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West Indian med. j ; 50(suppl 7): 47, Dec. 2001.
Artigo em Inglês | MedCarib | ID: med-52


The Mexican yam bean (Pachyrhizus erosus) is a tuberous legume native to Central America. This species shows great potential for development as a food crop, to increase the existing limited base of staples that make up the diet in tropical regions, producing both protein rich grain and starch producing tubers. Starch quality is good due to its high digestibility. The major limitation to its use as a staple crop, however, is the low starch content of the tubers. The low variability of the existing gene pool for the genus limits the use of conventional plant breeding for improvement of the crop. Genetic engineering for crop improvement is, therefore adopted. The molecular genetics of carbohydrate metabolism in tubers of the Mexican yam bean is being studied. The result of such studies will guide the application of genetic engineering technology to improve starch content of the tubers. The work reported here describes the cloning of putative genes for the large subunit of ADP-glucose pyrophosphorylase (Agp2) from yam bean tubers. A cDNA library was constructed from RNA isolated from two-month-old yam bean tubers. A probe for Agp2 was prepared by RTPCR analysis of the tuber RNA preparations, using degenerate primers. Four clones, which hybridized to the probe, were isolated for further characterization. (AU)

Ciências da Nutrição , Fabaceae/genética , Fabaceae/metabolismo , Carboidratos/metabolismo , Produtos Agrícolas
West Indian med. j ; 35(Suppl): 45, April 1986.
Artigo em Inglês | MedCarib | ID: med-5932


In former days, Curacaoan beans were commonly used. Nowadays, these beans are mainly replaced by food rich in simple carbohydrates and fat. We therefore investigated whether a diet rich in beans might facilitate the metabolic control of gestational diabetes mellitus. We compared the effect of consuming 5 locally grown beans (Bonchi Cora, Bonchi Pela Berde, Wandu, Bonchi Wowo Pretu and Bonchi di Kunuku) on the blood glucose response in non-pregnant, healthy pregnant and diabetic pregnant women. The area under the incremental blood glucose 3-hr curve, after consuming 25 gm of each type of bean, was expressed as a percentage of the blood glucose area obtained after a 25 gm bread-and-cheese breakfast. The mean of these values for each food was designed as the "glycaemic index, G.I." for that food. All beans showed a lower glycaemic index than the test bread meal. We found lower glycaemic indexes in both the healthy pregnant and diabetic pregnant women than in non-pregnant women. It is possible that gestational diabetics (and other diabetics) will be more easily controlled with "old fashioned" tasty bean-meals prepared with locally grown products than with refined foods (AU)

Humanos , Feminino , Gravidez , Fabaceae , Diabetes Mellitus/sangue , Glicemia/metabolismo
Trop Geogr Med ; 30(1): 5-21, Mar. 1978.
Artigo em Inglês | MedCarib | ID: med-12673


The West Indies, and associated parts of the Caribbean area, are extremely diverse and afford interesting examples for the study of geographical medicine. Short accounts are given of some conditions whose aetiologies have been relatively recently clarified, including vomiting sickness of Jamaica, veno-occlusive disease of Jamaica, blackfat pulmonary fibrosis of Guyana, and epidemic acute glomerulonephritis of Trinidad. The aetiology of tropical sprue, which is common in Puerto Rico and absent from Jamaica remains to be explained although a hypothesis has been put forward. Further work is needed to establish the geographical distribution of idiopathic cardiomegaly and the spinal neuropathies and associated syndromes of retrebublar neuritis and sensorineural deafness before their aetiologies can be understood (AU)

Humanos , Criança , Adulto , Medicina Tropical , Doenças Ósseas/epidemiologia , Glomerulonefrite/epidemiologia , Cardiomegalia/epidemiologia , Hipoglicinas/envenenamento , Fabaceae/envenenamento , Doenças do Sistema Nervoso/epidemiologia , Intoxicação por Plantas/epidemiologia , Fibrose Pulmonar/etiologia , Tabagismo , Espru Tropical/epidemiologia , Infecções Estreptocócicas/epidemiologia , Streptococcus pyogenes , Síndrome , Guiana , Jamaica , Porto Rico , Trinidad e Tobago , Índias Ocidentais
St. Augustine; Caribbean Food and Nutrition Institute; Mar. 1977. iv,80 p. tab. (CFNI-T-8-77).
Monografia em Inglês | MedCarib | ID: med-6845
Carib Med J ; 37(2&3): 31-2, 1976. ills
Artigo em Inglês | MedCarib | ID: med-4359
Cajanus ; 6(1): 6-10, Mar. 1973.
Artigo em Inglês | MedCarib | ID: med-11955
Pl Fds Hum Nutr ; 2(3-4): 145-6, 1972.
Artigo em Inglês | MedCarib | ID: med-12099


In the last few decades, the field of public health has seen the development of many monovalent, simplicist, would-be universal approaches to complex problems, whose etiology varies from region to region-most have been unsuccessful. Current planners plainly appreciate the need for programs tailored to local circumstances and possibilities (including the young child population both in rural and urban areas), and the need for many channelled approaches in every situation. In addition to the amino acid fortification of foods and the development of new protein processed foods by modern technology, opportunities for amino acid reinforcement by combinations of traditional foods must receive major emphasis in any community nutrition program, especially for home produced weaning foods. To lay sole emphasis on one or other of these approaches is plainly imbalanced-a combination of approaches are vitally needed. They are not in competition, but mutually reinforcing. (Summary)

Humanos , Proteínas na Dieta , Aminoácidos Essenciais , Grão Comestível , Fabaceae , Plantas
Cajanus ; 2(2): 103-111, 1969.
Artigo em Inglês | MedCarib | ID: med-12031
West Indian med. j ; 13(1): 1-11, Mar. 1964.
Artigo em Inglês | MedCarib | ID: med-10637


The content of cyanogenetic glucosides in West Indian and other pulses was estimated by the release of hydrocyanic acid on hydrolysis. In the varieties of phaseolus lunatus (lima bean) examined, the CN content was under 20mg. per cent, and not of the order previously known to cause acute poisoning. Trace amounts were found in 5 other species, and a high content was found in a variety of vicia sativa seeds (common vetch). A comparison of hydrolytic procedures in ph. lunatus showed that whereas the cyanogenetic glucoside is stable on cooking the intact bean, neither human saliva nor dilute hydrochloric acid at 37oC was effective in releasing free HCN from beans crushed after cooking. Animal feeding tests of crushed uncooked beans showed that the toxicity of these varieties was unrelated to their CN content. Severe 'toxicity' of ph. vulgaris (kidney bean, red pea) in rats and guinea pigs was mainly, if not entirely, due to unpalatability, causing starvation. Palatability was much improved by cooking. Absorption and utilisation of other species were good when fed to rats, even at 50 per cent level. There was some evidence of pancreatic hypertrophy and of impaired absorption or utilization of vigna sp. (black-eye pea) and cajanus cajan (gungo pea) in guinea pigs. No neurological lesions were detected in rats in feeding tests of up to 6 month's duration (AU)

21003 , Cianetos/toxicidade , Fabaceae/toxicidade , Cianeto de Hidrogênio/toxicidade
St. Augustine; Caribbean Food and Nutrition Institute; s.d. 11 p. tab. (CFNI-T-31-79).
Monografia em Inglês | MedCarib | ID: med-15112


This paper contends that the importance of grain legumes in human nutrition in the Caribbean or elsewhere lies in their ability to supplement diets and in their potential for solving food and nutrition problems in the Region. The grain legumes are sources of energy, protein, minerals (including iron and calcium) and vitamins. They may have been used in human diets for over 10,000 years

Humanos , Fabaceae , Consumo de Alimentos , Índias Ocidentais