miotonia Congênita/genética , Adolescente , África , Grupo com Ancestrais do Continente Africano/genética , Substituição de Aminoácidos , Criança , Fissura Palatina/genética , Análise Mutacional de DNA , Diagnóstico Diferencial , Sequenciamento de Nucleotídeos em Larga Escala , Homozigoto , Humanos , Kuweit , Masculino , Hipertermia Maligna/genética , Miotonia Congênita/patologia , Fenótipo , Catar , Arábia Saudita , Irmãos
20.
East Mediterr Health J ; 25(11): 813-819, 2019 Nov 25.
Artigo em Inglês | MEDLINE | ID: mdl-31782518

RESUMO

Background: Hospital-based surveillance has proved useful in determining the incidence of infectious diseases. Aims: This study aimed to describe the epidemiological characteristics of reported cases and specific performance indicators of the surveillance system. Methods: A descriptive study of reported communicable diseases was carried out in The Cuban Hospital (Qatar) during January 2012 to December 2013. A multidimensional communicable diseases surveillance approach was used. Information of epidemiological variables, laboratory confirmation and notification date were collected. We calculated the proportion of cases with laboratory confirmation and time between the report by the physician and notification to the Supreme Council of Health. Results: A total of 1065 patients were reported; 802 (75.3%) male with a mean age of 33.2 (standard deviation 15.4) years. There was a predominance of cases from Southeast Asia (41.5%) and Eastern Mediterranean Region (16.7%). There were 539 cases of influenza-like illness, 186 of skin infectious diseases, 66 of scabies, 48 with multidrug-resistant organisms, and 39 cases of diarrhoea of presumed infectious etiology. A steady increase in laboratory confirmation was observed (mean 59.3%). Timing for notification to the Supreme Council of Health was 1.88 (2.9) days. Conclusion: The implemented hospital-based surveillance system was feasible and delivered important insights into the epidemiological characteristic of communicable diseases in a western community in Qatar.


Assuntos
Doenças Transmissíveis/epidemiologia , Administração Hospitalar , Vigilância da População/métodos , Adulto , Notificação de Doenças/métodos , Feminino , Humanos , Incidência , Capacitação em Serviço , Masculino , Pessoa de Meia-Idade , Catar/epidemiologia
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